Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning

Toxicology

Volumn 285, Issue 3, 2011, Pages 90-96

  Lundy, Paul M ^a   Hamilton, Murray G ^b   Sawyer, Thomas W ^c   Mikler, John ^c  

^a Therapeutic Response Ltd   (Canada)

^b Knotox Inc   (United States)

^c DEFENCE RESEARCH AND DEVELOPMENT CANADA   (Canada)

Author keywords

Chemical warfare (CW) agents; HI 6: 1 4 (aminocarbonyl) pyridinio methoxy methyl 2 (hydroxyimino) methyl pyridinium dichloride, CAS 34433 31 3; MMB 4: methoxime, ICD 039, 1,1' trimethylene bis 4 (hydroxyimino)methyl pyridinium dibromide, CAS 2058 89 1; Organophosphorous (OP) nerve agents; Therapy

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1,1' METHYLENEBIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) DICHLORIDE; CHEMICAL WARFARE AGENT; NERVE GAS; OBIDOXIME; ORGANOPHOSPHATE INSECTICIDE; PRALIDOXIME;

CHEMICAL WARFARE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; ENZYME REACTIVATION; HUMAN; INTOXICATION; LD 50; NONHUMAN; PRIORITY JOURNAL; PROTECTION; REVIEW;

ANTIDOTES; CHEMICAL WARFARE AGENTS; HUMANS; ORGANOPHOSPHORUS COMPOUNDS; OXIMES; PHOSPHORIC ACID ESTERS; PYRIDINIUM COMPOUNDS; SARIN; SOMAN;

PRIMATES;

EID: 79957790610     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.04.006     Document Type: Review

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