-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal A., Siegel R., Ward E., Murray T., Xu J., Smigal C., et al. Cancer statistics, 2006. CA Cancer J Clin 55 (2005) 106-130
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Smigal, C.6
-
3
-
-
9244222261
-
Targeted cancer therapy
-
Sawyers C. Targeted cancer therapy. Nature 432 (2004) 294-297
-
(2004)
Nature
, vol.432
, pp. 294-297
-
-
Sawyers, C.1
-
4
-
-
0028109332
-
YC-1, a novel activator of platelet guanylate cyclase
-
Ko F.N., Wu C.C., Kuo S.C., Lee F.Y., and Teng CM. YC-1, a novel activator of platelet guanylate cyclase. Blood 84 (1994) 4226-4233
-
(1994)
Blood
, vol.84
, pp. 4226-4233
-
-
Ko, F.N.1
Wu, C.C.2
Kuo, S.C.3
Lee, F.Y.4
Teng CM5
-
5
-
-
0029166002
-
YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase
-
Wu C.C., Ko F.N., Kuo S.C., Lee F.Y., and Teng C.M. YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase. Br J Pharmacol 116 (1995) 1973-1978
-
(1995)
Br J Pharmacol
, vol.116
, pp. 1973-1978
-
-
Wu, C.C.1
Ko, F.N.2
Kuo, S.C.3
Lee, F.Y.4
Teng, C.M.5
-
6
-
-
0031565271
-
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice
-
Teng C.M., Wu C.C., Ko F.N., Lee F.Y., and Kuo S.C. YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice. Eur J Pharmacol 320 (1997) 161-166
-
(1997)
Eur J Pharmacol
, vol.320
, pp. 161-166
-
-
Teng, C.M.1
Wu, C.C.2
Ko, F.N.3
Lee, F.Y.4
Kuo, S.C.5
-
7
-
-
0032211767
-
Stimulation of soluble guanylate cyclase by superoxide dismutase is mediated by NO
-
Friebe A., Schultz G., and Koesling D. Stimulation of soluble guanylate cyclase by superoxide dismutase is mediated by NO. Biochem J 335 (1998) 527-531
-
(1998)
Biochem J
, vol.335
, pp. 527-531
-
-
Friebe, A.1
Schultz, G.2
Koesling, D.3
-
8
-
-
1842525176
-
Versatile pharmacological actions of YC-1: anti-platelet to anticancer
-
Chun Y.S., Yeo E.J., and Park J.W. Versatile pharmacological actions of YC-1: anti-platelet to anticancer. Cancer Lett 207 (2004) 1-7
-
(2004)
Cancer Lett
, vol.207
, pp. 1-7
-
-
Chun, Y.S.1
Yeo, E.J.2
Park, J.W.3
-
9
-
-
14344254896
-
YC-1 [3-(5′-Hydroxymethyl-2′-furyl)-1-benzyl Indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G0-G1 in human hepatocellular carcinoma cells
-
Wang S.W., Pan S.L., Guh J.H., Chen H.L., Huang D.M., Chang Y.L., et al. YC-1 [3-(5′-Hydroxymethyl-2′-furyl)-1-benzyl Indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G0-G1 in human hepatocellular carcinoma cells. J Pharmacol Exp Ther 312 (2005) 917-925
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 917-925
-
-
Wang, S.W.1
Pan, S.L.2
Guh, J.H.3
Chen, H.L.4
Huang, D.M.5
Chang, Y.L.6
-
10
-
-
33745728147
-
YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases
-
Yeo E.J., Ryu J.H., Chun Y.S., Cho Y.S., Jang I.J., Cho H., et al. YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases. Cancer Res 66 (2006) 6345-6352
-
(2006)
Cancer Res
, vol.66
, pp. 6345-6352
-
-
Yeo, E.J.1
Ryu, J.H.2
Chun, Y.S.3
Cho, Y.S.4
Jang, I.J.5
Cho, H.6
-
11
-
-
23044433522
-
YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models
-
Pan S.L., Guh J.H., Peng C.Y., Wang S.W., Chang Y.L., Cheng F.C., et al. YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models. J Pharmacol Exp Ther 314 (2005) 35-42
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 35-42
-
-
Pan, S.L.1
Guh, J.H.2
Peng, C.Y.3
Wang, S.W.4
Chang, Y.L.5
Cheng, F.C.6
-
12
-
-
18844366701
-
A potential role of YC-1 on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models
-
Pan S.L., Guh J.H., Peng C.Y., Chang Y.L., Cheng F.C., Chang J.H., et al. A potential role of YC-1 on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models. Thromb Haemost 93 (2005) 940-948
-
(2005)
Thromb Haemost
, vol.93
, pp. 940-948
-
-
Pan, S.L.1
Guh, J.H.2
Peng, C.Y.3
Chang, Y.L.4
Cheng, F.C.5
Chang, J.H.6
-
13
-
-
29244492264
-
YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits neointima formation in balloon-injured rat carotid through suppression of expressions and activities of matrix metal-oproteinases 2 and 9
-
Liu Y.N., Pan S.L., Peng C.Y., Guh J.H., Huang D.M., Chang Y.L., et al. YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits neointima formation in balloon-injured rat carotid through suppression of expressions and activities of matrix metal-oproteinases 2 and 9. J Pharmacol Exp Ther 316 (2006) 35-41
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 35-41
-
-
Liu, Y.N.1
Pan, S.L.2
Peng, C.Y.3
Guh, J.H.4
Huang, D.M.5
Chang, Y.L.6
-
14
-
-
27644518437
-
YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells
-
Huang Y.T., Pan S.L., Guh J.H., Chang Y.L., Lee F.Y., Kuo S.C., et al. YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells. Mol Cancer Ther 4 (2005) 1628-1635
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1628-1635
-
-
Huang, Y.T.1
Pan, S.L.2
Guh, J.H.3
Chang, Y.L.4
Lee, F.Y.5
Kuo, S.C.6
-
15
-
-
0024312538
-
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm
-
Paull K.D., Shoemaker R.H., Hodes L., Monks A., Scudiero D.A., Rubinstein L., et al. Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm. J Natl Cancer Inst 81 (1989) 1088-1092
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1088-1092
-
-
Paull, K.D.1
Shoemaker, R.H.2
Hodes, L.3
Monks, A.4
Scudiero, D.A.5
Rubinstein, L.6
-
16
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks A., Scudiero D., Skehan P., Shoemaker R., Paull K., Vistica D., et al. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst 83 (1991) 757-766
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
Shoemaker, R.4
Paull, K.5
Vistica, D.6
-
17
-
-
0033566690
-
Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel
-
Yamori T., Matsunaga A., Sato S., Yamazaki K., Komi A., Ishizu K., et al. Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel. Cancer Res 59 (1999) 4042-4049
-
(1999)
Cancer Res
, vol.59
, pp. 4042-4049
-
-
Yamori, T.1
Matsunaga, A.2
Sato, S.3
Yamazaki, K.4
Komi, A.5
Ishizu, K.6
-
18
-
-
0042827269
-
Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics
-
Yamori T. Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics. Cancer Chemother Pharmacol 52 1 (2003) S74-S79
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, Issue.1
-
-
Yamori, T.1
-
19
-
-
0033604557
-
New insights into the control of MAP kinase pathways
-
English J., Pearson G., Wilsbacher J., Swantek J., Karandikar M., Xu S., et al. New insights into the control of MAP kinase pathways. Exp Cell Res 253 (1999) 255-270
-
(1999)
Exp Cell Res
, vol.253
, pp. 255-270
-
-
English, J.1
Pearson, G.2
Wilsbacher, J.3
Swantek, J.4
Karandikar, M.5
Xu, S.6
-
20
-
-
0035525733
-
Cellular stress response and apoptosis in cancer therapy
-
Herr I., and Debatin K.M. Cellular stress response and apoptosis in cancer therapy. Blood 98 (2001) 2603-2614
-
(2001)
Blood
, vol.98
, pp. 2603-2614
-
-
Herr, I.1
Debatin, K.M.2
-
21
-
-
0035073292
-
Phosphorylation of Bcl-2 and regulation of apoptosis
-
Ruvolo P.P., Deng X., and May W.S. Phosphorylation of Bcl-2 and regulation of apoptosis. Leukemia 15 (2001) 515-522
-
(2001)
Leukemia
, vol.15
, pp. 515-522
-
-
Ruvolo, P.P.1
Deng, X.2
May, W.S.3
-
22
-
-
0033995511
-
Antiangiogenic strategies and agents in clinical trials
-
Rosen L. Antiangiogenic strategies and agents in clinical trials. Oncologist 5 (2000) 20-27
-
(2000)
Oncologist
, vol.5
, pp. 20-27
-
-
Rosen, L.1
-
23
-
-
0034956272
-
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis
-
John A., and Tuszynski G. The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. Pathol Oncol Res 7 (2001) 14-23
-
(2001)
Pathol Oncol Res
, vol.7
, pp. 14-23
-
-
John, A.1
Tuszynski, G.2
-
24
-
-
0034783705
-
Prolonged exposure to YC-1 induces apoptosis in adreno-medullary endothelial and chromaffin cells through a cGMP-independent mechanism
-
Ferrero R., and Torres M. Prolonged exposure to YC-1 induces apoptosis in adreno-medullary endothelial and chromaffin cells through a cGMP-independent mechanism. Neuropharmacology 41 (2001) 895-906
-
(2001)
Neuropharmacology
, vol.41
, pp. 895-906
-
-
Ferrero, R.1
Torres, M.2
-
25
-
-
0037414180
-
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1
-
Yeo E.J., Chun Y.S., Cho Y.S., Kim J., Lee J.C., Kim M.S., et al. YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 95 (2003) 516-525
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 516-525
-
-
Yeo, E.J.1
Chun, Y.S.2
Cho, Y.S.3
Kim, J.4
Lee, J.C.5
Kim, M.S.6
-
26
-
-
0034612236
-
Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1
-
Zhang Y., Griffith E.C., Sage J., Jacks T., and Liu J.O. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proc Natl Acad Sci USA 97 (2000) 6427-6432
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6427-6432
-
-
Zhang, Y.1
Griffith, E.C.2
Sage, J.3
Jacks, T.4
Liu, J.O.5
-
27
-
-
0032529455
-
Suppression of hepatoma growth and angiogenesis by a fumagillin derivative TNP470: possible involvement of nitric oxide synthase
-
Yoshida T., Kaneko Y., Tsukamoto A., Han K., Ichinose M., and Kimura S. Suppression of hepatoma growth and angiogenesis by a fumagillin derivative TNP470: possible involvement of nitric oxide synthase. Cancer Res 58 (1998) 3751-3756
-
(1998)
Cancer Res
, vol.58
, pp. 3751-3756
-
-
Yoshida, T.1
Kaneko, Y.2
Tsukamoto, A.3
Han, K.4
Ichinose, M.5
Kimura, S.6
-
28
-
-
6544276582
-
A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer
-
Bhargava P., Marshall J.L., Rizvi N., Dahut W., Yoe J., Figuera M., et al. A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer. Clin Cancer Res 5 (1999) 1989-1995
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1989-1995
-
-
Bhargava, P.1
Marshall, J.L.2
Rizvi, N.3
Dahut, W.4
Yoe, J.5
Figuera, M.6
|