메뉴 건너뛰기




Volumn 11, Issue 5, 2011, Pages 560-571

Targeting aldose reductase for the treatment of cancer

Author keywords

Aldose reductase; Cancer and NF B; Inflammation; Oxidative stress

Indexed keywords

ACETIC ACID DERIVATIVE; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CHEMOKINE; CIGARETTE SMOKE; CISPLATIN; CYCLOOXYGENASE 2; CYTOKINE; DIESEL FUEL; EPALRESTAT; FIDARESTAT; GALACTITOL; GLUCOSE; GROWTH FACTOR; IDITOL DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PONALRESTAT; RANIRESTAT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUCCINIMIDE; SUGAR PHOSPHATE; TOLRESTAT; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; ZENARESTAT; ZOPOLRESTAT;

EID: 79958120421     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/156800911795655958     Document Type: Review
Times cited : (71)

References (113)
  • 1
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham, D.; Alexandre, J.; Huang, P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug. Discov. 2009, 8, 579-591.
    • (2009) Nat. Rev. Drug. Discov. , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 2
    • 64149096611 scopus 로고    scopus 로고
    • Anti-oxidants for therapeutic use: Why are only a few drugs in clinical use?
    • Suzuki, K. Anti-oxidants for therapeutic use: why are only a few drugs in clinical use? Adv. Drug Deliv. Rev. 2009, 61, 287-289.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 287-289
    • Suzuki, K.1
  • 3
    • 64249117887 scopus 로고    scopus 로고
    • Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering
    • Chan, E. C.; Jiang, F.; Peshavariya, H. M.; Dusting, G. J. Regulation of cell proliferation by NADPH oxidase-mediated signaling: potential roles in tissue repair, regenerative medicine and tissue engineering. Pharmacol. Ther. 2009, 122, 97-108.
    • (2009) Pharmacol. Ther , vol.122 , pp. 97-108
    • Chan, E.C.1    Jiang, F.2    Peshavariya, H.M.3    Dusting, G.J.4
  • 4
    • 43449100667 scopus 로고    scopus 로고
    • Reactive oxygen species: Current knowledge and applications in cancer research and therapeutic
    • Lau, A. T.; Wang, Y.; Chiu, J. F. Reactive oxygen species: current knowledge and applications in cancer research and therapeutic. J. Cell Biochem. 2008, 104, 657-667.
    • (2008) J. Cell Biochem , vol.104 , pp. 657-667
    • Lau, A.T.1    Wang, Y.2    Chiu, J.F.3
  • 5
    • 34548508693 scopus 로고    scopus 로고
    • Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: A review of published adduct types and levels in humans
    • Nair, U.; Bartsch, H.; Nair, J. Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: a review of published adduct types and levels in humans. Free Radic. Biol. Med. 2007, 43, 1109-1120.
    • (2007) Free Radic. Biol. Med , vol.43 , pp. 1109-1120
    • Nair, U.1    Bartsch, H.2    Nair, J.3
  • 6
    • 37849013375 scopus 로고    scopus 로고
    • Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
    • Negre-Salvayre, A.; Coatrieux, C.; Ingueneau, C.; Salvayre, R. Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. Br. J. Pharmacol. 2008, 153, 6-20.
    • (2008) Br. J. Pharmacol , vol.153 , pp. 6-20
    • Negre-Salvayre, A.1    Coatrieux, C.2    Ingueneau, C.3    Salvayre, R.4
  • 7
    • 9644294192 scopus 로고    scopus 로고
    • Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis
    • Bartsch, H.; Nair, J. Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis. Cancer Detect. Prev. 2004, 28, 385-391.
    • (2004) Cancer Detect. Prev , vol.28 , pp. 385-391
    • Bartsch, H.1    Nair, J.2
  • 8
    • 2442536008 scopus 로고    scopus 로고
    • Expression of nonphagocytic NADPH oxidase system in the ocular lens
    • Rao, P. V.; Maddala, R.; John, F.; Zigler, J. S. Jr. Expression of nonphagocytic NADPH oxidase system in the ocular lens. Mol. Vis. 2004, 10, 112-121.
    • (2004) Mol. Vis , vol.10 , pp. 112-121
    • Rao, P.V.1    Maddala, R.2    John, F.3    Zigler Jr., J.S.4
  • 9
    • 4544250814 scopus 로고    scopus 로고
    • Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer ells
    • Vaquero, E. C.; Edderkaoui, M.; Pandol, S. J.; Gukovsky, I.; Gukovskaya, A. S. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer ells. J. Biol. Chem. 2004, 279, 34643-34654.
    • (2004) J. Biol. Chem , vol.279 , pp. 34643-34654
    • Vaquero, E.C.1    Edderkaoui, M.2    Pandol, S.J.3    Gukovsky, I.4    Gukovskaya, A.S.5
  • 10
    • 0034816327 scopus 로고    scopus 로고
    • Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells
    • Tacchini, L.; Dansi, P.; Matteucci, E.; Desiderio, M. A. Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells. Carcinogenesis 2001, 22, 1363-1371.
    • (2001) Carcinogenesis , vol.22 , pp. 1363-1371
    • Tacchini, L.1    Dansi, P.2    Matteucci, E.3    Desiderio, M.A.4
  • 11
    • 0034937842 scopus 로고    scopus 로고
    • Immunological aspects of alzheimer's disease: Therapeutic implications
    • Hoozemans, J. J.; Rozemuller, A. J.; Veerhuis, R.; Eikelenboom, P. Immunological aspects of alzheimer's disease: therapeutic implications. BioDrugs 2001, 15, 325-337.
    • (2001) BioDrugs , vol.15 , pp. 325-337
    • Hoozemans, J.J.1    Rozemuller, A.J.2    Veerhuis, R.3    Eikelenboom, P.4
  • 12
    • 0343674543 scopus 로고    scopus 로고
    • Protective and destructive immune reactions in apical periodontitis
    • Márton, I.; J.; Kiss, C. Protective and destructive immune reactions in apical periodontitis. Oral Microbiol. Immunol. 2000, 15, 139-150.
    • (2000) Oral Microbiol. Immunol , vol.15 , pp. 139-150
    • Márton, I.J.1    Kiss, C.2
  • 13
    • 71449114145 scopus 로고    scopus 로고
    • Inflammation, aging, and cancer: Tumoricidal versus tumorigenesis of immunity: A common denominator mapping chronic diseases
    • Khatami, M. Inflammation, aging, and cancer: tumoricidal versus tumorigenesis of immunity: a common denominator mapping chronic diseases. Cell Biochem. Biophys. 2009, 55, 55-79.
    • (2009) Cell Biochem. Biophys , vol.55 , pp. 55-79
    • Khatami, M.1
  • 14
    • 39649107358 scopus 로고    scopus 로고
    • Inflammation and the aging process: Devil or angel. Nutr
    • Gauldie, J. Inflammation and the aging process: devil or angel. Nutr. Rev. 2007, 65, S167-S169.
    • (2007) Rev. , vol.65
    • Gauldie, J.1
  • 17
    • 70349908064 scopus 로고    scopus 로고
    • Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-kappaB and AP-1
    • Sutcliffe, A. M.; Clarke, D. L.; Bradbury, D. A.; Corbett, L. M.; Patel, J. A.; Knox, A. J. Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-kappaB and AP-1. Br. J. Pharmacol. 2009, 157, 436-450.
    • (2009) Br. J. Pharmacol , vol.157 , pp. 436-450
    • Sutcliffe, A.M.1    Clarke, D.L.2    Bradbury, D.A.3    Corbett, L.M.4    Patel, J.A.5    Knox, A.J.6
  • 18
    • 77955537622 scopus 로고    scopus 로고
    • Mechanisms of tumor promotion by reactive oxygen species
    • Kobliakov, V. A. Mechanisms of tumor promotion by reactive oxygen species. Biochemistry (Mosc). 2010, 75, 675-685.
    • (2010) Biochemistry (Mosc). , vol.75 , pp. 675-685
    • Kobliakov, V.A.1
  • 19
    • 43749098070 scopus 로고    scopus 로고
    • NF-kappaB and cancer-identifying targets and mechanisms
    • Naugler, W. E.; Karin, M. NF-kappaB and cancer-identifying targets and mechanisms. Curr. Opin. Genet. Dev. 2008, 18, 19-26.
    • (2008) Curr. Opin. Genet. Dev , vol.18 , pp. 19-26
    • Naugler, W.E.1    Karin, M.2
  • 22
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • Gupta, G. P.; Massague, J. Cancer metastasis: building a framework, Cell 2006, 127, 79-95.
    • (2006) Cell , vol.127 , pp. 79-95
    • Gupta, G.P.1    Massague, J.2
  • 23
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
    • Karin, M.; Lawrence, T.; Nizet, V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 2006, 124, 823-835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 24
    • 33745892100 scopus 로고    scopus 로고
    • Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): Role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth
    • Ramana, K. V.; Bhatnagar, A.; Srivastava, S.; Yadav, U. C.; Awasthi, S.; Awasthi, Y. C.; Srivastava, S. K. Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth. J. Biol. Chem. 2006, 281, 17652-17660.
    • (2006) J. Biol. Chem. , vol.281 , pp. 17652-17660
    • Ramana, K.V.1    Bhatnagar, A.2    Srivastava, S.3    Yadav, U.C.4    Awasthi, S.5    Awasthi, Y.C.6    Srivastava, S.K.7
  • 25
    • 33750286521 scopus 로고    scopus 로고
    • Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells
    • Tammali, R.; Ramana, K. V.; Singhal, S. S.; Awasthi, S.; Srivastava, S. K. Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells. Cancer Res. 2006, 66, 9705-9713.
    • (2006) Cancer Res , vol.66 , pp. 9705-9713
    • Tammali, R.1    Ramana, K.V.2    Singhal, S.S.3    Awasthi, S.4    Srivastava, S.K.5
  • 26
    • 34249732513 scopus 로고    scopus 로고
    • Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells
    • Tammali, R.; Ramana, K. V.; Srivastava, S. K. Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252, 299-306.
    • (2007) Cancer Lett , vol.252 , pp. 299-306
    • Tammali, R.1    Ramana, K.V.2    Srivastava, S.K.3
  • 27
    • 18844369302 scopus 로고    scopus 로고
    • Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options
    • Srivastava, S. K.; Ramana, K. V.; Bhatnagar, A. Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Endocr. Rev. 2005, 26, 380-392.
    • (2005) Endocr. Rev. , vol.26 , pp. 380-392
    • Srivastava, S.K.1    Ramana, K.V.2    Bhatnagar, A.3
  • 28
    • 0000116568 scopus 로고
    • The mechanism of the transformation of glucose in fructose in the seminal vesicles
    • Hers, H. G. The mechanism of the transformation of glucose in fructose in the seminal vesicles. Biochim. Biophys. Acta 1956, 22, 202-203.
    • (1956) Biochim. Biophys. Acta , vol.22 , pp. 202-203
    • Hers, H.G.1
  • 29
    • 0000841548 scopus 로고
    • Formation of polyols by the lens of the rat with 'sugar' cataract
    • van Heyningen, R. Formation of polyols by the lens of the rat with 'sugar' cataract. Nature 1959, 468, 194-195.
    • (1959) Nature , vol.468 , pp. 194-195
    • van Heyningen, R.1
  • 30
    • 0017337516 scopus 로고
    • Diabetic cataracts and flavonoids
    • Varma, S. D.; Mizuno, A.; Kinoshita, J. H. Diabetic cataracts and flavonoids. Science 1977, 195, 205-206.
    • (1977) Science , vol.195 , pp. 205-206
    • Varma, S.D.1    Mizuno, A.2    Kinoshita, J.H.3
  • 31
    • 0019502698 scopus 로고
    • Aldose reductase in diabetic cataracts
    • Kinoshita, J. H.; Kador, P.; Catiles, M. Aldose reductase in diabetic cataracts. JAMA 1981, 246, 257-261.
    • (1981) JAMA , vol.246 , pp. 257-261
    • Kinoshita, J.H.1    Kador, P.2    Catiles, M.3
  • 32
    • 0020282928 scopus 로고
    • Susceptibility of aldehyde and aldose reductases of human tissues to aldose reductase inhibitors
    • Srivastava, S. K.; Petrash, J. M.; Sadana, I. J.; Ansari, N. H.; Partridge, C. A. Susceptibility of aldehyde and aldose reductases of human tissues to aldose reductase inhibitors. Curr. Eye Res. 1982, 2, 407-410.
    • (1982) Curr. Eye Res. , vol.2 , pp. 407-410
    • Srivastava, S.K.1    Petrash, J.M.2    Sadana, I.J.3    Ansari, N.H.4    Partridge, C.A.5
  • 33
    • 0023806489 scopus 로고
    • Prevention of sugar-induced cataractogenesis in rats by butylated hydroxytoluene
    • Srivastava, S. K.; Ansari, N. H. Prevention of sugar-induced cataractogenesis in rats by butylated hydroxytoluene. Diabetes 1988, 37, 1505-1508.
    • (1988) Diabetes , vol.37 , pp. 1505-1508
    • Srivastava, S.K.1    Ansari, N.H.2
  • 35
    • 0028346373 scopus 로고
    • A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase
    • Donohue, P. J.; Alberts, G. F.; Hampton, B. S.; Winkles, J. A. A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase. J. Biol. Chem. 1994, 269, 8604-8609.
    • (1994) J. Biol. Chem , vol.269 , pp. 8604-8609
    • Donohue, P.J.1    Alberts, G.F.2    Hampton, B.S.3    Winkles, J.A.4
  • 36
    • 0026689111 scopus 로고
    • Aldose reductase mRNA expression and its activity are induced by glucose in fetal rat aortic smooth muscle (A10) cells
    • Tawata, M.; Ohtaka, M.; Hosaka, Y.; Onaya, T. Aldose reductase mRNA expression and its activity are induced by glucose in fetal rat aortic smooth muscle (A10) cells. Life Sci. 1992, 51, 719-726.
    • (1992) Life Sci. , vol.51 , pp. 719-726
    • Tawata, M.1    Ohtaka, M.2    Hosaka, Y.3    Onaya, T.4
  • 37
    • 0000572813 scopus 로고    scopus 로고
    • Nitric oxide upregulates aldose reductase expression in rat vascular smooth muscle cells: A potential role for aldose reductase in vascular remodeling
    • Seo, H. G.; Nishinaka, T.; Yabe-Nishimura, C. Nitric oxide upregulates aldose reductase expression in rat vascular smooth muscle cells: a potential role for aldose reductase in vascular remodeling. Mol. Pharmacol. 2000, 57, 709-717.
    • (2000) Mol. Pharmacol , vol.57 , pp. 709-717
    • Seo, H.G.1    Nishinaka, T.2    Yabe-Nishimura, C.3
  • 38
    • 0037199974 scopus 로고    scopus 로고
    • Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells
    • Ramana, K. V.; Chandra, D.; Srivastava, S.; Bhatnagar, A.; Aggarwal, B. B.; Srivastava, S. K. Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells. J. Biol. Chem. 2002, 277, 32063-32070. http://edrv.endojournals.org/cgi/ijlink?linkType=ABST&journalCode=jbc&resid=277/35/32063.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32063-32070
    • Ramana, K.V.1    Chandra, D.2    Srivastava, S.3    Bhatnagar, A.4    Aggarwal, B.B.5    Srivastava, S.K.6
  • 40
    • 33845962827 scopus 로고    scopus 로고
    • Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages
    • Ramana, K, V.; Fadl, A. A.; Tammali, R.; Reddy, A. B.; Chopra, A. K.; Srivastava, S. K. Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages. J. Biol. Chem. 2006, 281, 33019-33029.
    • (2006) J. Biol. Chem , vol.281 , pp. 33019-33029
    • Ramana, K.V.1    Fadl, A.A.2    Tammali, R.3    Reddy, A.B.4    Chopra, A.K.5    Srivastava, S.K.6
  • 41
    • 33947250147 scopus 로고    scopus 로고
    • Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages
    • Ramana, K. V.; Reddy, A. B.; Tammali, R.; Srivastava, S. K. Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages. Free Radic. Biol. Med. 2007, 42, 1290-1302.
    • (2007) Free Radic. Biol. Med , vol.42 , pp. 1290-1302
    • Ramana, K.V.1    Reddy, A.B.2    Tammali, R.3    Srivastava, S.K.4
  • 42
    • 65549117476 scopus 로고    scopus 로고
    • Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation
    • Tammali, R.; Reddy, A. B.; Ramana, K. V.; Petrash, J. M.; Srivastava, S. K. Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation. Carcinogenesis 2009, 30, 799-807.
    • (2009) Carcinogenesis , vol.30 , pp. 799-807
    • Tammali, R.1    Reddy, A.B.2    Ramana, K.V.3    Petrash, J.M.4    Srivastava, S.K.5
  • 44
    • 70350778508 scopus 로고    scopus 로고
    • Aldo-Keto reductase family 1 member B1 inhibitors: Old drugs with new perspectives
    • Jianghua, L.; Gebo, W.; Deliang, C. Aldo-Keto reductase family 1 member B1 inhibitors: Old drugs with new perspectives. Recent Pat. Anti-Canc. 2009, 4, 246-253.
    • (2009) Recent Pat. Anti-Canc. , vol.4 , pp. 246-253
    • Jianghua, L.1    Gebo, W.2    Deliang, C.3
  • 45
    • 77956227831 scopus 로고    scopus 로고
    • Aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy: A review
    • Schemmel K. E.; Rosalyn, S.; Padiyara, R. S.; D'Souza, J. J. Aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy: a review. J. Diabetes Complications 2010, 24, 354-360.
    • (2010) J. Diabetes Complications , vol.24 , pp. 354-360
    • Schemmel, K.E.1    Rosalyn, S.2    Padiyara, R.S.3    D'Souza, J.J.4
  • 46
    • 33644663628 scopus 로고    scopus 로고
    • Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis and glial reactivation in the retina of db/db mice
    • Cheung, A. K.; Fung, M. K.; Lo, A. C. Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis and glial reactivation in the retina of db/db mice. Diabetes 2005, 54, 3119-3125.
    • (2005) Diabetes , vol.54 , pp. 3119-3125
    • Cheung, A.K.1    Fung, M.K.2    Lo, A.C.3
  • 47
    • 0028838996 scopus 로고
    • Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA
    • Yamaoka, T.; Nishimura, C.; Yamashita, K. Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA. Diabetologia 1995, 38, 255-261.
    • (1995) Diabetologia , vol.38 , pp. 255-261
    • Yamaoka, T.1    Nishimura, C.2    Yamashita, K.3
  • 48
    • 0035486938 scopus 로고    scopus 로고
    • Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy
    • Hotta, N.; Toyota, T.; Matsuoka, K. Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy. Diabetes Care 2001, 24, 1776-1782.
    • (2001) Diabetes Care , vol.24 , pp. 1776-1782
    • Hotta, N.1    Toyota, T.2    Matsuoka, K.3
  • 49
    • 8644251442 scopus 로고    scopus 로고
    • Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860)
    • Asano, T.; Saito, Y.; Kawakami, M. Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860). J. Diabetes Complicat. 2004, 18, 336-342.
    • (2004) J. Diabetes Complicat. , vol.18 , pp. 336-342
    • Asano, T.1    Saito, Y.2    Kawakami, M.3
  • 52
    • 0028335907 scopus 로고
    • Identification of tumor-associated protein variants during rat hepatocarcinogenesis. Aldose reductase
    • Zeindl-Eberhart, E.; Jungblut, P. R.; Otto, A.; Rabes, H. M. Identification of tumor-associated protein variants during rat hepatocarcinogenesis. Aldose reductase. J. Biol. Chem. 1994, 269, 14589-14594.
    • (1994) J. Biol. Chem , vol.269 , pp. 14589-14594
    • Zeindl-Eberhart, E.1    Jungblut, P.R.2    Otto, A.3    Rabes, H.M.4
  • 56
    • 0025129179 scopus 로고
    • Purification and properties of aldose reductase and aldehyde reductase from EHS tumor cells
    • Tanimoto, T.; Sato, S.; Kador, P. F. Purification and properties of aldose reductase and aldehyde reductase from EHS tumor cells. Biochem. Pharmacol. 1990, 39, 445-453.
    • (1990) Biochem. Pharmacol , vol.39 , pp. 445-453
    • Tanimoto, T.1    Sato, S.2    Kador, P.F.3
  • 57
    • 33847299414 scopus 로고    scopus 로고
    • Association of cooking oil fumes exposure with lung cancer: Involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro
    • Hung, H. S.; Wu, W. J.; Cheng, Y. W.; Wu, T. C.;. Chang, K. L.; Lee, H. Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro. Mutat. Res. 2007, 628, 107-716.
    • (2007) Mutat. Res , vol.628 , pp. 107-716
    • Hung, H.S.1    Wu, W.J.2    Cheng, Y.W.3    Wu, T.C.4    Chang, K.L.5    Lee, H.6
  • 58
    • 0030796956 scopus 로고    scopus 로고
    • Relationships between cell density, glutathione and proliferation of A549 human lung adenocarcinoma cells treated with acrolein
    • Horton, N. D.; Mamiya, B. M.; Kehrer, J. P. Relationships between cell density, glutathione and proliferation of A549 human lung adenocarcinoma cells treated with acrolein. Toxicology 1997, 122, 111-122.
    • (1997) Toxicology , vol.122 , pp. 111-122
    • Horton, N.D.1    Mamiya, B.M.2    Kehrer, J.P.3
  • 59
    • 46049093970 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells
    • Yu, H.; Pan, C.; Zhao, S.; Wang, Z.; Zhang, H.; Wu, W. Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells. Biomed. Pharmacother. 2008, 62, 366-372.
    • (2008) Biomed. Pharmacother. , vol.62 , pp. 366-372
    • Yu, H.1    Pan, C.2    Zhao, S.3    Wang, Z.4    Zhang, H.5    Wu, W.6
  • 60
    • 34249913180 scopus 로고    scopus 로고
    • Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1
    • Huang, C. S.; Fan, Y. E.; Lin, C. Y.; Hu, M. L. Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1. J. Nutr. Biochem. 2007, 18, 449-456.
    • (2007) J. Nutr. Biochem. , vol.18 , pp. 449-456
    • Huang, C.S.1    Fan, Y.E.2    Lin, C.Y.3    Hu, M.L.4
  • 63
    • 42149160644 scopus 로고    scopus 로고
    • Expression of Nrf2 and its downstream gene targets in hibernating 13-lined ground squirrels, Spermophilus tridecemlineatus
    • Morin, P. Jr.; Ni, Z.; McMullen, D. C.; Storey, K. B. Expression of Nrf2 and its downstream gene targets in hibernating 13-lined ground squirrels, Spermophilus tridecemlineatus. Mol. Cell Biochem. 2008, 312, 121-129.
    • (2008) Mol. Cell Biochem , vol.312 , pp. 121-129
    • Morin Jr., P.1    Ni, Z.2    McMullen, D.C.3    Storey, K.B.4
  • 66
    • 43649105393 scopus 로고    scopus 로고
    • Cinnamaldehyde inhibits the tumor necrosis factoralpha-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-kappaB activation: Effects upon IkappaB and Nrf2
    • Liao, B. C.; Hsieh, C. W.; Liu, Y. C.; Tzeng, T. T.; Sun, Y. W.; Wung, B. S. Cinnamaldehyde inhibits the tumor necrosis factoralpha-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-kappaB activation: effects upon IkappaB and Nrf2. Toxicol. Appl. Pharmacol. 2008, 229, 161-171.
    • (2008) Toxicol. Appl. Pharmacol , vol.229 , pp. 161-171
    • Liao, B.C.1    Hsieh, C.W.2    Liu, Y.C.3    Tzeng, T.T.4    Sun, Y.W.5    Wung, B.S.6
  • 68
    • 14644397287 scopus 로고    scopus 로고
    • Transcription factor Nrf2 regulates promoter activity of mouse aldose reductase (AKR1B3) gene
    • Nishinaka, T.; Yabe-Nishimura, C. Transcription factor Nrf2 regulates promoter activity of mouse aldose reductase (AKR1B3) gene. J. Pharmacol. Sci. 2005, 97, 43-51.
    • (2005) J. Pharmacol. Sci. , vol.97 , pp. 43-51
    • Nishinaka, T.1    Yabe-Nishimura, C.2
  • 70
    • 31544467532 scopus 로고    scopus 로고
    • Nutritional epigenetics: Impact of folate deficiency on DNA methylation and colon cancer susceptibility
    • Kim, Y. Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility. J. Nutr. 2005, 135, 2703-2709.
    • (2005) J. Nutr. , vol.135 , pp. 2703-2709
    • Kim, Y.1
  • 71
    • 0026072467 scopus 로고
    • Nonmutagenic mechanisms in carcinogenesis: Role of protein kinase C in signal transduction and growth control
    • Weinstein, I. B. Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control. Environ. Health Perspect. 1991, 93, 175-179.
    • (1991) Environ. Health Perspect. , vol.93 , pp. 175-179
    • Weinstein, I.B.1
  • 72
    • 79958084268 scopus 로고    scopus 로고
    • Diagnosis and management of dysplasia and cancer of the ileal pouch in patients with underlying inflammatory bowel disease
    • doi: 10.1002/cncr.25886
    • Liu, Z. X.; Kiran, R. P.; Bennett, A. E.; Ni, R. Z; Shen, B. Diagnosis and management of dysplasia and cancer of the ileal pouch in patients with underlying inflammatory bowel disease. Cancer 2011 doi: 10.1002/cncr.25886.
    • (2011) Cancer
    • Liu, Z.X.1    Kiran, R.P.2    Bennett, A.E.3    Ni, R.Z.4    Shen, B.5
  • 73
    • 0034676333 scopus 로고    scopus 로고
    • 2 synthesis in Caco-2 human colon carcinoma cells
    • 2 synthesis in Caco-2 human colon carcinoma cells. Oncogene 2000, 19, 5517-1524.
    • (2000) Oncogene , vol.19 , pp. 5517-1524
    • Di Popolo, A.1    Memoli, A.2    Apicella, A.3
  • 74
    • 16544373045 scopus 로고    scopus 로고
    • Platelet-derived growth factor-induced arachidonic acid release for enhancement of prostaglandin E(2) synthesis in human gingival fibroblasts pretreated with interleukin-1ß
    • Nakao, S.; Ogata, Y.; Yamamoto, Y.; Furuyama, S.; Sugiya, H. Platelet-derived growth factor-induced arachidonic acid release for enhancement of prostaglandin E(2) synthesis in human gingival fibroblasts pretreated with interleukin-1ß. J. Cell Biochem. 2004, 92, 579-590.
    • (2004) J. Cell Biochem. , vol.92 , pp. 579-590
    • Nakao, S.1    Ogata, Y.2    Yamamoto, Y.3    Furuyama, S.4    Sugiya, H.5
  • 76
    • 0141816863 scopus 로고    scopus 로고
    • Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53
    • Swamy, M. V.; Herzog, C. R.; Rao, C. V. Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53. Cancer Res. 2003, 63, 5239-5242.
    • (2003) Cancer Res , vol.63 , pp. 5239-5242
    • Swamy, M.V.1    Herzog, C.R.2    Rao, C.V.3
  • 77
    • 74049140048 scopus 로고    scopus 로고
    • Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways
    • Schetter, A. J.; Heegaard, N. H.; Harris, C. C. Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 2010, 31, 37-49.
    • (2010) Carcinogenesis , vol.31 , pp. 37-49
    • Schetter, A.J.1    Heegaard, N.H.2    Harris, C.C.3
  • 78
    • 77950460778 scopus 로고    scopus 로고
    • The role of infection in the aetiology of inflammatory bowel disease
    • Hansen, R.; Thomson, J. M.; El-Omar, E. M.; Hold, G. L. The role of infection in the aetiology of inflammatory bowel disease. J. Gastroenterol. 2010, 45, 266-276.
    • (2010) J. Gastroenterol , vol.45 , pp. 266-276
    • Hansen, R.1    Thomson, J.M.2    El-Omar, E.M.3    Hold, G.L.4
  • 79
    • 13944249144 scopus 로고    scopus 로고
    • Regulation in S phase by E2F
    • Pardee, A.B.; Li, C.J.; Reddy, G.P. Regulation in S phase by E2F. Cell Cycle 2004, 3, 1091-2004.
    • (2004) Cell Cycle , vol.3 , pp. 1091-2004
    • Pardee, A.B.1    Li, C.J.2    Reddy, G.P.3
  • 80
    • 77950830294 scopus 로고    scopus 로고
    • Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells
    • Ramana, K. V.; Tammali, R.; Srivastava, S. K. Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells. Mol. Cancer Ther. 2010, 9, 813-824.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 813-824
    • Ramana, K.V.1    Tammali, R.2    Srivastava, S.K.3
  • 82
    • 0021713491 scopus 로고
    • Aldose metabolism in developing human fetal brain and liver
    • Samanta, B. K.; Chandra, N. C.; Ghosh, S.; Mukherjee, K. L. Aldose metabolism in developing human fetal brain and liver. Experientia 1984, 40, 1420-1422.
    • (1984) Experientia , vol.40 , pp. 1420-1422
    • Samanta, B.K.1    Chandra, N.C.2    Ghosh, S.3    Mukherjee, K.L.4
  • 83
    • 0031925073 scopus 로고    scopus 로고
    • New member of aldose reductase family proteins overexpressed in human hepatocellular carcinoma
    • Scuric, Z.; Stain, S. C.; Anderson, W. F.; Hwang, J. J. New member of aldose reductase family proteins overexpressed in human hepatocellular carcinoma. Hepatology 1998, 27, 943-950.
    • (1998) Hepatology , vol.27 , pp. 943-950
    • Scuric, Z.1    Stain, S.C.2    Anderson, W.F.3    Hwang, J.J.4
  • 84
    • 0029963946 scopus 로고    scopus 로고
    • Induction of aldose reductase gene expression in LEC rats during the development of the hereditary hepatitis and hepatoma
    • Takahashi, M.; Hoshi, A.; Fujii, J.; Miyoshi, E.; Kasahara, T.; Suzuki, K.; Aozasa, K.; Taniguchi, N. Induction of aldose reductase gene expression in LEC rats during the development of the hereditary hepatitis and hepatoma. Jpn. J. Cancer Res. 1996, 87, 337-341.
    • (1996) Jpn. J. Cancer Res , vol.87 , pp. 337-341
    • Takahashi, M.1    Hoshi, A.2    Fujii, J.3    Miyoshi, E.4    Kasahara, T.5    Suzuki, K.6    Aozasa, K.7    Taniguchi, N.8
  • 85
    • 0029127117 scopus 로고
    • Elevation of aldose reductase gene expression in rat primary hepatoma and hepatoma cell lines: Implication in detoxification of cytotoxic aldehydes
    • Takahashi, M.; Fujii, J.; Miyoshi, E.; Hoshi, A.; Taniguchi, N. Elevation of aldose reductase gene expression in rat primary hepatoma and hepatoma cell lines: implication in detoxification of cytotoxic aldehydes. Int. J. Cancer 1995, 62, 749-754.
    • (1995) Int. J. Cancer , vol.62 , pp. 749-754
    • Takahashi, M.1    Fujii, J.2    Miyoshi, E.3    Hoshi, A.4    Taniguchi, N.5
  • 86
    • 63449132720 scopus 로고    scopus 로고
    • Diallyl sulfide protects against Nnitrosodiethylamine-induced liver tumorigenesis: Role of aldose reductase
    • Ibrahim, S. S.; Nassar, N. N. Diallyl sulfide protects against Nnitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase. World J. Gastroenterol. 2008, 40, 6145-6153.
    • (2008) World J. Gastroenterol , vol.40 , pp. 6145-6153
    • Ibrahim, S.S.1    Nassar, N.N.2
  • 87
    • 26244453775 scopus 로고    scopus 로고
    • Review article: Anorexia and cachexia in gastrointestinal cancer
    • Ockenga, J.; Valentini, L. Review article: anorexia and cachexia in gastrointestinal cancer. Aliment Pharmacol. Ther. 2005, 22, 583-594.
    • (2005) Aliment Pharmacol. Ther , vol.22 , pp. 583-594
    • Ockenga, J.1    Valentini, L.2
  • 89
    • 79958143686 scopus 로고    scopus 로고
    • Tisdale. Cancer cachexia
    • Michael, J.; Tisdale. Cancer cachexia. Langenbecks Arch. Surg. 2004, 389, 299-305.
    • (2004) Langenbecks Arch. Surg. , vol.389 , pp. 299-305
    • Michael, J.1
  • 90
    • 0030880483 scopus 로고    scopus 로고
    • Induction of muscle protein degradation by a tumour factor
    • Lorite, M. J.; Cariuk, P.; Tisdale, M. J. Induction of muscle protein degradation by a tumour factor. Br. J. Cancer 1997, 76, 1035-1040.
    • (1997) Br. J. Cancer , vol.76 , pp. 1035-1040
    • Lorite, M.J.1    Cariuk, P.2    Tisdale, M.J.3
  • 91
    • 0033696398 scopus 로고    scopus 로고
    • NF-kB mediates the protein loss induced by TNF-a in differentiated skeletal muscle myotubes
    • Li, Y. P.; Reid, M. B. NF-kB mediates the protein loss induced by TNF-a in differentiated skeletal muscle myotubes. Am. J. Physiol. 2000, 279, R1165-R1170.
    • (2000) Am. J. Physiol , vol.279
    • Li, Y.P.1    Reid, M.B.2
  • 92
    • 0027956188 scopus 로고
    • Characterization of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes
    • Berg, M.; Fraker, D. L.; Alexander, H. R. Characterization of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes. Cytokine 1994, 6, 425-432.
    • (1994) Cytokine , vol.6 , pp. 425-432
    • Berg, M.1    Fraker, D.L.2    Alexander, H.R.3
  • 93
    • 10544222015 scopus 로고    scopus 로고
    • Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinomabearing mice with modulation of lysosomal and ATPubiquitindependent proteolytic pathways
    • Fujita, J.; Tsujinaka, T.; Yano, M. Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinomabearing mice with modulation of lysosomal and ATPubiquitindependent proteolytic pathways. Int. J. Cancer 1996, 68, 637-643.
    • (1996) Int. J. Cancer , vol.68 , pp. 637-643
    • Fujita, J.1    Tsujinaka, T.2    Yano, M.3
  • 94
    • 0035293048 scopus 로고    scopus 로고
    • Proteolysis-inducing factor regulates hepatic gene expression via the transcription factors NF-kB and STAT3
    • Watchorn, T. M.; Waddell, I. D.; Dowidar, N.; Ross, J. A. Proteolysis-inducing factor regulates hepatic gene expression via the transcription factors NF-kB and STAT3. FASEB J. 2001, 15, 562-564.
    • (2001) FASEB J. , vol.15 , pp. 562-564
    • Watchorn, T.M.1    Waddell, I.D.2    Dowidar, N.3    Ross, J.A.4
  • 95
    • 9144264926 scopus 로고    scopus 로고
    • Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NFkappaB activation
    • Wyke, S. M.; Russell, S. T.; Tisdale, M. J. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NFkappaB activation. Br. J. Cancer 2004, 91, 1742-1750.
    • (2004) Br. J. Cancer , vol.91 , pp. 1742-1750
    • Wyke, S.M.1    Russell, S.T.2    Tisdale, M.J.3
  • 97
    • 0032806466 scopus 로고    scopus 로고
    • Ponalrestat, an aldose reductase inhibitor, inhibits cachexia syndrome in nude mice bearing human melanomas G361 and SEKI
    • Kawamura, I.; Lacey, E.; Inami, M.; Nishigaki, F.; Naoe, Y.; Tsujimoto, S.; Manda, T.; Goto, T. Ponalrestat, an aldose reductase inhibitor, inhibits cachexia syndrome in nude mice bearing human melanomas G361 and SEKI. Anticancer Res. 1999, 19, 4091-4097.
    • (1999) Anticancer Res , vol.19 , pp. 4091-4097
    • Kawamura, I.1    Lacey, E.2    Inami, M.3    Nishigaki, F.4    Naoe, Y.5    Tsujimoto, S.6    Manda, T.7    Goto, T.8
  • 99
    • 73949102380 scopus 로고    scopus 로고
    • Multidrug resistance in cancer
    • Baguley, B. C. Multidrug resistance in cancer. Methods Mol. Biol. 2010, 596, 1-14.
    • (2010) Methods Mol. Biol , vol.596 , pp. 1-14
    • Baguley, B.C.1
  • 100
    • 73449126570 scopus 로고    scopus 로고
    • Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review
    • Liu, F. S. Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review. Taiwan J. Obstet. Gynecol. 2009, 48, 239-244.
    • (2009) Taiwan J. Obstet. Gynecol , vol.48 , pp. 239-244
    • Liu, F.S.1
  • 102
    • 62549108159 scopus 로고    scopus 로고
    • ABC transporters, drug resistance, and cancer stem cells
    • Dean, M. ABC transporters, drug resistance, and cancer stem cells. J. Mammary Gland Biol. Neoplasia 2009, 14, 3-9.
    • (2009) J. Mammary Gland Biol. Neoplasia , vol.14 , pp. 3-9
    • Dean, M.1
  • 103
    • 60749091249 scopus 로고    scopus 로고
    • Targeted cancer therapeutics
    • Hait, W. N.; Hambley, T. W. Targeted cancer therapeutics. Cancer Res. 2009, 69, 1263-1267.
    • (2009) Cancer Res. , vol.69 , pp. 1263-1267
    • Hait, W.N.1    Hambley, T.W.2
  • 106
    • 41249097311 scopus 로고    scopus 로고
    • Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers
    • Verma, M.; Martin, H. J.; Haq, W.; O'Connor, T. R.; Maser, E.; Balendiran, G. K. Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. Eur. J. Pharmacol. 2008, 584, 213-221.
    • (2008) Eur. J. Pharmacol , vol.584 , pp. 213-221
    • Verma, M.1    Martin, H.J.2    Haq, W.3    O'Connor, T.R.4    Maser, E.5    Balendiran, G.K.6
  • 110
    • 0036746965 scopus 로고    scopus 로고
    • Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases
    • Lee, E. K.; Regenold, W. T.; Shapiro, P. Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. Anticancer Drugs 2002, 13, 859-868.
    • (2002) Anticancer Drugs , vol.13 , pp. 859-868
    • Lee, E.K.1    Regenold, W.T.2    Shapiro, P.3
  • 111
    • 0035097039 scopus 로고    scopus 로고
    • Overexpression of aldose reductase in liver cancers may contribute to drug resistance
    • Lee, K. W.; Ko, B. C.; Jiang, Z.; Cao, D.; Chung, S. S. Overexpression of aldose reductase in liver cancers may contribute to drug resistance. Anticancer Drugs 2001, 12, 129-132.
    • (2001) Anticancer Drugs , vol.12 , pp. 129-132
    • Lee, K.W.1    Ko, B.C.2    Jiang, Z.3    Cao, D.4    Chung, S.S.5
  • 112
    • 70749089191 scopus 로고    scopus 로고
    • Aldose reductase: A novel therapeutic target for inflammatory pathologies
    • Ramana, K. V.; Srivastava, S. K. Aldose reductase: a novel therapeutic target for inflammatory pathologies. Int. J. Biochem. Cell Biol. 2010, 42, 17-20.
    • (2010) Int. J. Biochem. Cell Biol , vol.42 , pp. 17-20
    • Ramana, K.V.1    Srivastava, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.