Peptidomimetic inhibitors of bacterial peptide deformylase

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 13, 2011, Pages 4032-4035

  East, Stephen P ^a,b   Ayscough, Andrew ^a   Toogood Johnson, Ian ^a   Taylor, Steven ^a   Thomas, Wayne ^a  

^a Vernalis PLC   (United Kingdom)

^b EVOTEC UK LTD   (United Kingdom)

Author keywords

Antibacterial; Azapeptide; Metalloprotease; Peptide deformylase; Peptidomimetic

Indexed keywords

PEPTIDE DEFORMYLASE; PEPTIDE DEFORMYLASE INHIBITOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; NONHUMAN; PROTEIN MOTIF; RESPIRATORY TRACT INFECTION; STREPTOCOCCUS PNEUMONIAE;

AMIDOHYDROLASES; AMINES; ANTI-BACTERIAL AGENTS; AZA COMPOUNDS; CYCLIZATION; HAEMOPHILUS INFLUENZAE; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; PEPTIDOMIMETICS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE;

EID: 79958724148     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.132     Document Type: Article

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