Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

European Journal of Neuroscience

Volumn 22, Issue 11, 2005, Pages 2755-2764

  Ericson, Cecilia ^a   Georgievska, Biljana ^a   Lundberg, Cecilia ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

6 hydroxydopamine; Dopamine; Gene therapy; Glial cells; Transplantation; Tyrosine hydroxylase

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LENTIVIRUS VECTOR; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINERGIC NERVE CELL; FEMALE; GENE EXPRESSION; GENE TARGETING; LENTIVIRINAE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA; TRANSGENE;

AMPHETAMINE; ANIMALS; ASTROCYTES; CELL COUNT; CELL TRANSPLANTATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; NERVE FIBERS; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; STEREOTYPED BEHAVIOR; SUBSTANTIA NIGRA; SYMPATHOLYTICS; TRANSDUCTION, GENETIC;

EID: 29144536727     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04503.x     Document Type: Article

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