Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: Inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways

Journal of Pharmacological Sciences

Volumn 116, Issue 2, 2011, Pages 221-231

  Lim, Hyun ^a   Park, Haeil ^a   Kim, Hyun Pyo ^a  

^a Kangwon National University   (South Korea)

Author keywords

2 ,3 ,5,7 tetrahydroxyflavone; Activator of transcription; Apigenin; Flavonoid; Matrix metalloproteinase 13; Signal transducer

Indexed keywords

2',3',5,7 TETRAHYDROXYFLAVONE; APIGENIN; COLLAGENASE 3; FLAVONOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; JANUS KINASE 2; KAEMPFEROL; NARINGENIN; PROTEIN C FOS; QUERCETIN; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; WOGONIN;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; EXPERIMENTAL RABBIT; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MALE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

EID: 79959348345     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.11014FP     Document Type: Article

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