Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints

Oncogene

Volumn 24, Issue 23, 2005, Pages 3786-3796

  Levesque, Aime A ^a,b   Kohn, Ethan A ^a,b   Bresnick, Edward ^a,b   Eastman, Alan ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b NORRIS COTTON CANCER CENTER   (United States)

Author keywords

Cell cycle checkpoints; Cyclin B; p53 tumor suppressor; Topoisomerase I inhibitors; UCN 01

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 HYDROXYSTAUROSPORINE; CHECKPOINT KINASE 1; CYCLIN B; PROTEIN P21; PROTEIN P53; SHORT HAIRPIN RNA; 7-ETHYL-10-HYDROXYCAMPTOTHECIN; 7-HYDROXYSTAUROSPORINE; CAMPTOTHECIN; CDC25A PROTEIN; DRUG DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE; REPRESSOR PROTEIN; STAUROSPORINE;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; DRUG INHIBITION; DRUG MECHANISM; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TRANSACTIVATION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENETICS; PHYSIOLOGY; TUMOR CELL LINE;

CAMPTOTHECIN; CDC25 PHOSPHATASE; CELL LINE, TUMOR; CYCLIN B; DNA DAMAGE; FEMALE; G2 PHASE; HUMANS; REPRESSOR PROTEINS; S PHASE; STAUROSPORINE; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 19844373994     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208451     Document Type: Article

References (42)

1. Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y and Ziv Y. (1998). Science, 281, 1674-1677.
2. Bunch RT and Eastman A. (1996). Clin. Cancer Res., 2, 791-797.
3. Canman CE, Lim D-S, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB and Siliciano JD. (1998). Science, 281, 1677-1679.
4. Curtin JC, Dragnev KH, Sekula D, Christie AJ, Dmitrovsky E and Spinella MJ. (2001). Oncogene, 20, 2559-2569.
5. Damia G, Sanchez Y, Erba E and Broggini M. (2001). J. Biol. Chem., 276, 10641-10645.
6. Demarcq C, Bunch RT, Creswell D and Eastman A. (1994). Cell Growth Differ., 5, 983-993.
7. Falck J, Mailand N, Syljuasen RG, Bartek J and Lukas J. (2001). Nature, 410, 842-847.
8. Fan S, Smith ML, Rivet DJ, Duba D, Zhan Q, Kohn KW, Fornace AJ and O'Connor PM. (1995). Cancer Res., 55, 1649-1654.
9. Flatt PM, Tang LJ, Scatena CD, Szak ST and Pietenpol JA. (2000). Mol. Cell. Biol., 20, 4210-4223.
10. Gorczyca W, Sarode V, Juan G, Melamed MR and Darzynkiewicz Z. (1997). Mod Pathol., 10, 457-462.
11. Haupt Y, Maya R, Kazaz A and Oren M. (1997). Nature, 387, 296-299.
12. Hengstschlager M, Braun K, Soucek T, Miloloza A and Hengstschlager-Ottnad E. (1999). Mutat. Res., 436, 1-9.
13. Hirao A, Kong Y-Y, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ and Mak TW. (2000). Science, 287, 1824-1827.
14. Hirose Y, Berger MS and Pieper RO. (2001). Cancer Res., 61, 5843-5849.
15. Ho J and Benchimol S. (2003). Cell Death Differ., 10, 404-408.
16. Husain A, Yan X-J, Resales N, Aghajanian C, Schwartz GK and Spriggs DR. (1997). Clin. Cancer Res., 3, 2089-2097.
17. Johnson RA, Ince TA and Scotto KW. (2001). J. Biol. Chem., 276, 27716-27720.
18. Kitaura H, Shinshi M, Uchikoshi Y, Ono T, Tsurimoto T, Yoshikawa H, Iguchi-ariga SMM and Ariga H. (2000). J. Biol. Chem., 275, 10477-10483.
19. Kohn EA, Ruth ND, Brown MK, Livingstone M and Eastman A. (2002). J. Biol. Chem., 277, 26553-26564.
20. Kohn EA, Yoo CJ and Eastman A. (2003). Cancer Res., 63, 31-35.
21. Kubbutat MH, Jones SN and Vousden KH. (1997). Nature, 387, 299-303.
22. Lau CC and Pardee AB. (1982). Proc. Natl. Acad. Sci. USA, 79, 2942-2946.
23. Mailand N. Falck J, Lukas C. Syljuasen RG, Welcher M, Bartek J and Lukas J. (2000). Science, 288, 1425-1429.
24. Manni I, Mazzaro G, Gurtner A. Mantovani R, Haugwitz U, Krause K, Engeland K, Sacchi A, Soddu S and Piaggio G. (2001). J. Biol. Chem., 276, 5570-5576.
25. Matsuoka S, Huang M and Elledge SJ. (1998). Science, 282, 1893-1897.
26. Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K and Elledge SJ. (2000). Proc. Natl. Acad. Sci. USA, 97, 10389-10394.
27. Ossovskaya VS. Mazo IA, Chernov MV, Strezoska Z, Kondratov R, Stark GR, Chumakov PM and Gudkov AV. (1996). Proc. Natl. Acad. Sci. USA, 93, 10309-10314.
28. Park M, Chae H-D, Yun J, Jung M, Kim Y-S, Kim S-H, Han MH and Shin DY. (2000). Cancer Res., 60, 542-545.
29. Powell SN, DeFrank JS, Connell P, Eogan M, Preffer F, Dombkowski D, Tang W and Friend S. (1995). Cancer Res., 55, 1643-1648.
30. Russell KJ, Wiens LW, Demers GW, Galloway DA, Plon SE and Groudine M. (1995). Cancer Res., 55, 1639-1642.
31. Sagata N. (2002). Science, 298, 1905-1907.
32. Santoni-rugiu E, Falck J, Mailand N, Bartek J and Lukas J. (2000). Mol. Cell. Biol., 20, 3497-3509.
33. Schlegel R and Pardee AB. (1986). Science, 232, 1264-1266.
34. Schwarz JK, Lovly CM and Piwnica-Worms H. (2003). Mol. Cancer Res., 1, 598-609.
35. Shao R-G, Cao C-X, Shimizu T, O'Connor PM, Kohn KW and Pommier Y. (1997). Cancer Res., 57, 4029-4035.
36. Shieh S-Y, Ahn J, Tamai K, Taya Y and Prives C. (2000). Genes Dev., 14, 289-300.
37. Vigo E, Muller H, Prosperini E, Hateboer G, Cartwright P, Moroni MC and Helin K. (1999). Mol. Cell. Biol., 19, 6379-6395.
38. Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA and O'Connor PM. (1996). J. Natl. Cancer Inst., 88, 956-965.
39. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R and Beach D. (1993). Nature, 366, 701-704.
40. Zeng Y, Forbes KC, Wu Z, Moreno S, Piwnica-Worms H and Enoch T. (1998). Nature, 395, 507-510.
41. Zhao H and Piwnica-Worms H. (2001). Mol. Cell. Biol., 21, 4129-4139.
42. Zhao H, Watkins JL and Piwnica-Worms H. (2002). Proc. Natl. Acad. Sci. USA, 99, 14795-14800.