Cysteine 27 variant of the δ-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

Molecular and Cellular Biology

Volumn 31, Issue 11, 2011, Pages 2326-2340

  Sarajärvi, Timo ^a   Tuusa, Jussi T ^b   Haapasalo, Annakaisa ^a   Lackman, Jarkko J ^b   Sormunen, Raija ^b   Helisalmi, Seppo ^a   Roehr, Johannes T ^d   Parrado, Antonio R ^c   Mäkinen, Petra ^a   Bertram, Lars ^d   Soininen, Hilkka ^a   Tanzi, Rudolph E ^c   Petäjä Repo, Ulla E ^b   Hiltunen, Mikko ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; CYSTEINE; DELTA OPIATE RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; PROTEIN VARIANT; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; ENDOCYTOSIS; FLOW CYTOMETRY; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECEPTORS, OPIOID, DELTA; SIGNAL TRANSDUCTION;

EID: 79958060924     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05015-11     Document Type: Article

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