Mechanisms of cell polarity and aquaporin sorting in the nephron

Pflugers Archiv European Journal of Physiology

Volumn 461, Issue 6, 2011, Pages 607-621

  Edemir, Bayram ^a   Pavenstädt, Hermann ^a   Schlatter, Eberhard ^a   Weide, Thomas ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Aquaporins; Diabetes insipidus; Kidney; Transport; Vasopressin

Indexed keywords

AQUAPORIN; AQUAPORIN 1; AQUAPORIN 2; AQUAPORIN 3; AQUAPORIN 4; AQUAPORIN 5; AQUAPORIN 6; AQUAPORIN 7; AQUAPORIN 8; AQUAPORIN 9; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; EZRIN; GLYCOGEN SYNTHASE KINASE 3BETA; GUANOSINE TRIPHOSPHATE; MEMBRANE ASSOCIATED GUANYLATE CYCLASE KINASE; MOESIN; MYOSIN; PDZ PROTEIN; PROTEIN CDC42; PROTEIN KINASE C; PROTEIN ZO1; RAB PROTEIN; RAB11 PROTEIN; RADIXIN; SNARE PROTEIN; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN 4;

AMINO TERMINAL SEQUENCE; APICAL MEMBRANE; BINDING SITE; CELL POLARITY; CELL SELECTION; CYTOSKELETON; ENDOCYTOSIS; EXOCYTOSIS; HUMAN; IMMUNOPRECIPITATION; INTRACELLULAR TRANSPORT; KIDNEY EPITHELIUM; MEMBRANE VESICLE; NEPHRON; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; UBIQUITINATION;

ANIMALS; AQUAPORINS; CELL POLARITY; EPITHELIAL CELLS; EYE PROTEINS; HUMANS; MEMBRANE PROTEINS; NEPHRONS; NERVE TISSUE PROTEINS; NUCLEOSIDE-PHOSPHATE KINASE;

EID: 79958801883     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-0928-3     Document Type: Review

References (152)

1. M Adachi Y Hamazaki Y Kobayashi M Itoh S Tsukita M Furuse S Tsukita 2009 Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins Mol Cell Biol 29 2372 2389 19255144 1:CAS:528:DC%2BD1MXlt1Ortbk%3D
2. E Alpi E Landi M Barilari M Serresi P Salvadori A Bachi L Dente 2009 Channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics Biochem J 419 289 300 19138174 1:CAS:528: DC%2BD1MXjs1ynt7s%3D
3. N Anzai E Deval L Schaefer V Friend M Lazdunski E Lingueglia 2002 The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons J Biol Chem 277 16655 16661 11872753 1:CAS:528:DC%2BD38XjslWhtro%3D (Pubitemid 34967684)
4. E Assemat E Bazellieres E Pallesi-Pocachard BA Le D Massey-Harroche 2008 Polarity complex proteins Biochim Biophys Acta 1778 614 630 18005931 1:CAS:528:DC%2BD1cXjtVSqt7w%3D (Pubitemid 351317801)
5. Z Balklava S Pant H Fares BD Grant 2007 Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic Nat Cell Biol 9 1066 1073 17704769 1:CAS:528:DC%2BD2sXpslGjurc%3D (Pubitemid 47338145)
6. M Barile T Pisitkun MJ Yu CL Chou MJ Verbalis RF Shen MA Knepper 2005 Large scale protein identification in intracellular aquaporin-2 vesicles from renal inner medullary collecting duct Mol Cell Proteomics 4 1095 1106 15905145 1:CAS:528:DC%2BD2MXpsFals7k%3D (Pubitemid 41223369)
7. C Becamel S Gavarini B Chanrion G Alonso N Galeotti A Dumuis J Bockaert P Marin 2004 The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins J Biol Chem 279 20257 20266 14988405 1:CAS:528: DC%2BD2cXjs1Whur0%3D (Pubitemid 38623471)
8. E Beitz K Liu M Ikeda WB Guggino P Agre M Yasui 2006 Determinants of AQP6 trafficking to intracellular sites versus the plasma membrane in transfected mammalian cells Biol Cell 98 101 109 15892693 1:CAS:528:DC%2BD28XmtlOkuw%3D%3D (Pubitemid 43230620)
9. M Boone P Deen 2008 Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Pflügers Archiv Eur J Physiol 456 1005 1024 1:CAS:528:DC%2BD1cXhtVSiurbP
10. DM Bryant A Datta AE Rodriguez-Fraticelli J Peranen F Martin-Belmonte KE Mostov 2010 A molecular network for de novo generation of the apical surface and lumen Nat Cell Biol 12 1035 1045 20890297 1:CAS:528:DC%2BC3cXhtlKgs7bI
11. K Campbell E Knust H Skaer 2009 Crumbs stabilises epithelial polarity during tissue remodelling J Cell Sci 122 2604 2612 19567473 1:CAS:528: DC%2BD1MXhtVGhsL%2FO
12. PF Colosimo X Liu NA Kaplan NS Tolwinski 2010 GSK3+| affects apicalΓÇôbasal polarity and cellΓÇôcell adhesion by regulating aPKC levels Dev Dyn 239 115 125 19422025 1:CAS:528:DC%2BC3cXhsFCktr4%3D
13. MT Conner AC Conner JEP Brown RM Bill 2010 Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity Biochemistry 49 821 823 20063900 1:CAS:528:DC%2BC3cXlvFWntw%3D%3D
14. MF De PJ Savelkoul EJ Kamsteeg IB Konings P van der Sluijs R Mallmann A Oksche PM Deen 2005 Lack of arginine vasopressin-induced phosphorylation of aquaporin-2 mutant AQP2-R254L explains dominant nephrogenic diabetes insipidus J Am Soc Nephrol 16 2872 2880 (Pubitemid 44743484)
15. A Djiane S Yogev M Mlodzik 2005 The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye Cell 121 621 631 15907474 1:CAS:528:DC%2BD2MXkslelsLg%3D (Pubitemid 40720014)
16. K Duning EM Schurek M Schluter M Bayer HC Reinhardt A Schwab L Schaefer T Benzing B Schermer MA Saleem TB Huber, et al. 2008 KIBRA modulates directional migration of podocytes J Am Soc Nephrol 19 1891 1903 18596123 1:CAS:528:DC%2BD1cXht1Cls7zF
17. ML Elkjar LN Nejsum V Gresz TH Kwon UB Jensen J Frokiar S Nielsen 2001 Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways Am J Physiol Ren Physiol 281 F1047 F1057
18. A Engel Y Fujiyoshi T Gonen T Walz 2008 Junction-forming aquaporins Curr Opin Struct Biol 18 229 235 18194855 1:CAS:528:DC%2BD1cXkvFCls7c%3D
19. M Ernkvist PN Luna S Audebert P Lecine I Sinha M Liu M Schlueter A Horowitz K Aase T Weide JP Borg, et al. 2009 The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells Blood 113 244 253 18824598 1:CAS:528:DC%2BD1MXmtFSqtA%3D%3D
20. S Etienne-Manneville 2008 Polarity proteins in migration and invasion Oncogene 27 6970 6980 19029938 1:CAS:528:DC%2BD1cXhsVWhurbJ
21. K Eto Y Noda S Horikawa S Uchida S Sasaki 2010 Phosphorylation of aquaporin-2 regulates its water permeability J Biol Chem 285 40777 40784 20971851 1:CAS:528:DC%2BC3cXhsFynsLnO
22. S Fan V Fogg Q Wang XW Chen CJ Liu B Margolis 2007 A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions J Cell Biol 178 387 398 17646395 1:CAS:528:DC%2BD2sXos1Crs7Y%3D (Pubitemid 47196148)
23. RA Fenton HB Moeller JD Hoffert MJ Yu S Nielsen MA Knepper 2008 Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressin Proc Natl Acad Sci U S A 105 3134 3139 18287043 1:CAS:528:DC%2BD1cXjtVShur4%3D (Pubitemid 351723680)
24. AB Fielding E Schonteich J Matheson G Wilson X Yu GR Hickson S Srivastava SA Baldwin R Prekeris GW Gould 2005 Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis EMBO J 24 3389 3399 16148947 1:CAS:528:DC%2BD2MXhtVKns7%2FE (Pubitemid 41486777)
25. M Fliegauf T Benzing H Omran 2007 When cilia go bad: cilia defects and ciliopathies Nat Rev Mol Cell Biol 8 880 893 17955020 1:CAS:528: DC%2BD2sXhtF2qsLzI (Pubitemid 47622564)
26. TM Fujiwara DG Bichet 2005 Molecular biology of hereditary diabetes insipidus J Am Soc Nephrol 16 2836 2846 16093448 1:CAS:528:DC%2BD2MXhtFegtLjP (Pubitemid 44743480)
27. H Funaki T Yamamoto Y Koyama D Kondo E Yaoita K Kawasaki H Kobayashi S Sawaguchi H Abe I Kihara 1998 Localization and expression of AQP5 in cornea, serous salivary glands, and pulmonary epithelial cells Am J Physiol 275 C1151 C1157 9755069 1:CAS:528:DyaK1cXmsl2ju7w%3D
28. F Garcia A Kierbel MC Larocca SA Gradilone P Splinter NF LaRusso RA Marinelli 2001 The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP J Biol Chem 276 12147 12152 11278499 1:CAS:528:DC%2BD3MXjtFyltLs%3D
29. NJ Godde RC Galea IA Elsum PO Humbert 2010 Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions J Mammary Gland Biol Neoplasia 15 149 168 20461450
30. MR Golachowska D Hoekstra SC van IJzendoorn 2010 Recycling endosomes in apical plasma membrane domain formation and epithelial cell polarity Trends Cell Biol 20 618 626 20833047 1:CAS:528:DC%2BC3cXht1WlsLzI
31. I Gosens AI den Hollander FP Cremers R Roepman 2008 Composition and function of the Crumbs protein complex in the mammalian retina Exp Eye Res 86 713 726 18407265 1:CAS:528:DC%2BD1cXlslyls7k%3D
32. I Gosens A Sessa AI den Hollander SJ Letteboer V Belloni ML Arends BA Le FP Cremers V Broccoli R Roepman 2007 FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex Exp Cell Res 313 3959 3970 17920587 1:CAS:528:DC%2BD2sXht1alsrrL (Pubitemid 350001292)
33. JP Grunfeld BC Rossier 2009 Lithium nephrotoxicity revisited Nat Rev Nephrol 5 270 276 19384328 1:CAS:528:DC%2BD1MXkvVSqsbY%3D
34. FA Grusche HE Richardson KF Harvey 2010 Upstream regulation of the hippo size control pathway Curr Biol 20 R574 R582 20619814 1:CAS:528: DC%2BC3cXoslajtb4%3D
35. XG Guan WH Su F Yi D Zhang F Hao HG Zhang YJ Liu XC Feng TH Ma 2010 NPA motifs play a key role in plasma membrane targeting of aquaporin-4 IUBMB Life 62 222 226 20186918 1:CAS:528:DC%2BC3cXktVCktrg%3D
36. M Hara-Chikuma AS Verkman 2005 Aquaporin-3 functions as a glycerol transporter in mammalian skin Biol Cell 97 479 486 15966863 1:CAS:528: DC%2BD2MXovV2mtbw%3D (Pubitemid 40936590)
37. M Hara-Chikuma AS Verkman 2008 Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption Mol Cell Biol 28 326 332 17967887 1:CAS:528:DC%2BD1cXktVaktQ%3D%3D
38. B Heller E du-Gyamfi W Smith-Kinnaman C Babbey M Vora Y Xue R Bittman RV Stahelin CD Wells 2010 Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain J Biol Chem 285 12308 12320 20080965 1:CAS:528:DC%2BC3cXksVGkt7s%3D
39. V Henn B Edemir E Stefan B Wiesner D Lorenz F Theilig R Schmitt L Vossebein G Tamma M Beyermann E Krause, et al. 2004 Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells J Biol Chem 279 26654 26665 15037626 1:CAS:528:DC%2BD2cXkvVWgtLw%3D (Pubitemid 38798823)
40. JD Hoffert RA Fenton HB Moeller B Simons D Tchapyjnikov BW McDill MJ Yu T Pisitkun F Chen MA Knepper 2008 Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2 J Biol Chem 283 24617 24627 18606813 1:CAS:528:DC%2BD1cXhtVGktbrI
41. JD Hoffert T Pisitkun G Wang RF Shen MA Knepper 2006 Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites Proc Natl Acad Sci U S A 103 7159 7164 16641100 1:CAS:528:DC%2BD28XkslCktLc%3D
42. TW Hurd L Gao MH Roh IG Macara B Margolis 2003 Direct interaction of two polarity complexes implicated in epithelial tight junction assembly Nat Cell Biol 5 137 142 12545177 1:CAS:528:DC%2BD3sXot12quw%3D%3D (Pubitemid 36210848)
43. M Ikeda E Beitz D Kozono WB Guggino P Agre M Yasui 2002 Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63 J Biol Chem 277 39873 39879 12177001 1:CAS:528:DC%2BD38XnvVehs7w%3D (Pubitemid 35190973)
44. NB Illarionova E Gunnarson Y Li H Brismar A Bondar S Zelenin A Aperia 2010 Functional and molecular interactions between aquaporins and Na, K-ATPase Neuroscience 168 915 925 19962432 1:CAS:528:DC%2BC3cXntlahu7w%3D
45. T Inoue S Nielsen B Mandon J Terris BK Kishore MA Knepper 1998 SNAP-23 in rat kidney: colocalization with aquaporin-2 in collecting duct vesicles Am J Physiol 275 F752 F760 9815132 1:CAS:528:DyaK1cXnsF2ktLk%3D
46. K Ishibashi S Hara S Kondo 2009 Aquaporin water channels in mammals Clin Exp Nephrol 13 107 117 19085041 1:CAS:528:DC%2BD1MXmt1Wltbg%3D
47. K Ishibashi M Imai S Sasaki 2000 Cellular localization of aquaporin 7 in the rat kidney Exp Nephrol 8 252 257 10940724 1:CAS:528:DC%2BD3cXmsl2qt78%3D (Pubitemid 30665896)
48. AM Jensen M Westerfield 2004 Zebrafish mosaic eyes is a novel FERM protein required for retinal lamination and retinal pigmented epithelial tight junction formation Curr Biol 14 711 717 15084287 1:CAS:528:DC%2BD2cXjt1Cmsbc%3D (Pubitemid 38503609)
49. G Joberty C Petersen L Gao IG Macara 2000 The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 Nat Cell Biol 2 531 539 10934474 1:CAS:528:DC%2BD3cXlslymt7Y%3D
50. E Kamberov O Makarova M Roh A Liu D Karnak S Straight B Margolis 2000 Molecular cloning and characterization of Pals, proteins associated with mLin-7 J Biol Chem 275 11425 11431 10753959 1:CAS:528:DC%2BD3cXislShu7k%3D (Pubitemid 30212796)
51. EJ Kamsteeg PJ Savelkoul G Hendriks IB Konings NM Nivillac AK Lagendijk P van der Sluijs PM Deen 2008 Missorting of the aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is due to the loss of E258 Pflugers Arch 455 1041 1054 17965877 1:CAS:528:DC%2BD1cXhtFWktLY%3D (Pubitemid 351169981)
52. EJ Kamsteeg TA Wormhoudt JP Rijss CH van Os PM Deen 1999 An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus EMBO J 18 2394 2400 10228154 1:CAS:528:DyaK1MXjtlKhs74%3D (Pubitemid 29213273)
53. EJ Kamsteeg AS Duffield IBM Konings J Spencer P Pagel PMT Deen MJ Caplan 2007 MAL decreases the internalization of the aquaporin-2 water channel PNAS 104 16696 16701 17940053 1:CAS:528:DC%2BD2sXht1Wmu73E (Pubitemid 350211079)
54. T Katsura CE Gustafson DA Ausiello D Brown 1997 Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells Am J Physiol 272 F817 F822 9227644 1:STN:280:DyaK2szntFCiuw%3D%3D
55. JD Kawedia ML Nieman GP Boivin JE Melvin KI Kikuchi AR Hand JN Lorenz AG Menon 2007 Interaction between transcellular and paracellular water transport pathways through aquaporin 5 and the tight junction complex PNAS 104 3621 3626 17360692 1:CAS:528:DC%2BD2sXjtVWku78%3D (Pubitemid 46364208)
56. KJ Kemphues JR Priess DG Morton NS Cheng 1988 Identification of genes required for cytoplasmic localization in early C. elegans embryos Cell 52 311 320 3345562 1:CAS:528:DyaL1cXhvVeqtr0%3D
57. M Kim A Datta P Brakeman W Yu KE Mostov 2007 Polarity proteins PAR6 and aPKC regulate cell death through GSK-3beta in 3D epithelial morphogenesis J Cell Sci 120 2309 2317 17606986 1:CAS:528:DC%2BD2sXpslChsL8%3D (Pubitemid 47225934)
58. J Klokkers P Langehanenberg B Kemper S Kosmeier BG von C Riethmuller F Wunder A Sindic H Pavenstadt E Schlatter B Edemir 2009 Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells Am J Physiol Ren Physiol 297 F693 F703 1:CAS:528:DC%2BD1MXhtFGrur%2FO
59. E Klussmann K Maric B Wiesner M Beyermann W Rosenthal 1999 Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells J Biol Chem 274 4934 4938 9988736 1:CAS:528:DyaK1MXhsFSls7Y%3D
60. C Kosugi-Tanaka X Li C Yao T Akamatsu N Kanamori K Hosoi 2006 Protein kinase A-regulated membrane trafficking of a green fluorescent protein-aquaporin 5 chimera in MDCK cells Biochim Biophys Acta BBA Mol Cell Res 1763 337 344 1:CAS:528:DC%2BD28XksFOqtbw%3D
61. C Kurschner PG Mermelstein WT Holden DJ Surmeier 1998 CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins Mol Cell Neurosci 11 161 172 9647694 1:CAS:528:DyaK1cXksV2msrY%3D (Pubitemid 28298387)
62. M Kuwahara K Iwai T Ooeda T Igarashi E Ogawa Y Katsushima I Shinbo S Uchida Y Terada MF Arthus M Lonergan, et al. 2001 Three families with autosomal dominant nephrogenic diabetes insipidus caused by aquaporin-2 mutations in the C-terminus Am J Hum Genet 69 738 748 11536078 1:CAS:528:DC%2BD3MXnslKmsbg%3D (Pubitemid 32868519)
63. U Laforenza G Gastaldi M Grazioli E Cova S Tritto A Faelli G Calamita U Ventura 2005 Expression and immunolocalization of aquaporin-7 in rat gastrointestinal tract Biol Cell 97 605 613 15943587 1:CAS:528: DC%2BD2MXmsFCiu7o%3D (Pubitemid 41079033)
64. P Laprise S Beronja NF Silva-Gagliardi M Pellikka AM Jensen CJ McGlade U Tepass 2006 The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size Dev Cell 11 363 374 16950127 1:CAS:528:DC%2BD28XpslWqt74%3D (Pubitemid 44283938)
65. C Lemmers E Medina MH Delgrossi D Michel JP Arsanto BA Le 2002 hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells J Biol Chem 277 25408 25415 11964389 1:CAS:528:DC%2BD38XlsVWhs7w%3D (Pubitemid 34951853)
66. C Lemmers D Michel L Lane-Guermonprez MH Delgrossi E Medina JP Arsanto BA Le 2004 CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells Mol Biol Cell 15 1324 1333 14718572 1:CAS:528:DC%2BD2cXitlGgs7s%3D (Pubitemid 38316238)
67. Z Li L Wang TS Hays Y Cai 2008 Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity J Cell Biol 180 31 38 18195099 1:CAS:528:DC%2BD1cXnsFymtw%3D%3D
68. DC Lu H Zhang Z Zador AS Verkman 2008 Impaired olfaction in mice lacking aquaporin-4 water channels FASEB J 22 3216 3223 18511552 1:CAS:528: DC%2BD1cXhtV2rurvM
69. H Lu TX Sun R Bouley K Blackburn M McLaughlin D Brown 2004 Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2 Am J Physiol Ren Physiol 286 F233 F243 1:CAS:528: DC%2BD2cXhsFKqsrc%3D
70. HAJ Lu TX Sun T Matsuzaki XH Yi J Eswara R Bouley M McKee D Brown 2007 Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking J Biol Chem 282 28721 28732 17636261 1:CAS:528:DC%2BD2sXhtVOmtbrN (Pubitemid 47606045)
71. HJ Lu T Matsuzaki R Bouley U Hasler QH Qin D Brown 2008 The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells Am J Physiol Ren Physiol 295 F290 F294 1:CAS:528:DC%2BD1cXoslynu7s%3D
72. T Ma B Yang MA Matthay AS Verkman 1998 Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels Am J Respir Cell Mol Biol 19 143 149 9651190 1:CAS:528:DyaK1cXks1SktL4%3D (Pubitemid 128354951)
73. IG Macara 2004 Parsing the polarity code Nat Rev Mol Cell Biol 5 220 231 14991002 1:CAS:528:DC%2BD2cXhs1Clt7Y%3D
74. R Madrid S Le Maout MB Barrault K Janvier S Benichou J Merot 2001 Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes EMBO J 20 7008 7021 11742978 1:CAS:528:DC%2BD38XpsFKr (Pubitemid 34062293)
75. O Makarova MH Roh CJ Liu S Laurinec B Margolis 2003 Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1) Gene 302 21 29 12527193 1:CAS:528:DC%2BD3sXis1arsQ%3D%3D (Pubitemid 36078394)
76. M Marazuela MA Alonso 2004 Expression of MAL and MAL2, two elements of the protein machinery for raft-mediated transport, in normal and neoplastic human tissue Histol Histopathol 19 925 933 15168355 1:CAS:528: DC%2BD2cXntVyguro%3D (Pubitemid 38855073)
77. D Marples B Barber A Taylor 1996 Effect of a dynein inhibitor on vasopressin action in toad urinary bladder J Physiol 490 767 774 8683474 1:CAS:528:DyaK28XhtFSjsrw%3D (Pubitemid 26058846)
78. D Marples TA Schroer N Ahrens A Taylor MA Knepper S Nielsen 1998 Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct Am J Physiol Ren Physiol 274 F384 F394 1:CAS:528:DyaK1cXht1CksLc%3D
79. S Massari C Perego V Padovano A DÇÖAmico A Raimondi M Francolini G Pietrini 2009 LIN7 mediates the recruitment of IRSp53 to tight junctions Traffic 10 246 257 19054385 1:CAS:528:DC%2BD1MXhvFGhtL4%3D
80. H McNeill 2009 Planar cell polarity and the kidney J Am Soc Nephrol 20 2104 2111 19762494 1:CAS:528:DC%2BD1MXhtlSrsbbP
81. AC Mistry R Mallick JD Klein T Weimbs JM Sands O Frohlich 2009 Syntaxin specificity of aquaporins in the inner medullary collecting duct Am J Physiol Ren Physiol 297 F292 F300 1:CAS:528:DC%2BD1MXhtVaht73J
82. HB Moeller MA Knepper RA Fenton 2009 Serine 269 phosphorylated aquaporin-2 is targeted to the apical membrane of collecting duct principal cells Kidney Int 75 295 303 18843259 1:CAS:528:DC%2BD1MXlvFCmsA%3D%3D
83. HB Moeller N Macaulay MA Knepper RA Fenton 2009 Role of multiple phosphorylation sites in the COOH-terminal tail of aquaporin-2 for water transport: evidence against channel gating Am J Physiol Ren Physiol 296 F649 F657 1:CAS:528:DC%2BD1MXjtFGrs70%3D
84. E Monzani R Bazzotti C Perego CAM La Porta 2009 AQP1 is not only a water channel: it contributes to cell migration through Lin7/Beta-Catenin PLoS ONE 4 e6167 19584911
85. SM Mulders AJ van der Kemp SA Terlouw HAF van Boxtel CH van Os PMT Deen 1998 The exchange of functional domains among aquaporins with different transport characteristics Pflugers Arch 436 599 607 9683734 1:CAS:528: DC%2BD3cXhsFajs7o%3D (Pubitemid 28414724)
86. K Nagai M Watanabe M Seto A Hisatsune T Miyata Y Isohama 2007 Nitric oxide decreases cell surface expression of aquaporin-5 and membrane water permeability in lung epithelial cells Biochem Biophys Res Commun 354 579 584 17250805 1:CAS:528:DC%2BD2sXhtlOgtLc%3D (Pubitemid 46161363)
87. Nedvetsky PI, Tamma G, Beulshausen S, Valenti G, Rosenthal W, Klussmann E (2009) Regulation of aquaporin-2 trafficking. Handb Exp Pharmacol (190):133-157
88. PI Nedvetsky E Stefan S Frische K Santamaria B Wiesner G Valenti JA Hammer S Nielsen JR Goldenring W Rosenthal E Klussmann 2007 A role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle Traffic 8 110 123 17156409 1:CAS:528:DC%2BD2sXhslGktLc%3D (Pubitemid 46099998)
89. PI Nedvetsky V Tabor G Tamma S Beulshausen P Skroblin A Kirschner K Mutig M Boltzen O Petrucci A Vossenkämper B Wiesner, et al. 2010 Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase J Am Soc Nephrol 21 1645 1656 20724536 1:CAS:528: DC%2BC3cXhtlems7%2FL
90. LN Nejsum WJ Nelson 2007 A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity J Cell Biol 178 323 335 17635938 1:CAS:528:DC%2BD2sXnvFCksL0%3D (Pubitemid 47076467)
91. S Nielsen CL Chou D Marples EI Christensen BK Kishore MA Knepper 1995 Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane Proc Natl Acad Sci U S A 92 1013 1017 7532304 1:CAS:528:DyaK2MXjslehu7o%3D
92. S Nielsen SR DiGiovanni EI Christensen MA Knepper HW Harris 1993 Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney PNAS 90 11663 11667 8265605 1:CAS:528:DyaK2cXntl2rsw%3D%3D (Pubitemid 24008699)
93. S Nielsen J Frøkiaer D Marples TH Kwon P Agre MA Knepper 2002 Aquaporins in the kidney: from molecules to medicine Physiol Rev 82 205 244 11773613 1:CAS:528:DC%2BD38XovFSitw%3D%3D (Pubitemid 34654219)
94. S Nielsen TH Kwon BM Christensen D Promeneur J FrokiAEr D Marples 1999 Physiology and pathophysiology of renal aquaporins J Am Soc Nephrol 10 647 663 10073616 1:CAS:528:DyaK1MXhsl2jtb4%3D (Pubitemid 29117647)
95. S Nielsen D Marples H Birn M Mohtashami NO Dalby M Trimble M Knepper 1995 Expression of VAMP-2-like protein in kidney collecting duct intracellular vesicles. Colocalization with aquaporin-2 water channels J Clin Invest 96 1834 1844 7560075 1:CAS:528:DyaK2MXosFyhtr0%3D
96. S Nielsen T Pallone BL Smith EI Christensen P Agre AB Maunsbach 1995 Aquaporin-1 water channels in short and long loop descending thin limbs and in descending vasa recta in rat kidney Am J Physiol 268 F1023 F1037 7541952 1:CAS:528:DyaK2MXmvVOqu7g%3D
97. S Nielsen BL Smith EI Christensen MA Knepper P Agre 1993 CHIP28 water channels are localized in constitutively water-permeable segments of the nephron J Cell Biol 120 371 383 7678419 1:CAS:528:DyaK3sXpvVKmsA%3D%3D (Pubitemid 23040077)
98. S Nielsen J Frokiar D Marples TH Kwon P Agre MA Knepper 2002 Aquaporins in the kidney: from molecules to medicine Physiol Rev 82 205 244 11773613 1:CAS:528:DC%2BD38XovFSitw%3D%3D (Pubitemid 34654219)
99. Y Noda S Sasaki 2005 Trafficking mechanism of water channel aquaporin-2 Biol Cell 97 885 892 16293109 1:CAS:528:DC%2BD2MXht1Crtb7E (Pubitemid 41819306)
100. Y Noda E Sohara E Ohta S Sasaki 2010 Aquaporins in kidney pathophysiology Nat Rev Nephrol 6 168 178 20101255 1:CAS:528:DC%2BC3cXisValtbo%3D
101. Y Noda S Horikawa E Kanda M Yamashita H Meng K Eto Y Li M Kuwahara K Hirai C Pack M Kinjo, et al. 2008 Reciprocal interaction with G-actin and tropomyosin is essential for aquaporin-2 trafficking J Cell Biol 182 587 601 18678705 1:CAS:528:DC%2BD1cXpvFKltL4%3D
102. LE O'Brien MMP Zegers KE Mostov 2002 Building epithelial architecture: insights from three-dimensional culture models Nat Rev Mol Cell Biol 3 531 537 12094219 (Pubitemid 34733434)
103. M Papadopoulos A Verkman 2007 Aquaporin-4 and brain edema Pediatr Nephrol 22 778 784 17347837 (Pubitemid 46629610)
104. GM Preston P Agre 1991 Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family Proc Natl Acad Sci U S A 88 11110 11114 1722319 1:CAS:528:DyaK3sXhtF2itrs%3D (Pubitemid 21915989)
105. G Procino C Barbieri G Tamma L De Benedictis JE Pessin M Svelto G Valenti 2008 AQP2 exocytosis in the renal collecting duct-involvement of SNARE isoforms and the regulatory role of Munc18b J Cell Sci 121 2097 2106 18505797 1:CAS:528:DC%2BD1cXovFakt7Y%3D (Pubitemid 352015207)
106. SE Quaggin JA Kreidberg 2008 Development of the renal glomerulus: good neighbors and good fences Development 135 609 620 18184729 1:CAS:528: DC%2BD1cXjsFyhsLw%3D (Pubitemid 351405014)
107. T Rai S Sasaki S Uchida 2006 Polarized trafficking of the aquaporin-3 water channel is mediated by an NH2-terminal sorting signal Am J Physiol Cell Physiol 290 C298 C304 16135541 1:CAS:528:DC%2BD28XhsVSisro%3D
108. R Rao S Patel C Hao J Woodgett R Harris 2010 GSK3{beta} mediates renal response to vasopressin by modulating adenylate cyclase activity J Am Soc Nephrol 21 428 437 20056751 1:CAS:528:DC%2BC3cXjvFClur4%3D
109. JF Roeth JK Sawyer DA Wilner M Peifer 2009 Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm PLoS ONE 4 e7634 19862327
110. MH Roh CJ Liu S Laurinec B Margolis 2002 The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions J Biol Chem 277 27501 27509 12021270 1:CAS:528:DC%2BD38XlvV2hsr8%3D (Pubitemid 34951771)
111. MH Roh O Makarova CJ Liu K Shin S Lee S Laurinec M Goyal R Wiggins B Margolis 2002 The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of crumbs and discs lost J Cell Biol 157 161 172 11927608 1:CAS:528:DC%2BD38Xis1Knsb0%3D (Pubitemid 34847838)
112. S Rohr N Bit-Avragim S Bdelilah-Seyfried 2006 Heart and soul/PRKCi and nagie oko/Mpp 5 regulate myocardial coherence and remodeling during cardiac morphogenesis Development 133 107 115 16319113 1:CAS:528:DC%2BD28XhtFGgur4%3D (Pubitemid 43169325)
113. A Rojek J Praetorius J Frøkiaer S Nielsen RA Fenton 2008 A current view of the mammalian aquaglyceroporins Annu Rev Physiol 70 301 327 17961083 1:CAS:528:DC%2BD1cXkt1eqtrY%3D (Pubitemid 351738182)
114. S Saadoun MC Papadopoulos M Hara-Chikuma AS Verkman 2005 Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption Nature 434 786 792 15815633 1:CAS:528:DC%2BD2MXivFCgurs%3D (Pubitemid 44739524)
115. PJ Savelkoul MF De Y Li EJ Kamsteeg IB Konings SP van der PM Deen 2009 p.R254Q mutation in the aquaporin-2 water channel causing dominant nephrogenic diabetes insipidus is due to a lack of arginine vasopressin-induced phosphorylation Hum Mutat 30 E891 E903 19585583
116. MA Schlüter B Margolis 2009 Apical lumen formation in renal epithelia J Am Soc Nephrol 20 1444 1452 19497970
117. MA Schlüter CS Pfarr J Pieczynski EL Whiteman TW Hurd S Fan CJ Liu B Margolis 2009 Trafficking of crumbs3 during cytokinesis is crucial for lumen formation Mol Biol Cell 20 22 4652 4663 19776356
118. J Schnermann CL Chou T Ma T Traynor MA Knepper AS Verkman 1998 Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice Proc Natl Acad Sci U S A 95 9660 9664 9689137 1:CAS:528:DyaK1cXltlCltrk%3D (Pubitemid 28506288)
119. RW Schrier T Berl RJ Anderson 1979 Osmotic and nonosmotic control of vasopressin release Am J Physiol 236 F321 F332 373467 1:CAS:528: DyaE1MXitVSqtbs%3D
120. K Shin VC Fogg B Margolis 2006 Tight junctions and cell polarity Annu Rev Cell Dev Biol 22 207 235 16771626 1:CAS:528:DC%2BD28Xht1yjs7vK
121. K Shin S Straight B Margolis 2005 PATJ regulates tight junction formation and polarity in mammalian epithelial cells J Cell Biol 168 705 711 15738264 1:CAS:528:DC%2BD2MXitVOmu7c%3D (Pubitemid 40328155)
122. K Shin Q Wang B Margolis 2007 PATJ regulates directional migration of mammalian epithelial cells EMBO Rep 8 158 164 17235357 1:CAS:528: DC%2BD2sXhtFGmtb0%3D (Pubitemid 46420844)
123. JM Shivas HA Morrison D Bilder AR Skop 2010 Polarity and endocytosis: reciprocal regulation Trends Cell Biol 20 445 452 20493706 1:CAS:528: DC%2BC3cXpvVKktLk%3D
124. E Sohara T Rai S Sasaki S Uchida 2006 Physiological roles of AQP7 in the kidney: lessons from AQP7 knockout mice Biochim Biophys Acta BBA Biomembr 1758 1106 1110 1:CAS:528:DC%2BD28Xps1Omsrw%3D (Pubitemid 44373862)
125. SW Straight K Shin VC Fogg S Fan CJ Liu M Roh B Margolis 2004 Loss of PALS1 expression leads to tight junction and polarity defects Mol Biol Cell 15 1981 1990 14718565 1:CAS:528:DC%2BD2cXivFalsbs%3D (Pubitemid 38401844)
126. TX Sun HA Van Y Huang R Bouley M McLaughlin D Brown 2002 Aquaporin-2 localization in clathrin-coated pits: inhibition of endocytosis by dominant-negative dynamin Am J Physiol Ren Physiol 282 F998 F1011 1:CAS:528:DC%2BD38Xks12msr0%3D
127. A Suzuki S Ohno 2006 The PAR-aPKC system: lessons in polarity J Cell Sci 119 979 987 16525119 1:CAS:528:DC%2BD28Xjs1yrsbo%3D
128. Y Tabuse Y Izumi F Piano KJ Kemphues J Miwa S Ohno 1998 Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans Development 125 3607 3614 9716526 1:CAS:528:DyaK1cXmslKmurw%3D (Pubitemid 28469961)
129. Y Tajika T Matsuzaki T Suzuki A Ablimit T Aoki H Hagiwara M Kuwahara S Sasaki K Takata 2005 Differential regulation of AQP2 trafficking in endosomes by microtubules and actin filaments Histochem Cell Biol 124 1 12 16049696 1:CAS:528:DC%2BD2MXpslahu70%3D (Pubitemid 41253158)
130. Y Tajika T Matsuzaki T Suzuki T Aoki H Hagiwara M Kuwahara S Sasaki K Takata 2004 Aquaporin-2 is retrieved to the apical storage compartment via early endosomes and phosphatidylinositol 3-kinase-dependent pathway Endocrinology 145 4375 4383 15155571 1:CAS:528:DC%2BD2cXnt1Citb4%3D (Pubitemid 39120587)
131. K Takata T Matsuzaki Y Tajika 2004 Aquaporins: water channel proteins of the cell membrane Prog Histochem Cytochem 39 1 83 15242101 1:CAS:528: DC%2BD2cXntlyjsrw%3D (Pubitemid 38857834)
132. G Tamma E Klussmann J Oehlke E Krause W Rosenthal M Svelto G Valenti 2005 Actin remodeling requires ERM function to facilitate AQP2 apical targeting J Cell Sci 118 3623 3630 16046477 1:CAS:528:DC%2BD2MXhtVaktrjM (Pubitemid 41309409)
133. Tamma G, Robben JH, Trimpert C, Boone M, Deen PMT (2011) Regulation of AQP2 localization by Ser256 and S261 phosphorylation and ubiquitination. Am J Physiol Cell Physiol (in press)
134. U Tepass 2009 FERM proteins in animal morphogenesis Curr Opin Genet Dev 19 357 367 19596566 1:CAS:528:DC%2BD1MXhtVentLbJ
135. U Tepass E Knust 1993 Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster Dev Biol 159 311 326 8365569 1:CAS:528:DyaK3sXmsVKhsrs%3D (Pubitemid 23287244)
136. G Valenti JS Hugon J Bourguet 1988 To what extent is microtubular network involved in antidiuretic response? Am J Physiol Ren Physiol 255 F1098 F1106 1:CAS:528:DyaL1MXltFGqsA%3D%3D
137. BW van Balkom PJ Savelkoul D Markovich E Hofman S Nielsen SP van der PM Deen 2002 The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel J Biol Chem 277 41473 41479 12194985 (Pubitemid 35257449)
138. AS Verkman 2009 Aquaporins: translating bench research to human disease J Exp Biol 212 1707 1715 19448080 1:CAS:528:DC%2BD1MXptVeis7w%3D
139. JB Wallingford 2010 Planar cell polarity signaling, cilia and polarized ciliary beating Curr Opin Cell Biol 22 597 604 20817501 1:CAS:528: DC%2BC3cXht1Cls7zK
140. Q Wang XW Chen B Margolis 2007 PALS1 regulates E-cadherin trafficking in mammalian epithelial cells Mol Biol Cell 18 874 885 17182851 (Pubitemid 46399493)
141. Q Wang B Margolis 2007 Apical junctional complexes and cell polarity Kidney Int 72 1448 1458 17914350 1:CAS:528:DC%2BD2sXhtlKltLrK (Pubitemid 350197955)
142. X Wei J Malicki 2002 Nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina Nat Genet 31 150 157 11992120 1:CAS:528:DC%2BD38XktVKgsbY%3D
143. OA Weisz E Rodriguez-Boulan 2009 Apical trafficking in epithelial cells: signals, clusters and motors J Cell Sci 122 4253 4266 19923269 1:CAS:528:DC%2BC3cXmtVKltA%3D%3D
144. RB Wellner AT Hoque CM Goldsmith BJ Baum 2000 Evidence that aquaporin-8 is located in the basolateral membrane of rat submandibular gland acinar cells Pflugers Arch 441 49 56 11205061 1:CAS:528:DC%2BD3cXotVeltL8%3D (Pubitemid 32146956)
145. RB Wellner BJ Baum 2001 Polarized sorting of aquaporins 5 and 8 in stable MDCK-II transfectants Biochem Biophys Res Commun 285 1253 1258 11478792 1:CAS:528:DC%2BD3MXlsFChsLc%3D (Pubitemid 32912918)
146. RB Wellner S Hong AP Cotrim WD Swaim BJ Baum 2005 Modifying the NH2 and COOH termini of aquaporin-5: effects on localization in polarized epithelial cells Tissue Eng 11 1449 1458 16259600 1:CAS:528:DC%2BD2MXhtFKlsL7K (Pubitemid 41636431)
147. CD Wells JP Fawcett A Traweger Y Yamanaka M Goudreault K Elder S Kulkarni G Gish C Virag C Lim K Colwill, et al. 2006 A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells Cell 125 535 548 16678097 1:CAS:528:DC%2BD28XkslCjtLc%3D
148. MA Welte 2004 Bidirectional transport along microtubules Curr Biol 14 R525 R537 15242636 1:CAS:528:DC%2BD2cXlsFyrtrs%3D
149. T Yamanaka S Ohno 2008 Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth Front Biosci 13 6693 6707 18508688 1:CAS:528:DC%2BD1cXnsVOitb4%3D
150. M Yasui A Hazama TH Kwon S Nielsen WB Guggino P Agre 1999 Rapid gating and anion permeability of an intracellular aquaporin Nature 402 184 187 10647010 1:CAS:528:DyaK1MXnsVektLg%3D
151. M Yasui TH Kwon MA Knepper S Nielsen P Agre 1999 Aquaporin-6: an intracellular vesicle water channel protein in renal epithelia Proc Natl Acad Sci U S A 96 5808 5813 10318966 1:CAS:528:DyaK1MXjtFCnurc%3D (Pubitemid 29234700)
152. W Zhang E Zitron M Hömme L Kihm C Morath D Scherer S Hegge D Thomas CP Schmitt M Zeier H Katus, et al. 2007 Aquaporin-1 channel function is positively regulated by protein kinase C J Biol Chem 282 20933 20940 17522053 1:CAS:528:DC%2BD2sXns1ygu7g%3D (Pubitemid 47099941)