Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells

International Journal of Cancer

Volumn 71, Issue 4, 1997, Pages 691-697

  Masuda, Yutaka ^a   Yoda, Madoka ^a   Ohizumi, Hidekazu ^a   Aiuchi, Toshihiro ^a   Watabe, Masahiko ^a   Nakajo, Shigeo ^a   Nakaya, Kazuyasu ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; AMILORIDE; DIACYLGLYCEROL; GERANYLGERANIOL; ISOENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROTEIN KINASE C; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMILORIDE; ANIMALS; APOPTOSIS; DIGLYCERIDES; DITERPENES; ENZYME ACTIVATION; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; LEUKEMIA; MICE; NEOPLASM PROTEINS; PHORBOL ESTERS; PROTEIN KINASE C; STAUROSPORINE; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0030982719     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970516)71:4<691::AID-IJC29>3.0.CO;2-D     Document Type: Article

References (30)

1. + and pH. Biochem. biophys. Res. Comm., 186, 782-789 (1992).
2. BARRY, M.A., REYNOLDS, J.E. and EASTMAN, A., Etoposide-induced apoptosis in human HL60 cells is associated with intracellular acidification. Cancer Res., 53, 2349-2357 (1993).
3. BRUNK, C.F., JONES, K.C. and JAMES, T.W., Assay for nanogram quantities of DNA in cellular homogenates. Anal. Biochem., 92, 497-500 (1979).
4. DEKKER, L.V. and PARKER, P.J., Protein kinase C - a question of specificity. Trends Biochem. Sci, 19, 73-77 (1994).
5. EVAN, G.I., WYLLIE. A.H., GILBERT, C.S., LITTLEWOOD, T.D., LAND, H., BROOKS, M., WATERS, C.M., PEMM, L.Z. and HANCOCK, D.C., Induction of apoptosis in fibroblasts by c-myc protein. Cell, 69, 119-128 (1992).
6. FARNSWORTH, C.C., GELB, M.H. and GLOMSET, J.A., Identification of geranylgeranyl-modiried proteins in HeLa cells. Science, 247, 320-322 (1990).
7. HANCOCK, J.T., MAGEE, A.I., CHILDS, J.E. and MARSHALL, C.J., All ras proteins are polyisoprenylated but only some are palmitoylated. Cell, 57, 1167-1177 (1989).
8. HINCHLIFFE, J.R., Cell death in embryogenesis. In: I.D. Bowen and R.A. Lockshin (eds.): Cell death in biology and pathology. Chapman and Hall, London, 35, (1981).
9. KIKKAWA, U., MINAKUCHI, R., TARAI, Y. and NISHIZUKA, Y., Calcium activated phospholipid-dependent protein kinase (protein kinase C) from rat brain. Methods Enzymol., 99, 288-298 (1983).
10. KITTEN, G.T. and NIGG, E.A., The CaaX motif is required for isoprenylation, carboxyl methylation. and nuclear membrane association of lamin B2. J. Cell Biol., 113, 13-23 (1991).
11. MACFARLANE, D.E. and MANZEL, L., Activation of β-isoenzymes of protein kinase C (PKCβ) is necessary and sufficient for phorbol ester-induced differentiation of HL60 promyelocytes. J. biol. Chem., 269, 4327-4331 (1994).
12. MASUDA, Y., KAWAZOE, N., NAKAJO, S., YOSHIDA, T., KUROIWA, Y. and NAKAYA, K., Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells. Leukemia Res., 19, 549-556 (1995).
13. MIYASHITA, T. and REED, J.C., Bcl-2 eene transfer increases relative resistance of S49.1 and WEH17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res., 52, 5407-5411 (1992).
14. NAKAYA, K., CHOU, S., KANEKO, M. and NAKAMURA, Y, Topoisomerase inhibitors have potent differentiation-inducing activity for human and mouse myeloid leukemia cells. Jpn. J. Cancer Res., 82, 184-191 (1991).
15. OHIZUMI, H., MASUDA, Y., NAKAJO, S., SAKAI, I., OHSAWA, S. and NAKAYA, K., Geranylseranyol is a potent inducer of apoptosis in tumor cells. J. Biochem., 117, 11-13 (1995).
16. PEREZ-SALA, D., COLLADO-ESCOBAR, D. and MOLLINEDO, F., Intracellular alkalinization suppress lovastatin-induced apoptosis in HL60 cells through the inactivation of a pH-dependent endonuclease. J. biol. Chem., 270, 6235-6242 (1995).
17. + antiporter in suppression of apoptosis by aranulocyte macrophage colony-stimulating factor and interleukin-3. J. biol. Chem., 267, 9980-9987 (1992).
18. RYVES, W.J., EVANS, A.T., OLIVIER, A.R., PARKER, P.J. and EVANS, F.J., Activation of the PKC-isotypes α, β, γ, δ and ∈ by phorbol esters of different biological activities. FEBS Left., 288, 5-9 (1991).
19. SCHAFER, W.R., KIM, R., STERNE, R., THORNER, J., KIM, S.H. and RINE, J., Genetic and pharmacological suppression of oncogenic mutations in RAS genes of yeast and humans. Science, 245, 379-384 (1989).
20. SKILIEV, A.A., ZVONAREVA, N.B., ZHIVOTOVSKY, B.D. and HANSON, K.P., Determination of some nuclear deoxyribonucleases in X-irradiated rat thymocytes. Racl. Environ. Biophys., 31, 123-132 (1992).
21. SOLARY, E., BERTRAND, R., KOHN, K.W. and POMMIER, Y., Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors. Blood, 81, 1359-1368 (1993).
22. TANAKA, Y., YOSHIHARA, K., TSUYUKI, M., ITAYA-HIRONAKA, A., INADA, Y. and KAMIYA, T., Retinoic acid-specific induction of a protein kinase C isotbrm durine differentiation of HL-60 cells. J. Biochem., 111, 265-271 (1992).
23. TONETTI, D.A., HENNING-CHUBB, C., YAMANISHI, D.T. and HUBERMAN, E., Protein kinase C-β is required for macrophase differentiation of human HL-60 leukemia cells. J. biol. Chem., 269, 23230-23235 (1994).
24. TSUJIMOTO, Y., Stress-response conferred by high level of bcl-2α protein in human B lymphoblastoid cell. Oncogene, 4, 1331-1336 (1989).
25. UCKER, D.S., Cytotoxic T lymphocytes and glucocorticoids activate an endoeeneous suicide process in target cells. Nature (Lond.), 327, 62-64 (1987).
26. WATABE, M., MASUDA, Y., NAKAJO, S., YOSHIDA, T., KURIOWA, Y. and NAKAYA, K., The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells. J. biol. Chem., 271, 14067-14073 (1996).
27. WYLLIE, A.H., Glucocorticoid-induced thymocyte apoptosis is associated with endogeneous endonuclease activation. Nature (Lond.). 284, 555-556 (1980).
28. WYLLIE, A.H., KERR, J.F.R. and CURRIE, A.R., Cell death: the significance of apoptosis. Int. Rev. Cytol., 68, 251-356 (1980).
29. WYLLIE, A.H., MORRIS, R.G., SMITH, A.L. and DUNLOP, D., Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromoleculer synthesis. J. Pathol., 142, 67-77 (1984).
30. YONISH-ROUACH, E., RESNITZKY, D., LOTEM, J., SACHS, L., KIMCHI, A. and OREN, M., Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature (Lond.), 352, 345-347 (1991).