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Volumn 53, Issue 17, 2009, Pages 1573-1619

ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension. A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association Developed in Collaboration With the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association

Author keywords

ACCF AHA Expert Consensus Document; endothelin receptor antagonists; hemodynamics; phosphodiesterase inhibitors; prostacyclin; pulmonary arterial hypertension; pulmonary hypertension

Indexed keywords

AMBRISENTAN; AMLODIPINE; BOSENTAN; DILTIAZEM; ENDOTHELIN RECEPTOR ANTAGONIST; ILOPROST; NIFEDIPINE; PLACEBO; PROSTACYCLIN; SILDENAFIL; SITAXSENTAN; TADALAFIL; UNIPROST; VERAPAMIL; WARFARIN;

EID: 64849109410     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.01.004     Document Type: Review
Times cited : (1427)

References (242)
  • 1
    • 33646269035 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in France: results from a national registry
    • Humbert M., Sitbon O., Chaouat A., et al. Pulmonary arterial hypertension in France: results from a national registry. Am J Respir Crit Care Med 173 (2006) 1023-1030
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 1023-1030
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3
  • 2
    • 37549033243 scopus 로고    scopus 로고
    • A USA-based registry for pulmonary arterial hypertension: 1982-2006
    • Thenappan T., Shah S.J., Rich S., et al. A USA-based registry for pulmonary arterial hypertension: 1982-2006. Eur Respir J 30 (2007) 1103-1110
    • (2007) Eur Respir J , vol.30 , pp. 1103-1110
    • Thenappan, T.1    Shah, S.J.2    Rich, S.3
  • 3
    • 3142692425 scopus 로고    scopus 로고
    • Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • McGoon M., Gutterman D., Steen V., et al. Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 14S-34S
    • (2004) Chest , vol.126
    • McGoon, M.1    Gutterman, D.2    Steen, V.3
  • 4
    • 0022780559 scopus 로고
    • Proceedings of National Heart, Lung, and Blood Institute pediatric cardiology workshop: pulmonary hypertension
    • Friedman W.F. Proceedings of National Heart, Lung, and Blood Institute pediatric cardiology workshop: pulmonary hypertension. Pediatr Res 20 (1986) 811-824
    • (1986) Pediatr Res , vol.20 , pp. 811-824
    • Friedman, W.F.1
  • 5
    • 33750560212 scopus 로고    scopus 로고
    • Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure
    • Voelkel N.F., Quaife R.A., Leinwand L.A., et al. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation 114 (2006) 1883-1891
    • (2006) Circulation , vol.114 , pp. 1883-1891
    • Voelkel, N.F.1    Quaife, R.A.2    Leinwand, L.A.3
  • 6
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S., Kaufmann E., and Levy P.S. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327 (1992) 76-81
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 7
    • 20544448927 scopus 로고    scopus 로고
    • Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
    • Sitbon O., Humbert M., Jais X., et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111 (2005) 3105-3111
    • (2005) Circulation , vol.111 , pp. 3105-3111
    • Sitbon, O.1    Humbert, M.2    Jais, X.3
  • 8
    • 0034727717 scopus 로고    scopus 로고
    • Primary pulmonary hypertension: a vascular biology and translational research "Work in progress"
    • Archer S., and Rich S. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation 102 (2000) 2781-2791
    • (2000) Circulation , vol.102 , pp. 2781-2791
    • Archer, S.1    Rich, S.2
  • 9
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Farber H.W., and Loscalzo J. Pulmonary arterial hypertension. N Engl J Med 351 (2004) 1655-1665
    • (2004) N Engl J Med , vol.351 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 10
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension. A national prospective study
    • Rich S., Dantzker D.R., Ayres S.M., et al. Primary pulmonary hypertension. A national prospective study. Ann Intern Med 107 (1987) 216-223
    • (1987) Ann Intern Med , vol.107 , pp. 216-223
    • Rich, S.1    Dantzker, D.R.2    Ayres, S.M.3
  • 11
    • 0033838125 scopus 로고    scopus 로고
    • Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
    • Deng Z., Morse J.H., Slager S.L., et al. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet 67 (2000) 737-744
    • (2000) Am J Hum Genet , vol.67 , pp. 737-744
    • Deng, Z.1    Morse, J.H.2    Slager, S.L.3
  • 12
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium
    • Lane K.B., Machado R.D., Pauciulo M.W., et al. Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium. Nat Genet 26 (2000) 81-84
    • (2000) Nat Genet , vol.26 , pp. 81-84
    • Lane, K.B.1    Machado, R.D.2    Pauciulo, M.W.3
  • 13
    • 0035797556 scopus 로고    scopus 로고
    • Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia
    • Trembath R.C., Thomson J.R., Machado R.D., et al. Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia. N Engl J Med 345 (2001) 325-334
    • (2001) N Engl J Med , vol.345 , pp. 325-334
    • Trembath, R.C.1    Thomson, J.R.2    Machado, R.D.3
  • 14
    • 33744970745 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
    • Guignabert C., Izikki M., Tu L.I., et al. Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res 98 (2006) 1323-1330
    • (2006) Circ Res , vol.98 , pp. 1323-1330
    • Guignabert, C.1    Izikki, M.2    Tu, L.I.3
  • 15
    • 2342486700 scopus 로고    scopus 로고
    • Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle
    • West J., Fagan K., Steudel W., et al. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res 94 (2004) 1109-1114
    • (2004) Circ Res , vol.94 , pp. 1109-1114
    • West, J.1    Fagan, K.2    Steudel, W.3
  • 16
    • 0029033224 scopus 로고
    • Increased plasma serotonin in primary pulmonary hypertension
    • Herve P., Launay J.M., Scrobohaci M.L., et al. Increased plasma serotonin in primary pulmonary hypertension. Am J Med 99 (1995) 249-254
    • (1995) Am J Med , vol.99 , pp. 249-254
    • Herve, P.1    Launay, J.M.2    Scrobohaci, M.L.3
  • 17
    • 0026628265 scopus 로고
    • An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
    • Christman B.W., McPherson C.D., Newman J.H., et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med 327 (1992) 70-75
    • (1992) N Engl J Med , vol.327 , pp. 70-75
    • Christman, B.W.1    McPherson, C.D.2    Newman, J.H.3
  • 18
    • 0027324745 scopus 로고
    • Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
    • Giaid A., Yanagisawa M., Langleben D., et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 328 (1993) 1732-1739
    • (1993) N Engl J Med , vol.328 , pp. 1732-1739
    • Giaid, A.1    Yanagisawa, M.2    Langleben, D.3
  • 19
    • 0026034713 scopus 로고
    • Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?
    • Stewart D.J., Levy R.D., Cernacek P., et al. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?. Ann Intern Med 114 (1991) 464-469
    • (1991) Ann Intern Med , vol.114 , pp. 464-469
    • Stewart, D.J.1    Levy, R.D.2    Cernacek, P.3
  • 20
    • 0033032949 scopus 로고    scopus 로고
    • Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
    • Tuder R.M., Cool C.D., Geraci M.W., et al. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am J Respir Crit Care Med 159 (1999) 1925-1932
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1925-1932
    • Tuder, R.M.1    Cool, C.D.2    Geraci, M.W.3
  • 21
    • 0035171979 scopus 로고    scopus 로고
    • Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension
    • Rubens C., Ewert R., Halank M., et al. Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest 120 (2001) 1562-1569
    • (2001) Chest , vol.120 , pp. 1562-1569
    • Rubens, C.1    Ewert, R.2    Halank, M.3
  • 22
    • 0030955626 scopus 로고    scopus 로고
    • Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene
    • Steudel W., Ichinose F., Huang P.L., et al. Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ Res 81 (1997) 34-41
    • (1997) Circ Res , vol.81 , pp. 34-41
    • Steudel, W.1    Ichinose, F.2    Huang, P.L.3
  • 23
    • 0034776773 scopus 로고    scopus 로고
    • Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
    • Eddahibi S., Humbert M., Fadel E., et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J Clin Invest 108 (2001) 1141-1150
    • (2001) J Clin Invest , vol.108 , pp. 1141-1150
    • Eddahibi, S.1    Humbert, M.2    Fadel, E.3
  • 24
    • 0041326610 scopus 로고    scopus 로고
    • Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension
    • Marcos E., Adnot S., Pham M.H., et al. Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension. Am J Respir Crit Care Med 168 (2003) 487-493
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 487-493
    • Marcos, E.1    Adnot, S.2    Pham, M.H.3
  • 25
    • 0038369941 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension
    • Petkov V., Mosgoeller W., Ziesche R., et al. Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension. J Clin Invest 111 (2003) 1339-1346
    • (2003) J Clin Invest , vol.111 , pp. 1339-1346
    • Petkov, V.1    Mosgoeller, W.2    Ziesche, R.3
  • 26
    • 18744413239 scopus 로고    scopus 로고
    • Pathobiology of pulmonary arterial hypertension
    • Eddahibi S., Morrell N., d'Ortho M.P., et al. Pathobiology of pulmonary arterial hypertension. Eur Respir J 20 (2002) 1559-1572
    • (2002) Eur Respir J , vol.20 , pp. 1559-1572
    • Eddahibi, S.1    Morrell, N.2    d'Ortho, M.P.3
  • 27
    • 33745155785 scopus 로고    scopus 로고
    • An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension
    • Bonnet S., Michelakis E.D., Porter C.J., et al. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation 113 (2006) 2630-2641
    • (2006) Circulation , vol.113 , pp. 2630-2641
    • Bonnet, S.1    Michelakis, E.D.2    Porter, C.J.3
  • 28
    • 0032492407 scopus 로고    scopus 로고
    • Attenuated K+ channel gene transcription in primary pulmonary hypertension
    • Yuan X.J., Wang J., Juhaszova M., et al. Attenuated K+ channel gene transcription in primary pulmonary hypertension. Lancet 351 (1998) 726-727
    • (1998) Lancet , vol.351 , pp. 726-727
    • Yuan, X.J.1    Wang, J.2    Juhaszova, M.3
  • 29
    • 34547456414 scopus 로고    scopus 로고
    • The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
    • Bonnet S., Rochefort G., Sutendra G., et al. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A 104 (2007) 11418-11423
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11418-11423
    • Bonnet, S.1    Rochefort, G.2    Sutendra, G.3
  • 30
    • 2942541475 scopus 로고    scopus 로고
    • Cellular and molecular pathobiology of pulmonary arterial hypertension
    • Humbert M., Morrell N.W., Archer S.L., et al. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol 43 (2004) 13S-24S
    • (2004) J Am Coll Cardiol , vol.43
    • Humbert, M.1    Morrell, N.W.2    Archer, S.L.3
  • 31
    • 0033989282 scopus 로고    scopus 로고
    • Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease
    • Cowan K.N., Jones P.L., and Rabinovitch M. Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease. J Clin Invest 105 (2000) 21-34
    • (2000) J Clin Invest , vol.105 , pp. 21-34
    • Cowan, K.N.1    Jones, P.L.2    Rabinovitch, M.3
  • 32
    • 13444279874 scopus 로고    scopus 로고
    • Pathogenesis of pulmonary arterial hypertension: the need for multiple hits
    • Yuan J.X., and Rubin L.J. Pathogenesis of pulmonary arterial hypertension: the need for multiple hits. Circulation 111 (2005) 534-538
    • (2005) Circulation , vol.111 , pp. 534-538
    • Yuan, J.X.1    Rubin, L.J.2
  • 33
    • 2942522878 scopus 로고    scopus 로고
    • Clinical classification of pulmonary hypertension
    • Simonneau G., Galie N., Rubin L., et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 43 Suppl 1 (2004) S5-S12
    • (2004) J Am Coll Cardiol , vol.43 , Issue.SUPPL. 1
    • Simonneau, G.1    Galie, N.2    Rubin, L.3
  • 34
    • 1142303693 scopus 로고    scopus 로고
    • Unexplained severe pulmonary hypertension in the elderly: report on 14 patients
    • Yigla M., Kramer M.R., Bendayan D., et al. Unexplained severe pulmonary hypertension in the elderly: report on 14 patients. Isr Med Assoc J 6 (2004) 78-81
    • (2004) Isr Med Assoc J , vol.6 , pp. 78-81
    • Yigla, M.1    Kramer, M.R.2    Bendayan, D.3
  • 35
    • 16444370817 scopus 로고    scopus 로고
    • Gross BMPR2 gene rearrangements constitute a new cause for primary pulmonary hypertension
    • Cogan J.D., Vnencak-Jones C.L., Phillips III J.A., et al. Gross BMPR2 gene rearrangements constitute a new cause for primary pulmonary hypertension. Genet Med 7 (2005) 169-174
    • (2005) Genet Med , vol.7 , pp. 169-174
    • Cogan, J.D.1    Vnencak-Jones, C.L.2    Phillips III, J.A.3
  • 36
    • 0035163071 scopus 로고    scopus 로고
    • BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
    • Machado R.D., Pauciulo M.W., Thomson J.R., et al. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet 68 (2001) 92-102
    • (2001) Am J Hum Genet , vol.68 , pp. 92-102
    • Machado, R.D.1    Pauciulo, M.W.2    Thomson, J.R.3
  • 37
    • 0033623296 scopus 로고    scopus 로고
    • Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family
    • Thomson J.R., Machado R.D., Pauciulo M.W., et al. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. J Med Genet 37 (2000) 741-745
    • (2000) J Med Genet , vol.37 , pp. 741-745
    • Thomson, J.R.1    Machado, R.D.2    Pauciulo, M.W.3
  • 38
    • 0035989333 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension and type-I glycogen-storage disease: the serotonin hypothesis
    • Humbert M., Labrune P., Sitbon O., et al. Pulmonary arterial hypertension and type-I glycogen-storage disease: the serotonin hypothesis. Eur Respir J 20 (2002) 59-65
    • (2002) Eur Respir J , vol.20 , pp. 59-65
    • Humbert, M.1    Labrune, P.2    Sitbon, O.3
  • 39
    • 24644475032 scopus 로고    scopus 로고
    • Low frequency of BMPR2 mutations in a German cohort of patients with sporadic idiopathic pulmonary arterial hypertension
    • Koehler R., Grunig E., Pauciulo M.W., et al. Low frequency of BMPR2 mutations in a German cohort of patients with sporadic idiopathic pulmonary arterial hypertension. J Med Genet 41 (2004) e127
    • (2004) J Med Genet , vol.41
    • Koehler, R.1    Grunig, E.2    Pauciulo, M.W.3
  • 40
    • 0029086553 scopus 로고
    • Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension
    • Loyd J.E., Butler M.G., Foroud T.M., et al. Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension. Am J Respir Crit Care Med 152 (1995) 93-97
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 93-97
    • Loyd, J.E.1    Butler, M.G.2    Foroud, T.M.3
  • 41
    • 44949197649 scopus 로고    scopus 로고
    • Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation
    • Sztrymf B., Coulet F., Girerd B., et al. Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation. Am J Respir Crit Care Med 177 (2008) 1377-1383
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1377-1383
    • Sztrymf, B.1    Coulet, F.2    Girerd, B.3
  • 42
    • 29144536869 scopus 로고    scopus 로고
    • Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study
    • Hachulla E., Gressin V., Guillevin L., et al. Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study. Arthritis Rheum 52 (2005) 3792-3800
    • (2005) Arthritis Rheum , vol.52 , pp. 3792-3800
    • Hachulla, E.1    Gressin, V.2    Guillevin, L.3
  • 43
    • 0142187600 scopus 로고    scopus 로고
    • Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach
    • Mukerjee D., St George D., Coleiro B., et al. Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach. Ann Rheum Dis 62 (2003) 1088-1093
    • (2003) Ann Rheum Dis , vol.62 , pp. 1088-1093
    • Mukerjee, D.1    St George, D.2    Coleiro, B.3
  • 44
    • 15444354123 scopus 로고    scopus 로고
    • HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study
    • Opravil M., Pechere M., Speich R., et al. HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study. Am J Respir Crit Care Med 155 (1997) 990-995
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 990-995
    • Opravil, M.1    Pechere, M.2    Speich, R.3
  • 45
    • 37849026480 scopus 로고    scopus 로고
    • Prevalence of HIV-related pulmonary arterial hypertension in the current antiretroviral therapy era
    • Sitbon O., Lascoux-Combe C., Delfraissy J.F., et al. Prevalence of HIV-related pulmonary arterial hypertension in the current antiretroviral therapy era. Am J Respir Crit Care Med 177 (2008) 108-113
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 108-113
    • Sitbon, O.1    Lascoux-Combe, C.2    Delfraissy, J.F.3
  • 46
    • 0026042115 scopus 로고
    • Primary pulmonary hypertension in HIV infection
    • Speich R., Jenni R., Opravil M., et al. Primary pulmonary hypertension in HIV infection. Chest 100 (1991) 1268-1271
    • (1991) Chest , vol.100 , pp. 1268-1271
    • Speich, R.1    Jenni, R.2    Opravil, M.3
  • 47
    • 0033789708 scopus 로고    scopus 로고
    • HIV-Related pulmonary hypertension: analytic review of 131 cases
    • Mehta N.J., Khan I.A., Mehta R.N., et al. HIV-Related pulmonary hypertension: analytic review of 131 cases. Chest 118 (2000) 1133-1141
    • (2000) Chest , vol.118 , pp. 1133-1141
    • Mehta, N.J.1    Khan, I.A.2    Mehta, R.N.3
  • 48
    • 0020640953 scopus 로고
    • Primary pulmonary hypertension and cirrhosis: are they related?
    • McDonnell P.J., Toye P.A., and Hutchins G.M. Primary pulmonary hypertension and cirrhosis: are they related?. Am Rev Respir Dis 127 (1983) 437-441
    • (1983) Am Rev Respir Dis , vol.127 , pp. 437-441
    • McDonnell, P.J.1    Toye, P.A.2    Hutchins, G.M.3
  • 49
    • 0030317077 scopus 로고    scopus 로고
    • Frequency and clinical implications of increased pulmonary artery pressures in liver transplant patients
    • Castro M., Krowka M.J., Schroeder D.R., et al. Frequency and clinical implications of increased pulmonary artery pressures in liver transplant patients. Mayo Clin Proc 71 (1996) 543-551
    • (1996) Mayo Clin Proc , vol.71 , pp. 543-551
    • Castro, M.1    Krowka, M.J.2    Schroeder, D.R.3
  • 50
    • 0021986849 scopus 로고
    • Aminorex and pulmonary hypertension. A review
    • Gurtner H.P. Aminorex and pulmonary hypertension. A review. Cor Vasa 27 (1985) 160-171
    • (1985) Cor Vasa , vol.27 , pp. 160-171
    • Gurtner, H.P.1
  • 51
    • 9444287592 scopus 로고    scopus 로고
    • Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group
    • Abenhaim L., Moride Y., Brenot F., et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group. N Engl J Med 335 (1996) 609-616
    • (1996) N Engl J Med , vol.335 , pp. 609-616
    • Abenhaim, L.1    Moride, Y.2    Brenot, F.3
  • 52
    • 0026041618 scopus 로고
    • Clinical and pathologic manifestations of pulmonary vascular disease in the toxic oil syndrome
    • Gomez-Sanchez M.A., Saenz de la Calzada C., Gomez-Pajuelo C., et al. Clinical and pathologic manifestations of pulmonary vascular disease in the toxic oil syndrome. J Am Coll Cardiol 18 (1991) 1539-1545
    • (1991) J Am Coll Cardiol , vol.18 , pp. 1539-1545
    • Gomez-Sanchez, M.A.1    Saenz de la Calzada, C.2    Gomez-Pajuelo, C.3
  • 53
    • 0026701953 scopus 로고
    • Eosinophilia-myalgia syndrome: the aftermath
    • Sack K.E., and Criswell L.A. Eosinophilia-myalgia syndrome: the aftermath. South Med J 85 (1992) 878-882
    • (1992) South Med J , vol.85 , pp. 878-882
    • Sack, K.E.1    Criswell, L.A.2
  • 54
    • 0028840945 scopus 로고
    • Stimulant-induced pulmonary toxicity
    • Albertson T.E., Walby W.F., and Derlet R.W. Stimulant-induced pulmonary toxicity. Chest 108 (1995) 1140-1149
    • (1995) Chest , vol.108 , pp. 1140-1149
    • Albertson, T.E.1    Walby, W.F.2    Derlet, R.W.3
  • 55
    • 33845942152 scopus 로고    scopus 로고
    • Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?
    • Chin K.M., Channick R.N., and Rubin L.J. Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?. Chest 130 (2006) 1657-1663
    • (2006) Chest , vol.130 , pp. 1657-1663
    • Chin, K.M.1    Channick, R.N.2    Rubin, L.J.3
  • 56
    • 0037441758 scopus 로고    scopus 로고
    • Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival
    • Castro O., Hoque M., and Brown B.D. Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival. Blood 101 (2003) 1257-1261
    • (2003) Blood , vol.101 , pp. 1257-1261
    • Castro, O.1    Hoque, M.2    Brown, B.D.3
  • 57
    • 10744233940 scopus 로고    scopus 로고
    • Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
    • Gladwin M.T., Sachdev V., Jison M.L., et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 350 (2004) 886-895
    • (2004) N Engl J Med , vol.350 , pp. 886-895
    • Gladwin, M.T.1    Sachdev, V.2    Jison, M.L.3
  • 58
    • 34250160518 scopus 로고    scopus 로고
    • Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension
    • Anthi A., Machado R.F., Jison M.L., et al. Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension. Am J Respir Crit Care Med 175 (2007) 1272-1279
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 1272-1279
    • Anthi, A.1    Machado, R.F.2    Jison, M.L.3
  • 59
    • 0035722775 scopus 로고    scopus 로고
    • Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease
    • Klings E.S., and Farber H.W. Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease. Respir Res 2 (2001) 280-285
    • (2001) Respir Res , vol.2 , pp. 280-285
    • Klings, E.S.1    Farber, H.W.2
  • 60
    • 0032189829 scopus 로고    scopus 로고
    • Increased levels of endothelin-1 in plasma of sickle cell anemia patients
    • Rybicki A.C., and Benjamin L.J. Increased levels of endothelin-1 in plasma of sickle cell anemia patients. Blood 92 (1998) 2594-2596
    • (1998) Blood , vol.92 , pp. 2594-2596
    • Rybicki, A.C.1    Benjamin, L.J.2
  • 61
    • 0035383809 scopus 로고    scopus 로고
    • Cardiac involvement in thalassemia intermedia: a multicenter study
    • Aessopos A., Farmakis D., Karagiorga M., et al. Cardiac involvement in thalassemia intermedia: a multicenter study. Blood 97 (2001) 3411-3416
    • (2001) Blood , vol.97 , pp. 3411-3416
    • Aessopos, A.1    Farmakis, D.2    Karagiorga, M.3
  • 62
    • 0031974567 scopus 로고    scopus 로고
    • Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: a case report and review of the literature
    • Hayag-Barin J.E., Smith R.E., and Tucker Jr. F.C. Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: a case report and review of the literature. Am J Hematol 57 (1998) 82-84
    • (1998) Am J Hematol , vol.57 , pp. 82-84
    • Hayag-Barin, J.E.1    Smith, R.E.2    Tucker Jr., F.C.3
  • 63
    • 1542504799 scopus 로고    scopus 로고
    • Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia
    • Abdalla S.A., Gallione C.J., Barst R.J., et al. Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia. Eur Respir J 23 (2004) 373-377
    • (2004) Eur Respir J , vol.23 , pp. 373-377
    • Abdalla, S.A.1    Gallione, C.J.2    Barst, R.J.3
  • 64
    • 0034832857 scopus 로고    scopus 로고
    • Unexplained pulmonary hypertension in chronic myeloproliferative disorders
    • Dingli D., Utz J.P., Krowka M.J., et al. Unexplained pulmonary hypertension in chronic myeloproliferative disorders. Chest 120 (2001) 801-808
    • (2001) Chest , vol.120 , pp. 801-808
    • Dingli, D.1    Utz, J.P.2    Krowka, M.J.3
  • 65
    • 0036433370 scopus 로고    scopus 로고
    • High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension
    • Chu J.W., Kao P.N., Faul J.L., et al. High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension. Chest 122 (2002) 1668-1673
    • (2002) Chest , vol.122 , pp. 1668-1673
    • Chu, J.W.1    Kao, P.N.2    Faul, J.L.3
  • 66
    • 28244467415 scopus 로고    scopus 로고
    • Pulmonary hypertension after splenectomy: a consequence of loss of the splenic filter or is there something more?
    • Peacock A.J. Pulmonary hypertension after splenectomy: a consequence of loss of the splenic filter or is there something more?. Thorax 60 (2005) 983-984
    • (2005) Thorax , vol.60 , pp. 983-984
    • Peacock, A.J.1
  • 67
    • 2942574709 scopus 로고    scopus 로고
    • Pathologic assessment of vasculopathies in pulmonary hypertension
    • Pietra G.G., Capron F., Stewart S., et al. Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol 43 (2004) 25S-32S
    • (2004) J Am Coll Cardiol , vol.43
    • Pietra, G.G.1    Capron, F.2    Stewart, S.3
  • 68
    • 0034538351 scopus 로고    scopus 로고
    • Pulmonary veno-occlusive disease: a case series and new observations
    • Holcomb Jr. B.W., Loyd J.E., Ely E.W., et al. Pulmonary veno-occlusive disease: a case series and new observations. Chest 118 (2000) 1671-1679
    • (2000) Chest , vol.118 , pp. 1671-1679
    • Holcomb Jr., B.W.1    Loyd, J.E.2    Ely, E.W.3
  • 69
    • 0036385781 scopus 로고    scopus 로고
    • Effects of continuous IV prostacyclin in a patient with pulmonary veno-occlusive disease
    • Okumura H., Nagaya N., Kyotani S., et al. Effects of continuous IV prostacyclin in a patient with pulmonary veno-occlusive disease. Chest 122 (2002) 1096-1098
    • (2002) Chest , vol.122 , pp. 1096-1098
    • Okumura, H.1    Nagaya, N.2    Kyotani, S.3
  • 70
    • 3142777629 scopus 로고    scopus 로고
    • Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • McLaughlin V.V., Presberg K.W., Doyle R.L., et al. Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 78S-92S
    • (2004) Chest , vol.126
    • McLaughlin, V.V.1    Presberg, K.W.2    Doyle, R.L.3
  • 71
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo G.E., Barst R.J., Ayres S.M., et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 115 (1991) 343-349
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 72
    • 0022600374 scopus 로고
    • Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis
    • Stupi A.M., Steen V.D., Owens G.R., et al. Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis. Arthritis Rheum 29 (1986) 515-524
    • (1986) Arthritis Rheum , vol.29 , pp. 515-524
    • Stupi, A.M.1    Steen, V.D.2    Owens, G.R.3
  • 73
    • 0037441640 scopus 로고    scopus 로고
    • Outcome in 91 consecutive patients with pulmonary arterial hypertension receiving epoprostenol
    • Kuhn K.P., Byrne D.W., Arbogast P.G., et al. Outcome in 91 consecutive patients with pulmonary arterial hypertension receiving epoprostenol. Am J Respir Crit Care Med 167 (2003) 580-586
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 580-586
    • Kuhn, K.P.1    Byrne, D.W.2    Arbogast, P.G.3
  • 74
    • 33745637694 scopus 로고    scopus 로고
    • Systemic sclerosis associated pulmonary hypertension: improved survival in the current era
    • Williams M.H., Das C., Handler C.E., et al. Systemic sclerosis associated pulmonary hypertension: improved survival in the current era. Heart 92 (2006) 926-932
    • (2006) Heart , vol.92 , pp. 926-932
    • Williams, M.H.1    Das, C.2    Handler, C.E.3
  • 75
    • 0028298825 scopus 로고
    • Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension
    • Petitpretz P., Brenot F., Azarian R., et al. Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension. Circulation 89 (1994) 2722-2727
    • (1994) Circulation , vol.89 , pp. 2722-2727
    • Petitpretz, P.1    Brenot, F.2    Azarian, R.3
  • 76
    • 0030041787 scopus 로고    scopus 로고
    • Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome
    • Hopkins W.E., Ochoa L.L., Richardson G.W., et al. Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome. J Heart Lung Transplant 15 (1996) 100-105
    • (1996) J Heart Lung Transplant , vol.15 , pp. 100-105
    • Hopkins, W.E.1    Ochoa, L.L.2    Richardson, G.W.3
  • 77
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group
    • Barst R.J., Rubin L.J., Long W.A., et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 334 (1996) 296-302
    • (1996) N Engl J Med , vol.334 , pp. 296-302
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 78
    • 0037126044 scopus 로고    scopus 로고
    • Survival in primary pulmonary hypertension: the impact of epoprostenol therapy
    • McLaughlin V.V., Shillington A., and Rich S. Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation 106 (2002) 1477-1482
    • (2002) Circulation , vol.106 , pp. 1477-1482
    • McLaughlin, V.V.1    Shillington, A.2    Rich, S.3
  • 79
    • 0037151645 scopus 로고    scopus 로고
    • Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival
    • Sitbon O., Humbert M., Nunes H., et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol 40 (2002) 780-788
    • (2002) J Am Coll Cardiol , vol.40 , pp. 780-788
    • Sitbon, O.1    Humbert, M.2    Nunes, H.3
  • 80
    • 0033551155 scopus 로고    scopus 로고
    • Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects
    • Rosenzweig E.B., Kerstein D., and Barst R.J. Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects. Circulation 99 (1999) 1858-1865
    • (1999) Circulation , vol.99 , pp. 1858-1865
    • Rosenzweig, E.B.1    Kerstein, D.2    Barst, R.J.3
  • 81
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
    • Badesch D.B., Tapson V.F., McGoon M.D., et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 132 (2000) 425-434
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 82
    • 33845360014 scopus 로고    scopus 로고
    • Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil
    • Barst R.J., Galie N., Naeije R., et al. Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil. Eur Respir J 28 (2006) 1195-1203
    • (2006) Eur Respir J , vol.28 , pp. 1195-1203
    • Barst, R.J.1    Galie, N.2    Naeije, R.3
  • 83
    • 13844280943 scopus 로고    scopus 로고
    • Survival with first-line bosentan in patients with primary pulmonary hypertension
    • McLaughlin V.V., Sitbon O., Badesch D.B., et al. Survival with first-line bosentan in patients with primary pulmonary hypertension. Eur Respir J 25 (2005) 244-249
    • (2005) Eur Respir J , vol.25 , pp. 244-249
    • McLaughlin, V.V.1    Sitbon, O.2    Badesch, D.B.3
  • 84
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S., Kaufmann E., and Levy P.S. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327 (1992) 76-81
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 85
    • 20544448927 scopus 로고    scopus 로고
    • Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
    • Sitbon O., Humbert M., Jais X., et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111 (2005) 3105-3111
    • (2005) Circulation , vol.111 , pp. 3105-3111
    • Sitbon, O.1    Humbert, M.2    Jais, X.3
  • 86
    • 0030813510 scopus 로고    scopus 로고
    • The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension
    • Frank H., Mlczoch J., Huber K., et al. The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension. Chest 112 (1997) 714-721
    • (1997) Chest , vol.112 , pp. 714-721
    • Frank, H.1    Mlczoch, J.2    Huber, K.3
  • 87
    • 0034107636 scopus 로고    scopus 로고
    • Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing
    • Miyamoto S., Nagaya N., Satoh T., et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. Am J Respir Crit Care Med 161 (2000) 487-492
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 487-492
    • Miyamoto, S.1    Nagaya, N.2    Satoh, T.3
  • 88
    • 0037118681 scopus 로고    scopus 로고
    • Assessment of survival in patients with primary pulmonary hypertension: importance of cardiopulmonary exercise testing
    • Wensel R., Opitz C.F., Anker S.D., et al. Assessment of survival in patients with primary pulmonary hypertension: importance of cardiopulmonary exercise testing. Circulation 106 (2002) 319-324
    • (2002) Circulation , vol.106 , pp. 319-324
    • Wensel, R.1    Opitz, C.F.2    Anker, S.D.3
  • 89
    • 34347245928 scopus 로고    scopus 로고
    • Creation of a model comparing 6-minute walk test to metabolic equivalent in evaluating treatment effects in pulmonary arterial hypertension
    • Gomberg-Maitland M., Huo D., Benza R.L., et al. Creation of a model comparing 6-minute walk test to metabolic equivalent in evaluating treatment effects in pulmonary arterial hypertension. J Heart Lung Transplant 26 (2007) 732-738
    • (2007) J Heart Lung Transplant , vol.26 , pp. 732-738
    • Gomberg-Maitland, M.1    Huo, D.2    Benza, R.L.3
  • 90
    • 0028218793 scopus 로고
    • Survival in primary pulmonary hypertension. Validation of a prognostic equation
    • Sandoval J., Bauerle O., Palomar A., et al. Survival in primary pulmonary hypertension. Validation of a prognostic equation. Circulation 89 (1994) 1733-1744
    • (1994) Circulation , vol.89 , pp. 1733-1744
    • Sandoval, J.1    Bauerle, O.2    Palomar, A.3
  • 91
    • 0024359577 scopus 로고
    • Two-dimensional and Doppler-echocardiographic and cardiac catheterization correlates of survival in primary pulmonary hypertension
    • Eysmann S.B., Palevsky H.I., Reichek N., et al. Two-dimensional and Doppler-echocardiographic and cardiac catheterization correlates of survival in primary pulmonary hypertension. Circulation 80 (1989) 353-360
    • (1989) Circulation , vol.80 , pp. 353-360
    • Eysmann, S.B.1    Palevsky, H.I.2    Reichek, N.3
  • 92
    • 0030281648 scopus 로고    scopus 로고
    • Doppler echocardiographic index for assessment of global right ventricular function
    • Tei C., Dujardin K.S., Hodge D.O., et al. Doppler echocardiographic index for assessment of global right ventricular function. J Am Soc Echocardiogr 9 (1996) 838-847
    • (1996) J Am Soc Echocardiogr , vol.9 , pp. 838-847
    • Tei, C.1    Dujardin, K.S.2    Hodge, D.O.3
  • 93
    • 0032076759 scopus 로고    scopus 로고
    • Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension
    • Yeo T.C., Dujardin K.S., Tei C., et al. Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension. Am J Cardiol 81 (1998) 1157-1161
    • (1998) Am J Cardiol , vol.81 , pp. 1157-1161
    • Yeo, T.C.1    Dujardin, K.S.2    Tei, C.3
  • 94
    • 34548303769 scopus 로고    scopus 로고
    • Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension
    • van Wolferen S.A., Marcus J.T., Boonstra A., et al. Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension. Eur Heart J 28 (2007) 1250-1257
    • (2007) Eur Heart J , vol.28 , pp. 1250-1257
    • van Wolferen, S.A.1    Marcus, J.T.2    Boonstra, A.3
  • 95
    • 37549020328 scopus 로고    scopus 로고
    • Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension
    • Gan C.T., Lankhaar J.W., Westerhof N., et al. Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension. Chest 132 (2007) 1906-1912
    • (2007) Chest , vol.132 , pp. 1906-1912
    • Gan, C.T.1    Lankhaar, J.W.2    Westerhof, N.3
  • 96
    • 33646476400 scopus 로고    scopus 로고
    • Serum N-terminal brain natriuretic peptide as a prognostic parameter in patients with pulmonary hypertension
    • Fijalkowska A., Kurzyna M., Torbicki A., et al. Serum N-terminal brain natriuretic peptide as a prognostic parameter in patients with pulmonary hypertension. Chest 129 (2006) 1313-1321
    • (2006) Chest , vol.129 , pp. 1313-1321
    • Fijalkowska, A.1    Kurzyna, M.2    Torbicki, A.3
  • 97
    • 0034702908 scopus 로고    scopus 로고
    • Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension
    • Nagaya N., Nishikimi T., Uematsu M., et al. Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension. Circulation 102 (2000) 865-870
    • (2000) Circulation , vol.102 , pp. 865-870
    • Nagaya, N.1    Nishikimi, T.2    Uematsu, M.3
  • 98
    • 0032814812 scopus 로고    scopus 로고
    • Serum uric acid levels correlate with the severity and the mortality of primary pulmonary hypertension
    • Nagaya N., Uematsu M., Satoh T., et al. Serum uric acid levels correlate with the severity and the mortality of primary pulmonary hypertension. Am J Respir Crit Care Med 160 (1999) 487-492
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 487-492
    • Nagaya, N.1    Uematsu, M.2    Satoh, T.3
  • 99
    • 0042433550 scopus 로고    scopus 로고
    • Detectable serum cardiac troponin T as a marker of poor prognosis among patients with chronic precapillary pulmonary hypertension
    • Torbicki A., Kurzyna M., Kuca P., et al. Detectable serum cardiac troponin T as a marker of poor prognosis among patients with chronic precapillary pulmonary hypertension. Circulation 108 (2003) 844-848
    • (2003) Circulation , vol.108 , pp. 844-848
    • Torbicki, A.1    Kurzyna, M.2    Kuca, P.3
  • 100
    • 33748998458 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • McLaughlin V.V., and McGoon M.D. Pulmonary arterial hypertension. Circulation 114 (2006) 1417-1431
    • (2006) Circulation , vol.114 , pp. 1417-1431
    • McLaughlin, V.V.1    McGoon, M.D.2
  • 101
  • 102
    • 0022355748 scopus 로고
    • Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients
    • Currie P.J., Seward J.B., Chan K.L., et al. Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol 6 (1985) 750-756
    • (1985) J Am Coll Cardiol , vol.6 , pp. 750-756
    • Currie, P.J.1    Seward, J.B.2    Chan, K.L.3
  • 103
    • 0037446217 scopus 로고    scopus 로고
    • Frequency and severity of tricuspid regurgitation determined by Doppler echocardiography in primary pulmonary hypertension
    • A9
    • Hinderliter A.L., Willis P.W., Long W.A., et al. Frequency and severity of tricuspid regurgitation determined by Doppler echocardiography in primary pulmonary hypertension. Am J Cardiol 91 (2003) 1033-1037 A9
    • (2003) Am J Cardiol , vol.91 , pp. 1033-1037
    • Hinderliter, A.L.1    Willis, P.W.2    Long, W.A.3
  • 104
    • 64849084730 scopus 로고    scopus 로고
    • Lantheus Medical Imaging Accessed February 11, 2009
    • Lantheus Medical Imaging. Definity prescribing information (2008). http://www.definityimaging.com/prescribing_info.html Accessed February 11, 2009
    • (2008) Definity prescribing information
  • 105
    • 2442643903 scopus 로고    scopus 로고
    • Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism
    • Pengo V., Lensing A.W., Prins M.H., et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. N Engl J Med 350 (2004) 2257-2264
    • (2004) N Engl J Med , vol.350 , pp. 2257-2264
    • Pengo, V.1    Lensing, A.W.2    Prins, M.H.3
  • 106
    • 33646196216 scopus 로고    scopus 로고
    • Chronic thromboembolic pulmonary hypertension
    • Hoeper M.M., Mayer E., Simonneau G., et al. Chronic thromboembolic pulmonary hypertension. Circulation 113 (2006) 2011-2020
    • (2006) Circulation , vol.113 , pp. 2011-2020
    • Hoeper, M.M.1    Mayer, E.2    Simonneau, G.3
  • 107
    • 10044258461 scopus 로고    scopus 로고
    • Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology
    • Galie N., Torbicki A., Barst R., et al. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology. Eur Heart J 25 (2004) 2243-2278
    • (2004) Eur Heart J , vol.25 , pp. 2243-2278
    • Galie, N.1    Torbicki, A.2    Barst, R.3
  • 108
    • 4143129168 scopus 로고    scopus 로고
    • Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • Rubin L.J. Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 7S-10S
    • (2004) Chest , vol.126
    • Rubin, L.J.1
  • 109
    • 0032814424 scopus 로고    scopus 로고
    • Determination of cardiac output by the Fick method, thermodilution, and acetylene rebreathing in pulmonary hypertension
    • Hoeper M.M., Maier R., Tongers J., et al. Determination of cardiac output by the Fick method, thermodilution, and acetylene rebreathing in pulmonary hypertension. Am J Respir Crit Care Med 160 (1999) 535-541
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 535-541
    • Hoeper, M.M.1    Maier, R.2    Tongers, J.3
  • 110
    • 33845343982 scopus 로고    scopus 로고
    • Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers
    • Hoeper M.M., Lee S.H., Voswinckel R., et al. Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol 48 (2006) 2546-2552
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2546-2552
    • Hoeper, M.M.1    Lee, S.H.2    Voswinckel, R.3
  • 111
    • 18844372029 scopus 로고    scopus 로고
    • Hemodynamic observations in two pulmonary hypertensive patients changing treatment from inhaled iloprost to the oral endothelin-antagonist bosentan
    • Fruhwald F.M., Kjellstrom B., Perthold W., et al. Hemodynamic observations in two pulmonary hypertensive patients changing treatment from inhaled iloprost to the oral endothelin-antagonist bosentan. J Heart Lung Transplant 24 (2005) 631-634
    • (2005) J Heart Lung Transplant , vol.24 , pp. 631-634
    • Fruhwald, F.M.1    Kjellstrom, B.2    Perthold, W.3
  • 112
    • 19344368674 scopus 로고    scopus 로고
    • Continuous haemodynamic monitoring during exercise in patients with pulmonary hypertension
    • Wonisch M., Fruhwald F.M., Maier R., et al. Continuous haemodynamic monitoring during exercise in patients with pulmonary hypertension. Int J Cardiol 101 (2005) 415-420
    • (2005) Int J Cardiol , vol.101 , pp. 415-420
    • Wonisch, M.1    Fruhwald, F.M.2    Maier, R.3
  • 113
    • 34447504020 scopus 로고    scopus 로고
    • Right ventricular pressure waveform and wave reflection analysis in patients with pulmonary arterial hypertension
    • Karamanoglu M., McGoon M., Frantz R.P., et al. Right ventricular pressure waveform and wave reflection analysis in patients with pulmonary arterial hypertension. Chest 132 (2007) 37-43
    • (2007) Chest , vol.132 , pp. 37-43
    • Karamanoglu, M.1    McGoon, M.2    Frantz, R.P.3
  • 114
    • 1342288852 scopus 로고    scopus 로고
    • Clinical value of vasodilator test with inhaled nitric oxide for predicting long-term response to oral vasodilators in pulmonary hypertension
    • Morales-Blanhir J., Santos S., de Jover L., et al. Clinical value of vasodilator test with inhaled nitric oxide for predicting long-term response to oral vasodilators in pulmonary hypertension. Respir Med 98 (2004) 225-234
    • (2004) Respir Med , vol.98 , pp. 225-234
    • Morales-Blanhir, J.1    Santos, S.2    de Jover, L.3
  • 115
    • 0026002659 scopus 로고
    • Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension
    • Pepke-Zaba J., Higenbottam T.W., Dinh'Xuan A.T., et al. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 338 (1991) 1173-1174
    • (1991) Lancet , vol.338 , pp. 1173-1174
    • Pepke-Zaba, J.1    Higenbottam, T.W.2    Dinh'Xuan, A.T.3
  • 116
    • 0019985926 scopus 로고
    • Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension
    • Rubin L.J., Groves B.M., Reeves J.T., et al. Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension. Circulation 66 (1982) 334-338
    • (1982) Circulation , vol.66 , pp. 334-338
    • Rubin, L.J.1    Groves, B.M.2    Reeves, J.T.3
  • 117
    • 0026519377 scopus 로고
    • Comparison of the effects of adenosine and nifedipine in pulmonary hypertension
    • Schrader B.J., Inbar S., Kaufmann L., et al. Comparison of the effects of adenosine and nifedipine in pulmonary hypertension. J Am Coll Cardiol 19 (1992) 1060-1064
    • (1992) J Am Coll Cardiol , vol.19 , pp. 1060-1064
    • Schrader, B.J.1    Inbar, S.2    Kaufmann, L.3
  • 118
    • 0024804879 scopus 로고
    • The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension
    • Weir E.K., Rubin L.J., Ayres S.M., et al. The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension. Am Rev Respir Dis 140 (1989) 1623-1630
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1623-1630
    • Weir, E.K.1    Rubin, L.J.2    Ayres, S.M.3
  • 119
    • 34250870730 scopus 로고    scopus 로고
    • Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines
    • Badesch D.B., Abman S.H., Simonneau G., et al. Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest 131 (2007) 1917-1928
    • (2007) Chest , vol.131 , pp. 1917-1928
    • Badesch, D.B.1    Abman, S.H.2    Simonneau, G.3
  • 120
    • 33745125419 scopus 로고    scopus 로고
    • Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension
    • Elliott C.G., Glissmeyer E.W., Havlena G.T., et al. Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension. Circulation 113 (2006) 2509-2515
    • (2006) Circulation , vol.113 , pp. 2509-2515
    • Elliott, C.G.1    Glissmeyer, E.W.2    Havlena, G.T.3
  • 121
    • 0031718736 scopus 로고    scopus 로고
    • Primary pulmonary hypertension associated with the use of fenfluramine derivatives
    • Simonneau G., Fartoukh M., Sitbon O., et al. Primary pulmonary hypertension associated with the use of fenfluramine derivatives. Chest 114 (1998) 195S-199S
    • (1998) Chest , vol.114
    • Simonneau, G.1    Fartoukh, M.2    Sitbon, O.3
  • 122
    • 0033512182 scopus 로고    scopus 로고
    • Systemic sclerosis-associated pulmonary hypertension: short- and long-term effects of epoprostenol (prostacyclin)
    • Klings E.S., Hill N.S., Ieong M.H., et al. Systemic sclerosis-associated pulmonary hypertension: short- and long-term effects of epoprostenol (prostacyclin). Arthritis Rheum 42 (1999) 2638-2645
    • (1999) Arthritis Rheum , vol.42 , pp. 2638-2645
    • Klings, E.S.1    Hill, N.S.2    Ieong, M.H.3
  • 123
    • 0028277867 scopus 로고
    • Inhaled nitric oxide leading to pulmonary edema in stable severe heart failure
    • Bocchi E.A., Bacal F., Auler Junior J.O., et al. Inhaled nitric oxide leading to pulmonary edema in stable severe heart failure. Am J Cardiol 74 (1994) 70-72
    • (1994) Am J Cardiol , vol.74 , pp. 70-72
    • Bocchi, E.A.1    Bacal, F.2    Auler Junior, J.O.3
  • 124
    • 2942544581 scopus 로고    scopus 로고
    • Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension
    • Galie N., Seeger W., Naeije R., et al. Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 43 (2004) 81S-88S
    • (2004) J Am Coll Cardiol , vol.43
    • Galie, N.1    Seeger, W.2    Naeije, R.3
  • 125
    • 33749525364 scopus 로고    scopus 로고
    • Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension
    • Mereles D., Ehlken N., Kreuscher S., et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation 114 (2006) 1482-1489
    • (2006) Circulation , vol.114 , pp. 1482-1489
    • Mereles, D.1    Ehlken, N.2    Kreuscher, S.3
  • 126
    • 38349027064 scopus 로고    scopus 로고
    • Hypoxia during air travel in adults with pulmonary disease
    • Mohr L.C. Hypoxia during air travel in adults with pulmonary disease. Am J Med Sci 335 (2008) 71-79
    • (2008) Am J Med Sci , vol.335 , pp. 71-79
    • Mohr, L.C.1
  • 127
    • 0031747446 scopus 로고    scopus 로고
    • Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996
    • Weiss B.M., Zemp L., Seifert B., et al. Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996. J Am Coll Cardiol 31 (1998) 1650-1657
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1650-1657
    • Weiss, B.M.1    Zemp, L.2    Seifert, B.3
  • 128
    • 0021193273 scopus 로고
    • Primary pulmonary hypertension: natural history and the importance of thrombosis
    • Fuster V., Steele P.M., Edwards W.D., et al. Primary pulmonary hypertension: natural history and the importance of thrombosis. Circulation 70 (1984) 580-587
    • (1984) Circulation , vol.70 , pp. 580-587
    • Fuster, V.1    Steele, P.M.2    Edwards, W.D.3
  • 129
    • 0031719459 scopus 로고    scopus 로고
    • The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension
    • Rich S., Seidlitz M., Dodin E., et al. The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest 114 (1998) 787-792
    • (1998) Chest , vol.114 , pp. 787-792
    • Rich, S.1    Seidlitz, M.2    Dodin, E.3
  • 130
    • 0033679134 scopus 로고    scopus 로고
    • Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension
    • Aguilar R.V., and Farber H.W. Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension. Am J Respir Crit Care Med 162 (2000) 1846-1850
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1846-1850
    • Aguilar, R.V.1    Farber, H.W.2
  • 131
    • 0031041342 scopus 로고    scopus 로고
    • Continuous intravenous infusion of epoprostenol for the treatment of portopulmonary hypertension
    • Kuo P.C., Johnson L.B., Plotkin J.S., et al. Continuous intravenous infusion of epoprostenol for the treatment of portopulmonary hypertension. Transplantation 63 (1997) 604-606
    • (1997) Transplantation , vol.63 , pp. 604-606
    • Kuo, P.C.1    Johnson, L.B.2    Plotkin, J.S.3
  • 132
    • 0033522395 scopus 로고    scopus 로고
    • Compassionate use of continuous prostacyclin in the management of secondary pulmonary hypertension: a case series
    • McLaughlin V.V., Genthner D.E., Panella M.M., et al. Compassionate use of continuous prostacyclin in the management of secondary pulmonary hypertension: a case series. Ann Intern Med 130 (1999) 740-743
    • (1999) Ann Intern Med , vol.130 , pp. 740-743
    • McLaughlin, V.V.1    Genthner, D.E.2    Panella, M.M.3
  • 133
    • 0037687432 scopus 로고    scopus 로고
    • Prognostic factors for survival in human immunodeficiency virus-associated pulmonary arterial hypertension
    • Nunes H., Humbert M., Sitbon O., et al. Prognostic factors for survival in human immunodeficiency virus-associated pulmonary arterial hypertension. Am J Respir Crit Care Med 167 (2003) 1433-1439
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1433-1439
    • Nunes, H.1    Humbert, M.2    Sitbon, O.3
  • 134
    • 0033213243 scopus 로고    scopus 로고
    • The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension
    • Rich S., and McLaughlin V.V. The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension. J Am Coll Cardiol 34 (1999) 1184-1187
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1184-1187
    • Rich, S.1    McLaughlin, V.V.2
  • 135
    • 3242786431 scopus 로고    scopus 로고
    • Pharmacokinetics and steady-state bioequivalence of treprostinil sodium (Remodulin) administered by the intravenous and subcutaneous route to normal volunteers
    • Laliberte K., Arneson C., Jeffs R., et al. Pharmacokinetics and steady-state bioequivalence of treprostinil sodium (Remodulin) administered by the intravenous and subcutaneous route to normal volunteers. J Cardiovasc Pharmacol 44 (2004) 209-214
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 209-214
    • Laliberte, K.1    Arneson, C.2    Jeffs, R.3
  • 136
    • 0037086133 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial
    • Simonneau G., Barst R.J., Galie N., et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 165 (2002) 800-804
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 800-804
    • Simonneau, G.1    Barst, R.J.2    Galie, N.3
  • 137
    • 33645119109 scopus 로고    scopus 로고
    • Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial
    • Tapson V.F., Gomberg-Maitland M., McLaughlin V.V., et al. Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial. Chest 129 (2006) 683-688
    • (2006) Chest , vol.129 , pp. 683-688
    • Tapson, V.F.1    Gomberg-Maitland, M.2    McLaughlin, V.V.3
  • 138
    • 30444458863 scopus 로고    scopus 로고
    • Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension
    • Gomberg-Maitland M., Tapson V.F., Benza R.L., et al. Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension. Am J Respir Crit Care Med 172 (2005) 1586-1589
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1586-1589
    • Gomberg-Maitland, M.1    Tapson, V.F.2    Benza, R.L.3
  • 139
    • 33847739748 scopus 로고    scopus 로고
    • Bloodstream infections among patients treated with intravenous epoprostenol or intravenous treprostinil for pulmonary arterial hypertension-seven sites, United States, 2003-2006
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Bloodstream infections among patients treated with intravenous epoprostenol or intravenous treprostinil for pulmonary arterial hypertension-seven sites, United States, 2003-2006. MMWR Morb Mortal Wkly Rep 56 (2007) 170-172
    • (2007) MMWR Morb Mortal Wkly Rep , vol.56 , pp. 170-172
  • 140
    • 64849115968 scopus 로고    scopus 로고
    • Guidelines for the prevention of central venous catheter-related bloodstream infections with prostanoid therapy for pulmonary arterial hypertension
    • Doran A., Ivy D., Barst R.J., et al. Guidelines for the prevention of central venous catheter-related bloodstream infections with prostanoid therapy for pulmonary arterial hypertension. Adv Pulm Hypertens 7 (2008) 245-248
    • (2008) Adv Pulm Hypertens , vol.7 , pp. 245-248
    • Doran, A.1    Ivy, D.2    Barst, R.J.3
  • 141
    • 0036682273 scopus 로고    scopus 로고
    • Inhaled iloprost for severe pulmonary hypertension
    • Olschewski H., Simonneau G., Galie N., et al. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 347 (2002) 322-329
    • (2002) N Engl J Med , vol.347 , pp. 322-329
    • Olschewski, H.1    Simonneau, G.2    Galie, N.3
  • 142
    • 0034702248 scopus 로고    scopus 로고
    • Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue
    • Hoeper M.M., Schwarze M., Ehlerding S., et al. Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue. N Engl J Med 342 (2000) 1866-1870
    • (2000) N Engl J Med , vol.342 , pp. 1866-1870
    • Hoeper, M.M.1    Schwarze, M.2    Ehlerding, S.3
  • 143
    • 21544449424 scopus 로고    scopus 로고
    • Clinical efficacy and survival with first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension
    • Opitz C.F., Wensel R., Winkler J., et al. Clinical efficacy and survival with first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension. Eur Heart J 26 (2005) 1895-1902
    • (2005) Eur Heart J , vol.26 , pp. 1895-1902
    • Opitz, C.F.1    Wensel, R.2    Winkler, J.3
  • 144
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
    • Channick R.N., Simonneau G., Sitbon O., et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 358 (2001) 1119-1123
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3
  • 145
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Rubin L.J., Badesch D.B., Barst R.J., et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 346 (2002) 896-903
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 146
    • 33645243403 scopus 로고    scopus 로고
    • Long-term outcome with first-line bosentan therapy in idiopathic pulmonary arterial hypertension
    • Provencher S., Sitbon O., Humbert M., et al. Long-term outcome with first-line bosentan therapy in idiopathic pulmonary arterial hypertension. Eur Heart J 27 (2006) 589-595
    • (2006) Eur Heart J , vol.27 , pp. 589-595
    • Provencher, S.1    Sitbon, O.2    Humbert, M.3
  • 147
    • 27744444638 scopus 로고    scopus 로고
    • Survival in patients with class III idiopathic pulmonary arterial hypertension treated with first line oral bosentan compared with an historical cohort of patients started on intravenous epoprostenol
    • Sitbon O., McLaughlin V.V., Badesch D.B., et al. Survival in patients with class III idiopathic pulmonary arterial hypertension treated with first line oral bosentan compared with an historical cohort of patients started on intravenous epoprostenol. Thorax 60 (2005) 1025-1030
    • (2005) Thorax , vol.60 , pp. 1025-1030
    • Sitbon, O.1    McLaughlin, V.V.2    Badesch, D.B.3
  • 148
    • 33746206340 scopus 로고    scopus 로고
    • Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study
    • Galie N., Beghetti M., Gatzoulis M.A., et al. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 114 (2006) 48-54
    • (2006) Circulation , vol.114 , pp. 48-54
    • Galie, N.1    Beghetti, M.2    Gatzoulis, M.A.3
  • 149
    • 57449103127 scopus 로고    scopus 로고
    • Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFit (Bosentan Effects in iNopErable Forms of chronic Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
    • Jais X., D'Armini A.M., Jansa P., et al. Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFit (Bosentan Effects in iNopErable Forms of chronic Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial. J Am Coll Cardiol 52 (2008) 2127-2134
    • (2008) J Am Coll Cardiol , vol.52 , pp. 2127-2134
    • Jais, X.1    D'Armini, A.M.2    Jansa, P.3
  • 150
    • 9644302310 scopus 로고    scopus 로고
    • Bosentan for the treatment of human immunodeficiency virus-associated pulmonary arterial hypertension
    • Sitbon O., Gressin V., Speich R., et al. Bosentan for the treatment of human immunodeficiency virus-associated pulmonary arterial hypertension. Am J Respir Crit Care Med 170 (2004) 1212-1217
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1212-1217
    • Sitbon, O.1    Gressin, V.2    Speich, R.3
  • 151
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
    • Galie N., Rubin L., Hoeper M., et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 371 (2008) 2093-2100
    • (2008) Lancet , vol.371 , pp. 2093-2100
    • Galie, N.1    Rubin, L.2    Hoeper, M.3
  • 152
    • 10744230817 scopus 로고    scopus 로고
    • Sitaxsentan therapy for pulmonary arterial hypertension
    • Barst R.J., Langleben D., Frost A., et al. Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med 169 (2004) 441-447
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 441-447
    • Barst, R.J.1    Langleben, D.2    Frost, A.3
  • 153
    • 0036283401 scopus 로고    scopus 로고
    • Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with pulmonary arterial hypertension: open-label pilot study
    • Barst R.J., Rich S., Widlitz A., et al. Clinical efficacy of sitaxsentan, an endothelin-A receptor antagonist, in patients with
    • (2002) Chest , vol.121 , pp. 1860-1868
    • Barst, R.J.1    Rich, S.2    Widlitz, A.3
  • 154
    • 22844436819 scopus 로고    scopus 로고
    • Ambrisentan therapy for pulmonary arterial hypertension
    • Galie N., Badesch D., Oudiz R., et al. Ambrisentan therapy for pulmonary arterial hypertension. J Am Coll Cardiol 46 (2005) 529-535
    • (2005) J Am Coll Cardiol , vol.46 , pp. 529-535
    • Galie, N.1    Badesch, D.2    Oudiz, R.3
  • 155
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan for the treatment of pulmonary arterial hypertension: results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) study 1 and 2
    • (abstr)
    • Galie N., Olschewski H., Oudiz R.J., et al. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) study 1 and 2. (abstr). Circulation 117 (2008) 3010-3019
    • (2008) Circulation , vol.117 , pp. 3010-3019
    • Galie, N.1    Olschewski, H.2    Oudiz, R.J.3
  • 156
    • 67650616034 scopus 로고    scopus 로고
    • Gilead Accessed February 11, 2009
    • Gilead. Letairis full prescribing information (2008). http://www.letairis.com/full_prescribing_information.html Accessed February 11, 2009
    • (2008) Letairis full prescribing information
  • 157
    • 26444534291 scopus 로고    scopus 로고
    • Sildenafil citrate therapy for pulmonary arterial hypertension
    • Galie N., Ghofrani H.A., Torbicki A., et al. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 353 (2005) 2148-2157
    • (2005) N Engl J Med , vol.353 , pp. 2148-2157
    • Galie, N.1    Ghofrani, H.A.2    Torbicki, A.3
  • 158
    • 33644826152 scopus 로고    scopus 로고
    • Sildenafil citrate therapy for pulmonary arterial hypertension
    • Hoeper M.M., and Welte T. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 354 (2006) 1091-1093
    • (2006) N Engl J Med , vol.354 , pp. 1091-1093
    • Hoeper, M.M.1    Welte, T.2
  • 159
    • 4544383466 scopus 로고    scopus 로고
    • Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
    • Humbert M., Barst R.J., Robbins I.M., et al. Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. Eur Respir J 24 (2004) 353-359
    • (2004) Eur Respir J , vol.24 , pp. 353-359
    • Humbert, M.1    Barst, R.J.2    Robbins, I.M.3
  • 160
    • 33845526777 scopus 로고    scopus 로고
    • Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
    • McLaughlin V.V., Oudiz R.J., Frost A., et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 174 (2006) 1257-1263
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1257-1263
    • McLaughlin, V.V.1    Oudiz, R.J.2    Frost, A.3
  • 161
    • 33847368988 scopus 로고    scopus 로고
    • Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
    • Hoeper M.M., Leuchte H., Halank M., et al. Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 28 (2006) 691-694
    • (2006) Eur Respir J , vol.28 , pp. 691-694
    • Hoeper, M.M.1    Leuchte, H.2    Halank, M.3
  • 162
    • 54549125950 scopus 로고    scopus 로고
    • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial
    • Simonneau G., Rubin L.J., Galie N., et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 149 (2008) 521-530
    • (2008) Ann Intern Med , vol.149 , pp. 521-530
    • Simonneau, G.1    Rubin, L.J.2    Galie, N.3
  • 163
    • 34249302372 scopus 로고    scopus 로고
    • A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology
    • Macchia A., Marchioli R., Marfisi R., et al. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J 153 (2007) 1037-1047
    • (2007) Am Heart J , vol.153 , pp. 1037-1047
    • Macchia, A.1    Marchioli, R.2    Marfisi, R.3
  • 164
    • 62749192201 scopus 로고    scopus 로고
    • A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
    • Galie N., Manes A., Negro L., et al. A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J 30 (2009) 394-403
    • (2009) Eur Heart J , vol.30 , pp. 394-403
    • Galie, N.1    Manes, A.2    Negro, L.3
  • 165
    • 45149083080 scopus 로고    scopus 로고
    • Effects of oral treatments on exercise capacity in systemic sclerosis related pulmonary arterial hypertension: a meta-analysis of randomised controlled trials
    • Avouac J., Wipff J., Kahan A., et al. Effects of oral treatments on exercise capacity in systemic sclerosis related pulmonary arterial hypertension: a meta-analysis of randomised controlled trials. Ann Rheum Dis 67 (2008) 808-814
    • (2008) Ann Rheum Dis , vol.67 , pp. 808-814
    • Avouac, J.1    Wipff, J.2    Kahan, A.3
  • 166
    • 35748975442 scopus 로고    scopus 로고
    • Ambrisentan (Letairis) for pulmonary arterial hypertension
    • Ambrisentan (Letairis) for pulmonary arterial hypertension. Med Lett Drugs Ther 49 (2007) 87-88
    • (2007) Med Lett Drugs Ther , vol.49 , pp. 87-88
  • 167
    • 3142724657 scopus 로고    scopus 로고
    • Surgical treatments/interventions for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • Doyle R.L., McCrory D., Channick R.N., et al. Surgical treatments/interventions for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 63S-71S
    • (2004) Chest , vol.126
    • Doyle, R.L.1    McCrory, D.2    Channick, R.N.3
  • 168
    • 2942541465 scopus 로고    scopus 로고
    • Interventional and surgical modalities of treatment for pulmonary arterial hypertension
    • Klepetko W., Mayer E., Sandoval J., et al. Interventional and surgical modalities of treatment for pulmonary arterial hypertension. J Am Coll Cardiol 43 (2004) 73S-80S
    • (2004) J Am Coll Cardiol , vol.43
    • Klepetko, W.1    Mayer, E.2    Sandoval, J.3
  • 169
    • 24644464697 scopus 로고    scopus 로고
    • Surgical and interventional therapies for pulmonary arterial hypertension
    • Olsson J.K., Zamanian R.T., Feinstein J.A., et al. Surgical and interventional therapies for pulmonary arterial hypertension. Semin Respir Crit Care Med 26 (2005) 417-428
    • (2005) Semin Respir Crit Care Med , vol.26 , pp. 417-428
    • Olsson, J.K.1    Zamanian, R.T.2    Feinstein, J.A.3
  • 170
    • 0041829193 scopus 로고    scopus 로고
    • Atrial septostomy in the treatment of severe pulmonary arterial hypertension
    • Reichenberger F., Pepke-Zaba J., McNeil K., et al. Atrial septostomy in the treatment of severe pulmonary arterial hypertension. Thorax 58 (2003) 797-800
    • (2003) Thorax , vol.58 , pp. 797-800
    • Reichenberger, F.1    Pepke-Zaba, J.2    McNeil, K.3
  • 171
    • 0033568512 scopus 로고    scopus 로고
    • Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension
    • Rothman A., Sklansky M.S., Lucas V.W., et al. Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension. Am J Cardiol 84 (1999) 682-686
    • (1999) Am J Cardiol , vol.84 , pp. 682-686
    • Rothman, A.1    Sklansky, M.S.2    Lucas, V.W.3
  • 172
    • 0032145492 scopus 로고    scopus 로고
    • Graded balloon dilation atrial septostomy in severe primary pulmonary hypertension. A therapeutic alternative for patients nonresponsive to vasodilator treatment
    • Sandoval J., Gaspar J., Pulido T., et al. Graded balloon dilation atrial septostomy in severe primary pulmonary hypertension. A therapeutic alternative for patients nonresponsive to vasodilator treatment. J Am Coll Cardiol 32 (1998) 297-304
    • (1998) J Am Coll Cardiol , vol.32 , pp. 297-304
    • Sandoval, J.1    Gaspar, J.2    Pulido, T.3
  • 173
    • 33746385493 scopus 로고    scopus 로고
    • Insertion of a fenestrated Amplatzer atrial septostomy device for severe pulmonary hypertension
    • O'Loughlin A.J., Keogh A., and Muller D.W. Insertion of a fenestrated Amplatzer atrial septostomy device for severe pulmonary hypertension. Heart Lung Circ 15 (2006) 275-277
    • (2006) Heart Lung Circ , vol.15 , pp. 275-277
    • O'Loughlin, A.J.1    Keogh, A.2    Muller, D.W.3
  • 174
    • 0035070836 scopus 로고    scopus 로고
    • Balloon atrial septostomy in end-stage pulmonary hypertension guided by a novel intracardiac echocardiographic transducer
    • Moscucci M., Dairywala I.T., Chetcuti S., et al. Balloon atrial septostomy in end-stage pulmonary hypertension guided by a novel intracardiac echocardiographic transducer. Catheter Cardiovasc Interv 52 (2001) 530-534
    • (2001) Catheter Cardiovasc Interv , vol.52 , pp. 530-534
    • Moscucci, M.1    Dairywala, I.T.2    Chetcuti, S.3
  • 175
    • 33746520676 scopus 로고    scopus 로고
    • Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult lung and heart-lung transplantation report-2006
    • Trulock E.P., Edwards L.B., Taylor D.O., et al. Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult lung and heart-lung transplantation report-2006. J Heart Lung Transplant 25 (2006) 880-892
    • (2006) J Heart Lung Transplant , vol.25 , pp. 880-892
    • Trulock, E.P.1    Edwards, L.B.2    Taylor, D.O.3
  • 176
    • 64849083095 scopus 로고    scopus 로고
    • Deleted in proof
    • Deleted in proof.
  • 177
    • 33645107927 scopus 로고    scopus 로고
    • Risk factors for reperfusion injury after lung transplantation
    • Cottini S.R., Lerch N., de Perrot M., et al. Risk factors for reperfusion injury after lung transplantation. Intensive Care Med 32 (2006) 557-563
    • (2006) Intensive Care Med , vol.32 , pp. 557-563
    • Cottini, S.R.1    Lerch, N.2    de Perrot, M.3
  • 178
    • 14644439867 scopus 로고    scopus 로고
    • Repair of congenital heart lesions combined with lung transplantation for the treatment of severe pulmonary hypertension: a 13-year experience
    • Choong C.K., Sweet S.C., Guthrie T.J., et al. Repair of congenital heart lesions combined with lung transplantation for the treatment of severe pulmonary hypertension: a 13-year experience. J Thorac Cardiovasc Surg 129 (2005) 661-669
    • (2005) J Thorac Cardiovasc Surg , vol.129 , pp. 661-669
    • Choong, C.K.1    Sweet, S.C.2    Guthrie, T.J.3
  • 179
    • 4544361900 scopus 로고    scopus 로고
    • Biventricular support with the Jarvik 2000 ventricular assist device in a calf model of pulmonary hypertension
    • Kindo M., Radovancevic B., Gregoric I.D., et al. Biventricular support with the Jarvik 2000 ventricular assist device in a calf model of pulmonary hypertension. ASAIO J 50 (2004) 444-450
    • (2004) ASAIO J , vol.50 , pp. 444-450
    • Kindo, M.1    Radovancevic, B.2    Gregoric, I.D.3
  • 180
  • 181
    • 0030853952 scopus 로고    scopus 로고
    • A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: the Flolan International Randomized Survival Trial (FIRST)
    • Califf R.M., Adams K.F., McKenna W.J., et al. A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: the Flolan International Randomized Survival Trial (FIRST). Am Heart J 134 (1997) 44-54
    • (1997) Am Heart J , vol.134 , pp. 44-54
    • Califf, R.M.1    Adams, K.F.2    McKenna, W.J.3
  • 182
    • 0037392105 scopus 로고    scopus 로고
    • First experiences with the stable prostacyclin analog iloprost in the evaluation of heart transplant candidates with increased pulmonary vascular resistance
    • Sablotzki A., Czeslick E., Gruenig E., et al. First experiences with the stable prostacyclin analog iloprost in the evaluation of heart transplant candidates with increased pulmonary vascular resistance. J Thorac Cardiovasc Surg 125 (2003) 960-962
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 960-962
    • Sablotzki, A.1    Czeslick, E.2    Gruenig, E.3
  • 183
    • 1642494802 scopus 로고    scopus 로고
    • Endothelin expression and the progression of heart failure: exemplifying the vagaries of therapeutic development
    • Konstam M.A., and DeNofrio D. Endothelin expression and the progression of heart failure: exemplifying the vagaries of therapeutic development. Circulation 109 (2004) 143-145
    • (2004) Circulation , vol.109 , pp. 143-145
    • Konstam, M.A.1    DeNofrio, D.2
  • 184
    • 0032564374 scopus 로고    scopus 로고
    • Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure
    • Sutsch G., Kiowski W., Yan X.W., et al. Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure. Circulation 98 (1998) 2262-2268
    • (1998) Circulation , vol.98 , pp. 2262-2268
    • Sutsch, G.1    Kiowski, W.2    Yan, X.W.3
  • 185
    • 0033510665 scopus 로고    scopus 로고
    • Update of REACH-1 and MERIT-HF clinical trials in heart failure
    • Cardio.net Editorial Team
    • Mylona P., and Cleland J.G. Update of REACH-1 and MERIT-HF clinical trials in heart failure. Cardio.net Editorial Team. Eur J Heart Fail 1 (1999) 197-200
    • (1999) Eur J Heart Fail , vol.1 , pp. 197-200
    • Mylona, P.1    Cleland, J.G.2
  • 186
    • 0036023198 scopus 로고    scopus 로고
    • Recent heart failure trials of neurohormonal modulation (OVERTURE and ENABLE): approaching the asymptote of efficacy?
    • Teerlink J.R. Recent heart failure trials of neurohormonal modulation (OVERTURE and ENABLE): approaching the asymptote of efficacy?. J Card Fail 8 (2002) 124-127
    • (2002) J Card Fail , vol.8 , pp. 124-127
    • Teerlink, J.R.1
  • 187
    • 33646048276 scopus 로고    scopus 로고
    • Initial experience with bosentan therapy in patients considered ineligible for heart transplantation because of severe pulmonary hypertension
    • Perez-Villa F., Cuppoletti A., Rossel V., et al. Initial experience with bosentan therapy in patients considered ineligible for heart transplantation because of severe pulmonary hypertension. Clin Transplant 20 (2006) 239-244
    • (2006) Clin Transplant , vol.20 , pp. 239-244
    • Perez-Villa, F.1    Cuppoletti, A.2    Rossel, V.3
  • 188
    • 20444420506 scopus 로고    scopus 로고
    • Severe left ventricular dysfunction secondary to primary pulmonary hypertension: bridging therapy with bosentan before lung transplantation
    • Brauchlin A.E., Soccal P.M., Rochat T., et al. Severe left ventricular dysfunction secondary to primary pulmonary hypertension: bridging therapy with bosentan before lung transplantation. J Heart Lung Transplant 24 (2005) 777-780
    • (2005) J Heart Lung Transplant , vol.24 , pp. 777-780
    • Brauchlin, A.E.1    Soccal, P.M.2    Rochat, T.3
  • 189
    • 9344264600 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil in the evaluation of pulmonary hypertension in severe heart failure
    • Alaeddini J., Uber P.A., Park M.H., et al. Efficacy and safety of sildenafil in the evaluation of pulmonary hypertension in severe heart failure. Am J Cardiol 94 (2004) 1475-1477
    • (2004) Am J Cardiol , vol.94 , pp. 1475-1477
    • Alaeddini, J.1    Uber, P.A.2    Park, M.H.3
  • 190
    • 19844361803 scopus 로고    scopus 로고
    • Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide
    • Lepore J.J., Maroo A., Bigatello L.M., et al. Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide. Chest 127 (2005) 1647-1653
    • (2005) Chest , vol.127 , pp. 1647-1653
    • Lepore, J.J.1    Maroo, A.2    Bigatello, L.M.3
  • 191
    • 33846099444 scopus 로고    scopus 로고
    • Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure
    • Lewis G.D., Lachmann J., Camuso J., et al. Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation 115 (2007) 59-66
    • (2007) Circulation , vol.115 , pp. 59-66
    • Lewis, G.D.1    Lachmann, J.2    Camuso, J.3
  • 192
    • 34848914106 scopus 로고    scopus 로고
    • Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension
    • Lewis G.D., Shah R., Shahzad K., et al. Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension. Circulation 116 (2007) 1555-1562
    • (2007) Circulation , vol.116 , pp. 1555-1562
    • Lewis, G.D.1    Shah, R.2    Shahzad, K.3
  • 193
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle
    • Zile M.R., Baicu C.F., and Gaasch W.H. Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 350 (2004) 1953-1959
    • (2004) N Engl J Med , vol.350 , pp. 1953-1959
    • Zile, M.R.1    Baicu, C.F.2    Gaasch, W.H.3
  • 194
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial
    • Yusuf S., Pfeffer M.A., Swedberg K., et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet 362 (2003) 777-781
    • (2003) Lancet , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3
  • 195
    • 33646807764 scopus 로고    scopus 로고
    • Outcome of watchful waiting in asymptomatic severe mitral regurgitation
    • Rosenhek R., Rader F., Klaar U., et al. Outcome of watchful waiting in asymptomatic severe mitral regurgitation. Circulation 113 (2006) 2238-2244
    • (2006) Circulation , vol.113 , pp. 2238-2244
    • Rosenhek, R.1    Rader, F.2    Klaar, U.3
  • 196
    • 34250836735 scopus 로고    scopus 로고
    • ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists
    • Bonow R.O., Carabello B.A., Kanu C., et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol 48 (2006) e1-e149
    • (2006) J Am Coll Cardiol , vol.48
    • Bonow, R.O.1    Carabello, B.A.2    Kanu, C.3
  • 197
  • 198
    • 17644425321 scopus 로고    scopus 로고
    • Pulmonary hypertension and chronic obstructive pulmonary disease: a case for treatment
    • Higenbottam T. Pulmonary hypertension and chronic obstructive pulmonary disease: a case for treatment. Proc Am Thorac Soc 2 (2005) 12-19
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 12-19
    • Higenbottam, T.1
  • 199
    • 17644406055 scopus 로고    scopus 로고
    • Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease
    • Naeije R. Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2 (2005) 20-22
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 20-22
    • Naeije, R.1
  • 200
    • 0036683421 scopus 로고    scopus 로고
    • Hemodynamic characterization of patients with severe emphysema
    • Scharf S.M., Iqbal M., Keller C., et al. Hemodynamic characterization of patients with severe emphysema. Am J Respir Crit Care Med 166 (2002) 314-322
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 314-322
    • Scharf, S.M.1    Iqbal, M.2    Keller, C.3
  • 201
    • 22144433036 scopus 로고    scopus 로고
    • Severe pulmonary hypertension and chronic obstructive pulmonary disease
    • Chaouat A., Bugnet A.S., Kadaoui N., et al. Severe pulmonary hypertension and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 172 (2005) 189-194
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 189-194
    • Chaouat, A.1    Bugnet, A.S.2    Kadaoui, N.3
  • 202
    • 19844369633 scopus 로고    scopus 로고
    • Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation
    • Thabut G., Dauriat G., Stern J.B., et al. Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest 127 (2005) 1531-1536
    • (2005) Chest , vol.127 , pp. 1531-1536
    • Thabut, G.1    Dauriat, G.2    Stern, J.B.3
  • 203
    • 0142085751 scopus 로고    scopus 로고
    • Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease
    • Eddahibi S., Chaouat A., Morrell N., et al. Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease. Circulation 108 (2003) 1839-1844
    • (2003) Circulation , vol.108 , pp. 1839-1844
    • Eddahibi, S.1    Chaouat, A.2    Morrell, N.3
  • 204
    • 33747187234 scopus 로고    scopus 로고
    • Sildenafil improves hemodynamic parameters in COPD-an investigation of six patients
    • Alp S., Skrygan M., Schmidt W.E., et al. Sildenafil improves hemodynamic parameters in COPD-an investigation of six patients. Pulm Pharmacol Ther 19 (2006) 386-390
    • (2006) Pulm Pharmacol Ther , vol.19 , pp. 386-390
    • Alp, S.1    Skrygan, M.2    Schmidt, W.E.3
  • 205
    • 33646126486 scopus 로고    scopus 로고
    • A potential role for sildenafil in the management of pulmonary hypertension in patients with parenchymal lung disease
    • Madden B.P., Allenby M., Loke T.K., et al. A potential role for sildenafil in the management of pulmonary hypertension in patients with parenchymal lung disease. Vascul Pharmacol 44 (2006) 372-376
    • (2006) Vascul Pharmacol , vol.44 , pp. 372-376
    • Madden, B.P.1    Allenby, M.2    Loke, T.K.3
  • 206
    • 0037361987 scopus 로고    scopus 로고
    • Advances in the treatment of secondary pulmonary hypertension
    • Maloney J.P. Advances in the treatment of secondary pulmonary hypertension. Curr Opin Pulm Med 9 (2003) 139-143
    • (2003) Curr Opin Pulm Med , vol.9 , pp. 139-143
    • Maloney, J.P.1
  • 207
    • 33847386219 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with interstitial lung diseases
    • Ryu J.H., Krowka M.J., Pellikka P.A., et al. Pulmonary hypertension in patients with interstitial lung diseases. Mayo Clin Proc 82 (2007) 342-350
    • (2007) Mayo Clin Proc , vol.82 , pp. 342-350
    • Ryu, J.H.1    Krowka, M.J.2    Pellikka, P.A.3
  • 208
    • 33947406847 scopus 로고    scopus 로고
    • Pulmonary hypertension and pulmonary function testing in idiopathic pulmonary fibrosis
    • Nathan S.D., Shlobin O.A., Ahmad S., et al. Pulmonary hypertension and pulmonary function testing in idiopathic pulmonary fibrosis. Chest 131 (2007) 657-663
    • (2007) Chest , vol.131 , pp. 657-663
    • Nathan, S.D.1    Shlobin, O.A.2    Ahmad, S.3
  • 209
    • 0037364372 scopus 로고    scopus 로고
    • Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease
    • Arcasoy S.M., Christie J.D., Ferrari V.A., et al. Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease. Am J Respir Crit Care Med 167 (2003) 735-740
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 735-740
    • Arcasoy, S.M.1    Christie, J.D.2    Ferrari, V.A.3
  • 210
    • 3543046555 scopus 로고    scopus 로고
    • Brain natriuretic peptide and exercise capacity in lung fibrosis and pulmonary hypertension
    • Leuchte H.H., Neurohr C., Baumgartner R., et al. Brain natriuretic peptide and exercise capacity in lung fibrosis and pulmonary hypertension. Am J Respir Crit Care Med 170 (2004) 360-365
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 360-365
    • Leuchte, H.H.1    Neurohr, C.2    Baumgartner, R.3
  • 211
    • 18744381053 scopus 로고    scopus 로고
    • Pulmonary hypertension in advanced sarcoidosis: epidemiology and clinical characteristics
    • Shorr A.F., Helman D.L., Davies D.B., et al. Pulmonary hypertension in advanced sarcoidosis: epidemiology and clinical characteristics. Eur Respir J 25 (2005) 783-788
    • (2005) Eur Respir J , vol.25 , pp. 783-788
    • Shorr, A.F.1    Helman, D.L.2    Davies, D.B.3
  • 212
    • 33751255100 scopus 로고    scopus 로고
    • Sarcoidosis-associated pulmonary hypertension: outcome with long-term epoprostenol treatment
    • Fisher K.A., Serlin D.M., Wilson K.C., et al. Sarcoidosis-associated pulmonary hypertension: outcome with long-term epoprostenol treatment. Chest 130 (2006) 1481-1488
    • (2006) Chest , vol.130 , pp. 1481-1488
    • Fisher, K.A.1    Serlin, D.M.2    Wilson, K.C.3
  • 213
    • 3142666018 scopus 로고    scopus 로고
    • Pulmonary artery hypertension and sleep-disordered breathing: ACCP evidence-based clinical practice guidelines
    • Atwood Jr. C.W., McCrory D., Garcia J.G., et al. Pulmonary artery hypertension and sleep-disordered breathing: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 72S-77S
    • (2004) Chest , vol.126
    • Atwood Jr., C.W.1    McCrory, D.2    Garcia, J.G.3
  • 214
    • 0027465172 scopus 로고
    • Pulmonary vascular lesions occurring in patients with chronic major vessel thromboembolic pulmonary hypertension
    • Moser K.M., and Bloor C.M. Pulmonary vascular lesions occurring in patients with chronic major vessel thromboembolic pulmonary hypertension. Chest 103 (1993) 685-692
    • (1993) Chest , vol.103 , pp. 685-692
    • Moser, K.M.1    Bloor, C.M.2
  • 215
    • 20144369219 scopus 로고    scopus 로고
    • Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension
    • Bonderman D., Jakowitsch J., Adlbrecht C., et al. Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension. Thromb Haemost 93 (2005) 512-516
    • (2005) Thromb Haemost , vol.93 , pp. 512-516
    • Bonderman, D.1    Jakowitsch, J.2    Adlbrecht, C.3
  • 216
    • 0242721247 scopus 로고    scopus 로고
    • Pulmonary endarterectomy: experience and lessons learned in 1,500 cases
    • Jamieson S.W., Kapelanski D.P., Sakakibara N., et al. Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. Ann Thorac Surg 76 (2003) 1457-1462
    • (2003) Ann Thorac Surg , vol.76 , pp. 1457-1462
    • Jamieson, S.W.1    Kapelanski, D.P.2    Sakakibara, N.3
  • 217
    • 33748767420 scopus 로고    scopus 로고
    • Assessment of operability in chronic thromboembolic pulmonary hypertension
    • Kim N.H. Assessment of operability in chronic thromboembolic pulmonary hypertension. Proc Am Thorac Soc 3 (2006) 584-588
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 584-588
    • Kim, N.H.1
  • 218
    • 0035830404 scopus 로고    scopus 로고
    • Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension
    • Feinstein J.A., Goldhaber S.Z., Lock J.E., et al. Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension. Circulation 103 (2001) 10-13
    • (2001) Circulation , vol.103 , pp. 10-13
    • Feinstein, J.A.1    Goldhaber, S.Z.2    Lock, J.E.3
  • 219
    • 33748762790 scopus 로고    scopus 로고
    • Medical therapies for chronic thromboembolic pulmonary hypertension: an evolving treatment paradigm
    • Bresser P., Pepke-Zaba J., Jais X., et al. Medical therapies for chronic thromboembolic pulmonary hypertension: an evolving treatment paradigm. Proc Am Thorac Soc 3 (2006) 594-600
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 594-600
    • Bresser, P.1    Pepke-Zaba, J.2    Jais, X.3
  • 220
    • 0037331638 scopus 로고    scopus 로고
    • Epoprostenol therapy as a bridge to pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension
    • Kerr K.M., and Rubin L.J. Epoprostenol therapy as a bridge to pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Chest 123 (2003) 319-320
    • (2003) Chest , vol.123 , pp. 319-320
    • Kerr, K.M.1    Rubin, L.J.2
  • 221
    • 0037151691 scopus 로고    scopus 로고
    • Severe pulmonary hypertension in patients with severe aortic valve stenosis: clinical profile and prognostic implications
    • Malouf J.F., Enriquez-Sarano M., Pellikka P.A., et al. Severe pulmonary hypertension in patients with severe aortic valve stenosis: clinical profile and prognostic implications. J Am Coll Cardiol 40 (2002) 789-795
    • (2002) J Am Coll Cardiol , vol.40 , pp. 789-795
    • Malouf, J.F.1    Enriquez-Sarano, M.2    Pellikka, P.A.3
  • 222
    • 0028808648 scopus 로고
    • Long-term outcome of cardiac surgery in patients with mitral stenosis and severe pulmonary hypertension
    • Vincens J.J., Temizer D., Post J.R., et al. Long-term outcome of cardiac surgery in patients with mitral stenosis and severe pulmonary hypertension. Circulation 92 (1995) II137-II142
    • (1995) Circulation , vol.92
    • Vincens, J.J.1    Temizer, D.2    Post, J.R.3
  • 223
    • 33746351355 scopus 로고    scopus 로고
    • Preoperative pulmonary hypertension is associated with postoperative left ventricular dysfunction in chronic organic mitral regurgitation: an echocardiographic and hemodynamic study
    • Yang H., Davidson Jr. W.R., Chambers C.E., et al. Preoperative pulmonary hypertension is associated with postoperative left ventricular dysfunction in chronic organic mitral regurgitation: an echocardiographic and hemodynamic study. J Am Soc Echocardiogr 19 (2006) 1051-1055
    • (2006) J Am Soc Echocardiogr , vol.19 , pp. 1051-1055
    • Yang, H.1    Davidson Jr., W.R.2    Chambers, C.E.3
  • 224
    • 0026570626 scopus 로고
    • Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high risk group
    • Costard-Jackle A., and Fowler M.B. Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high risk group. J Am Coll Cardiol 19 (1992) 48-54
    • (1992) J Am Coll Cardiol , vol.19 , pp. 48-54
    • Costard-Jackle, A.1    Fowler, M.B.2
  • 225
    • 0029873835 scopus 로고    scopus 로고
    • As originally published in 1988: long-term results of mitral valve surgery in patients with severe pulmonary hypertension. Updated in 1996
    • Aris A., and Camara M.L. As originally published in 1988: long-term results of mitral valve surgery in patients with severe pulmonary hypertension. Updated in 1996. Ann Thorac Surg 61 (1996) 1583-1584
    • (1996) Ann Thorac Surg , vol.61 , pp. 1583-1584
    • Aris, A.1    Camara, M.L.2
  • 226
    • 0033778646 scopus 로고    scopus 로고
    • Effect of Inoue balloon mitral valvotomy on severe pulmonary arterial hypertension in 315 patients with rheumatic mitral stenosis: immediate and long-term results
    • Umesan C.V., Kapoor A., Sinha N., et al. Effect of Inoue balloon mitral valvotomy on severe pulmonary arterial hypertension in 315 patients with rheumatic mitral stenosis: immediate and long-term results. J Heart Valve Dis 9 (2000) 609-615
    • (2000) J Heart Valve Dis , vol.9 , pp. 609-615
    • Umesan, C.V.1    Kapoor, A.2    Sinha, N.3
  • 227
    • 0032007075 scopus 로고    scopus 로고
    • Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension
    • Argenziano M., Choudhri A.F., Moazami N., et al. Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. Ann Thorac Surg 65 (1998) 340-345
    • (1998) Ann Thorac Surg , vol.65 , pp. 340-345
    • Argenziano, M.1    Choudhri, A.F.2    Moazami, N.3
  • 228
    • 23744500095 scopus 로고    scopus 로고
    • Mild vs severe pulmonary hypertension before heart transplantation: different effects on posttransplantation pulmonary hypertension and mortality
    • Chang P.P., Longenecker J.C., Wang N.Y., et al. Mild vs severe pulmonary hypertension before heart transplantation: different effects on posttransplantation pulmonary hypertension and mortality. J Heart Lung Transplant 24 (2005) 998-1007
    • (2005) J Heart Lung Transplant , vol.24 , pp. 998-1007
    • Chang, P.P.1    Longenecker, J.C.2    Wang, N.Y.3
  • 229
    • 0032909610 scopus 로고    scopus 로고
    • Inhaled nitric oxide improves hemodynamics in patients with acute pulmonary hypertension after high-risk cardiac surgery
    • Beck J.R., Mongero L.B., Kroslowitz R.M., et al. Inhaled nitric oxide improves hemodynamics in patients with acute pulmonary hypertension after high-risk cardiac surgery. Perfusion 14 (1999) 37-42
    • (1999) Perfusion , vol.14 , pp. 37-42
    • Beck, J.R.1    Mongero, L.B.2    Kroslowitz, R.M.3
  • 230
    • 23244467096 scopus 로고    scopus 로고
    • Hemodynamic effects of inhaled nitric oxide and phosphodiesterase inhibitor (dipyridamole) on secondary pulmonary hypertension following heart valve surgery in adults
    • Santini F., Casali G., Franchi G., et al. Hemodynamic effects of inhaled nitric oxide and phosphodiesterase inhibitor (dipyridamole) on secondary pulmonary hypertension following heart valve surgery in adults. Int J Cardiol 103 (2005) 156-163
    • (2005) Int J Cardiol , vol.103 , pp. 156-163
    • Santini, F.1    Casali, G.2    Franchi, G.3
  • 231
    • 17644388812 scopus 로고    scopus 로고
    • Role of inhaled nitric oxide in adult heart or lung transplant recipients
    • Rea R.S., Ansani N.T., and Seybert A.L. Role of inhaled nitric oxide in adult heart or lung transplant recipients. Ann Pharmacother 39 (2005) 913-917
    • (2005) Ann Pharmacother , vol.39 , pp. 913-917
    • Rea, R.S.1    Ansani, N.T.2    Seybert, A.L.3
  • 232
    • 0036884496 scopus 로고    scopus 로고
    • Inhaled prostacyclin for the treatment of pulmonary hypertension after cardiac surgery
    • Lowson S.M., Doctor A., Walsh B.K., et al. Inhaled prostacyclin for the treatment of pulmonary hypertension after cardiac surgery. Crit Care Med 30 (2002) 2762-2764
    • (2002) Crit Care Med , vol.30 , pp. 2762-2764
    • Lowson, S.M.1    Doctor, A.2    Walsh, B.K.3
  • 233
    • 16244399842 scopus 로고    scopus 로고
    • Inhaled prostacyclin, nitric oxide, and nitroprusside in pulmonary hypertension after mitral valve replacement
    • Fattouch K., Sbraga F., Bianco G., et al. Inhaled prostacyclin, nitric oxide, and nitroprusside in pulmonary hypertension after mitral valve replacement. J Card Surg 20 (2005) 171-176
    • (2005) J Card Surg , vol.20 , pp. 171-176
    • Fattouch, K.1    Sbraga, F.2    Bianco, G.3
  • 234
    • 33750296514 scopus 로고    scopus 로고
    • Inhaled iloprost in eight heart transplant recipients presenting with post-bypass acute right ventricular dysfunction
    • Theodoraki K., Tsiapras D., Tsourelis L., et al. Inhaled iloprost in eight heart transplant recipients presenting with post-bypass acute right ventricular dysfunction. Acta Anaesthesiol Scand 50 (2006) 1213-1217
    • (2006) Acta Anaesthesiol Scand , vol.50 , pp. 1213-1217
    • Theodoraki, K.1    Tsiapras, D.2    Tsourelis, L.3
  • 235
    • 3242787267 scopus 로고    scopus 로고
    • Potential role for sildenafil in the management of perioperative pulmonary hypertension and right ventricular dysfunction after cardiac surgery
    • Madden B.P., Sheth A., Ho T.B., et al. Potential role for sildenafil in the management of perioperative pulmonary hypertension and right ventricular dysfunction after cardiac surgery. Br J Anaesth 93 (2004) 155-156
    • (2004) Br J Anaesth , vol.93 , pp. 155-156
    • Madden, B.P.1    Sheth, A.2    Ho, T.B.3
  • 236
    • 11144319974 scopus 로고    scopus 로고
    • Oral sildenafil reduces pulmonary hypertension after cardiac surgery
    • Trachte A.L., Lobato E.B., Urdaneta F., et al. Oral sildenafil reduces pulmonary hypertension after cardiac surgery. Ann Thorac Surg 79 (2005) 194-197
    • (2005) Ann Thorac Surg , vol.79 , pp. 194-197
    • Trachte, A.L.1    Lobato, E.B.2    Urdaneta, F.3
  • 237
    • 0032956980 scopus 로고    scopus 로고
    • Acute pulmonary hypertension after cardiopulmonary bypass in pig: the role of endogenous endothelin
    • Carteaux J.P., Roux S., Siaghy M., et al. Acute pulmonary hypertension after cardiopulmonary bypass in pig: the role of endogenous endothelin. Eur J Cardiothorac Surg 15 (1999) 346-352
    • (1999) Eur J Cardiothorac Surg , vol.15 , pp. 346-352
    • Carteaux, J.P.1    Roux, S.2    Siaghy, M.3
  • 238
    • 0022780559 scopus 로고
    • Proceedings of National Heart, Lung, and Blood Institute pediatric cardiology workshop: pulmonary hypertension
    • Friedman W.F. Proceedings of National Heart, Lung, and Blood Institute pediatric cardiology workshop: pulmonary hypertension. Pediatr Res 20 (1986) 811-824
    • (1986) Pediatr Res , vol.20 , pp. 811-824
    • Friedman, W.F.1
  • 239
    • 4544386270 scopus 로고    scopus 로고
    • BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease
    • Roberts K.E., McElroy J.J., Wong W.P., et al. BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease. Eur Respir J 24 (2004) 371-374
    • (2004) Eur Respir J , vol.24 , pp. 371-374
    • Roberts, K.E.1    McElroy, J.J.2    Wong, W.P.3
  • 240
    • 0033537630 scopus 로고    scopus 로고
    • Vasodilator therapy for primary pulmonary hypertension in children
    • Barst R.J., Maislin G., and Fishman A.P. Vasodilator therapy for primary pulmonary hypertension in children. Circulation 99 (1999) 1197-1208
    • (1999) Circulation , vol.99 , pp. 1197-1208
    • Barst, R.J.1    Maislin, G.2    Fishman, A.P.3
  • 241
    • 4043161231 scopus 로고    scopus 로고
    • Outcomes in children with idiopathic pulmonary arterial hypertension
    • Yung D., Widlitz A.C., Rosenzweig E.B., et al. Outcomes in children with idiopathic pulmonary arterial hypertension. Circulation 110 (2004) 660-665
    • (2004) Circulation , vol.110 , pp. 660-665
    • Yung, D.1    Widlitz, A.C.2    Rosenzweig, E.B.3
  • 242
    • 20344374050 scopus 로고    scopus 로고
    • Effects of long-term bosentan in children with pulmonary arterial hypertension
    • Rosenzweig E.B., Ivy D.D., Widlitz A., et al. Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol 46 (2005) 697-704
    • (2005) J Am Coll Cardiol , vol.46 , pp. 697-704
    • Rosenzweig, E.B.1    Ivy, D.D.2    Widlitz, A.3


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