Intracerebral administration of 2,4-diclorophenoxyacetic acid induces behavioral and neurochemical alterations in the rat brain

NeuroToxicology

Volumn 22, Issue 2, 2001, Pages 221-232

  Bortolozzi, Analı́a ^a   Evangelista de Duffard, Ana Marı́a ^a   Dajas, Federico ^b   Duffard, Ricardo ^a   Silveira, Rodolfo ^c  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE   (Uruguay)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

2,4 Dichlorophenoxyacetic acid; 6 Hydroxydopamine; Basal ganglia; Locomotor and circling behavior; Monoamines

Indexed keywords

2,4 DICHLOROPHENOXYACETIC ACID; APOMORPHINE; DOPAMINE RECEPTOR; OXIDOPAMINE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN; CIRCLING BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; FOREBRAIN; INJECTION; LOCOMOTION; MALE; MONOAMINERGIC SYSTEM; NEUROCHEMISTRY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; ROTATION; SUBSTANTIA NIGRA;

2,4-DICHLOROPHENOXYACETIC ACID; ANIMALS; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; BRAIN CHEMISTRY; HERBICIDES; MALE; MEDIAL FOREBRAIN BUNDLE; MOTOR ACTIVITY; NEOSTRIATUM; NUCLEUS ACCUMBENS; OXIDOPAMINE; RATS; RATS, WISTAR; STEREOTYPED BEHAVIOR;

ANIMALIA;

EID: 0034981042     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-813X(01)00014-6     Document Type: Article

References (47)

1. Functional architecture of basal ganglia circuits: Neural substrates of parallel processing
2. Phencyclidine and (+)-MK-801-induced circling preference: Correlation with monoamine levels in striatum of the rat brain
3. Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: Implications for behavioral recovery from brain injury
4. Pesticides industry sales and usage: 1994 and 1995 market estimates
5. Neuropathy following exposure to a dimethylamine salt of 2,4-D
6. Dopamine-containing systems in the CNS
7. Regionally specific changes in central brain monoamine levels by 2,4-dichlorophenoxyacetic acid in acute treated rats
8. Peripheral serotoninergic system alterations in rats exposed during different periods of their life to neurotoxic 2,4-dichlorophenoxyacetic acid
9. Behavioral alterations induced in rats by a pre- and post-natal exposure to 2,4-dichlorophenoxyacetic acid
10. Behavioral differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: Relevance to nuerological symptoms in clinical syndromes with reduced brain dopamine
11. Intracerebral injection of phospholipase A2 inhibits dopamine-mediated behavior in rats: Possible implications for schizophrenia
12. 2,4-Dichlorophenoxyacetic acid through lactation induces astrogliosis in rat brain
13. Vulnerability of the myelin development of the chicks to the herbicide 2,4-dichlorophenoxyacetic butyl ester
14. Central nervous system myelin deficit in rats exposed to 2,4-dichlorophenoxyacetic acid through lactation
15. Inhibition of human and rabbit platelet aggregation by chlorophenoxyacid herbicides
16. Behavioral changes in rats fed a diet containing 2,4-dichlorophenoxyacetic butyl ester
17. Changes in brain serotonin and 5-hydroxyindolacetic acid levels induced by 2,4-dichlorophenoxyacetic butyl ester
18. Altered behavioral responses in 2,4-dichlorophenoxyacetic acid treated and amphetamine challenged rats
19. Immunological changes among farmers exposed to phenoxy herbicides: Preliminary observations
20. Dopaminergic regulation of the serotonergic raphe-striatal pathway: Microdialysis studies in freely moving rats
21. Differentiation of motor inactivation from movement asymmetry effects in a animal model of hemi-parkinsonism
22. Nocturnal rotation in normal rats: Correlation with amphetamine-induced rotation and effects of nigrostriatal lesions
23. Neurochemical studies on central dopamine neurons. Regional characterization of dopamine turnover
24. Basal ganglia
25. Effect of the dopamine D-1 antagonist SCH 23390 on rotational behavior induced by apomorphine and pergolide in 6-hydroxydopamine denervated rats
26. Serotonin axon terminals in the ventral tegmental area of the rat: Fine structure and synaptic input to dopaminergic neurons
27. Striatal membrane-bound and soluble catechol-O-methyl-transferase after selective neuronal lesions in the rat
28. 2,4-Dichlorophenoxiacetic acid intoxication increases its accumulation within the barin
29. 2,4-Development of physiologically based pharmacokinetic model for dichorophenoxyacetic acid dosimetry in discrete areas of the rabbit brain
30. Mesocorticolimbic dopaminergic network: Functional and regulatory roles
31. Single-dose and chronic dietary neurotoxicity screening studies on 2,4-dichlorophenoxyacetic acid in rats
32. Impairments and compensatory adjustments in spontaneous movement after unilateral dopamine depletion in rats
33. Changes in the nigrostriatal projection associated with recovery from lesion-induced behavioral asymmetry
34. Behavioral analysis of asymmetries induced by unilateral 6-OHDA injections into the substantia nigra
35. Neurotoxicity of 2,4-dichlorophenoxyacetic butyl ester in chicks embryos
36. The rat brain
37. Effects of denervation and hyperinnervation on dopamine and serotonin systems in the rat neostriatum: Implications for human Parkinson's disease
38. Gonadectomy attenuates turning behavior produced by electrical stimulation of the nigrostriatal dopamine system in female but not male rats
39. Effects of 2,4-dichlorophenoxyacetic acid on central nervous system of developmental rats. Associated changes in ganglioside pattern
40. Effects of sex and laterality on the rotatory swimming behavior of normal mice
41. Behavioral and neurochemical dynamics of neurotoxic meso-striatal dopamine lesions
42. Pesticide use in the US and policy implications: A focus on herbicides
43. Asymmetrical orientation to edges of an open field: Modulation by striatal dopamine and relationship to motor asymmetries in the rat
44. Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigro-striatal dopamine system
45. Post-synaptic supersensitivity after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system
46. Estimation of the turnover of 3-methoxytyramine in the rat striatum by HPLC with electrochemical detection: Implications for the sequence in the cerebral metabolism of dopamine
47. Animals models of parkinsonism using selective neurotoxin: Clinical and basic implications