Immunolocalization of nestin in pancreatic tissue of mice at different ages

World Journal of Gastroenterology

Volumn 14, Issue 46, 2008, Pages 7112-7116

  Dorisetty, Raj K ^a   Kiran, Sashi G ^a   Umrani, Malathi R ^b   Boindala, Sesikeran ^a   Bhonde, Ramesh R ^b   Venkatesan, Vijayalakshmi ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

^b NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Glucagon; Immunolocalization; Insulin; Mice; Nestin

Indexed keywords

ANTIBODY; GLUCAGON; INSULIN; NESTIN; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN;

AGE; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MALE; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; STEM CELL; TISSUE SECTION; AGING; ANIMAL; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NEWBORN;

AGING; ANIMALS; ANIMALS, NEWBORN; GLUCAGON; IMMUNOHISTOCHEMISTRY; INSULIN; INTERMEDIATE FILAMENT PROTEINS; MALE; MICE; NERVE TISSUE PROTEINS; PANCREAS;

EID: 63449123864     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.7112     Document Type: Article

References (30)

1. Lohr M, Kloppel G. Residual insulin positivity and pancreatic atrophy in relation to duration of chronic type 1 (insulin-dependent) diabetes mellitus and microangiopathy. Diabetologia 1987; 30: 757-762
2. Pipeleers D, Ling Z. Pancreatic beta cells in insulin-dependent diabetes. Diabetes Metab Rev 1992; 8: 209-227
3. DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome respons ible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991; 14: 173-194
4. Kruszynska YT, Olefsky JM. Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus. J Investig Med 1996; 44: 413-428
5. Brownlee M, Cerami A. The biochemistry of the complications of diabetes mellitus. Annu Rev Biochem 1981; 50: 385-432
6. Okuno M, Minami K, Okumachi A, Miyawaki K, Yokoi N, Toyokuni S, Seino S. Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes. Am J Physiol Endocrinol Metab 2007; 292: E158-E165
7. Bonner-Weir S, Taneja M, Weir GC, Tatarkiewicz K, Song KH, Sharma A, O'Neil JJ. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci USA 2000; 97: 7999-8004
8. Choi Y, Ta M, Atouf F, Lumelsky N. Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny. Stem Cells 2004; 22: 1070-1084
9. Agarwal SS. Regulating stem cell research & therapy. Indian J Med Res 2006; 124: 225-228
10. Walcott JC, Provis JM. Muller cells express the neuronal progenitor cell marker nestin in both differentiated and undifferentiated human foetal retina. Clin Experiment Ophthalmol 2003; 31: 246-249
11. Messam CA, Hou J, Berman JW, Major EO. Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells. Brain Res Dev Brain Res 2002; 134: 87-92
12. Lendahl U, Zimmerman LB, McKay RD. CNS stem cells express a new class of intermediate filament protein. Cell 1990; 60: 585-595
13. Dahlstrand J, Zimmerman LB, McKay RD, Lendahl U. Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments. J Cell Sci 1992; 103 (Pt 2): 589-597
14. Wislet-Gendebien S, Hans G, Leprince P, Rigo JM, Moonen G, Rogister B. Plasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron-like phenotype. Stem Cells 2005; 23: 392-402
15. Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 2002; 143: 3152-3161
16. Huang H, Tang X. Phenotypic determination and characterization of nestin-positive precursors derived from human fetal pancreas. Lab Invest 2003; 83: 539-547
17. Hunziker E, Stein M. Nestin-expressing cells in the pancreatic islets of Langerhans. Biochem Biophys Res Commun 2000; 271: 116-119
18. Humphrey RK, Bucay N, Beattie GM, Lopez A, Messam CA, Cirulli V, Hayek A. Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas. Diabetes 2003; 52: 2519-2525
19. Zulewski H, Abraham EJ, Gerlach MJ, Daniel PB, Moritz W, Muller B, Vallejo M, Thomas MK, Habener JF. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 2001; 50: 521-533
20. Piper K, Ball SG, Turnpenny LW, Brickwood S, Wilson DI, Hanley NA. Beta-cell differentiation during human development does not rely on nestin-positive precursors: implications for stem cell-derived replacement therapy. Diabetologia 2002; 45: 1045-1047
21. Selander L, Edlund H. Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech Dev 2002; 113: 189-192
22. Street CN, Lakey JR, Seeberger K, Helms L, Rajotte RV, Shapiro AM, Korbutt GS. Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker. J Endocrinol 2004; 180: 213-225
23. Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001; 292: 1389-1394
24. Fukayama M, Ogawa M, Hayashi Y, Koike M. Development of human pancreas. Immunohistochemical study of fetal pancreatic secretory proteins. Differentiation 1986; 31: 127-133
25. Erlandsen SL, Hegre OD, Parsons JA, McEvoy RC, Elde RP. Pancreatic islet cell hormones distribution of cell types in the islet and evidence for the presence of somatostatin and gastrin within the D cell. J Histochem Cytochem 1976; 24: 883-897
26. Dahlstrand J, Collins VP, Lendahl U. Expression of the class VI intermediate filament nestin in human central nervous system tumors. Cancer Res 1992; 52: 5334-5341
27. Palm K, Salin-Nordstrom T, Levesque MF, Neuman T. Fetal and adult human CNS stem cells have similar molecular characteristics and developmental potential. Brain Res Mol Brain Res 2000; 78: 192-195
28. Rietze RL, Valcanis H, Brooker GF, Thomas T, Voss AK, Bartlett PF. Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 2001; 412: 736-739
29. Wang R, Li J, Yashpal N, Gao N. Nestin expression and clonal analysis of islet-derived epithelial monolayers: insight into nestin-expressing cell heterogeneity and differentiation potential. J Endocrinol 2005; 184: 329-339
30. Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001; 292: 1389-1394