A single-domain antibody fragment in complex with RNase A: Non-canonical loop structures and nanomolar affinity using two CDR loops

Structure

Volumn 7, Issue 4, 1999, Pages 361-370

  Decanniere, Klaas ^a   Desmyter, Aline ^a   Lauwereys, Marc ^a   Ghahroudi, Mehdi A ^b   Muyldermans, Serge ^a   Wyns, Lode ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

Canonical loop structures; Crystal structure; Hypervariable regions; Immunoglobulin

Indexed keywords

RIBONUCLEASE A;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR AFFINITY;

BOVINAE; CAMELIDAE; CAMELUS DROMEDARIUS;

EID: 0033561250     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(99)80049-5     Document Type: Article

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