Adverse effects of 2,4-dichlorophenoxyacetic acid on rat cerebellar granule cell cultures were attenuated by amphetamine

Neurotoxicity Research

Volumn 19, Issue 4, 2011, Pages 544-555

  Bongiovanni, B ^a   Ferri, A ^a   Brusco, A ^b   Rassetto, M ^a   Lopez, L M ^b   Evangelista De Duffard, A M ^a   Duffard, R ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

2,4 D; Amphetamine; Apoptosis; Nerve cell culture; Oxidative stress; Protective effect

Indexed keywords

AMPHETAMINE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL PROTECTION; CELL STRUCTURE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GRANULE CELL; NERVE CELL CULTURE; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

2,4-DICHLOROPHENOXYACETIC ACID; AMPHETAMINE; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYTOPLASMIC GRANULES; FEMALE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PREGNANCY; PROTEIN BINDING; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 79958084874     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-010-9188-9     Document Type: Article

References (56)

1. Adkins DL, Jones TA (2005) D-Amphetamine enhances skilled reaching after ischemic cortical lesions in rats. Neurosci Lett 380:214-218 (Pubitemid 40616082)
2. Ahmed I, Fedoroff S (1992) Preparation of cultures for electron microscopy. In: Fedoroff S, Richardson A (eds) Protocols for neural cell culture. Humana Press, Totowa, NJ, pp 165-170
3. Beers RF, Sizer JW (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 195:133-140
4. Belizário JE, Alves J, Occhiucci JM, Garay-Malpartida M, Sesso A (2007) A mechanistic view of mitochondrial death decision pores. Braz J Med Biol Res 40:1011-1024 (Pubitemid 47232855)
5. Bongaerts PA (2008) What of apoptosis is important: the decay process or the causative origin? Med Hypotheses 70:482-487
6. Bongiovanni B, De Lorenzi P, Ferri A, Konjuh C, Rassetto M, Evangelista de Duffard AM, Cardinali DP, Duffard R (2007) Melatonin decreases the oxidative stress produced by 2,4-dichlorophenoxyacetic acid in rat cerebellar granule cells. Neurotox Res 11:93-99
7. Bortolozzi A, Evangelista de Duffard AM, Dajas F, Duffard R, Silveira R (2001) Intracerebral administration of 2,4-diclorophenoxyacetic acid induces behavioral and neurochemical alterations in the rat brain. Neurotoxicology 22:221-232 (Pubitemid 32499703)
8. Bradberry SM, Watt BE, Proudfoot AT, Vale JA (2000) Mechanisms of toxicity, clinical features, and management of acute chlorophenoxy herbicide poisoning: a review. J Clin Toxicol 38:111-122 (Pubitemid 30212832)
9. Brown JM, Yamamoto BK (2003) Effects of amphetamines on mitochondrial function: role of free radicals and oxidative stress. Pharmacol Ther 99:45-53 (Pubitemid 36694749)
10. Brusco A, Saavedra JP, Garcia G, Tagliaferro P, Evangelista de Duffard AM, Duffard R (1997) 2,4-Dichlorophenoxyacetic acid through lactation induces astrogliosis in rat brain. Mol Chem Neuropathol 30:175-185 (Pubitemid 27215419)
11. Bukowska B (2003) Effects of 2,4-D and its metabolite 2,4-dicholophenol on antioxidant enzymes and level of glutathione in human erytrocytes. Comp Biochem Physiol C Toxicol Pharmacol 135:435-441
12. Bukowska B, Chajdys A, Duda W, Duchnowicz P (2000) Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites. Cell Biol Int 24:705-711
13. Carmody RJ, Cotter TG (2001) Signalling apoptosis: a radical approach. Redox Rep 6:77-90 (Pubitemid 32519815)
14. Carrì MT, Ferri A, Cozzolino M, Calabrese L, Rotilio G (2003) Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Review Brain Res Bull 61:365-374 (Pubitemid 36945467)
15. De Moliner KL, Evangelista de Duffard AM, Soto E, Duffard R, Adamo AM (2002) Induction of apoptosis in cerebellar granule cells by 2,4-dichlorophenoxyacetic acid. Neurochem Res 27:1439-1446 (Pubitemid 36014155)
16. Di Paolo O, de Duffard AM, Duffard R (2001) In vivo and in vitro binding of 2,4-dichlorophenoxyacetic acid to a rat liver mitochondrial protein. Chem Biol Interact 137:229-241
17. Dringer R (2000) Metabolism and funcions of glutathione in brain. Prog Neurobiol 62:649-671
18. Emerit J, Edeas M, Bricaire F (2004) Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58:39-46 (Pubitemid 38117047)
19. Feeney DM, Sutton RL (1988) Catecholamines and recovery of function after brain damage. In: Sabel BA, Stein D (eds) Pharmacological approaches to the treatment of Brain and spinal cord injury. Plenum Press, New York, pp 121-142
20. Ferri A, Duffard R, Stürtz N, Evangelista de Duffard AM (2003) Iron, zinc and copper levels in brain, serum and liver of neonates exposed to 2,4-dichlorophenoxyacetic acid. Neurotoxicol Teratol 25:607-613 (Pubitemid 37103059)
21. Ferri A, Duffard R, Evangelista de Duffard AM (2007) Selective oxidative stress in brain areas of neonate rats exposed to 2,4-dichlorophenoxyacetic acid through mother's milk. Drug Chem Toxicol 30:17-30
22. Frey BN, Valvassori SS, Gomes KM, Martins MR, Dal-Pizzol F, Kapczinski F, Quevedo J (2006) Increased oxidative stress in submitochondrial particle. Brain Res 1097:224-229
23. Gallo V, Suiergiu R, Giovannini C, Levi G (1987) Glutamate receptor subtypes in culture cerebellar neurons: modulation of glutamate and gamma-aminobutyric acid release. J Neurochem 49:1801-1809 (Pubitemid 17164638)
24. Garabrant DH, Philbert MA (2002) Review of 2,4-dichlorophenoxyacetic acid (2,4-D) epidemiology and toxicology. Crit Rev Toxicol 32:233-257 (Pubitemid 34856500)
25. Goldstein LB (2000) Effects of amphetamines and small related molecules on recovery after stroke in animals and man. Neuropharmacology 39:852-859
26. Halliwell B (1992) Reactive oxygen species and the central nervous system. J Neurochem 59:1609-1623
27. Horrocks DL (1974) Mode of standardization. In: Horrocks DL (ed) Applications of liquid scintillation counting. Academic Press, New York, pp 72-74
28. Johnson DL, Lardy H (1967) Isolation of rat liver mitochondria. In: Estabrook RW, Pullman ME (eds) Methods in enzymology, vol 10. Academic Press, Orlando, FL, pp 94-95
29. Kaioumova D, Kaioumov F, Opelz G, Süsal C (2001a) Toxic effects of the herbicide 2,4-dichlorophenoxyacetic acid on lymphoid organs of the rat. Chemosphere 43:801-805 (Pubitemid 32409344)
30. Kaioumova D, Süsal C, Opelz G (2001b) Induction of apoptosis in human lymphocytes by the herbicide 2,4-dichlorophenoxyacetic acid. Hum Immunol 62:64-74 (Pubitemid 32163935)
31. Leist M, Single B, Castoldi AF, Kuhnle S, Nicotera P (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med 185:1481-1486 (Pubitemid 27187604)
32. Martinsson L, Eksborg S (2004) Drugs for stroke recovery: the example of amphetamines. Drugs Aging 21:67-79 (Pubitemid 38293787)
33. McCord EF, Fridovich I (1969) Superoxide dismutase. An enzimic function for erythocuprein (hemocuprein). J Biol Chem 244:6049-6055
34. Michiels C, Raes M, Toussaint O, Remacle J (2002) Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic Biol Med 17:235-248
35. Miranda KM, Espey MG, Wink DA (2001) A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 5:62-71 (Pubitemid 34146173)
36. Moroz IA, Peciña S, Schallert T, Stewart J (2004) Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regime of amphetamine. Exp Neurol 189:78-93 (Pubitemid 39024457)
37. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
38. Mueller D, Chapman CA, Stewart J (2006) Amphetamine induces dendritic growth in Ventral Tegmental area dopaminergic neurons in vivo via basic fibroblast growth factor. Neuroscience 137:727-735 (Pubitemid 43053938)
39. Myhre O, Vestad TA, Sagstuen E, Aarnes H, Fonnum F (2000) The effects of aliphatic (n-nonane), naphtenic (1,2-trimethylbenzene) hydrocarbons on respiratory burst in human neutronphil granulocytes. Toxicol Appl Pharmacol 167:222-230
40. Nicotera P, Leist M (1997) Mitochondrial signals and energy requirement in cell death. Cell Death Differ 4:516
41. Nieminen AL (2003) Apoptosis and necrosis in health and disease: role of mitochondria. Int Rev Cytol 224:29-55
42. Nieminen AL, Saylor AK, Tesfal SA, Herman B, Lemasters JJ (1995) Contribution of mitochondrial permeability transition to lethal injury after exposure of hepatocyte to tbutylhydroperoxide. Biochem J 307:99-106
43. Oakes DJ, Pollack JK (1999) Effects of a herbicide formulation, Tordon 75D, and its individual components on the oxidative functions of mitochondria. Toxicology 136:41-52
44. Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158-169
45. Park JS, Wang M, Park SJ, Lee SH (1999) Zinc finger of replication protein A, a non-DNA binding element, regulates its DNA binding activity through redox. J Biol Chem 274:29075-29080
46. Peterson GA (1977) A simplification of the protein assay of Lowry et al. which is more generally applicable. Anal Biochem 83:346-356
47. Qian T, Herman B, Lemasters J (1999) The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol Appl Pharmacol 154:117-125 (Pubitemid 29072493)
48. Reynolds ES (1963) The use of lead citrate at high pH as an electronopaque stain in electron microscopy. J Cell Biol 17:208-212
49. Riddle EL, Hanson GR, Fleckenstein AE (2007) Therapeutic doses of amphetamine and methylphenidate selectively redistribute the vesicular monoamine transporter-2. Eur J Pharmacol 571:25-28 (Pubitemid 47284046)
50. Rosso SB, Cáceres AO, Evangelista de Duffard AM, Duffard R, Quiroga S (2000) 2,4-Dichlorophenoxyacetic acid disrupts the cytoskeleton and disorganizes the Golgi apparatus of culture neurons. Toxicol Sci 56:133-140 (Pubitemid 30441472)
51. Sato N, Iwata S, Nakamura K, Hori T, Mori K, Yodoi J (1995) Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis. J Immunol 154:3194-3203
52. Thomas B, Muralikrishnan D, Mohanakumar KP (2000) In vivo hydroxyl radical generation in the striatum following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain Res 852:221-224
53. Tuschl H, Schwab S (2003) Cytotoxic effects of the herbicide 2,4-dichlorophenoxyacetic acid in HepG2 cells. Food Chem Toxicol 41:385-393 (Pubitemid 36015776)
54. Wüllner U, Seyfried J, Groscurth P, Beinroth S, Winter S, Gleichmann M, Heneka M, Löschmann P, Schulz JB, Weller M, Klockgether T (1999) Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function. Brain Res 826:53-62 (Pubitemid 29222959)
55. Yun HY, Dawson VL, Dawson TM (1996) Neurobiology of nitric oxide. Crit Rev Neurobiol 10:291-316 (Pubitemid 27036101)
56. Yutaka E, Shigeomi S, Yoshihide T (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57:1835-1840