-
1
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
DOI 10.1038/363446a0
-
Hamers-Casterman, C., T. Atarhouch, S. Muyldermans, G. Robinson, C. Hamers, E. B. Songa, N. Bendahman, and R. Hamers. 1993. Naturally occurring antibodies devoid of light chains. Nature 363: 446-448. (Pubitemid 23179389)
-
(1993)
Nature
, vol.363
, Issue.6428
, pp. 446-448
-
-
Hamers-Casterman, C.1
Atarhouch, T.2
Muyldermans, S.3
Robinson, G.4
Hamers, C.5
Songa, E.B.6
Bendahman, N.7
Hamers, R.8
-
2
-
-
60849118639
-
Camelid immunoglobulins and nanobody technology
-
Muyldermans, S., T. N. Baral, V. C. Retamozzo, P. De Baetselier, E. De Genst, J. Kinne, H. Leonhardt, S. Magez, V. K. Nguyen, H. Revets, et al. 2009. Camelid immunoglobulins and nanobody technology. Vet. Immunol. Immunopathol. 128: 178-183.
-
(2009)
Vet. Immunol. Immunopathol.
, vol.128
, pp. 178-183
-
-
Muyldermans, S.1
Baral, T.N.2
Retamozzo, V.C.3
De Baetselier, P.4
De Genst, E.5
Kinne, J.6
Leonhardt, H.7
Magez, S.8
Nguyen, V.K.9
Revets, H.10
-
4
-
-
33845485045
-
Ablynx makes nanobodies from llama bodies
-
Wolfson, W. 2006. Ablynx makes nanobodies from llama bodies. Chem. Biol. 13: 1243-1244.
-
(2006)
Chem. Biol.
, vol.13
, pp. 1243-1244
-
-
Wolfson, W.1
-
5
-
-
59849107733
-
Outcome of a workshop on applications of protein models in biomedical research
-
Schwede, T., A. Sali, B. Honig, M. Levitt, H. M. Berman, D. Jones, S. E. Brenner, S. K. Burley, R. Das, N. V. Dokholyan, et al. 2009. Outcome of a workshop on applications of protein models in biomedical research. Structure 17: 151-159.
-
(2009)
Structure
, vol.17
, pp. 151-159
-
-
Schwede, T.1
Sali, A.2
Honig, B.3
Levitt, M.4
Berman, H.M.5
Jones, D.6
Brenner, S.E.7
Burley, S.K.8
Das, R.9
Dokholyan, N.V.10
-
6
-
-
79958047524
-
-
Available at: Accessed: April 12, 2011
-
Ablynx Corporate Overview. Available at: http://www.ablynx.com. Accessed: April 12, 2011.
-
Ablynx Corporate Overview
-
-
-
7
-
-
26044466715
-
Antibody repertoire development in camelids
-
De Genst, E., D. Saerens, S. Muyldermans, and K. Conrath. 2006. Antibody repertoire development in camelids. Dev. Comp. Immunol. 30: 187-198.
-
(2006)
Dev. Comp. Immunol.
, vol.30
, pp. 187-198
-
-
De Genst, E.1
Saerens, D.2
Muyldermans, S.3
Conrath, K.4
-
8
-
-
33748791745
-
Reliable and controllable antibody fragment selections from Camelid non-immune libraries for target validation
-
Verheesen, P., A. Roussis, H. J. de Haard, A. J. Groot, J. C. Stam, J. T. den Dunnen, R. R. Frants, A. J. Verkleij, C. Theo Verrips, and S. M. van der Maarel. 2006. Reliable and controllable antibody fragment selections from Camelid non-immune libraries for target validation. Biochim. Biophys. Acta 1764: 1307-1319.
-
(2006)
Biochim. Biophys. Acta
, vol.1764
, pp. 1307-1319
-
-
Verheesen, P.1
Roussis, A.2
De Haard, H.J.3
Groot, A.J.4
Stam, J.C.5
Den Dunnen, J.T.6
Frants, R.R.7
Verkleij, A.J.8
Verrips, C.T.9
Van Der Maarel, S.M.10
-
9
-
-
35348819390
-
Properties, production, and applications of camelid single-domain antibody fragments
-
Harmsen, M. M., and H. J. De Haard. 2007. Properties, production, and applications of camelid single-domain antibody fragments. Appl. Microbiol. Biotechnol. 77: 13-22.
-
(2007)
Appl. Microbiol. Biotechnol.
, vol.77
, pp. 13-22
-
-
Harmsen, M.M.1
De Haard, H.J.2
-
10
-
-
0028168145
-
Sequence and structure of V(H) domain from naturally occurring camel heavy chain immunoglobulins lacking light chains
-
Muyldermans, S., T. Atarhouch, J. Saldanha, J. A. Barbosa, and R. Hamers. 1994. Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains. Protein Eng. 7: 1129-1135. (Pubitemid 24282500)
-
(1994)
Protein Engineering
, vol.7
, Issue.9
, pp. 1129-1135
-
-
Muyldermans, S.1
Atarhouch, T.2
Saldanha, J.3
Barbosa, J.A.R.G.4
Hamers, R.5
-
11
-
-
0029746203
-
Single antibody domains as small recognition units: Design and in vitro antigen selection of camelized, human VH domains with improved protein stability
-
Davies, J., and L. Riechmann. 1996. Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability. Protein Eng. 9: 531-537. (Pubitemid 26261295)
-
(1996)
Protein Engineering
, vol.9
, Issue.6
, pp. 531-537
-
-
Davies, J.1
Riechmann, L.2
-
12
-
-
0035312546
-
Recognition of antigens by single-domain antibody fragments: The superfluous luxury of paired domains
-
Muyldermans, S., C. Cambillau, and L. Wyns. 2001. Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains. Trends Biochem. Sci. 26: 230-235.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 230-235
-
-
Muyldermans, S.1
Cambillau, C.2
Wyns, L.3
-
13
-
-
0033103453
-
Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies
-
Muyldermans, S., and M. Lauwereys. 1999. Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies. J. Mol. Recognit. 12: 131-140.
-
(1999)
J. Mol. Recognit.
, vol.12
, pp. 131-140
-
-
Muyldermans, S.1
Lauwereys, M.2
-
14
-
-
0033954256
-
The Protein Data Bank
-
Berman, H. M., J. Westbrook, Z. Feng, G. Gilliland, T. N. Bhat, H. Weissig, I. N. Shindyalov, and P. E. Bourne. 2000. The Protein Data Bank. Nucleic Acids Res. 28: 235-242.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
15
-
-
59449096415
-
Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking
-
Sivasubramanian, A., A. Sircar, S. Chaudhury, and J. J. Gray. 2009. Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking. Proteins 74: 497-514.
-
(2009)
Proteins
, vol.74
, pp. 497-514
-
-
Sivasubramanian, A.1
Sircar, A.2
Chaudhury, S.3
Gray, J.J.4
-
16
-
-
1842532008
-
A hierarchical approach to all-atom protein loop prediction
-
Jacobson, M. P., D. L. Pincus, C. S. Rapp, T. J. Day, B. Honig, D. E. Shaw, and R. A. Friesner. 2004. A hierarchical approach to all-atom protein loop prediction. Proteins 55: 351-367.
-
(2004)
Proteins
, vol.55
, pp. 351-367
-
-
Jacobson, M.P.1
Pincus, D.L.2
Rapp, C.S.3
Day, T.J.4
Honig, B.5
Shaw, D.E.6
Friesner, R.A.7
-
17
-
-
68349104348
-
Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling
-
Mandell, D. J., E. A. Coutsias, and T. Kortemme. 2009. Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling. Nat. Methods 6: 551-552.
-
(2009)
Nat. Methods
, vol.6
, pp. 551-552
-
-
Mandell, D.J.1
Coutsias, E.A.2
Kortemme, T.3
-
18
-
-
50549090182
-
PIGS: Automatic prediction of antibody structures
-
Marcatili, P., A. Rosi, and A. Tramontano. 2008. PIGS: automatic prediction of antibody structures. Bioinformatics 24: 1953-1954.
-
(2008)
Bioinformatics
, vol.24
, pp. 1953-1954
-
-
Marcatili, P.1
Rosi, A.2
Tramontano, A.3
-
19
-
-
48449094112
-
Conformer selection and induced fit in flexible backbone protein-protein docking using computational and NMR ensembles
-
Chaudhury, S., and J. J. Gray. 2008. Conformer selection and induced fit in flexible backbone protein-protein docking using computational and NMR ensembles. J. Mol. Biol. 381: 1068-1087.
-
(2008)
J. Mol. Biol.
, vol.381
, pp. 1068-1087
-
-
Chaudhury, S.1
Gray, J.J.2
-
20
-
-
76749153896
-
SnugDock: Paratope structural optimization during antibody-antigen docking compensates for errors in antibody homology models
-
Sircar, A., and J. J. Gray. 2010. SnugDock: paratope structural optimization during antibody-antigen docking compensates for errors in antibody homology models. PLOS Comput. Biol. 6: e1000644.
-
(2010)
PLOS Comput. Biol.
, vol.6
-
-
Sircar, A.1
Gray, J.J.2
-
21
-
-
0023989064
-
Improved tools for biological sequence comparison
-
Pearson, W. R., and D. J. Lipman. 1988. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85: 2444-2448.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 2444-2448
-
-
Pearson, W.R.1
Lipman, D.J.2
-
22
-
-
3042666256
-
MUSCLE: Multiple sequence alignment with high accuracy and high throughput
-
DOI 10.1093/nar/gkh340
-
Edgar, R. C. 2004. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32: 1792-1797. (Pubitemid 38832724)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.5
, pp. 1792-1797
-
-
Edgar, R.C.1
-
23
-
-
0030464460
-
SEAVIEW and PHYLO-WIN: Two graphic tools for sequence alignment and molecular phylogeny
-
Galtier, N., M. Gouy, and C. Gautier. 1996. SEAVIEW and PHYLO-WIN: two graphic tools for sequence alignment and molecular phylogeny. Comput. Appl. Biosci. 12: 543-548.
-
(1996)
Comput. Appl. Biosci.
, vol.12
, pp. 543-548
-
-
Galtier, N.1
Gouy, M.2
Gautier, C.3
-
25
-
-
0025183708
-
Basic local alignment search tool
-
Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215: 403-410.
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
26
-
-
0034641749
-
Native protein sequences are close to optimal for their structures
-
Kuhlman, B., and D. Baker. 2000. Native protein sequences are close to optimal for their structures. Proc. Natl. Acad. Sci. USA 97: 10383-10388.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10383-10388
-
-
Kuhlman, B.1
Baker, D.2
-
27
-
-
67849111558
-
RosettaAntibody: Antibody variable region homology modeling server
-
Sircar, A., E. T. Kim, and J. J. Gray. 2009. RosettaAntibody: antibody variable region homology modeling server. Nucleic Acids Res. 37(Web Server issue): W474-W479.
-
(2009)
Nucleic Acids Res.
, vol.37
, Issue.WEB SERVER ISSUE
-
-
Sircar, A.1
Kim, E.T.2
Gray, J.J.3
-
28
-
-
1642464839
-
Protein structure prediction using Rosetta
-
Rohl, C. A., C. E. Strauss, K. M. Misura, and D. Baker. 2004. Protein structure prediction using Rosetta. Methods Enzymol. 383: 66-93.
-
(2004)
Methods Enzymol.
, vol.383
, pp. 66-93
-
-
Rohl, C.A.1
Strauss, C.E.2
Misura, K.M.3
Baker, D.4
-
29
-
-
0037406075
-
Cyclic coordinate descent: A robotics algorithm for protein loop closure
-
Canutescu, A. A., and R. L. Dunbrack, Jr. 2003. Cyclic coordinate descent: a robotics algorithm for protein loop closure. Protein Sci. 12: 963-972.
-
(2003)
Protein Sci.
, vol.12
, pp. 963-972
-
-
Canutescu, A.A.1
Dunbrack Jr., R.L.2
-
30
-
-
17744364070
-
Improved side-chain modeling for protein-protein docking
-
Wang, C., O. Schueler-Furman, and D. Baker. 2005. Improved side-chain modeling for protein-protein docking. Protein Sci. 14: 1328-1339.
-
(2005)
Protein Sci.
, vol.14
, pp. 1328-1339
-
-
Wang, C.1
Schueler-Furman, O.2
Baker, D.3
-
31
-
-
0031585984
-
Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions
-
Simons, K. T., C. Kooperberg, E. Huang, and D. Baker. 1997. Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions. J. Mol. Biol. 268: 209-225.
-
(1997)
J. Mol. Biol.
, vol.268
, pp. 209-225
-
-
Simons, K.T.1
Kooperberg, C.2
Huang, E.3
Baker, D.4
-
32
-
-
0031558798
-
Standard conformations for the canonical structures of immunoglobulins
-
Al-Lazikani, B., A. M. Lesk, and C. Chothia. 1997. Standard conformations for the canonical structures of immunoglobulins. J. Mol. Biol. 273: 927-948.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 927-948
-
-
Al-Lazikani, B.1
Lesk, A.M.2
Chothia, C.3
-
33
-
-
34249777526
-
Eris: An automated estimator of protein stability
-
Yin, S., F. Ding, and N. V. Dokholyan. 2007. Eris: an automated estimator of protein stability. Nat. Methods 4: 466-467.
-
(2007)
Nat. Methods
, vol.4
, pp. 466-467
-
-
Yin, S.1
Ding, F.2
Dokholyan, N.V.3
-
34
-
-
0004032583
-
-
National Institutes of Health, Bethesda
-
Kabat, E. A., T. T. Wu, H. Bilofsky, M. Reid-Miller, and H. Perry. 1983. Sequence of Proteins of Immunological Interest. National Institutes of Health, Bethesda.
-
(1983)
Sequence of Proteins of Immunological Interest
-
-
Kabat, E.A.1
Wu, T.T.2
Bilofsky, H.3
Reid-Miller, M.4
Perry, H.5
-
35
-
-
48049124972
-
Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains
-
Abhinandan, K. R., and A. C. Martin. 2008. Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains. Mol. Immunol. 45: 3832-3839.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 3832-3839
-
-
Abhinandan, K.R.1
Martin, A.C.2
-
36
-
-
0026788298
-
Structural repertoire of the human VH segments
-
Chothia, C., A. M. Lesk, E. Gherardi, I. M. Tomlinson, G. Walter, J. D. Marks, M. B. Llewelyn, and G. Winter. 1992. Structural repertoire of the human VH segments. J. Mol. Biol. 227: 799-817.
-
(1992)
J. Mol. Biol.
, vol.227
, pp. 799-817
-
-
Chothia, C.1
Lesk, A.M.2
Gherardi, E.3
Tomlinson, I.M.4
Walter, G.5
Marks, J.D.6
Llewelyn, M.B.7
Winter, G.8
-
37
-
-
0027212854
-
Length distribution of CDRH3 in antibodies
-
Wu, T. T., G. Johnson, and E. A. Kabat. 1993. Length distribution of CDRH3 in antibodies. Proteins 16: 1-7.
-
(1993)
Proteins
, vol.16
, pp. 1-7
-
-
Wu, T.T.1
Johnson, G.2
Kabat, E.A.3
-
38
-
-
0030577371
-
Structural classification of CDRH3 in antibodies
-
Shirai, H., A. Kidera, and H. Nakamura. 1996. Structural classification of CDRH3 in antibodies. FEBS Lett. 399: 1-8.
-
(1996)
FEBS Lett.
, vol.399
, pp. 1-8
-
-
Shirai, H.1
Kidera, A.2
Nakamura, H.3
-
39
-
-
20444413418
-
Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH
-
Conrath, K., C. Vincke, B. Stijlemans, J. Schymkowitz, K. Decanniere, L. Wyns, S. Muyldermans, and R. Loris. 2005. Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. J. Mol. Biol. 350: 112-125.
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 112-125
-
-
Conrath, K.1
Vincke, C.2
Stijlemans, B.3
Schymkowitz, J.4
Decanniere, K.5
Wyns, L.6
Muyldermans, S.7
Loris, R.8
-
40
-
-
0035800596
-
Lateral recognition of a dye hapten by a llama VHH domain
-
Spinelli, S., M. Tegoni, L. Frenken, C. van Vliet, and C. Cambillau. 2001. Lateral recognition of a dye hapten by a llama VHH domain. J. Mol. Biol. 311: 123-129.
-
(2001)
J. Mol. Biol.
, vol.311
, pp. 123-129
-
-
Spinelli, S.1
Tegoni, M.2
Frenken, L.3
Van Vliet, C.4
Cambillau, C.5
-
41
-
-
17144383931
-
Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires
-
De Genst, E., K. Silence, M. A. Ghahroudi, K. Decanniere, R. Loris, J. Kinne, L. Wyns, and S. Muyldermans. 2005. Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J. Biol. Chem. 280: 14114-14121.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14114-14121
-
-
De Genst, E.1
Silence, K.2
Ghahroudi, M.A.3
Decanniere, K.4
Loris, R.5
Kinne, J.6
Wyns, L.7
Muyldermans, S.8
-
42
-
-
0034733379
-
Canonical antigen-binding loop structures in immunoglobulins: More structures, more canonical classes?
-
Decanniere, K., S. Muyldermans, and L. Wyns. 2000. Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes? J. Mol. Biol. 300: 83-91.
-
(2000)
J. Mol. Biol.
, vol.300
, pp. 83-91
-
-
Decanniere, K.1
Muyldermans, S.2
Wyns, L.3
-
43
-
-
0037189507
-
Three camelid VHH domains in complex with porcine pancreatic α-amylase. Inhibition and versatility of binding topology
-
Desmyter, A., S. Spinelli, F. Payan, M. Lauwereys, L. Wyns, S. Muyldermans, and C. Cambillau. 2002. Three camelid VHH domains in complex with porcine pancreatic α-amylase. Inhibition and versatility of binding topology. J. Biol. Chem. 277: 23645-23650.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23645-23650
-
-
Desmyter, A.1
Spinelli, S.2
Payan, F.3
Lauwereys, M.4
Wyns, L.5
Muyldermans, S.6
Cambillau, C.7
-
44
-
-
30044442097
-
Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses
-
Spinelli, S., A. Desmyter, C. T. Verrips, H. J. de Haard, S. Moineau, and C. Cambillau. 2006. Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses. Nat. Struct. Mol. Biol. 13: 85-89.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 85-89
-
-
Spinelli, S.1
Desmyter, A.2
Verrips, C.T.3
De Haard, H.J.4
Moineau, S.5
Cambillau, C.6
-
45
-
-
17144404243
-
A structure-based database of antibody variable domain diversity
-
Bond, C. J., C. Wiesmann, J. C. Marsters, Jr., and S. S. Sidhu. 2005. A structure-based database of antibody variable domain diversity. J. Mol. Biol. 348: 699-709.
-
(2005)
J. Mol. Biol.
, vol.348
, pp. 699-709
-
-
Bond, C.J.1
Wiesmann, C.2
Marsters Jr., J.C.3
Sidhu, S.S.4
-
46
-
-
0016374802
-
Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: Definitive identification of four heavy chain hypervariable regions
-
Capra, J. D., and J. M. Kehoe. 1974. Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions. Proc. Natl. Acad. Sci. USA 71: 845-848.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 845-848
-
-
Capra, J.D.1
Kehoe, J.M.2
-
47
-
-
0030993418
-
Antibody humanization using monovalent phage display
-
Baca, M., L. G. Presta, S. J. O'Connor, and J. A. Wells. 1997. Antibody humanization using monovalent phage display. J. Biol. Chem. 272: 10678-10684.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10678-10684
-
-
Baca, M.1
Presta, L.G.2
O'Connor, S.J.3
Wells, J.A.4
-
48
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
Carter, P., L. Presta, C. M. Gorman, J. B. Ridgway, D. Henner, W. L. Wong, A. M. Rowland, C. Kotts, M. E. Carver, and H. M. Shepard. 1992. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc. Natl. Acad. Sci. USA 89: 4285-4289.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4285-4289
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
Ridgway, J.B.4
Henner, D.5
Wong, W.L.6
Rowland, A.M.7
Kotts, C.8
Carver, M.E.9
Shepard, H.M.10
-
49
-
-
0034673109
-
Camelid heavy-chain variable domains provide efficient combining sites to haptens
-
DOI 10.1021/bi991830w
-
Spinelli, S., L. G. Frenken, P. Hermans, T. Verrips, K. Brown, M. Tegoni, and C. Cambillau. 2000. Camelid heavy-chain variable domains provide efficient combining sites to haptens. Biochemistry 39: 1217-1222. (Pubitemid 30090687)
-
(2000)
Biochemistry
, vol.39
, Issue.6
, pp. 1217-1222
-
-
Spinelli, S.1
Frenken, L.G.J.2
Hermans, P.3
Verrips, T.4
Brown, K.5
Tegoni, M.6
Cambillau, C.7
-
50
-
-
77951229808
-
FREAD revisited: Accurate loop structure prediction using a database search algorithm
-
Choi, Y., and C. M. Deane. 2010. FREAD revisited: accurate loop structure prediction using a database search algorithm. Proteins 78: 1431-1440.
-
(2010)
Proteins
, vol.78
, pp. 1431-1440
-
-
Choi, Y.1
Deane, C.M.2
-
51
-
-
24044472050
-
Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
-
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath. 2005. Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies. J. Mol. Biol. 352: 597-607.
-
(2005)
J. Mol. Biol.
, vol.352
, pp. 597-607
-
-
Saerens, D.1
Pellis, M.2
Loris, R.3
Pardon, E.4
Dumoulin, M.5
Matagne, A.6
Wyns, L.7
Muyldermans, S.8
Conrath, K.9
-
52
-
-
47349128896
-
Toward better refinement of comparative models: Predicting loops in inexact environments
-
Sellers, B. D., K. Zhu, S. Zhao, R. A. Friesner, and M. P. Jacobson. 2008. Toward better refinement of comparative models: predicting loops in inexact environments. Proteins 72: 959-971.
-
(2008)
Proteins
, vol.72
, pp. 959-971
-
-
Sellers, B.D.1
Zhu, K.2
Zhao, S.3
Friesner, R.A.4
Jacobson, M.P.5
-
53
-
-
77951215074
-
New computational method for prediction of interacting protein loop regions
-
Danielson, M. L., and M. A. Lill. 2010. New computational method for prediction of interacting protein loop regions. Proteins 78: 1748-1759.
-
(2010)
Proteins
, vol.78
, pp. 1748-1759
-
-
Danielson, M.L.1
Lill, M.A.2
-
54
-
-
0003187567
-
The atomic structure of protein-protein recognition sites
-
Lo Conte, L., C. Chothia, and J. Janin. 1999. The atomic structure of protein-protein recognition sites. J. Mol. Biol. 285: 2177-2198.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 2177-2198
-
-
Lo Conte, L.1
Chothia, C.2
Janin, J.3
-
55
-
-
0037322915
-
Hybrid Monte Carlo with multidimensional replica exchanges: Conformational equilibria of the hypervariable regions of a llama VHH antibody domain
-
Fenwick, M. K., and F. A. Escobedo. 2003. Hybrid Monte Carlo with multidimensional replica exchanges: conformational equilibria of the hypervariable regions of a llama VHH antibody domain. Biopolymers 68: 160-177.
-
(2003)
Biopolymers
, vol.68
, pp. 160-177
-
-
Fenwick, M.K.1
Escobedo, F.A.2
-
56
-
-
33645034410
-
Molecular mechanisms of pH-driven conformational transitions of proteins: Insights from continuum electrostatics calculations of acid unfolding
-
Fitch, C. A., S. T. Whitten, V. J. Hilser, and B. García-Moreno E. 2006. Molecular mechanisms of pH-driven conformational transitions of proteins: insights from continuum electrostatics calculations of acid unfolding. Proteins 63: 113-126.
-
(2006)
Proteins
, vol.63
, pp. 113-126
-
-
Fitch, C.A.1
Whitten, S.T.2
Hilser, V.J.3
García-Moreno E, B.4
-
57
-
-
67649700796
-
Engineered CH2 domains (nanoantibodies)
-
Dimitrov, D. S. 2009. Engineered CH2 domains (nanoantibodies). MAbs 1: 26-28.
-
(2009)
MAbs
, vol.1
, pp. 26-28
-
-
Dimitrov, D.S.1
-
58
-
-
77957966065
-
A generalized approach to sampling backbone conformations with RosettaDock for CAPRI rounds 13-19
-
Sircar, A., S. Chaudhury, K. P. Kilambi, M. Berrondo, and J. J. Gray. 2010. A generalized approach to sampling backbone conformations with RosettaDock for CAPRI rounds 13-19. Proteins 78: 3115-3123.
-
(2010)
Proteins
, vol.78
, pp. 3115-3123
-
-
Sircar, A.1
Chaudhury, S.2
Kilambi, K.P.3
Berrondo, M.4
Gray, J.J.5
-
59
-
-
17644422139
-
Use of human germline genes in a CDR homology-based approach to antibody humanization
-
DOI 10.1016/j.ymeth.2005.01.004, Humanized Antibodies and their Applications
-
Hwang, W. Y., J. C. Almagro, T. N. Buss, P. Tan, and J. Foote. 2005. Use of human germline genes in a CDR homology-based approach to antibody humanization. Methods 36: 35-42. (Pubitemid 40558814)
-
(2005)
Methods
, vol.36
, Issue.1
, pp. 35-42
-
-
Hwang, W.Y.K.1
Almagro, J.C.2
Buss, T.N.3
Tan, P.4
Foote, J.5
-
60
-
-
34548383489
-
Design of multi-specificity in protein interfaces
-
Humphris, E. L., and T. Kortemme. 2007. Design of multi-specificity in protein interfaces. PLOS Comput. Biol. 3: e164.
-
(2007)
PLOS Comput. Biol.
, vol.3
-
-
Humphris, E.L.1
Kortemme, T.2
-
61
-
-
69249158062
-
Computational design of affinity and specificity at protein-protein interfaces
-
Karanicolas, J., and B. Kuhlman. 2009. Computational design of affinity and specificity at protein-protein interfaces. Curr. Opin. Struct. Biol. 19: 458-463.
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 458-463
-
-
Karanicolas, J.1
Kuhlman, B.2
-
62
-
-
35148855712
-
Computational design of antibody-affinity improvement beyond in vivo maturation
-
Lippow, S. M., K. D. Wittrup, and B. Tidor. 2007. Computational design of antibody-affinity improvement beyond in vivo maturation. Nat. Biotechnol. 25: 1171-1176.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1171-1176
-
-
Lippow, S.M.1
Wittrup, K.D.2
Tidor, B.3
-
63
-
-
77958157337
-
OptCDR: A general computational method for the design of antibody complementarity determining regions for targeted epitope binding
-
Pantazes, R. J., and C. D. Maranas. 2010. OptCDR: a general computational method for the design of antibody complementarity determining regions for targeted epitope binding. Protein Eng. Des. Sel. 23: 849-858.
-
(2010)
Protein Eng. Des. Sel.
, vol.23
, pp. 849-858
-
-
Pantazes, R.J.1
Maranas, C.D.2
-
64
-
-
0035955552
-
Degenerate interfaces in antigen-antibody complexes
-
Decanniere, K., T. R. Transue, A. Desmyter, D. Maes, S. Muyldermans, and L. Wyns. 2001. Degenerate interfaces in antigen-antibody complexes. J. Mol. Biol. 313: 473-478.
-
(2001)
J. Mol. Biol.
, vol.313
, pp. 473-478
-
-
Decanniere, K.1
Transue, T.R.2
Desmyter, A.3
Maes, D.4
Muyldermans, S.5
Wyns, L.6
-
65
-
-
0033080945
-
Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing Fabs
-
DOI 10.1016/S0969-2126(99)80020-3
-
Stanfield, R., E. Cabezas, A. Satterthwait, E. Stura, A. Profy, and I. Wilson. 1999. Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure 7: 131-142. (Pubitemid 29159699)
-
(1999)
Structure
, vol.7
, Issue.2
, pp. 131-142
-
-
Stanfield, R.L.1
Cabezas, E.2
Satterthwait, A.C.3
Stura, E.A.4
Profy, A.T.5
Wilson, I.A.6
-
66
-
-
0033561250
-
A single-domain antibody fragment in complex with RNase A: Non-canonical loop structures and nanomolar affinity using two CDR loops
-
DOI 10.1016/S0969-2126(99)80049-5
-
Decanniere, K., A. Desmyter, M. Lauwereys, M. A. Ghahroudi, S. Muyldermans, and L. Wyns. 1999. A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops. Structure 7: 361-370. (Pubitemid 29190470)
-
(1999)
Structure
, vol.7
, Issue.4
, pp. 361-370
-
-
Decanniere, K.1
Desmyter, A.2
Lauwereys, M.3
Ghahroudi, M.A.4
Muyldermans, S.5
Wyns, L.6
|