-
1
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nature Rev Cancer 2002; 2:38-47. (Pubitemid 37328806)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
27744536543
-
Targeting hypoxia and angiogenesis through HIF-1alpha inhibition
-
Diaz-Gonzalez JA, Russell J, Rouzaut A, Gil-Bazo I, Montuenga L. Targeting hypoxia and angiogenesis through HIF-1alpha inhibition. Cancer Biol Ther 2005; 4:1055-62. (Pubitemid 41598557)
-
(2005)
Cancer Biology and Therapy
, vol.4
, Issue.10
, pp. 1055-1062
-
-
Diaz-Gonzalez, J.A.1
Russell, J.2
Rouzaut, A.3
Gil-Bazo, I.4
Montuenga, L.5
-
3
-
-
77949273897
-
Hypoxiareoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2
-
Binker MG, Binker-Cosen AA, Richards D, Gaisano HY, de Cosen RH, Cosen-Binker LI. Hypoxiareoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2. Biochem Biophys Res Commun 2010; 393:371-6.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 371-376
-
-
Binker, M.G.1
Binker-Cosen, A.A.2
Richards, D.3
Gaisano, H.Y.4
De Cosen, R.H.5
Cosen-Binker, L.I.6
-
4
-
-
0033571682
-
Overexpression of hypoxiainducible factor1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, et al. Overexpression of hypoxiainducible factor1alpha in common human cancers and their metastases. Cancer Res 1999; 59:5830-5.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
-
5
-
-
0037617447
-
Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor
-
DOI 10.1038/sj.onc.1206373
-
Baba M, Hirai S, Yamada-Okabe H, Hamada K, Tabuchi H, Kobayashi K, et al. Loss of von Hippel- Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor. Oncogene 2003; 22:2728-38. (Pubitemid 36609588)
-
(2003)
Oncogene
, vol.22
, Issue.18
, pp. 2728-2738
-
-
Baba, M.1
Hirai, S.2
Yamada-Okabe, H.3
Hamada, K.4
Tabuchi, H.5
Kobayashi, K.6
Kondo, K.7
Yoshida, M.8
Yamashita, A.9
Kishida, T.10
Nakaigawa, N.11
Nagashima, Y.12
Kubota, Y.13
Yao, M.14
Ohno, S.15
-
6
-
-
0141956303
-
Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage
-
DOI 10.1038/sj.bjc.6601186
-
Kurokawa T, Miyamoto M, Kato K, Cho Y, Kawarada Y, Hida Y, et al. Overexpression of hypoxia-induciblefactor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Br J Cancer 2003; 89:1042-7. (Pubitemid 37239209)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.6
, pp. 1042-1047
-
-
Kurokawa, T.1
Miyamoto, M.2
Kato, K.3
Cho, Y.4
Kawarada, Y.5
Hida, Y.6
Shinohara, T.7
Itoh, T.8
Okushiba, S.9
Kondo, S.10
Katoh, H.11
-
7
-
-
13844276107
-
Correlation of hypoxia inducible factor-1alpha with lymphatic metastasis via vascular endothelial growth factor-C in human esophageal cancer
-
DOI 10.1016/j.yexmp.2004.11.002
-
Katsuta M, Miyashita M, Makino H, Nomura T, Shinji S, Yamashita K, et al. Correlation of hypoxia inducible factor-1 alpha with lymphatic metastasis via vascular endothelial growth factor-C in human esophageal cancer. Exp Mol Pathol 2005; 782:123-30. (Pubitemid 40248793)
-
(2005)
Experimental and Molecular Pathology
, vol.78
, Issue.2
, pp. 123-130
-
-
Katsuta, M.1
Miyashita, M.2
Makino, H.3
Nomura, T.4
Shinji, S.5
Yamashita, K.6
Tajiri, T.7
Kudo, M.8
Ishiwata, T.9
Naito, Z.10
-
8
-
-
3843107242
-
Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma
-
DOI 10.1016/j.ejca.2004.04.035, PII S095980490400406X
-
Kimura S, Kitadai Y, Tanaka S, Kuwai T, Hihara J, Yoshida K, et al. Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human esophageal squamous cell carcinoma. Eur J Cancer 2004; 40:1904-12. (Pubitemid 39036767)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.12
, pp. 1904-1912
-
-
Kimura, S.1
Kitadai, Y.2
Tanaka, S.3
Kuwai, T.4
Hihara, J.5
Yoshida, K.6
Toge, T.7
Chayama, K.8
-
9
-
-
0037414180
-
YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1
-
Yeo EJ, Chun YS, Cho YS, Kim J, Lee JC, Kim MS, et al. YC-1: a potential anticancer drug targeting hypoxiainducible factor 1. J Natl Cancer Inst 2003; 95:516-25. (Pubitemid 36511622)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.7
, pp. 516-525
-
-
Yeo, E.-J.1
Chun, Y.-S.2
Cho, Y.-S.3
Kim, J.4
Lee, J.-C.5
Kim, M.-S.6
Park, J.-W.7
-
10
-
-
33846990665
-
A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent
-
Kim HL, Yeo EJ, Chun YS, Park JW. A domain responsible for HIF-1alpha degradation by YC-1, a novel anticancer agent. Int J Oncol 2006; 29:255-60.
-
(2006)
Int J Oncol
, vol.29
, pp. 255-260
-
-
Kim, H.L.1
Yeo, E.J.2
Chun, Y.S.3
Park, J.W.4
-
11
-
-
0037131271
-
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha
-
DOI 10.1074/jbc.M206922200
-
Chan DA, Sutphin PD, Denko NC, Giaccia AJ. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. J Biol Chem 2002; 277:40112-7. (Pubitemid 35191002)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 40112-40117
-
-
Chan, D.A.1
Sutphin, P.D.2
Denko, N.C.3
Giaccia, A.J.4
-
12
-
-
22544464403
-
Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1alpha
-
DOI 10.1128/MCB.25.15.6415-6426.2005
-
Chan DA, Sutphin PD, Yen SE, Giaccia AJ. Coordinate regulation of the oxygendependent degradation domains of hypoxia-inducible factor a alpha. Mol Cell Biol 2005; 25:6415-26. (Pubitemid 41023218)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.15
, pp. 6415-6426
-
-
Chan, D.A.1
Sutphin, P.D.2
Yen, S.-E.3
Giaccia, A.J.4
-
13
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002; 8:62-7.
-
(2002)
Trends Mol Med
, vol.8
, pp. 62-67
-
-
Semenza, G.L.1
-
14
-
-
33745793405
-
Anti-apoptotic action by hypoxia inducible factor 1-alpha in human pituitary adenoma cell line, HP-75 in hypoxic condition
-
DOI 10.1007/s11060-005-9017-9
-
Yoshida D, Kim K, Noha M, Teramoto A. Antiapoptotic action by hypoxia inducible factor 1alpha in human pituitary adenoma cell line, HP-75 in hypoxic condition. J Neurooncol 2006; 78:217-25. (Pubitemid 44018814)
-
(2006)
Journal of Neuro-Oncology
, vol.78
, Issue.3
, pp. 217-225
-
-
Yoshida, D.1
Kim, K.2
Noha, M.3
Teramoto, A.4
-
15
-
-
33645005086
-
HIF-1alpha has an anti-apoptotic effect in human airway epithelium that is mediated via Mcl-1 gene expression
-
Liu XH, Yu EZ, Li YY, Kagan E. HIF-1alpha has an anti-apoptotic effect in human airway epithelium that is mediated via Mcl-1 gene expression. J Cell Biochem 2006; 97:755-65.
-
(2006)
J Cell Biochem
, vol.97
, pp. 755-765
-
-
Liu, X.H.1
Yu, E.Z.2
Li, Y.Y.3
Kagan, E.4
-
16
-
-
23844461100
-
Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo
-
DOI 10.1158/0008-5472.CAN-04-4426
-
Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik SW, et al. Evaluating hypoxia-inducible factor- 1alpha as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res 2005; 65:7249-58. (Pubitemid 41161256)
-
(2005)
Cancer Research
, vol.65
, Issue.16
, pp. 7249-7258
-
-
Li, L.1
Lin, X.2
Staver, M.3
Shoemaker, A.4
Semizarov, D.5
Fesik, S.W.6
Shen, Y.7
-
17
-
-
3843107242
-
Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma
-
DOI 10.1016/j.ejca.2004.04.035, PII S095980490400406X
-
Kimura S, Kitadai Y, Tanaka S, Kuwai T, Hihara J, Yoshida K, et al. Expression of hypoxia-inducible factor (HIF)-1 alpha is associated with vascular endothelial growth factor expression and tumor angiogenesis in human oesphageal squmaous cell carcinoma. Eur J Cancer 2004; 40:1904-12. (Pubitemid 39036767)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.12
, pp. 1904-1912
-
-
Kimura, S.1
Kitadai, Y.2
Tanaka, S.3
Kuwai, T.4
Hihara, J.5
Yoshida, K.6
Toge, T.7
Chayama, K.8
-
18
-
-
0036262188
-
Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases
-
Kondo S, Kubota S, Shimo T, Nakanishi T, Sasaki A, Mese H, et al. Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases. Carcinogenesis 2002; 23:769-76. (Pubitemid 34567515)
-
(2002)
Carcinogenesis
, vol.23
, Issue.5
, pp. 769-776
-
-
Kondo, S.1
Kubota, S.2
Shimo, T.3
Nishida, T.4
Yosimichi, G.5
Eguchi, T.6
Sugahara, T.7
Takigawa, M.8
-
19
-
-
0742321717
-
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma
-
DOI 10.1007/s00432-003-0500-4
-
Samantaray S, Sharma R, Chattopadhyaya TK, Gupta SD, Ralhan R. Increased expression of MMP2 and MMP9 in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol 2004; 130:37-44. (Pubitemid 38161246)
-
(2004)
Journal of Cancer Research and Clinical Oncology
, vol.130
, Issue.1
, pp. 37-44
-
-
Samantaray, S.1
Sharma, R.2
Chattopadhyaya, T.K.3
Datta, G.S.4
Ralhan, R.5
-
20
-
-
4944246547
-
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
-
DOI 10.1136/jcp.2003.015032
-
Greijer AE, van der Wall E. The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 2004; 57:1009-14. (Pubitemid 39331346)
-
(2004)
Journal of Clinical Pathology
, vol.57
, Issue.10
, pp. 1009-1014
-
-
Greijer, A.E.1
Van Der, W.E.2
-
22
-
-
37349002494
-
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226
-
DOI 10.1016/j.bcp.2007.08.011, PII S0006295207005527
-
Chen CJ, Hsu MH, Huang LJ, Yamori T, Chung JG, Lee FY, et al. Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226. Biochem Pharmacol 2008; 75:360-8. (Pubitemid 350298460)
-
(2008)
Biochemical Pharmacology
, vol.75
, Issue.2
, pp. 360-368
-
-
Chen, C.-J.1
Hsu, M.-H.2
Huang, L.-J.3
Yamori, T.4
Chung, J.-G.5
Lee, F.-Y.6
Teng, C.-M.7
Kuo, S.-C.8
-
23
-
-
42549131961
-
Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma
-
Lau CK, Yang ZF, Lam SP, Lam CT, Ngai P, Tam KH, et al. Inhibition of Stat3. activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma. Cancer Biol Ther 2007; 6:1900-7. (Pubitemid 351590402)
-
(2007)
Cancer Biology and Therapy
, vol.6
, Issue.12
, pp. 1900-1907
-
-
Chi, K.L.1
Zhen, F.Y.2
Shuk, P.L.3
Chi, T.L.4
Ngai, P.5
Ka, H.T.6
Poon, R.T.-P.7
Sheung, T.F.8
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