Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 5, 2004, Pages 1165-1167

  Dao, Tran Thanh ^a   Chi, Yeon Sook ^a   Kim, Jeongsoo ^a   Kim, Hyun Pyo ^a   Kim, Sanghee ^b   Park, Haeil ^a  

^a Kangwon National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Anti inflammatory activity; Chrysin derivatives; COX 2; Prostaglandin production

Indexed keywords

ACETOPHENONE DERIVATIVE; CHRYSIN; CYCLOOXYGENASE 2 INHIBITOR; LIPOPOLYSACCHARIDE; PROSTAGLANDIN;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; EVALUATION; HYDROXYLATION; MOUSE; NONHUMAN; PROSTAGLANDIN SYNTHESIS;

EID: 1242339553     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.087     Document Type: Article

References (15)

1. Needleman P., Isakson P. J. Rhematol. 24(Suppl. 49):1997;6.
2. Middleton, E.; Kandaswami, C. In The Flavonoids: Advances in Research Since 1986; Harborne, J. B., Ed.; London, 1994; 619.
3. Chi Y.S., Jong H.G., Son K.H., Chang H.W., Kang S.S., Kim H.P. Biochem. Pharmacol. 62:2001;1185.
4. Liang Y.-C., Huang Y.-T., Tsai S.-H., Shiau S.-Y., Chen C.-F., Lin J.-K. Carcinogenesis. 20:1999;1945.
5. Kim Y.P., Yamada M., Lim S.S., Lee S.H., Ryu N., Shin K.H., Okuchi K. Biochim. Biophys. Acta. 1438:1999;399.
6. Chi Y.S., Cheon B.S., Kim H.P. Biochem. Pharmacol. 61:2001;1195.
7. Chan E.C.H., Patchareewan P., Owen L.W. J. Cardiovasc. Pharmacol. 35:2000;326.
8. Zanoli P., Aallone R., Baraldi M. Filtoterapia. 71:2000;117.
9. Leu Y.L., Ho D.K., Cassady J.M., Cook V.M., Baird W.M. J. Nat. Prod. 55:1992;357.
10. Fishkin R.J., Winslow J.T. Psychopharmacology(Berl). 132:1997;335.
11. Nakazawa K. Chem. Pharm. Bull. 10:1962;1032.
12. Kosmeder, J. W.; Moriarty, R. M.; Pezzuto, J. M.; Song, L.L.; Moon, R. C. US Patent 6,046,231, 2000.
13. Parker K.A., Petraitis J.J. Tetrahedron Lett. 22:1981;397.
14. Vickery E.H., Pahler L.F., Eisenbraun E.J. J. Org. Chem. 44:1979;4444.
15. Mossman T. J. Immunol. Methods. 65:1983;55.