Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation

Blood

Volumn 117, Issue 22, 2011, Pages 5918-5930

  Quéré, Ronan ^a   Karlsson, Göran ^a   Hertwig, Falk ^a   Rissler, Marianne ^a   Lindqvist, Beata ^a   Fioretos, Thoas ^b   Vandenberghe, Peter ^c   Slovak, Marilyn L ^d   Cammenga, Jörg ^a   Karlsson, Stefan ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPORIN 98; SMAD4 PROTEIN; TRANSCRIPTION FACTOR HOXA9; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL IMMORTALIZATION; CELL NUCLEUS; CELL PROTECTION; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOPLASM; DRUG TARGETING; GROWTH REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

EID: 79957976682     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-08-301879     Document Type: Article

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