Rapeseed oil fortified with micronutrients reduces atherosclerosis risk factors in rats fed a high-fat diet

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Xu, Jiqu ^a   Zhou, Xiaoqi ^b   Deng, Qianchun ^a   Huang, Qingde ^a   Yang, Jin'E ^a   Huang, Fenghong ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Atherosclerosis; Inflammation; Oxidant stress; Phytosterols; Plasma lipids; Polyphenols; Rapeseed oil; Tocopherols

Indexed keywords

ANTIOXIDANT; C REACTIVE PROTEIN; CATALASE; CHOLESTEROL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHYTOSTEROL; POLYPHENOL; RAPESEED OIL; SUPEROXIDE DISMUTASE; TOCOPHEROL; TRIACYLGLYCEROL; LIPID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRACE ELEMENT; VEGETABLE OIL;

ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; LIPID DIET; LIPID PEROXIDATION; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; SPRAGUE DAWLEY RAT; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; DRUG EFFECT; DRUG SCREENING; ENZYME ASSAY; FAT INTAKE; METABOLISM; RISK FACTOR;

BRASSICA NAPUS; RATTUS; RODENTIA;

ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; C-REACTIVE PROTEIN; CATALASE; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIETARY FATS; DRUG EVALUATION, PRECLINICAL; ENZYME ASSAYS; FOOD, FORTIFIED; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTERLEUKIN-6; LIPID PEROXIDATION; LIPIDS; MALE; MICRONUTRIENTS; PHYTOSTEROLS; PLANT OILS; POLYPHENOLS; RATS; RATS, SPRAGUE-DAWLEY; RISK FACTORS; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TOCOPHEROLS;

EID: 79958261934     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-96     Document Type: Article

References (44)

1. Oxidant stress and atherosclerosis. M Yokoyama, Curr Opin Pharmacol 2004 4 110 115 10.1016/j.coph.2003.12.004 15063353 (Pubitemid 38444044)
2. Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study. WP Castelli RJ Garrison PW Wilson RD Abbott S Kalousdian WB Kannel, JAMA 1986 256 2835 2838 10.1001/jama.256.20.2835 3773200 (Pubitemid 17178361)
3. Inflammation, atherosclerosis, and coronary artery disease. GK Hansson, N Engl J Med 2005 352 1685 1695 10.1056/NEJMra043430 15843671
4. Dietary modeling shows that the substitution of canola oil for fats commonly used in the United States would increase compliance with dietary recommendations for fatty acids. GH Johnson DR Keast PM Kris-Etherton, J Am Diet Assoc 2007 107 1726 1734 10.1016/j.jada.2007.07.015 17904932 (Pubitemid 47464107)
5. Elevated plasma fibrinogen caused by inadequate alpha-linolenic acid intake can be reduced by replacing fat with canola-type rapeseed oil. T Seppanen-Laakso I Laakso T Lehtimaki R Rontu E Moilanen T Solakivi L Seppo H Vanhanen K Kiviranta R Hiltunen, Prostaglandins Leukot Essent Fatty Acids 2010 83 45 54 10.1016/j.plefa.2010.02.001 20206485
6. Effects of dietary fatty acids on the composition and oxidizability of low-density lipoprotein. M Kratz P Cullen F Kannenberg A Kassner M Fobker PM Abuja G Assmann U Wahrburg, Eur J Clin Nutr 2002 56 72 81 10.1038/sj.ejcn. 1601288 11840183 (Pubitemid 34105555)
7. Effect of a rapeseed oil substituting diet on serum lipids and lipoproteins in children and adolescents with familial hypercholesterolemia. T Gulesserian K Widhalm, J Am Coll Nutr 2002 21 103 108 11999536 (Pubitemid 38639155)
8. Palm and partially hydrogenated soybean oils adversely alter lipoprotein profiles compared with soybean and canola oils in moderately hyperlipidemic subjects. S Vega-Lopez LM Ausman SM Jalbert AT Erkkila AH Lichtenstein, Am J Clin Nutr 2006 84 54 62 16825681 (Pubitemid 44699171)
9. Flavonoids from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation. CY Chen PE Milbury K Lapsley JB Blumberg, J Nutr 2005 135 1366 1373 15930439 (Pubitemid 40799597)
10. Effect of resveratrol, tyrosol and beta-sitosterol on oxidised low-density lipoprotein-stimulated oxidative stress, arachidonic acid release and prostaglandin E2 synthesis by RAW 264.7 macrophages. M Vivancos JJ Moreno, Br J Nutr 2008 99 1199 1207 18081942
11. Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome. S Devaraj S Leonard MG Traber I Jialal, Free Radic Biol Med 2008 44 1203 1208 10.1016/j.freeradbiomed.2007.12.018 18191645
12. Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans. RE Ostlund SB Racette A Okeke WF Stenson, Am J Clin Nutr 2002 75 1000 1004 12036805 (Pubitemid 34547528)
13. The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial. MI Covas K Nyyssonen HE Poulsen J Kaikkonen HJ Zunft H Kiesewetter A Gaddi R de la Torre J Mursu H Baumler S Nascetti JT Salonen M Fito J Virtanen J Marrugat Group ES, Ann Intern Med 2006 145 333 341 16954359 (Pubitemid 46768590)
14. Cardioprotective effects of dietary polyphenols. TL Zern ML Fernandez, J Nutr 2005 135 2291 2294 16177184 (Pubitemid 41429579)
15. Vitamin E, oxidative stress, and inflammation. U Singh S Devaraj I Jialal, Annu Rev Nutr 2005 25 151 174 10.1146/annurev.nutr.24.012003.132446 16011463 (Pubitemid 41208998)
16. The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years. PJ Bouic, Curr Opin Clin Nutr Metab Care 2001 4 471 475 10.1097/00075197-200111000-00001 11706278 (Pubitemid 34755401)
17. Micronutrient-enriched rapeseed oils reduce cardiovascular disease risk factors in rats fed a high-fat diet. L Attorri A Di Biase R Di Benedetto P Rigato A Di Virgilio S Salvati, Atherosclerosis 2010 213 422 428 10.1016/j.atherosclerosis.2010.07.003 20678771
18. Effect of adriamycin on the activities of superoxide dismutase, glutathione peroxidase and catalase in tissues of mice. Y Sazuka H Tanizawa Y Takino, Jpn J Cancer Res 1989 80 89 94 2496064 (Pubitemid 20027204)
19. A simple method for determination of serum catalase activity and revision of reference range. L Goth, Clin Chim Acta 1991 196 143 151 10.1016/0009-8981(91)90067-M 2029780
20. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Y Kono, Arch Biochem Biophys 1978 186 189 195 10.1016/0003-9861(78)90479-4 24422 (Pubitemid 8290500)
21. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. MS Moron JW Depierre B Mannervik, Biochim Biophys Acta 1979 582 67 78 760819 (Pubitemid 9065588)
22. Microsomal lipid peroxidation. JA Buege SD Aust, Methods Enzymol 1978 52 302 310 672633
23. The effect of vegetable oil-based cheese on serum total and lipoprotein lipids. HM Karvonen NS Tapola MI Uusitupa ES Sarkkinen, Eur J Clin Nutr 2002 56 1094 1101 10.1038/sj.ejcn.1601452 12428175 (Pubitemid 35414795)
24. Phytosterols and lecithin do not have an additive effect in lowering plasma and hepatic cholesterol levels in diet-induced hypercholesterolemic rats. J Shin YJ Kim MS Choi DH Woo T Park, Biofactors 2004 22 173 175 10.1002/biof.5520220135 15630277 (Pubitemid 40921784)
25. Role of oxidative stress in atherosclerosis. D Harrison KK Griendling U Landmesser B Hornig H Drexler, Am J Cardiol 2003 91 7A 11A 10.1016/S0002- 9149(02)03144-2 12645638 (Pubitemid 36351457)
26. Oxidative stress and vascular disease. NR Madamanchi A Vendrov MS Runge, Arterioscler Thromb Vasc Biol 2005 25 29 38 15539615 (Pubitemid 40054251)
27. Oxidative stress and atherosclerosis. U Singh I Jialal, Pathophysiology 2006 13 129 142 10.1016/j.pathophys.2006.05.002 16757157
28. Zinc, antioxidant systems and metallothionein in metal mediated-apoptosis: biochemical and cytochemical aspects. A Formigari P Irato A Santon, Comp Biochem Physiol C Toxicol Pharmacol 2007 146 443 459 10.1016/j.cbpc.2007.07.010 17716951 (Pubitemid 47494685)
29. Metabolism and functions of glutathione in brain. R Dringen, Prog Neurobiol 2000 62 649 671 10.1016/S0301-0082(99)00060-X 10880854 (Pubitemid 30407139)
30. Micronutrient-Enriched Rapeseed Oils Improve the Brain Oxidant/Antioxidant System in Rats Fed a High-Fat Diet. S Salvati L Attorri R Di Benedetto S Fortuna A Di Biase, J Agric Food Chem 2011 59 4483 4488 10.1021/jf1042807 21417278
31. Effects of dietary cold-pressed turnip rapeseed oil and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome. A Palomaki H Pohjantahti-Maaroos M Wallenius P Kankkunen H Aro S Husgafvel JM Pihlava K Oksanen, Lipids Health Dis 2010 9 137 10.1186/1476-511X-9-137 21122147
32. Phytosterols in human nutrition. RE Ostlund Jr, Annu Rev Nutr 2002 22 533 549 10.1146/annurev.nutr.22.020702.075220 12055357 (Pubitemid 35221472)
33. Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women. J Plat RP Mensink, FASEB J 2002 16 258 260 11772951
34. Effect of micronutrient-enriched sunflower oils on plasma lipid profile and antioxidant status in high-fat-fed rats. R Di Benedetto L Attorri F Chiarotti A Eusepi A Di Biase S Salvati, J Agric Food Chem 2010 58 5328 5333 10.1021/jf904360y 20356081
35. Inflammation in atherosclerosis. P Libby, Nature 2002 420 868 874 10.1038/nature01323 12490960 (Pubitemid 36019640)
36. Inflammation as a cardiovascular risk factor. JT Willerson PM Ridker, Circulation 2004 109 I2 10 15173056
37. Inflammation in atherosclerosis: from pathophysiology to practice. P Libby PM Ridker GK Hansson, J Am Coll Cardiol 2009 54 2129 2138 10.1016/j.jacc.2009.09.009 19942084
38. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. PM Ridker N Rifai L Rose JE Buring NR Cook, N Engl J Med 2002 347 1557 1565 10.1056/NEJMoa021993 12432042 (Pubitemid 35315836)
39. C-reactive protein, interleukin-6, and soluble adhesion molecules as predictors of progressive peripheral atherosclerosis in the general population: Edinburgh Artery Study. I Tzoulaki GD Murray AJ Lee A Rumley GD Lowe FG Fowkes, Circulation 2005 112 976 983 10.1161/CIRCULATIONAHA.104.513085 16087797 (Pubitemid 41170265)
40. Circulating markers of inflammation are related to carotid artery atherosclerosis. PT Larsson S Hallerstam S Rosfors NH Wallen, Int Angiol 2005 24 43 51 15876998 (Pubitemid 43933048)
41. Flavonoids protect LDL from oxidation and attenuate atherosclerosis. B Fuhrman M Aviram, Curr Opin Lipidol 2001 12 41 48 10.1097/00041433-200102000- 00008 11176202 (Pubitemid 32121284)
42. Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction. WM Loke JM Proudfoot JM Hodgson AJ McKinley N Hime M Magat R Stocker KD Croft, Arterioscler Thromb Vasc Biol 2010 30 749 757 10.1161/ATVBAHA.109.199687 20093625
43. Effects of dietary vitamin E on the biosynthesis of 5-lipoxygenase products by rat polymorphonuclear leukocytes (PMNL). AC Chan K Tran DD Pyke WS Powell, Biochim Biophys Acta 1989 1005 265 269 2508746 (Pubitemid 19241553)
44. beta-Sitosterol down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in J774A.1 murine macrophages. M Valerio AB Awad, Int Immunopharmacol