Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2

Biochemical and Biophysical Research Communications

Volumn 393, Issue 3, 2010, Pages 371-376

  Binker, Marcelo G ^a,b   Binker Cosen, Andres A ^b   Richards, Daniel ^b   Gaisano, Herbert Y ^a   de Cosen, Rodica H ^b   Cosen Binker, Laura I ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CBRHC Research Center   (Argentina)

Author keywords

Cancer invasion; Hypoxia reoxygenation; Matrix metalloproteinase 2 (MMP 2); PANC 1 cells; Rac1; Reactive oxygen species (ROS)

Indexed keywords

GELATINASE A; PHOSPHATIDYLINOSITOL 3 KINASE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BASEMENT MEMBRANE; CARCINOMA CELL; CELL HYPOXIA; CELL INVASION; CONTROLLED STUDY; DEGRADATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; REOXYGENATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL HYPOXIA; CELL LINE, TUMOR; HUMANS; MATRIX METALLOPROTEINASE 2; NADP; NEOPLASM INVASIVENESS; OXYGEN; PANCREATIC NEOPLASMS; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES;

EID: 77949273897     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.125     Document Type: Article

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