Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

Gene

Volumn 302, Issue 1-2, 2003, Pages 21-29

  Makarova, Olga ^a   Roh, Michael H ^a   Liu, Chia Jen ^a   Laurinec, Stephanie ^a   Margolis, Ben ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Discs lost; Pals1 associated tight junction; Polarity; Postsynaptic density 95 discs large zona occludens1 domain; Stardust; Tight junction

Indexed keywords

COMPLEMENTARY DNA; LINK PROTEIN; M PROTEIN; MEMBRANE PROTEIN; PROTEIN PALS1; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL POLARITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA; EYE DISEASE; GENE MUTATION; GENE TARGETING; GLYCOSYLATION; HUMAN; HUMAN CELL; LEBER CONGENITAL AMAUROSIS; MAMMAL; MOUSE; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; RAT; RETINITIS PIGMENTOSA; TIGHT JUNCTION;

MAMMALIA;

EID: 0037413672     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378111902010843     Document Type: Article

References (28)

1. Bachmann A., Schneider M., Thellenberg E., Grawe F., Knust E. Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity. Nature. 414:2001;638-643.
2. Bhat M.A., Izaddoost S., Lu Y., Cho K.O., Choi K.W., Bellen H.J. Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. Cell. 96:1999;833-845.
3. Bilder D. PDZ proteins and polarity: functions from the fly. Trends Genet. 17:2001;511-519.
4. den Hollander A.I., Heckenlively J.R., van den Born L.I., de Kok Y.J., van der Velde-Visser S.D., Kellner U., Jurklies B., van Schooneveld M.J., Blankenagel A., Rohrschneider K., Wissinger B., Cruysberg J.R., Deutman A.F., Brunner H.G., Apfelstedt-Sylla E., Hoyng C.B., Cremers F.P. Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene. Am. J. Hum. Genet. 69:2001;198-203.
5. den Hollander A.I., Johnson K., de Kok Y.J., Klebes A., Brunner H.G., Knust E., Cremers F.P. CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila. Hum. Mol. Genet. 10:2001;2767-2773.
6. Doerks T., Bork P., Kamberov E., Makarova O., Muecke S., Margolis B. L27, a novel heterodimerization domain in receptor targeting proteins Lin-2 and Lin-7. Trends Biochem. Sci. 25:2000;317-318.
7. Hong Y., Stronach B., Perrimon N., Jan L.Y., Jan Y.N. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature. 414:2001;634-638.
8. Hoover K.B., Bryant P.J. The genetics of the protein 4.1 family: organizers of the membrane and cytoskeleton. Curr. Opin. Cell Biol. 12:2000;229-234.
9. Hung A.Y., Sheng M. PDZ domains: structural modules for protein complex assembly. J. Biol. Chem. 277:2002;5699-5702.
10. Izaddoost S., Nam S.C., Bhat M.A., Bellen H.J., Choi K.W. Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres. Nature. 416:2002;178-183.
11. Kaech S.M., Whitfield C.W., Kim S.K. The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells. Cell. 94:1998;761-771.
12. Kamberov E., Makarova O., Roh M., Liu A., Karnak D., Straight S., Margolis B. Molecular cloning and characterization of Pals, proteins associated with mLin-7. J. Biol. Chem. 275:2000;11425-11431.
13. Klebes A., Knust E. A conserved motif in Crumbs is required for E-cadherin localization and zonula adherens formation in Drosophila. Curr. Biol. 10:2000;76-85.
14. Krogh A., Larsson B., von Heijne G., Sonnhammer E.L. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305:2001;567-580.
15. Lemmers C., Medina E., Delgrossi M.H., Michel D., Arsanto J.P., Le Bivic A. hINADl/PATJ, a homolog of Discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells. J. Biol. Chem. ? 2002;? in press.
16. Makarova O., Kamberov E., Margolis B. Generation of deletion and point mutations with one primer in a single cloning step. Biotechniques. 29:2000;970-972.
17. Muller H.A., Wieschaus E. Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J. Cell Biol. 134:1996;149-163.
18. Nielsen H., Engelbrecht J., Brunak S., von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1997;1-6.
19. Pellikka M., Tanentzapf G., Pinto M., Smith C., McGlade C.J., Ready D.F., Tepass U. Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis. Nature. 416:2002;143-149.
20. Perego C., Vanoni C., Villa A., Longhi R., Kaech S.M., Frohli E., Hajnal A., Kim S.K., Pietrini G. PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells. EMBO J. 18:1999;2384-2393.
21. Roh M.H., Makarova O., Liu C.J., Shin K., Lee S., Laurinec S., Goyal M., Wiggins R., Margolis B. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. J. Cell Biol. 157:2002;161-172.
22. Stevenson B.R., Keon B.H. The tight junction: morphology to molecules. Annu. Rev. Cell Dev. Biol. 14:1998;89-109.
23. Straight S.W., Karnak D., Borg J.P., Kamberov E., Dare H., Margolis B., Wade J.B. mLin-7 is localized to the basolateral surface of renal epithelia via its NH(2) terminus. Am. J. Physiol. Renal Physiol. 278:2000;F464-F475.
24. Straight S.W., Chen L., Karnak D., Margolis B. Interaction with mLin-7 alters the targeting of endocytosed transmembrane proteins in mammalian epithelial cells. Mol. Biol. Cell. 12:2001;1329-1340.
25. Tepass U. Crumbs, a component of the apical membrane, is required for zonula adherens formation in primary epithelia of Drosophila. Dev. Biol. 177:1996;217-225.
26. Tepass U., Theres C., Knust E. Crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell. 61:1990;787-799.
27. Wodarz A., Hinz U., Engelbert M., Knust E. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell. 82:1995;67-76.
28. Yeaman C., Grindstaff K.K., Nelson W.J. New perspectives on mechanisms involved in generating epithelial cell polarity. Physiol. Rev. 79:1999;73-98.