Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 12, 2010, Pages 3592-3595

  Shi, Wei ^a   Duan, Yuejiao ^a   Qian, Yu ^a   Li, Ming ^a   Yang, Liping ^a   Hu, Wenhao ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

Antibiotics; Drug resistant bacteria; PDF inhibitor

Indexed keywords

2,5 DIHYDROPYRROLE FORMYL HYDROXYAMINO DERIVATIVE; ANTIINFECTIVE AGENT; CIPROFLOXACIN; LINEZOLID; PENICILLIN G; PEPTIDE DEFORMYLASE INHIBITOR; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN;

AMIDOHYDROLASES; AMINES; ANTI-BACTERIAL AGENTS; DRUG DESIGN; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77954213884     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.123     Document Type: Article

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