The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19641-19651

  Tarallo, Valeria ^a   Lepore, Laura ^b   Marcellini, Marcella ^c   Dal Piaz, Fabrizio ^b   Tudisco, Laura ^a   Ponticelli, Salvatore ^a   Lund, Frederik Wendelboe ^d   Roepstorff, Peter ^d   Orlandi, Augusto ^e   Pisano, Claudio ^c   De Tommasi, Nunziatina ^b   De Falco, Sandro ^a  

^a INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c Research and Development Oncology Area   (Italy)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTIANGIOGENIC; BIOACTIVE MOLECULES; CHORIO-ALLANTOIC MEMBRANES; COLON CARCINOMA; FUNCTIONAL RELATIONSHIP; GROWTH FACTOR; IN-VIVO; ISOLATION AND IDENTIFICATION; NEOVASCULARIZATION; SMALL MOLECULES; STRUCTURAL STUDIES; TUBE FORMATION; TUMOR GROWTH; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGFR-2;

CYTOLOGY; ENDOTHELIAL CELLS; MOLECULES; PEPTIDES; PHOSPHORYLATION;

PLANT EXTRACTS;

AMENTOFLAVONE; PLACENTAL GROWTH FACTOR; PLACENTAL GROWTH FACTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER MODEL; CAPILLARY; CELL MIGRATION; CHORIOALLANTOIS; CHROZOPHORA SENEGALENSIS; COLON CARCINOMA; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MALE; MEDICINAL PLANT; MELANOMA; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TUMOR VASCULARIZATION; TUMOR XENOGRAFT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIFLAVONOIDS; COLONIC NEOPLASMS; HEK293 CELLS; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; XENOGRAFT MODEL ANTITUMOR ASSAYS;

CHROZOPHORA; MALIA;

EID: 79957590393     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.186239     Document Type: Article

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