Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells

Experimental Biology and Medicine

Volumn 236, Issue 5, 2011, Pages 604-613

  Katuru, Rajasekhar ^a   Fernandes, Nicolle V ^a   Elfakhani, Manal ^a   Dutta, Dibyendu ^a   Mills, Nathaniel ^a   Hynds, Dianna L ^a   King, Clay ^a   Mo, Huanbiao ^a  

^a TEXAS WOMAN'S UNIVERSITY   (United States)

Author keywords

Apoptosis; B16 melanoma; Cell cycle; Differentiation; Geranylgeraniol; HMG CoA reductase; Mevalonate

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ACRIDINE ORANGE; ALKALINE PHOSPHATASE; CYCLIN D1; ETHIDIUM BROMIDE; GERANYLGERANIOL; MESSENGER RNA; MEVALONIC ACID;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL STRAIN 3T3; CONTROLLED STUDY; FIBROBLAST; FLUORESCENCE MICROSCOPY; GROWTH INHIBITION; IC 50; INCUBATION TIME; MELANOMA B16; MELANOMA CELL; MOUSE; NONHUMAN;

3T3-L1 CELLS; ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; DITERPENES; HUMANS; LOVASTATIN; MELANOMA, EXPERIMENTAL; MEVALONIC ACID; MICE; VITAMIN E;

MURINAE; PSIDIUM;

EID: 79958830335     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2011.010379     Document Type: Article

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