Missorting of the Aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is due to the loss of E258

Pflugers Archiv European Journal of Physiology

Volumn 455, Issue 6, 2008, Pages 1041-1054

  Kamsteeg, Erik Jan ^a   Savelkoul, Paul J M ^a   Hendriks, Giel ^b   Konings, Irene B M ^a   Nivillac, Nicole M I ^a   Lagendijk, Anne Karine ^a   Van Der Sluijs, Peter ^b   Deen, Peter M T ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

AQP2; Membrane trafficking; Phosphorylation; Ubiquitination; Water channel

Indexed keywords

AQUAPORIN 2; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; KIDNEY CELL; LYSOSOME; MUTATIONAL ANALYSIS; NEPHROGENIC DIABETES INSIPIDUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UBIQUITINATION;

ANIMALS; AQUAPORIN 2; BIOTINYLATION; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CYTOPLASMIC VESICLES; DENSITOMETRY; DIABETES INSIPIDUS, NEPHROGENIC; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; HALF-LIFE; IMMUNOPRECIPITATION; LYSOSOMES; MUTATION; PHOSPHORYLATION; PROTEIN KINASE C; SUBCELLULAR FRACTIONS; TRANSFECTION; UBIQUITINS;

EID: 38649110187     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0364-6     Document Type: Article

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