Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose Reactivation of nerve agent-inhibited AChE by oximes Tsung-Ming Shih et al.

Toxicology Mechanisms and Methods

Volumn 19, Issue 6-7, 2009, Pages 386-400

  Shih, Tsung Ming ^a   Skovira, Jacob W ^a   O'Donnell, John C ^a   McDonough, John H ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Acetylcholinesterase; Cholinesterase inhibitors; Cholinesterase reactivation; Cyclosarin; Guinea pig; HI 6; HL 7; Methoxime; Nerve agents; Organophosphorus compounds; Oximes; Pralidoxime; Sarin; Trimedoxime; VR; VX

Indexed keywords

1 (4 AMINOCARBONYLPYRIDINIO) 3 (2 HYDROXYIMINOMETHYLPYRIDINIO)PROPANE; 1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 [1 (2 HYDROXYIMINOMETHYL 3 METHYL)IMIDAZOLO] 3 [4 CARBAMOYLPYRIDINIUM]PROPANE; 1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; 1,1' METHYLENEBIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) DICHLORIDE; 3 [4 CARBAMOYL 1 PYRIDINO] 1 [2,4 BIS(HYDROXYIMINOMETHYL) 1 PYRIDINO]PROPANE; ACETYLCHOLINESTERASE; CARBOXIME; CYCLOSARIN; ICD 3805; ICD 585; ICD 692; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; ORGANOPHOSPHORUS COMPOUND; OXIME; PRALIDOXIME; SARIN; TRIMEDOXIME; UNCLASSIFIED DRUG; VR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; GUINEA PIG; IN VIVO STUDY; LETHAL DOSE; LETHALITY; MALE; NONHUMAN; PRIORITY JOURNAL; TISSUE;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DIAPHRAGM; ERYTHROCYTES; GUINEA PIGS; HUMANS; MALE; MOLECULAR STRUCTURE; MUSCLE, SKELETAL; MYOCARDIUM; ORGANOPHOSPHORUS COMPOUNDS; OXIMES; TISSUE DISTRIBUTION;

ANIMALIA; CAVIA;

EID: 70350436641     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510903213892     Document Type: Article

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