Targeted overexpression of endothelin-1 in astrocytes leads to more severe cytotoxic brain edema and higher mortality

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 12, 2009, Pages 1891-1902

  Yeung, Patrick Ka Kit ^a   Lo, Amy Cheuk Yin ^a,b   Leung, Justin Wai Chung ^a   Chung, Stephen Sum Man ^a,b   Chung, Sookja Kim ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Aquaporin; Astrocyte; Cytotoxic edema; Endothelin 1; Vasopressin receptor antagonist; Water intoxication

Indexed keywords

AQUAPORIN 4; ENDOTHELIN 1; MOZAVAPTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN EDEMA; BRAIN INJURY; BRAIN TOXICITY; BRAIN WATER; CONTROLLED STUDY; CYTOTOXICITY; DISEASE EXACERBATION; DISEASE SEVERITY; GENE OVEREXPRESSION; HIPPOCAMPUS; MORTALITY; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SURVIVAL RATE; WATER CONTENT; WATER INTOXICATION;

ANIMALS; AQUAPORIN 4; ASTROCYTES; BENZAZEPINES; BRAIN; BRAIN EDEMA; ENDOTHELIN-1; GLIAL FIBRILLARY ACIDIC PROTEIN; MICE; MICE, TRANSGENIC; RECEPTORS, VASOPRESSIN; UP-REGULATION; WATER; WATER INTOXICATION;

EID: 72049122125     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.175     Document Type: Article

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