Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction- in vitro and in vivo

Experimental Biology and Medicine

Volumn 236, Issue 4, 2011, Pages 456-465

  Kiran, Sashi G ^a   Dorisetty, Raj K ^a   Umrani, Malathi R ^b   Boindala, Sesikeran ^a   Bhonde, Ramesh R ^c   Chalsani, Maniprabha ^a   Singh, Himadri ^a   Venkatesan, Vijayalakshmi ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

^b NATIONAL CENTRE FOR CELL SCIENCE   (India)

^c Stempeutics Research Malaysia Sdn Bhd   (Malaysia)

Author keywords

Cytoprotection; Free radicals; Insulin; Insulinotrophic; Islets; Pdx1; Pyridoxal 5' phosphate; Streptozotocin

Indexed keywords

AMINOOXYACETIC ACID; FREE RADICAL; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; MESSENGER RNA; PYRIDOXAL 5 PHOSPHATE; REGULATOR PROTEIN; STREPTOZOCIN; TRANSCRIPTION FACTOR PDX 1; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; IMMUNOLOCALIZATION; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION; ANIMAL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PATHOLOGY; PATHOPHYSIOLOGY; SECRETION;

MUS;

ANIMALS; BASE SEQUENCE; DIABETES MELLITUS, EXPERIMENTAL; DNA PRIMERS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; PYRIDOXAL PHOSPHATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOZOCIN;

EID: 79958819639     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2011.010361     Document Type: Article

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