Icariin protects murine chondrocytes from lipopolysaccharide-induced inflammatory responses and extracellular matrix degradation

Nutrition Research

Volumn 30, Issue 1, 2010, Pages 57-65

  Liu, Man Hai ^a   Sun, Jui Sheng ^a,b   Tsai, Shaio Wen ^a   Sheu, Shiow Yunn ^a   Chen, Ming Hong ^c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Chondrocytes; COX 2; Gene expression; Icariin; Inflammation; iNOS; Mice; MMPs

Indexed keywords

COLLAGEN; COLLAGENASE 3; CYCLOOXYGENASE 2; GLYCOSAMINOGLYCAN; HYDROXYPROLINE; ICARIIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERSTITIAL COLLAGENASE; LIPOPOLYSACCHARIDE; STROMELYSIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL ARTHRITIS; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG SAFETY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; IN VITRO STUDY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, INFECTIOUS; CELL SURVIVAL; CHONDROCYTES; COLLAGEN; EPIMEDIUM; EXTRACELLULAR MATRIX; FLAVONOIDS; GLYCOSAMINOGLYCANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASES, SECRETED; MICE; NITRIC OXIDE; PHYTOTHERAPY; PLANT EXTRACTS;

EPIMEDIUM PUBESCENS; MURINAE; MUS;

EID: 74549165945     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2009.10.020     Document Type: Article

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