FKBPs: At the crossroads of folding and transduction

Trends in Plant Science

Volumn 6, Issue 9, 2001, Pages 426-431

  Harrar, Yaël ^a   Bellini, Catherine ^a   Faure, Jean Denis ^a  

^a CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALMODULIN; FK 506 BINDING PROTEIN; FUNGAL PROTEIN; MEMBRANE PROTEIN; PAS1 PROTEIN, FUNGAL;

ANIMAL; APOPTOSIS; ARABIDOPSIS; CELL CYCLE; CLASSIFICATION; COMPARATIVE STUDY; GENETICS; HUMAN; METABOLISM; PHYLOGENY; PHYSIOLOGY; PLANT PHYSIOLOGY; PROTEIN FOLDING; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; APOPTOSIS; ARABIDOPSIS; CALMODULIN; CELL CYCLE; FUNGAL PROTEINS; HUMANS; MEMBRANE PROTEINS; PHYLOGENY; PLANT PHYSIOLOGY; PROTEIN FOLDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TACROLIMUS BINDING PROTEINS;

EID: 0035209361     PISSN: 13601385     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1360-1385(01)02044-1     Document Type: Review

References (41)

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3. Sequence diversification of the FK506-binding proteins in several different genomes
4. Immunophilins in animals and higher plants
5. Chemistry and biology of the immunophilins and their immunosuppressive ligands
6. FK506, an immunosuppressant targeting calcineurin function
7. The target of rapamycin (TOR) proteins
8. Immunophilin ligands as a novel treatment of neurological disorders
9. 2+-binding ability
10. Mechanism of TGFβ receptor inhibition by FKBP12
11. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein
12. FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain
13. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
14. 2+ release channels (ryanodine receptors)
15. All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae
16. Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
17. The immunophilin FKBP12 functions as a common inhibitor of the TGFβ family type I receptors
18. Chaperone function of Hsp90-associated proteins
19. FKBP54, a novel FK506-binding protein in avian progesterone receptor complexes and HeLa extracts
20. Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes
21. The 59 kDa FK506-binding protein, a 90 kDa heat shock protein binding immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus
22. Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein
23. Rabbit FKBP59-heat shock protein binding immunophilin (HBI) is a calmodulin binding protein
24. FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin
25. Immunophilins, Refsum disease, and lupus nephritis: The peroxisomal enzyme phytanoyl-COA α-hydroxylase is a new FKBP-associated protein
26. Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52
27. Molecular characterization of a FKBP-type immunophilin from higher plants
28. A novel plant peptidyl-prolyl cis-trans-isomerase (PPiase): cDNA cloning, structural analysis, enzymatic activity and expression
29. Novel structure of a high molecular weight FK506 binding protein from Arabidopsis thaliana
30. Mutation in the Arabidopsis PASTICCINO 1 gene, which encodes a new FK506-binding protein-like protein, has a dramatic effect on plant development
31. A maize FK506-sensitive immunophilin, mzFKBP-66, is a peptidylproline cis-trans-isomerase that interacts with calmodulin and a 36-kDa cytoplasmic protein
32. The wheat peptidyl prolyl cis-trans-isomerase FKBP77 is heat induced and developmentally regulated
33. Binding of immunophilins to the 90 kDa heat shock protein (hsp90) via a tetratricopeptide repeat domain is a conserved protein interaction in plants
34. High-molecular-weight FK506-binding proteins are components of heat-shock protein 90 heterocomplexes in wheat germ lysate
35. Molecular characterization of a plant FKBP12 that does not mediate action of FK506 and rapamycin
36. An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506
37. The PASTICCINO genes of Arabidopsis thaliana are involved in the control of cell division and differentiation
38. FK506 and the role of immunophilins in nerve regeneration
39. Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506
40. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
41. Molecular cloning and overexpression of the human FK506-binding protein FKBP