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Volumn 10, Issue 1, 2009, Pages 19-25

Assessment of Alzheimer's disease case-control associations using family-based methods

Author keywords

Alzheimer's disease; Family based association testing; Genetic association; Meta analysis; Risk factors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CELL SURFACE RECEPTOR; CYSTATIN C; DEATH ASSOCIATED PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE 1; DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 1BETA; LAMIN A; MITOCHONDRIAL PROTEIN; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN 13; NERVE PROTEIN; NICOTINIC RECEPTOR BETA2; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PRESENILIN 1; PRION PROTEIN; PROTEIN PCK1; PROTEIN SORCS1; PROTEIN SORL1; PROTEIN TFAM; PROTEIN TNK1; PROTEIN TYROSINE KINASE; TAU PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG;

EID: 58649121718     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10048-008-0151-3     Document Type: Article
Times cited : (62)

References (31)
  • 1
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • L Bertram MB McQueen K Mullin D Blacker RE Tanzi 2007 Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database Nat Genet 39 17 23
    • (2007) Nat Genet , vol.39 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5
  • 2
    • 0033654196 scopus 로고    scopus 로고
    • Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies
    • L Bertram D Blacker A Crystal K Mullin D Keeney J Jones 2000 Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies Exp Gerontol 35 1353 1361
    • (2000) Exp Gerontol , vol.35 , pp. 1353-1361
    • Bertram, L.1    Blacker, D.2    Crystal, A.3    Mullin, K.4    Keeney, D.5    Jones, J.6
  • 3
    • 33846613222 scopus 로고    scopus 로고
    • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
    • E Rogaeva Y Meng JH Lee Y Gu T Kawarai F Zou 2007 The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease Nat Genet 39 168 177
    • (2007) Nat Genet , vol.39 , pp. 168-177
    • Rogaeva, E.1    Meng, Y.2    Lee, J.H.3    Gu, Y.4    Kawarai, T.5    Zou, F.6
  • 4
    • 33646188852 scopus 로고    scopus 로고
    • Family-based designs in the age of large-scale gene-association studies
    • NM Laird C Lange 2006 Family-based designs in the age of large-scale gene-association studies Nat Rev Genet 7 385 394
    • (2006) Nat Rev Genet , vol.7 , pp. 385-394
    • Laird, N.M.1    Lange, C.2
  • 8
    • 0034054165 scopus 로고    scopus 로고
    • A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information
    • D Rabinowitz N Laird 2000 A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information Hum Hered 50 211 223
    • (2000) Hum Hered , vol.50 , pp. 211-223
    • Rabinowitz, D.1    Laird, N.2
  • 10
    • 0033561180 scopus 로고    scopus 로고
    • Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs
    • JS Witte WJ Gauderman DC Thomas 1999 Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs Am J Epidemiol 149 693 705
    • (1999) Am J Epidemiol , vol.149 , pp. 693-705
    • Witte, J.S.1    Gauderman, W.J.2    Thomas, D.C.3
  • 13
    • 34447559923 scopus 로고    scopus 로고
    • Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
    • A Grupe R Abraham Y Li C Rowland P Hollingworth A Morgan 2007 Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants Hum Mol Genet 16 865 873
    • (2007) Hum Mol Genet , vol.16 , pp. 865-873
    • Grupe, A.1    Abraham, R.2    Li, Y.3    Rowland, C.4    Hollingworth, P.5    Morgan, A.6
  • 14
    • 58649091124 scopus 로고    scopus 로고
    • Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta
    • doi: 10.1007/s10048-008-0150-4
    • Kauwe JS, Wang J, Mayo K, Morris JC, Fagan AM, Holtzman DM, Goate AM (2009) Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta. Neurogenetics. doi: 10.1007/s10048-008-0150-4
    • (2009) Neurogenetics
    • Kauwe, J.S.1    Wang, J.2    Mayo, K.3    Morris, J.C.4    Fagan, A.M.5    Holtzman, D.M.6    Goate, A.M.7
  • 15
    • 38449092192 scopus 로고    scopus 로고
    • The renin-angiotensin system, hypertension and cognitive dysfunction in Alzheimer's disease: New therapeutic potential
    • S Takeda N Sato T Ogihara R Morishita 2008 The renin-angiotensin system, hypertension and cognitive dysfunction in Alzheimer's disease: new therapeutic potential Front Biosci 13 2253 2265
    • (2008) Front Biosci , vol.13 , pp. 2253-2265
    • Takeda, S.1    Sato, N.2    Ogihara, T.3    Morishita, R.4
  • 18
    • 40149093247 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) levels and activity in Alzheimer's disease, and relationship of perivascular ACE-1 to cerebral amyloid angiopathy
    • JS Miners E Ashby Z Van Helmond KA Chalmers LE Palmer S Love 2008 Angiotensin-converting enzyme (ACE) levels and activity in Alzheimer's disease, and relationship of perivascular ACE-1 to cerebral amyloid angiopathy Neuropathol Appl Neurobiol 34 181 193
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 181-193
    • Miners, J.S.1    Ashby, E.2    Van Helmond, Z.3    Chalmers, K.A.4    Palmer, L.E.5    Love, S.6
  • 19
    • 0035930538 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); Retards A beta aggregation, deposition, fibril formation; And inhibits cytotoxicity
    • J Hu A Igarashi M Kamata H Nakagawa 2001 Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity J Biol Chem 276 47863 47868
    • (2001) J Biol Chem , vol.276 , pp. 47863-47868
    • Hu, J.1    Igarashi, A.2    Kamata, M.3    Nakagawa, H.4
  • 20
    • 33750047859 scopus 로고    scopus 로고
    • Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme
    • EA Eckman SK Adams FJ Troendle BA Stodola MA Kahn AH Fauq 2006 Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme J Biol Chem 281 30471 30478
    • (2006) J Biol Chem , vol.281 , pp. 30471-30478
    • Eckman, E.A.1    Adams, S.K.2    Troendle, F.J.3    Stodola, B.A.4    Kahn, M.A.5    Fauq, A.H.6
  • 21
    • 33947245344 scopus 로고    scopus 로고
    • Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease
    • ML Hemming DJ Selkoe W Farris 2007 Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease Neurobiol Dis 26 273 281
    • (2007) Neurobiol Dis , vol.26 , pp. 273-281
    • Hemming, M.L.1    Selkoe, D.J.2    Farris, W.3
  • 22
    • 33846782816 scopus 로고    scopus 로고
    • Iron and copper toxicity in diseases of aging, particularly atherosclerosis and Alzheimer's disease
    • GJ Brewer 2007 Iron and copper toxicity in diseases of aging, particularly atherosclerosis and Alzheimer's disease Exp Biol Med (Maywood) 232 323 335
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 323-335
    • Brewer, G.J.1
  • 24
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • MA Smith PL Harris LM Sayre G Perry 1997 Iron accumulation in Alzheimer disease is a source of redox-generated free radicals Proc Natl Acad Sci U S A 94 9866 9868
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 25
    • 0036724204 scopus 로고    scopus 로고
    • Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: Implications in the formation of neurofibrillary tangles of Alzheimer's disease
    • A Yamamoto RW Shin K Hasegawa H Naiki H Sato F Yoshimasu 2002 Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease J Neurochem 82 1137 1147
    • (2002) J Neurochem , vol.82 , pp. 1137-1147
    • Yamamoto, A.1    Shin, R.W.2    Hasegawa, K.3    Naiki, H.4    Sato, H.5    Yoshimasu, F.6
  • 26
    • 0033391822 scopus 로고    scopus 로고
    • The effect of transferrin polymorphisms on iron metabolism
    • PL Lee NJ Ho R Olson E Beutler 1999 The effect of transferrin polymorphisms on iron metabolism Blood Cells Mol Dis 25 374 379
    • (1999) Blood Cells Mol Dis , vol.25 , pp. 374-379
    • Lee, P.L.1    Ho, N.J.2    Olson, R.3    Beutler, E.4
  • 29
    • 33645026907 scopus 로고    scopus 로고
    • The role of nicotinic acetylcholine receptors in Alzheimer's disease
    • S Oddo FM LaFerla 2006 The role of nicotinic acetylcholine receptors in Alzheimer's disease J Physiol (Paris) 99 172 179
    • (2006) J Physiol (Paris) , vol.99 , pp. 172-179
    • Oddo, S.1    Laferla, F.M.2
  • 30
    • 0032502612 scopus 로고    scopus 로고
    • Age-related changes in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human frontal cortex and hippocampus
    • H Tohgi K Utsugisawa M Yoshimura Y Nagane M Mihara 1998 Age-related changes in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human frontal cortex and hippocampus Neurosci Lett 245 139 142
    • (1998) Neurosci Lett , vol.245 , pp. 139-142
    • Tohgi, H.1    Utsugisawa, K.2    Yoshimura, M.3    Nagane, Y.4    Mihara, M.5
  • 31
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein e genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
    • LA Farrer LA Cupples JL Haines B Hyman WA Kukull R Mayeux 1997 Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium JAMA 278 1349 1356
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3    Hyman, B.4    Kukull, W.A.5    Mayeux, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.