Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19381-19391

  Mao, Pingping ^a   Hever, Mary P ^a   Niemaszyk, Lynne M ^a   Haghkerdar, Jessica M ^a   Yanco, Esty G ^a   Desai, Damayanti ^a   Beyrouthy, Maroun J ^a   Kerley Hamilton, Joanna S ^a   Freemantle, Sarah J ^a   Spinella, Michael J ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC CELL DEATH; CANCER CELLS; CELL LINES; CELLULAR REACTIVE OXYGEN SPECIES; CIS-PLATIN; DEATH-ASSOCIATED PROTEINS; GROWTH SUPPRESSIONS; HUMAN CELLS; METALLOTHIONEINS; MOUSE GENOME; OVER-EXPRESSION; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; TARGET GENES; THREONINE KINASE; TRANSCRIPTIONAL RESPONSE; UP-REGULATION;

AMINO ACIDS; CELL CULTURE; CELL DEATH; DISEASES; ENZYMES; GENE THERAPY; OXYGEN; TOXICITY;

PLATINUM COMPOUNDS;

CISPLATIN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; SERINE THREONINE KINASE 17A; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG CYTOTOXICITY; ENZYME INDUCTION; GENE; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; MT1H GENE; MT1M GENE; MT1X GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; STK17A GENE; TESTIS CANCER; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, EMBRYONAL; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; METALLOTHIONEIN; MICE; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SPECIES SPECIFICITY; TESTICULAR NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79957619020     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.218040     Document Type: Article

References (52)

1. Zilfou, J. T., and Lowe, S. W. (2009) Cold Spring Harb. Perspect. Biol. 1, a001883
2. Gottlieb, E., and Vousden, K. H. (2010) Cold Spring Harb. Perspect. Biol. 2, a001040
3. Beckerman, R., and Prives, C. (2010) Cold Spring Harb. Perspect. Biol. 2, a000935
4. Einhorn, L. H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 4592-4595
5. Houldsworth, J., Korkola, J. E., Bosl, G. J., and Chaganti, R. S. (2006) J. Clin. Oncol. 24, 5512-5518
6. Giuliano, C. J., Freemantle, S. J., and Spinella, M. J. (2006) Curr. Cancer Ther. Rev. 2, 255-270
7. Peng, H. Q., Hogg, D., Malkin, D., Bailey, D., Gallie, B. L., Bulbul, M., Jewett, M., Buchanan, J., and Goss, P. E. (1993) Cancer Res. 53, 3574-3578
8. Lutzker, S. G., and Levine, A. J. (1996) Nat. Med. 2, 804-810
9. Kerley-Hamilton, J. S., Pike, A. M., Li, N., DiRenzo, J., and Spinella, M. J. (2005) Oncogene 24, 6090-6100
10. Bialik, S., and Kimchi, A. (2006) Annu. Rev. Biochem. 75, 189-210
11. Lin, Y., Hupp, T. R., and Stevens, C. (2010) FEBS J. 277, 48-57
12. Michie, A. M., McCaig, A. M., Nakagawa, R., and Vukovic, M. (2010) FASEB J. 277, 74-80
13. Sanjo, H., Kawai, T., and Akira, S. (1998) J. Biol. Chem. 273, 29066-29071
14. Fitzgerald, J., and Bateman, J. F. (2004) Trends Genet. 20, 408-412
15. McGargill, M. A., Wen, B. G., Walsh, C. M., and Hedrick, S. M. (2004) Immunity 21, 781-791
16. Gatzka, M., Newton, R. H., and Walsh, C. M. (2009) J. Immunol. 183, 285-297
17. Curtin, J. C., Dragnev, K. H., Sekula, D., Christie, A. J., Dmitrovsky, E., and Spinella, M. J. (2001) Oncogene 20, 2559-2569
18. Levesque, A. A., Kohn, E. A., Bresnick, E., and Eastman, A. (2005) Oncogene 24, 3786-3796
19. Liu, X., Sempere, L. F., Galimberti, F., Freemantle, S. J., Black, C., Dragnev, K. H., Ma, Y., Fiering, S., Memoli, V., Li, H., DiRenzo, J., Korc, M., Cole, C. N., Bak, M., Kauppinen, S., and Dmitrovsky, E. (2009) Clin. Cancer Res. 15, 1177-1183
20. Beyrouthy, M. J., Garner, K. M., Hever, M. P., Freemantle, S. J., Eastman, A., Dmitrovsky, E., and Spinella, M. J. (2009) Cancer Res. 69, 9360-9366
21. Kerley-Hamilton, J. S., Pike, A. M., Hutchinson, J. A., Freemantle, S. J., and Spinella, M. J. (2007) Biochim. Biophys. Acta 1769, 209-219
22. Hoh, J., Jin, S., Parrado, T., Edington, J., Levine, A. J., and Ott, J. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 8467-8472
23. Wei, C. L., Wu, Q., Vega, V. B., Chiu, K. P., Ng, P., Zhang, T., Shahab, A., Yong, H. C., Fu, Y., Weng, Z., Liu, J., Zhao, X. D., Chew, J. L., Lee, Y. L., Kuznetsov, V. A., Sung, W. K., Miller, L. D., Lim, B., Liu, E. T., Yu, Q., Ng, H. H., and Ruan, Y. (2006) Cell 124, 207-219
24. Spierings, D. C., de Vries, E. G., Vellenga, E., and de Jong, S. (2003) J. Pathol. 200, 137-148
25. Knipp, M. (2009) Curr. Med. Chem. 16, 522-537
26. Chang, T. S., Cho, C. S., Park, S., Yu, S., Kang, S. W., and Rhee, S. G. (2004) J. Biol. Chem. 279, 41975-41984
27. Boswell, S. A., Ongusaha, P. P., Nghiem, P., and Lee, S. W. (2007) J. Biol. Chem. 282, 4850-4858
28. Hu, W., Zhang, C., Wu, R., Sun, Y., Levine, A., and Feng, Z. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 7455-7460
29. Suzuki, S., Tanaka, T., Poyurovsky, M. V., Nagano, H., Mayama, T., Ohkubo, S., Lokshin, M., Hosokawa, H., Nakayama, T., Suzuki, Y., Sugano, S., Sato, E., Nagao, T., Yokote, K., Tatsuno, I., and Prives, C. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 7461-7466
30. Bensaad, K., Tsuruta, A., Selak, M. A., Vidal, M. N., Nakano, K., Bartrons, R., Gottlieb, E., and Vousden, K. H. (2006) Cell 126, 107-120
31. Crighton, D., Wilkinson, S., O'Prey, J., Syed, N., Smith, P., Harrison, P. R., Gasco, M., Garrone, O., Crook, T., and Ryan, K. M. (2006) Cell 126, 121-134
32. Zhang, Y., Qian, Y., Lu, W., and Chen, X. (2009) Cancer Res. 69, 6049-6056
33. Kawase, T., Ohki, R., Shibata, T., Tsutsumi, S., Kamimura, N., Inazawa, J., Ohta, T., Ichikawa, H., Aburatani, H., Tashiro, F., and Taya, Y. (2009) Cell 136, 535-550
34. Li, J., Tan, J., Zhuang, L., Banerjee, B., Yang, X., Chau, J. F., Lee, P. L., Hande, M. P., Li, B., and Yu, Q. (2007) Cancer Res. 67, 11317-11326
35. He, H., and Sun, Y. (2007) Oncogene 26, 2707-2716
36. Kortlever, R. M., Higgins, P. J., and Bernards, R. (2006) Nat. Cell Biol. 8, 877-884
37. Yu, X., Riley, T., and Levine, A. J. (2009) FEBS J. 276, 2201-2212
38. Masters, J. R., and Köberle, B. (2003) Nat. Rev. Cancer 3, 517-525
39. Tang, H., Liu, Y. J., Liu, M., and Li, X. (2007) Anticancer Drugs 18, 633-639
40. Wittig, R., Nessling, M., Will, R. D., Mollenhauer, J., Salowsky, R., Münstermann, E., Schick, M., Helmbach, H., Gschwendt, B., Korn, B., Kioschis, P., Lichter, P., Schadendorf, D., and Poustka, A. (2002) Cancer Res. 62, 6698-6705
41. Inbal, B., Cohen, O., Polak-Charcon, S., Kopolovic, J., Vadai, E., Eisenbach, L., and Kimchi, A. (1997) Nature 390, 180-184
42. Raveh, T., Droguett, G., Horwitz, M. S., DePinho, R. A., and Kimchi, A. (2001) Nat. Cell Biol. 3, 1-7
43. Gozuacik, D., Bialik, S., Raveh, T., Mitou, G., Shohat, G., Sabanay, H., Mizushima, N., Yoshimori, T., and Kimchi, A. (2008) Cell Death Differ. 15, 1875-1886
44. Harrison, B., Kraus, M., Burch, L., Stevens, C., Craig, A., Gordon-Weeks, P., and Hupp, T. R. (2008) J. Biol. Chem. 283, 9999-10014
45. Gozuacik, D., and Kimchi, A. (2006) Autophagy 2, 74-79
46. Martoriati, A., Doumont, G., Alcalay, M., Bellefroid, E., Pelicci, P. G., and Marine, J. C. (2005) Oncogene 24, 1461-1466
47. Kuwahara, H., Nakamura, N., and Kanazawa, H. (2006) Biol. Pharm. Bull. 29, 225-233
48. Mao, J., Qiao, X., Luo, H., and Wu, J. (2006) J. Biol. Chem. 281, 12587-12595
49. Brozovic, A., Ambrioviæ-Ristov, A., and Osmak, M. (2010) Crit. Rev. Toxicol. 40, 347-359
50. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., and Vogelstein, B. (1997) Nature 389, 300-305
51. Hwang, P. M., Bunz, F., Yu, J., Rago, C., Chan, T. A., Murphy, M. P., Kelso, G. F., Smith, R. A., Kinzler, K. W., and Vogelstein, B. (2001) Nat. Med. 7, 1111-1117
52. Faraonio, R., Vergara, P., Di Marzo, D., Pierantoni, M. G., Napolitano, M., Russo, T., and Cimino, F. (2006) J. Biol. Chem. 281, 39776-39784