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Volumn 7, Issue 3-4, 2010, Pages 89-97

Animal models of pulmonary hypertension: Role in translational research

Author keywords

[No Author keywords available]

Indexed keywords

BAY 63 252; BLEOMYCIN; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); IMATINIB; MONOCROTALINE; PROSTACYCLIN; PROSTACYCLIN DERIVATIVE; RHO KINASE INHIBITOR; RIOCIGUAT; SEMAXANIB; SILDENAFIL; SIMVASTATIN; SORAFENIB; UNCLASSIFIED DRUG;

EID: 79958697718     PISSN: 17406757     EISSN: 17406757     Source Type: Journal    
DOI: 10.1016/j.ddmod.2011.02.002     Document Type: Review
Times cited : (14)

References (49)
  • 1
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; And the Pulmonary Hypertension Association
    • V.V. McLaughlin ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association J. Am. Coll. Cardiol. 53 2009 1573 1619
    • (2009) J. Am. Coll. Cardiol. , vol.53 , pp. 1573-1619
    • McLaughlin, V.V.1
  • 2
    • 74449089564 scopus 로고    scopus 로고
    • Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan
    • S. Schroll Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan Respir. Physiol. Neurobiol. 170 2010 32 36
    • (2010) Respir. Physiol. Neurobiol. , vol.170 , pp. 32-36
    • Schroll, S.1
  • 3
    • 53849089139 scopus 로고    scopus 로고
    • Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
    • R.T. Schermuly Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension Eur. Respir. J. 32 2008 881 891
    • (2008) Eur. Respir. J. , vol.32 , pp. 881-891
    • Schermuly, R.T.1
  • 4
    • 8644256840 scopus 로고    scopus 로고
    • BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
    • H. Beppu BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia Am. J. Physiol. Lung Cell Mol. Physiol. 287 2004 L1241 L1247
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.287
    • Beppu, H.1
  • 5
    • 59849118025 scopus 로고    scopus 로고
    • Interleukin-6 overexpression induces pulmonary hypertension
    • M.K. Steiner Interleukin-6 overexpression induces pulmonary hypertension Circ. Res. 104 2004 236 244 28p
    • (2004) Circ. Res. , vol.104 , pp. 236-244
    • Steiner, M.K.1
  • 7
    • 33745155785 scopus 로고    scopus 로고
    • An Abnormal mitochondrial-hypoxia inducible factor-1α-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: Similarities to human pulmonary arterial hypertension
    • DOI 10.1161/CIRCULATIONAHA.105.609008, PII 0000301720060606000012
    • S. Bonnet An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension Circulation 113 2006 2630 2641 (Pubitemid 43948012)
    • (2006) Circulation , vol.113 , Issue.22 , pp. 2630-2641
    • Bonnet, S.1    Michelakis, E.D.2    Porter, C.J.3    Andrade-Navarro, M.A.4    Thebaud, B.5    Bonnet, S.6    Haromy, A.7    Harry, G.8    Moudgil, R.9    McMurtry, M.S.10    Weir, E.K.11    Archer, S.L.12
  • 10
    • 0034886023 scopus 로고    scopus 로고
    • Chronic intermittent hypercapnic hypoxia increases pulmonary arterial pressure and haematocrit in rats
    • DOI 10.1183/09031936.01.00078801
    • M. McGuire, and A. Bradford Chronic intermittent hypercapnic hypoxia increases pulmonary arterial pressure and haematocrit in rats Eur. Respir. J. 18 2001 279 285 (Pubitemid 32776402)
    • (2001) European Respiratory Journal , vol.18 , Issue.2 , pp. 279-285
    • McGuire, M.1    Bradford, A.2
  • 11
    • 33646378188 scopus 로고    scopus 로고
    • Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig
    • DOI 10.1152/japplphysiol.00274.2005
    • J.L. Wright Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig J. Appl. Physiol. 100 2006 672 678 (Pubitemid 43671624)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.2 , pp. 672-678
    • Wright, J.L.1    Tai, H.2    Churg, A.3
  • 14
    • 0030727379 scopus 로고    scopus 로고
    • Models of persistent pulmonary hypertension of the newborn (PPHN) and the role of cyclic guanosine monophosphate (GMP) in pulmonary vasorelaxation
    • DOI 10.1016/S0146-0005(97)80005-5
    • R. Steinhorn Models of persistent pulmonary hypertension of the newborn (PPHN) and the role of cyclic guanosine monophosphate (GMP) in pulmonary vasorelaxation Semin. Perinatol. 21 1997 393 408 (Pubitemid 27459488)
    • (1997) Seminars in Perinatology , vol.21 , Issue.5 , pp. 393-408
    • Steinhorn, R.H.1    Morin III, F.C.2    Fineman, J.R.3
  • 15
    • 0037531464 scopus 로고    scopus 로고
    • Lung structural remodeling and pulmonary hypertension after myocardial infarction: Complete reversal with irbesartan
    • DOI 10.1016/S0008-6363(03)00290-6
    • J. Jasmin Lung structural remodeling and pulmonary hypertension after myocardial infarction: complete reversal with irbesartan Cardiovasc. Res. 58 2003 621 631 (Pubitemid 36694448)
    • (2003) Cardiovascular Research , vol.58 , Issue.3 , pp. 621-631
    • Jasmin, J.-F.1    Calderone, A.2    Leung, T.-K.3    Villeneuve, L.4    Dupuis, J.5
  • 16
    • 70349768148 scopus 로고    scopus 로고
    • Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques
    • P.B. Sehgal Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques Am. J. Physiol. Lung Cell Mol. Physiol. 297 2009 L729 L737
    • (2009) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.297
    • Sehgal, P.B.1
  • 17
    • 76749098219 scopus 로고    scopus 로고
    • Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis
    • A. Crosby Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis Am. J. Respir. Crit. Care Med. 181 2010 279 288
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , pp. 279-288
    • Crosby, A.1
  • 18
    • 0242578573 scopus 로고    scopus 로고
    • Chemokines accumulate in the lungs of rats with severe pulmonary embolism induced by polystyrene microspheres
    • J. Zagorski Chemokines accumulate in the lungs of rats with severe pulmonary embolism induced by polystyrene microspheres J. Immunol. 171 2003 5529 5536 (Pubitemid 37432843)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 5529-5536
    • Zagorski, J.1    Debelak, J.2    Gellar, M.3    Watts, J.A.4    Kline, J.A.5
  • 19
    • 58849142043 scopus 로고    scopus 로고
    • Regulation of hypoxic pulmonary vasoconstriction: Basic mechanisms
    • N. Sommer Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms Eur. Respir. J. 32 2008 1639 1651
    • (2008) Eur. Respir. J. , vol.32 , pp. 1639-1651
    • Sommer, N.1
  • 20
    • 33751560248 scopus 로고    scopus 로고
    • Hypoxia in lung vascular biology and disease
    • DOI 10.1016/j.cardiores.2006.07.003, PII S0008636306003063
    • N. Weissmann Hypoxia in lung vascular biology and disease Cardiovasc. Res. 71 2006 618 619 (Pubitemid 44848017)
    • (2006) Cardiovascular Research , vol.71 , Issue.4 , pp. 618-619
    • Weissmann, N.1    Grimminger, F.2    Seeger, W.3
  • 23
    • 0037192329 scopus 로고    scopus 로고
    • Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension
    • DOI 10.1161/hc0402.102866
    • S.H. Zaidi Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension Circulation 105 2002 516 521 (Pubitemid 34141711)
    • (2002) Circulation , vol.105 , Issue.4 , pp. 516-521
    • Zaidi, S.H.E.1    You, X.-M.2    Ciura, S.3    Husain, M.4    Rabinovitch, M.5
  • 25
    • 0035018667 scopus 로고    scopus 로고
    • Chronic hypoxia decreases K(V) channel expression and function in pulmonary artery myocytes
    • O. Platoshyn Chronic hypoxia decreases K(V) channel expression and function in pulmonary artery myocytes Am. J. Physiol. Lung Cell Mol. Physiol. 280 2001 L801 L812
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.280
    • Platoshyn, O.1
  • 26
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • K.R. Stenmark Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure Am. J. Physiol. Lung Cell Mol. Physiol. 297 2009 L1013 L1032
    • (2009) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.297
    • Stenmark, K.R.1
  • 27
    • 67651238345 scopus 로고    scopus 로고
    • Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment
    • D.L. Burke Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment Am. J. Physiol. Lung Cell Mol. Physiol. 297 2009 L238 L250
    • (2009) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.297
    • Burke, D.L.1
  • 28
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • DOI 10.1096/fj.00-0343com
    • L. Taraseviciene-Stewart Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension FASEB J. 15 2001 427 438 (Pubitemid 32141434)
    • (2001) FASEB Journal , vol.15 , Issue.2 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6    Voelkel, N.F.7    Tuder, R.M.8
  • 29
    • 84916362625 scopus 로고
    • Pulmonary arteritis produced in rat by feeding Crotalaria spectabilis
    • J.J. Lalich, and L. Merkov Pulmonary arteritis produced in rat by feeding Crotalaria spectabilis Lab Invest. 10 1961 744 750
    • (1961) Lab Invest. , vol.10 , pp. 744-750
    • Lalich, J.J.1    Merkov, L.2
  • 31
    • 0022084743 scopus 로고
    • Alveolar inflammation and arachidonate metabolism in monocrotaline- induced pulmonary hypertension
    • K.R. Stenmark Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension Am. J. Physiol. 248 1985 H859 H866
    • (1985) Am. J. Physiol. , vol.248
    • Stenmark, K.R.1
  • 34
    • 63349108329 scopus 로고    scopus 로고
    • Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury
    • R. Dumitrascu Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury BMC. Pulm. Med. 8 2008 25
    • (2008) BMC. Pulm. Med. , vol.8 , pp. 25
    • Dumitrascu, R.1
  • 35
    • 34250219392 scopus 로고    scopus 로고
    • Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice
    • W. Raoul Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice Respir. Res. 8 2007 8
    • (2007) Respir. Res. , vol.8 , pp. 8
    • Raoul, W.1
  • 38
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • The Primary Pulmonary Hypertension Study Group
    • R.J. Barst A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group N. Engl. J. Med. 334 1996 296 302
    • (1996) N. Engl. J. Med. , vol.334 , pp. 296-302
    • Barst, R.J.1
  • 39
    • 0028300556 scopus 로고
    • BQ123, an ETA-receptor antagonist, attenuates hypoxic pulmonary hypertension in rats
    • S.T. Bonvallet BQ123, an ETA-receptor antagonist, attenuates hypoxic pulmonary hypertension in rats Am. J. Physiol. 266 1994 H1327 H1331
    • (1994) Am. J. Physiol. , vol.266
    • Bonvallet, S.T.1
  • 40
    • 57449103127 scopus 로고    scopus 로고
    • Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
    • X. Jais Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial J. Am. Coll. Cardiol. 52 2008 2127 2134
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 2127-2134
    • Jais, X.1
  • 44
    • 77953273837 scopus 로고    scopus 로고
    • Simvastatin as a treatment for pulmonary hypertension trial
    • M.R. Wilkins Simvastatin as a treatment for pulmonary hypertension trial Am. J. Respir. Crit. Care Med. 181 2010 1106 1113
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , pp. 1106-1113
    • Wilkins, M.R.1
  • 45
    • 77956664858 scopus 로고    scopus 로고
    • Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: A phase II study
    • H.A. Ghofrani Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study Eur. Respir. J. 36 2010 792 799
    • (2010) Eur. Respir. J. , vol.36 , pp. 792-799
    • Ghofrani, H.A.1
  • 46
    • 77956709644 scopus 로고    scopus 로고
    • Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy
    • H.A. Ghofrani Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy Am. J. Respir. Crit. Care Med. 182 2010 1171 1177
    • (2010) Am. J. Respir. Crit. Care Med. , vol.182 , pp. 1171-1177
    • Ghofrani, H.A.1
  • 47
    • 57149145794 scopus 로고    scopus 로고
    • Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling
    • M. Klein Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling Circulation 118 2008 2081 2090
    • (2008) Circulation , vol.118 , pp. 2081-2090
    • Klein, M.1
  • 48
    • 77149179051 scopus 로고    scopus 로고
    • A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension
    • M. Gomberg-Maitland A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension Clin. Pharmacol. Ther. 87 2010 303 310
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 303-310
    • Gomberg-Maitland, M.1
  • 49
    • 77957828780 scopus 로고    scopus 로고
    • Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension
    • B.K. Dahal Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension Eur Respir J. 36 2010 808 818
    • (2010) Eur Respir J. , vol.36 , pp. 808-818
    • Dahal, B.K.1


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