Competition between Li+ and Mg2+ in metalloproteins. Implications for lithium therapy

Journal of the American Chemical Society

Volumn 133, Issue 24, 2011, Pages 9506-9515

  Dudev, Todor ^a   Lim, Carmay ^a,b  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL COMPARTMENTS; BIPOLAR DISORDER; CELL MACHINERY; CELLULAR FLUID; CHARGED LIGANDS; DIVALENT CATION; HIGH CONCENTRATION; INTRIGUING QUESTIONS; KEY ENZYMES; METAL CATION; METAL CAVITIES; METAL-BINDING SITES; METALLO-PROTEINS; NET CHARGES; SOLUBLE SALTS; SOLVENT EXPOSURE;

BINDING SITES; CATALYSTS; COMPETITION; ENZYME INHIBITION; MACHINERY; METAL COMPLEXES; METALS; NEURODEGENERATIVE DISEASES; POSITIVE IONS; PROTEINS; SOLVENTS;

LITHIUM;

ASPARTIC ACID; CALCIUM ION; CARBOXYLIC ACID DERIVATIVE; DIVALENT CATION; GLUTAMINE; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM ION; MAGNESIUM ION; METAL COMPLEX; METAL ION; METALLOPROTEIN; PHOSPHATE; SOLVENT; ZINC ION; 5' NUCLEOTIDASE; CARBOXYLIC ACID; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; LIGAND; LITHIUM; MAGNESIUM;

ARTICLE; BINDING SITE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); METAL BINDING; BINDING COMPETITION; CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM; THERMODYNAMICS;

5'-NUCLEOTIDASE; BINDING, COMPETITIVE; CARBOXYLIC ACIDS; CATALYTIC DOMAIN; GLYCOGEN SYNTHASE KINASE 3; LIGANDS; LITHIUM; MAGNESIUM; METALLOPROTEINS; SOLVENTS; THERMODYNAMICS;

EID: 79959272902     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja201985s     Document Type: Article

References (71)

1. Nordlund, P.; Sjoberg, B. M.; Eklund, H. Nature 1990, 345, 593
2. Cowan, J. A. Biological Chemistry of Magnesium; VCH: New York, 1995.
3. Prasad, G. S.; Stura, E. A.; McRee, D. E.; Laco, G. S.; Hasselkus-Light, C.; Elder, J. H.; Stout, C. D. Protein Sci. 1996, 5, 2429
4. Dutzler, R.; Wang, Y. F.; Rizkallah, P.; Rosenbusch, J.; Schirmer, T. Structure 1996, 4, 127
5. Cowan, J. A. Chem. Rev. 1998, 98, 1067
6. Gilman, A. G. Annu. Rev. Biochem. 1987, 56, 615
7. Berridge, M. J.; Irvine, R. F. Nature 1989, 341, 197
8. Harwood, A. J. Cell 2001, 105, 821
9. Gould, T. D.; Quiroz, J. A.; Singh, J.; Zarate, J. C. A.; Mnji, H. K. Mol. Psychiatry 2004, 9, 734
10. Dudev, T.; Cowan, J. A.; Lim, C. J. Am. Chem. Soc. 1999, 121, 7665
11. Dudev, T.; Lim, C. Chem. Rev. 2003, 103, 773
12. Yang, T.-Y.; Dudev, T.; Lim, C. J. Am. Chem. Soc. 2008, 130, 3844
13. Berman, H. M. Acta Crystallogr. D 2002, 58, 899
14. Black, C. B.; Cowan, J. A. J. Am. Chem. Soc. 1994, 116, 1174
15. Dudev, T.; Lim, C. J. Phys. Chem. B 2004, 108, 4546
16. Dudev, T.; Lim, C. Acc. Chem. Res. 2007, 40, 85-93
17. Dudev, T.; Lin, Y. L.; Dudev, M.; Lim, C. J. Am. Chem. Soc. 2003, 125, 3168
18. Dudev, T.; Lim, C. J. Phys. Chem. B 2001, 105, 4446
19. Babu, C. S.; Dudev, T.; Casareno, R.; Cowan, J. A.; Lim, C. J. Am. Chem. Soc. 2003, 125, 9318
20. Dudev, T.; Lim, C. Annu. Rev. Biophys. 2008, 37, 97
21. Dudev, T.; Lim, C. J. Am. Chem. Soc. 2009, 113, 11754
22. Pontikis, G.; Borden, J.; Martinek, V.; Florian, J. J. Phys. Chem. A 2009, 113, 3588
23. Remko, M.; Fitz, D.; Rode, B. M. Amino Acids 2010, 39, 1309
24. Dudev, T.; Chang, L.-Y.; Lim, C. J. Am. Chem. Soc. 2005, 127, 4091
25. Rezabal, E.; Mercero, J. M.; Lopez, X.; Ugalde, J. M. J. Inorg. Biochem. 2006, 100, 374
26. Rezabal, E.; Mercero, J. M.; Lopez, X.; Ugalde, J. M. J. Inorg. Biochem. 2007, 101, 1192
27. Rezabal, E.; Mercero, J. M.; Lopez, X.; Ugalde, J. M. ChemPhysChem 2007, 8, 2119
28. Garmer, D. R.; Gresh, N. J. Am. Chem. Soc. 1994, 116, 3556
29. Dudev, T.; Lim, C. J. Phys. Chem. B 2000, 104, 3692
30. Romani, A.; Scarpa, A. Arch. Biochem. Biophys. 1992, 298, 1
31. Niki, I.; Yokokura, H.; Sudo, T.; Kato, M.; Hidaka, H. J. Biochem. 1996, 120, 685
32. Suhy, D. A.; Simon, K. D.; Linzer, D. I. H.; OHalloran, T. V. J. Biol. Chem. 1999, 274, 9183
33. MacDonald, T. L.; Martin, R. B. Trends Biochem. Sci. 1988, 13, 15
34. Collery, P.; Pirer, L.; Manfait, M.; Etienne, J. E. Alzheimers disease and dimentia syndromes consecutive to imbalanced mineral methabolisms subsequent to blood brain barrier alteration; John Libbey-Eurotext: London-Paris, 1990.
35. Marmol, F. Progr. Neuro-Psychopharmacol. Biol. Psychiatry 2008, 32, 1761
36. Shannon, R. D. Acta Crystallogr. A 1976, 32, 751
37. Friedman, H. L.; Krishnan, C. V. In Water: A comprehensive treatise; Franks, F., Ed.; Plenum Press: New York, 1973; Vol. 3, p 1.
38. Srinivasan, C.; Toon, J.; Amari, L.; Abukhdeir, A. M.; Hamm, H.; Geraldes, C. G. C.; Ho, Y.-K.; de Freitas, D. M. J. Inorg. Biochem. 2004, 98, 691
39. Ryves, W. J.; Harwood, A. J. Biochem. Biophys. Res. Commun. 2001, 280, 720
40. Ryves, W. J.; Dajani, R.; Pearl, L.; Harwood, A. J. Biochem. Biophys. Res. Commun. 2002, 290, 967
41. Leech, A. P.; Baker, G. R.; Shute, J. K.; Cohen, M. A.; Gani, D. Eur. J. Biochem. 1993, 212, 693
42. Inhorn, R. C.; Majerus, P. W. J. Biol. Chem. 1987, 262, 15946
43. Villeret, H. S.; Fromm, H. J.; Lipscomb, W. N. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 8916
44. de Freitas, D. M.; Amari, L.; Srinivasan, C.; Rong, Q.; Ramasamy, R.; Abraha, A.; Geraldes, C. F. G. C.; Boyd, M. K. Biochemistry 1994, 33, 4101
45. Jernigan, R.; Raghunathan, G.; Bahar, I. Curr. Opin. Struct. Biol. 1994, 4, 256
46. Marcus, Y. Chem Rev 1988, 88, 1475
47. Dudev, M.; Wang, J.; Dudev, T.; Lim, C. J. Phys. Chem. B 2006, 110, 1889
48. Tunell, I.; Lim, C. Inorg. Chem. 2006, 45, 4811-4819
49. Frisch, M. J. Gaussian 03; Gaussian, Inc.: Pittsburgh, PA, 2003.
50. Dudev, T.; Lim, C. J. Am. Chem. Soc. 2009, 131, 8092
51. McQuarrie, D. A. Statistical Mechanics; Harper and Row: New York, 1976.
52. Wong, M. W. Chem. Phys. Lett. 1996, 256, 391
53. Gilson, M. K.; Honig, B. H. J. Comput. Chem. 1988, 9, 327
54. Chan, S. L.; Lim, C. J. Phys. Chem. 1994, 98, 692
55. Bashford, D. In Scientific Computing in Object-Oriented Parallel Environments; Ishikawa, Y.; Oldehoeft, R. R.; Reynders, V. W.; Tholburn, M., Eds.; Springer: Berlin, 1997; Vol. 1343, p 233.
56. Dudev, T.; Lim, C. J. Am. Chem. Soc. 2006, 128, 1553
57. Brooks, B. R.; Bruccoleri, R. E.; Olafson, B. D.; States, D. J.; Swaminathan, S.; Karplus, M. J. Comput. Chem. 1983, 4, 187
58. Smith, R. M.; Martell, A. E. Sci. Total Environ. 1987, 64, 125
59. Jope, R. S. Trends Pharmacol. Sci. 2003, 24, 441
60. Kozikowski, A. P.; Gaisina, I. N.; Yuan, H.; Petukhov, P. A.; Blond, S. Y.; Fedolak, A.; Caldarone, B.; McGonigle, P. J. Am. Chem. Soc. 2007, 129, 8328
61. Aoki, M.; Yokota, T.; Sugiura, I.; Sasaki, C.; Hasegawa, T.; Okumura, C.; Ishiguro, K.; Kohno, T.; Sugio, S.; Matsuzaki, T. Acta Crystallogr. 2004, D60, 439
62. Bertrand, J. A.; Thieffine, S.; Vulpetti, A.; Cristiani, C.; Valsasina, B.; Knapp, S.; Kalisz, H. M.; Flocco, M. J. Mol. Biol. 2003, 333, 393
63. Bone, R.; Frank, L.; Springer, J. P.; Atack, J. R. Biochemistry 1994, 33, 9468
64. Johnson, K. A.; Chen, L.; Yang, H.; Roberts, M. F.; Stec, B. Biochemistry 2001, 40, 618
65. Gill, R.; Mohammed, F.; Badyal, R.; Coates, L.; Erskine, P.; Thompson, D.; Cooper, J.; Gore, M.; Wood, S. Acta Crystallogr. 2005, D61, 545
66. Li, Z.; Stieglitz, K. A.; Shrout, A. L.; Wei, Y.; Weis, R. M.; Stec, B.; Roberts, M. F. Protein Sci. 2010, 19, 309
67. Patel, S.; Martinez-Ripoll, M.; Blundell, T. L.; Albert, A. J. Mol. Biol. 2002, 320, 1087
68. Lu, S.-Y.; Jiang, Y.-J.; Zou, J.-W.; Wu, T.-X. Phys. Chem. Chem. Phys. 2011, 13, 7014
69. Sun, H.; Jiang, Y.-J.; Yu, Q.-S.; Luo, C.-C.; Zou, J.-W. J. Mol. Model. 2011, 17, 377
70. Pollack, S. J.; Knowles, M. R.; Atack, J. R.; Broughton, H. B.; Ragan, C. I.; Osborne, S.; McAllister, G. Eur. J. Biochem. 1993, 217, 281
71. Pollack, S. J.; Atack, J. R.; Knowles, M. R.; McAllister, G.; Ragan, C. I.; Baker, R.; Fletcher, S. R.; Iversen, L. L.; Broughton, H. B. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 5766