메뉴 건너뛰기




Volumn 50, Issue 3, 2011, Pages 278-301

Lipidomics of human Meibomian gland secretions: Chemistry, biophysics, and physiological role of Meibomian lipids

Author keywords

Bioanalytical chemistry; Human meibum; Lipids; Moss spectrometry; Tear film; Tear film layer

Indexed keywords

CHOLESTEROL ESTER; FATTY ACID; GLYCEROL; HYDROXY FATTY ACID; LIPID; MEIBOMIAN LIPID; PHOSPHOLIPID; UNCLASSIFIED DRUG;

EID: 79957546505     PISSN: 01637827     EISSN: 18732194     Source Type: Journal    
DOI: 10.1016/j.plipres.2011.03.003     Document Type: Review
Times cited : (105)

References (150)
  • 1
    • 47949101473 scopus 로고    scopus 로고
    • Classification and diagnosis of dry eye
    • T. Kaercher, and A.J. Bron Classification and diagnosis of dry eye Dev Ophthalmol 41 2008 36 53
    • (2008) Dev Ophthalmol , vol.41 , pp. 36-53
    • Kaercher, T.1    Bron, A.J.2
  • 2
    • 47949128479 scopus 로고    scopus 로고
    • The normal tear film
    • J.M. Tiffany The normal tear film Dev Ophthalmol 41 2008 1 20
    • (2008) Dev Ophthalmol , vol.41 , pp. 1-20
    • Tiffany, J.M.1
  • 3
    • 58149131710 scopus 로고    scopus 로고
    • Role of lactoferrin in the tear film
    • J.L. Flanagan, and M.D. Willcox Role of lactoferrin in the tear film Biochimie 91 2009 35 43
    • (2009) Biochimie , vol.91 , pp. 35-43
    • Flanagan, J.L.1    Willcox, M.D.2
  • 4
    • 1642445597 scopus 로고    scopus 로고
    • The Repeatability of Clinical Measurements of Dry Eye
    • DOI 10.1097/00003226-200404000-00010
    • K.K. Nichols, G.L. Mitchell, and K. Zadnik The repeatability of clinical measurements of dry eye Cornea 23 2004 272 285 (Pubitemid 38404279)
    • (2004) Cornea , vol.23 , Issue.3 , pp. 272-285
    • Nichols, K.K.1    Mitchell, G.L.2    Zadnik, K.3
  • 9
    • 67650540276 scopus 로고
    • Ricerche microchimiche sulla secrezione delle ghiandole sebacee palpebrali
    • O. Pes Ricerche microchimiche sulla secrezione delle ghiandole sebacee palpebrali Arch Ottalmol 5 1897 82 91
    • (1897) Arch Ottalmol , vol.5 , pp. 82-91
    • Pes, O.1
  • 10
    • 0001451485 scopus 로고
    • The Meibomian glands: An investigation into the secretion and some aspects of the physiology
    • R.G. Linton, D.H. Curnow, and W.J. Riley The Meibomian glands: an investigation into the secretion and some aspects of the physiology Br J Ophthalmol 45 1961 718 723
    • (1961) Br J Ophthalmol , vol.45 , pp. 718-723
    • Linton, R.G.1    Curnow, D.H.2    Riley, W.J.3
  • 11
    • 76549224067 scopus 로고
    • The precorneal film. Biomicroscopical, histological and chemical investigations
    • N. Ehlers The precorneal film. Biomicroscopical, histological and chemical investigations Acta Ophthalmol Suppl 81 Suppl. 1965 1 134
    • (1965) Acta Ophthalmol Suppl , vol.81 , Issue.SUPPL. , pp. 1-134
    • Ehlers, N.1
  • 12
    • 0023489397 scopus 로고
    • The lipid secretion of the Meibomian glands
    • J.M. Tiffany The lipid secretion of the Meibomian glands Adv Lipid Res 22 1987 1 62
    • (1987) Adv Lipid Res , vol.22 , pp. 1-62
    • Tiffany, J.M.1
  • 13
    • 79958829280 scopus 로고    scopus 로고
    • In search for a better animal model of human tear film: Comparative lipidomic analysis of human and animal meibum
    • I.A. Butovich, and T.J. Millar In search for a better animal model of human tear film: comparative lipidomic analysis of human and animal meibum Invest Ophthalmol Vis Sci 50 2009 2545 [E-Abstract]
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 2545
    • Butovich, I.A.1    Millar, T.J.2
  • 14
    • 0002762554 scopus 로고    scopus 로고
    • Structure and function of the eyelids and conjunctiva
    • A.W. Lawton Structure and function of the eyelids and conjunctiva H.E. Kaufman, B.A. Barron, M.B. McDonald, The Cornea 2nd ed. 1998 Butterworth-Heonemann Boston, Oxford, Johannesburg, Melbourne, New Delhi, Singapore 55 56
    • (1998) The Cornea , pp. 55-56
    • Lawton, A.W.1
  • 15
    • 68849088948 scopus 로고    scopus 로고
    • Tear and Meibomian gland function in blepharitis and normals
    • L.C. McCann, A. Tomlinson, E.I. Pearce, and C. Diaper Tear and Meibomian gland function in blepharitis and normals Eye Contact Lens 35 2009 203 208
    • (2009) Eye Contact Lens , vol.35 , pp. 203-208
    • McCann, L.C.1    Tomlinson, A.2    Pearce, E.I.3    Diaper, C.4
  • 16
    • 42649122972 scopus 로고    scopus 로고
    • Noncontact Infrared Meibography to Document Age-Related Changes of the Meibomian Glands in a Normal Population
    • DOI 10.1016/j.ophtha.2007.06.031, PII S0161642007007282
    • R. Arita, K. Itoh, K. Inoue, and S. Amano Noncontact infrared meibography to document age-related changes of the Meibomian glands in a normal population Ophthalmology 115 2008 911 915 (Pubitemid 351602287)
    • (2008) Ophthalmology , vol.115 , Issue.5 , pp. 911-915
    • Arita, R.1    Itoh, K.2    Inoue, K.3    Amano, S.4
  • 17
    • 0036786796 scopus 로고    scopus 로고
    • Anatomy and histopathology of human Meibomian gland
    • H. Obata Anatomy and histopathology of human Meibomian gland Cornea 21 2002 S70 S74
    • (2002) Cornea , vol.21
    • Obata, H.1
  • 19
    • 78649816569 scopus 로고    scopus 로고
    • Nanoscale phase dynamics of the normal tear film
    • S. Khanal, and T.J. Millar Nanoscale phase dynamics of the normal tear film Nanomedicine 6 2010 707 713
    • (2010) Nanomedicine , vol.6 , pp. 707-713
    • Khanal, S.1    Millar, T.J.2
  • 20
    • 0021173258 scopus 로고
    • Peroxisomes in sebaceous glands. IV. Aggregates of tubular peroxisomes in the mouse Meibomian gland
    • K. Gorgas, and A. Volkl Peroxisomes in sebaceous glands. IV. Aggregates of tubular peroxisomes in the mouse Meibomian gland Histochem J 16 1984 1079 1098 (Pubitemid 14046596)
    • (1984) Histochemical Journal , vol.16 , Issue.10 , pp. 1079-1098
    • Gorgas, K.1    Volkl, A.2
  • 21
    • 70849130750 scopus 로고    scopus 로고
    • Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum
    • I.A. Butovich, J.C. Wojtowicz, and M. Molai Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum J Lipid Res 50 2009 2471 2485
    • (2009) J Lipid Res , vol.50 , pp. 2471-2485
    • Butovich, I.A.1    Wojtowicz, J.C.2    Molai, M.3
  • 24
    • 3943066988 scopus 로고    scopus 로고
    • Feasibility of rapid quantitation of stratum corneum lipid content by Fourier transform infrared spectrometry
    • J.C. Tsai, Y.L. Lo, C.Y. Lin, H.M. Sheu, and J.C. Lin Feasibility of rapid quantitation of stratum corneum lipid content by Fourier transform infrared spectrometry Spectrosc Int J 18 2004 423 431
    • (2004) Spectrosc Int J , vol.18 , pp. 423-431
    • Tsai, J.C.1    Lo, Y.L.2    Lin, C.Y.3    Sheu, H.M.4    Lin, J.C.5
  • 25
    • 70449259525 scopus 로고
    • Examination of lipids in human sebum by disk chromatography
    • J. Horacek, and M. Cernikova Examination of lipids in human sebum by disk chromatography Biochem J 71 1959 417 419
    • (1959) Biochem J , vol.71 , pp. 417-419
    • Horacek, J.1    Cernikova, M.2
  • 26
    • 77954310059 scopus 로고    scopus 로고
    • Fatty acid composition of cholesteryl esters of human Meibomian gland secretions
    • I.A. Butovich Fatty acid composition of cholesteryl esters of human Meibomian gland secretions Steroids 75 2010 726 733
    • (2010) Steroids , vol.75 , pp. 726-733
    • Butovich, I.A.1
  • 27
    • 34548244536 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometric analysis of lipids present in human meibomian gland secretions
    • DOI 10.1007/s11745-007-3080-2
    • I.A. Butovich, E. Uchiyama, M.A. Di Pascuale, and J.P. McCulley Liquid chromatography-mass spectrometric analysis of lipids present in human Meibomian gland secretions Lipids 42 2007 765 776 (Pubitemid 47328762)
    • (2007) Lipids , vol.42 , Issue.8 , pp. 765-776
    • Butovich, I.A.1    Uchiyama, E.2    Di Pascuale, M.A.3    McCulley, J.P.4
  • 28
    • 0015091989 scopus 로고
    • Condensation of ninhydrin with aldehydes and primary amines to yield highly fluorescent ternary products. II. Application to the detection and assay of peptides, amino acids, amines, and amino sugars
    • K. Samejima, W. Dairman, J. Stone, and S. Udenfriend Condensation of ninhydrin with aldehydes and primary amines to yield highly fluorescent ternary products. II. Application to the detection and assay of peptides, amino acids, amines, and amino sugars Anal Biochem 42 1971 237 247
    • (1971) Anal Biochem , vol.42 , pp. 237-247
    • Samejima, K.1    Dairman, W.2    Stone, J.3    Udenfriend, S.4
  • 29
    • 0015091786 scopus 로고
    • Condensation of ninhydrin with aldehydes and primary amines to yield highly fluorescent ternary products. I. Studies on the mechanism of the reaction and some characteristics of the condensation product
    • K. Samejima, W. Dairman, and S. Udenfriend Condensation of ninhydrin with aldehydes and primary amines to yield highly fluorescent ternary products. I. Studies on the mechanism of the reaction and some characteristics of the condensation product Anal Biochem 42 1971 222 236
    • (1971) Anal Biochem , vol.42 , pp. 222-236
    • Samejima, K.1    Dairman, W.2    Udenfriend, S.3
  • 30
    • 51249194732 scopus 로고
    • Skin Lipids. II. Lipid Class composition of samples from various species and anatomical sites
    • N. Nicolaides Skin Lipids. II. Lipid Class composition of samples from various species and anatomical sites J Am Oil Chem Soc 42 1965 691 702
    • (1965) J Am Oil Chem Soc , vol.42 , pp. 691-702
    • Nicolaides, N.1
  • 31
    • 0014487520 scopus 로고
    • The structure of alkane diols of diesters in vernix caseosa lipids
    • H.C. Fu, and N. Nicolaides The structure of alkane diols of diesters in vernix caseosa lipids Lipids 4 1969 170 175
    • (1969) Lipids , vol.4 , pp. 170-175
    • Fu, H.C.1    Nicolaides, N.2
  • 32
    • 0014739615 scopus 로고
    • Fatty acids of the alkane diol diesters of vernix caseosa
    • M.N. Ansari, H.C. Fu, and N. Nicolaides Fatty acids of the alkane diol diesters of vernix caseosa Lipids 5 1970 279 282
    • (1970) Lipids , vol.5 , pp. 279-282
    • Ansari, M.N.1    Fu, H.C.2    Nicolaides, N.3
  • 33
    • 0021825098 scopus 로고
    • The di- and triesters of the lipids of steer and human meibomian glands
    • DOI 10.1007/BF02534237
    • N. Nicolaides, and E.C. Santos The di- and triesters of the lipids of steer and human Meibomian glands Lipids 20 1985 454 467 (Pubitemid 15007700)
    • (1985) Lipids , vol.20 , Issue.7 , pp. 454-467
    • Nicolaides, N.1    Santos, E.C.2
  • 36
    • 0021879742 scopus 로고
    • Biosynthesis of lipids by bovine meibomian glands
    • DOI 10.1007/BF02534238
    • P.E. Kolattukudy, L.M. Rogers, and N. Nicolaides Biosynthesis of lipids by bovine Meibomian glands Lipids 20 1985 468 474 (Pubitemid 15007701)
    • (1985) Lipids , vol.20 , Issue.7 , pp. 468-474
    • Kolattukudy, P.E.1    Rogers, L.M.2    Nicolaides, N.3
  • 37
    • 0021681137 scopus 로고
    • The occurrence of long chain α,ω-diols in the lipids of steer and human meibomian glands
    • DOI 10.1007/BF02534741
    • N. Nicolaides, E.C. Santos, K. Papadakis, E.C. Ruth, and L. Muller The occurrence of long chain alpha, omega-diols in the lipids of steer and human Meibomian glands Lipids 19 1984 990 993 (Pubitemid 15196506)
    • (1984) Lipids , vol.19 , Issue.12 , pp. 990-993
    • Nicolaides, N.1    Santos, E.C.2    Papadakis, K.3
  • 38
    • 0021414474 scopus 로고
    • Double-bond patterns of fatty acids and alcohols in steer and human Meibomian gland lipids
    • N. Nicolaides, E.C. Santos, and K. Papadakis Double-bond patterns of fatty acids and alcohols in steer and human Meibomian gland lipids Lipids 19 1984 264 277
    • (1984) Lipids , vol.19 , pp. 264-277
    • Nicolaides, N.1    Santos, E.C.2    Papadakis, K.3
  • 39
    • 0020422526 scopus 로고
    • Unusual fatty acids in the lipid of steer and human meibomian gland excreta
    • N. Nicolaides, and E.C. Ruth Unusual fatty acids in the lipids of steer and human Meibomian gland excreta Curr Eye Res 2 1982 93 98 (Pubitemid 13208644)
    • (1982) Current Eye Research , vol.2 , Issue.2 , pp. 93-98
    • Nicolaides, N.1    Ruth, E.C.2
  • 40
    • 0018521117 scopus 로고
    • Application of combined liquid chromatography/mass spectrometry (LC/MS): Analysis of petroporphyrins and meibomian gland waxes
    • W.H. McFadden, D.C. Bradford, G. Eglinton, S.K. Hajlbrahim, and N. Nicolaides Application of combined liquid chromatography/mass spectrometry (LC/MS): analysis of petroporphyrins and Meibomian gland waxes J Chromatogr Sci 17 1979 518 522 (Pubitemid 10412544)
    • (1979) Journal of Chromatographic Science , vol.17 , Issue.9 , pp. 518-522
    • McFadden, W.H.1    Bradford, D.C.2    Eglinton, G.3    Hajlbrahim, S.K.4    Nicolaides, N.5
  • 41
    • 0014168498 scopus 로고
    • Seborrhoeic blepharo-kerato-conjunctivitis
    • C.G. Keith Seborrhoeic blepharo-kerato-conjunctivitis Trans Ophthalmol Soc UK 87 1967 85 103
    • (1967) Trans Ophthalmol Soc UK , vol.87 , pp. 85-103
    • Keith, C.G.1
  • 42
    • 0015801689 scopus 로고
    • The Meibomian secretion
    • J.S. Andrews The Meibomian secretion Int Ophthalmol Clin 13 1973 23 28
    • (1973) Int Ophthalmol Clin , vol.13 , pp. 23-28
    • Andrews, J.S.1
  • 43
    • 70350356367 scopus 로고    scopus 로고
    • The Meibomian puzzle: Combining pieces together
    • I.A. Butovich The Meibomian puzzle: combining pieces together Prog Retin Eye Res 28 2009 483 498
    • (2009) Prog Retin Eye Res , vol.28 , pp. 483-498
    • Butovich, I.A.1
  • 44
    • 0015896834 scopus 로고
    • Meibomian gland secretion in the red eyes of rosacea
    • C.C. Cory, W. Hinks, J.L. Burton, and S. Shuster Meibomian gland secretion in the red eyes of rosacea Br J Dermatol 89 1973 25 27
    • (1973) Br J Dermatol , vol.89 , pp. 25-27
    • Cory, C.C.1    Hinks, W.2    Burton, J.L.3    Shuster, S.4
  • 45
    • 0018093663 scopus 로고
    • Individual variations in human meibomian lipid composition
    • J.M. Tiffany Individual variations in human Meibomian lipid composition Exp Eye Res 27 1978 289 300 (Pubitemid 9016661)
    • (1978) Experimental Eye Research , vol.27 , Issue.3 , pp. 289-300
    • Tiffany, J.M.1
  • 47
    • 0024406335 scopus 로고
    • Meibomian gland dysfunction. I. Keratin protein expression in normal human and rabbit meibomian glands
    • J.V. Jester, N. Nicolaides, and R.E. Smith Meibomian gland dysfunction. I. Keratin protein expression in normal human and rabbit Meibomian glands Invest Ophthalmol Vis Sci 30 1989 927 935 (Pubitemid 19140186)
    • (1989) Investigative Ophthalmology and Visual Science , vol.30 , Issue.5 , pp. 927-935
    • Jester, J.V.1    Nicolaides, N.2    Smith, R.E.3
  • 48
    • 0022347721 scopus 로고
    • In vivo transillumination biomicroscopy and photography of meibomian gland dysfunction: A clinical study
    • J.B. Robin, J.V. Jester, J. Nobe, N. Nicolaides, and R.E. Smith In vivo transillumination biomicroscopy and photography of Meibomian gland dysfunction. A clinical study Ophthalmology 92 1985 1423 1426 (Pubitemid 16193375)
    • (1985) Ophthalmology , vol.92 , Issue.10 , pp. 1423-1426
    • Robin, J.B.1    Jester Nobe, J.V.J.2
  • 49
    • 0022647115 scopus 로고
    • Analysis of the free fatty acid component of meibomian secretions in chronic blepharitis
    • J.M. Dougherty, and J.P. McCulley Analysis of the free fatty acid component of Meibomian secretions in chronic blepharitis Invest Ophthalmol Vis Sci 27 1986 52 56 (Pubitemid 16127671)
    • (1986) Investigative Ophthalmology and Visual Science , vol.27 , Issue.1 , pp. 52-56
    • Dougherty, J.M.1    McCulley, J.P.2
  • 50
    • 0023112174 scopus 로고
    • Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the meibomian glands of the rat and a comparison with human meibomian lipids
    • D.J. Harvey, J.M. Tiffany, J.M. Duerden, K.S. Pandher, and L.S. Mengher Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the Meibomian glands of the rat and a comparison with human Meibomian lipids J Chromatogr 414 1987 253 263 (Pubitemid 17041677)
    • (1987) Journal of Chromatography - Biomedical Applications , vol.414 , Issue.2 , pp. 253-263
    • Harvey, D.J.1    Tiffany, J.M.2    Duerden, J.M.3
  • 52
    • 0026161143 scopus 로고
    • The role of wax and sterol ester fatty acids in chronic blepharitis
    • J.M. Dougherty, J.K. Osgood, and J.P. McCulley The role of wax and sterol ester fatty acids in chronic blepharitis Invest Ophthalmol Vis Sci 32 1991 1932 1937
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 1932-1937
    • Dougherty, J.M.1    Osgood, J.K.2    McCulley, J.P.3
  • 53
    • 0025951244 scopus 로고
    • The role of cholesterol in chronic blepharitis
    • W.E. Shine, and J.P. McCulley The role of cholesterol in chronic blepharitis Invest Ophthalmol Vis Sci 32 1991 2272 2280
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 2272-2280
    • Shine, W.E.1    McCulley, J.P.2
  • 55
    • 0029890759 scopus 로고    scopus 로고
    • Meibomian gland triglyceride fatty acid differences in chronic blepharitis patients
    • DOI 10.1097/00003226-199607000-00002
    • W.E. Shine, and J.P. McCulley Meibomian gland triglyceride fatty acid differences in chronic blepharitis patients Cornea 15 1996 340 346 (Pubitemid 26189972)
    • (1996) Cornea , vol.15 , Issue.4 , pp. 340-346
    • Shine, W.E.1    McCulley, J.P.2
  • 57
    • 77956141169 scopus 로고    scopus 로고
    • Confirmation of changes in human meibum lipid infrared spectra with age using principal component analysis
    • D. Borchman, G.N. Foulks, and M.C. Yappert Confirmation of changes in human meibum lipid infrared spectra with age using principal component analysis Curr Eye Res 35 2010 778 786
    • (2010) Curr Eye Res , vol.35 , pp. 778-786
    • Borchman, D.1    Foulks, G.N.2    Yappert, M.C.3
  • 58
    • 79952100523 scopus 로고    scopus 로고
    • Shotgun lipidomic analysis of human Meibomian gland secretions with electrospray ionization tandem mass spectrometry
    • J. Chen, K.B. Green-Church, and K.K. Nichols Shotgun lipidomic analysis of human Meibomian gland secretions with electrospray ionization tandem mass spectrometry Invest Ophthalmol Vis Sci 51 2010 6220 6231
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 6220-6231
    • Chen, J.1    Green-Church, K.B.2    Nichols, K.K.3
  • 59
    • 73949102082 scopus 로고    scopus 로고
    • Meibomian glands. Part II: Physiology, characteristics, distribution and function of Meibomian oil
    • E. Knop, N. Knop, and F. Schirra Meibomian glands. Part II: physiology, characteristics, distribution and function of Meibomian oil Ophthalmologe 106 2009 884 892
    • (2009) Ophthalmologe , vol.106 , pp. 884-892
    • Knop, E.1    Knop, N.2    Schirra, F.3
  • 61
    • 70349658842 scopus 로고    scopus 로고
    • Historical brief on composition of human meibum lipids
    • J.C. Wojtowicz, I.A. Butovich, and J.P. McCulley Historical brief on composition of human meibum lipids Ocul Surf 7 2009 145 153
    • (2009) Ocul Surf , vol.7 , pp. 145-153
    • Wojtowicz, J.C.1    Butovich, I.A.2    McCulley, J.P.3
  • 62
    • 33748616243 scopus 로고    scopus 로고
    • Influence of aging on the polar and neutral lipid profiles in human meibomian gland secretions
    • DOI 10.1001/archopht.124.9.1286
    • B.D. Sullivan, J.E. Evans, M.R. Dana, and D.A. Sullivan Influence of aging on the polar and neutral lipid profiles in human Meibomian gland secretions Arch Ophthalmol 124 2006 1286 1292 (Pubitemid 44379863)
    • (2006) Archives of Ophthalmology , vol.124 , Issue.9 , pp. 1286-1292
    • Sullivan, B.D.1    Evans, J.E.2    Dana, M.R.3    Sullivan, D.A.4
  • 63
    • 7444264036 scopus 로고    scopus 로고
    • Meibomianitis: Polar lipid abnormalities
    • DOI 10.1097/01.ico.0000133995.99520.1f
    • W.E. Shine, and J.P. McCulley Meibomianitis: polar lipid abnormalities Cornea 23 2004 781 783 (Pubitemid 39447307)
    • (2004) Cornea , vol.23 , Issue.8 , pp. 781-783
    • Shine, W.E.1    McCulley, J.P.2
  • 65
    • 0037758009 scopus 로고    scopus 로고
    • Polar lipids in human meibomian gland secretions
    • DOI 10.1076/ceyr.26.2.89.14515
    • W.E. Shine, and J.P. McCulley Polar lipids in human Meibomian gland secretions Curr Eye Res 26 2003 89 94 (Pubitemid 36776115)
    • (2003) Current Eye Research , vol.26 , Issue.2 , pp. 89-94
    • Shine, W.E.1    McCulley, J.P.2
  • 66
    • 0038340367 scopus 로고    scopus 로고
    • Eyelid disorders: The Meibomian gland, blepharitis, and contact lenses
    • J.P. McCulley, and W.E. Shine Eyelid disorders: the Meibomian gland, blepharitis, and contact lenses Eye Contact Lens 29 2003 S93 S95 [discussion S115-8, S92-4]
    • (2003) Eye Contact Lens , vol.29
    • McCulley, J.P.1    Shine, W.E.2
  • 69
    • 34948898136 scopus 로고    scopus 로고
    • Lipids of human meibum: Mass-spectrometric analysis and structural elucidation
    • DOI 10.1194/jlr.M700237-JLR200
    • I.A. Butovich, E. Uchiyama, and J.P. McCulley Lipids of human meibum: mass-spectrometric analysis and structural elucidation J Lipid Res 48 2007 2220 2235 (Pubitemid 47529564)
    • (2007) Journal of Lipid Research , vol.48 , Issue.10 , pp. 2220-2235
    • Butovich, I.A.1    Uchiyama, E.2    McCulley, J.P.3
  • 70
    • 0032987673 scopus 로고    scopus 로고
    • Components responsible for the surface tension of human tears
    • DOI 10.1076/ceyr.19.1.4.5341
    • B. Nagyova, and J.M. Tiffany Components responsible for the surface tension of human tears Curr Eye Res 19 1999 4 11 (Pubitemid 29308823)
    • (1999) Current Eye Research , vol.19 , Issue.1 , pp. 4-11
    • Nagyova, B.1    Tiffany, J.M.2
  • 71
    • 33646783664 scopus 로고    scopus 로고
    • Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality
    • W.E. Shine, and J.P. McCulley Keratoconjunctivitis sicca associated with Meibomian secretion polar lipid abnormality Arch Ophthalmol 116 1998 849 852 (Pubitemid 28554773)
    • (1998) Archives of Ophthalmology , vol.116 , Issue.7 , pp. 849-852
    • Shine, W.E.1    McCulley, J.P.2
  • 72
    • 0030698236 scopus 로고    scopus 로고
    • A compositional based model for the tear film lipid layer
    • J.P. McCulley, and W. Shine A compositional based model for the tear film lipid layer Trans Am Ophthalmol Soc 95 1997 79 88 [discussion-93]
    • (1997) Trans Am Ophthalmol Soc , vol.95 , pp. 79-88
    • McCulley, J.P.1    Shine, W.2
  • 73
    • 79955933622 scopus 로고    scopus 로고
    • On the presence and role of polar lipids in meibum
    • I.A. Butovich On the presence and role of polar lipids in meibum Invest Ophthalmol Vis Sci 51 2010 6908 6910 [author reply 10-11]
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 6908-6910
    • Butovich, I.A.1
  • 74
    • 0015877652 scopus 로고
    • Formation and rupture of the tear film
    • F.J. Holly Formation and rupture of the tear film Exp Eye Res 15 1973 515 525
    • (1973) Exp Eye Res , vol.15 , pp. 515-525
    • Holly, F.J.1
  • 75
    • 0015796368 scopus 로고
    • Formation and stability of the tear film
    • F.J. Holly Formation and stability of the tear film Int Ophthalmol Clin 13 1973 73 96
    • (1973) Int Ophthalmol Clin , vol.13 , pp. 73-96
    • Holly, F.J.1
  • 77
    • 0033989462 scopus 로고    scopus 로고
    • Association of meibum oleic acid with meibomian seborrhea
    • DOI 10.1097/00003226-200001000-00014
    • W.E. Shine, and J.P. McCulley Association of meibum oleic acid with Meibomian seborrhea Cornea 19 2000 72 74 (Pubitemid 30007748)
    • (2000) Cornea , vol.19 , Issue.1 , pp. 72-74
    • Shine, W.E.1    McCulley, J.P.2
  • 78
    • 77955857267 scopus 로고    scopus 로고
    • Culture, immortalization, and characterization of human meibomian gland epithelial cells
    • S. Liu, M.P. Hatton, P. Khandelwal, and D.A. Sullivan Culture, immortalization, and characterization of human meibomian gland epithelial cells Invest Ophthalmol Vis Sci 51 2010 3993 4005
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3993-4005
    • Liu, S.1    Hatton, M.P.2    Khandelwal, P.3    Sullivan, D.A.4
  • 79
    • 33745051855 scopus 로고    scopus 로고
    • Identification of steroidogenic enzyme mRNAs in the human lacrimal gland, meibomian gland, cornea, and conjunctiva
    • DOI 10.1097/01.ico.0000183664.80004.44, PII 0000322620060500000012
    • F. Schirra, T. Suzuki, D.P. Dickinson, D.J. Townsend, I.K. Gipson, and D.A. Sullivan Identification of steroidogenic enzyme mRNAs in the human lacrimal gland, Meibomian gland, cornea, and conjunctiva Cornea 25 2006 438 442 (Pubitemid 44620129)
    • (2006) Cornea , vol.25 , Issue.4 , pp. 438-442
    • Schirra, F.1    Suzuki, T.2    Dickinson, D.P.3    Townsend, D.J.4    Gipson, I.K.5    Sullivan, D.A.6
  • 80
    • 0042344725 scopus 로고    scopus 로고
    • Is complete androgen insensitivity syndrome associated with alterations in the meibomian gland and ocular surface?
    • DOI 10.1097/00003226-200308000-00006
    • J.M. Cermak, K.L. Krenzer, R.M. Sullivan, M.R. Dana, and D.A. Sullivan Is complete androgen insensitivity syndrome associated with alterations in the Meibomian gland and ocular surface? Cornea 22 2003 516 521 (Pubitemid 36909729)
    • (2003) Cornea , vol.22 , Issue.6 , pp. 516-521
    • Cermak, J.M.1    Krenzer, K.L.2    Sullivan, R.M.3    Dana, M.R.4    Sullivan, D.A.5
  • 84
    • 0034488868 scopus 로고    scopus 로고
    • Impact of antiandrogen treatment on the fatty acid profile of neutral lipids in human meibomian gland secretions
    • DOI 10.1210/jc.85.12.4866
    • B.D. Sullivan, J.E. Evans, K.L. Krenzer, M. Reza Dana, and D.A. Sullivan Impact of antiandrogen treatment on the fatty acid profile of neutral lipids in human Meibomian gland secretions J Clin Endocrinol Metab 85 2000 4866 4873 (Pubitemid 32157679)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.12 , pp. 4866-4873
    • Sullivan, B.D.1    Evans, J.E.2    Krenzer, K.L.3    Dana, M.R.4    Sullivan, D.A.5
  • 85
    • 0034035187 scopus 로고    scopus 로고
    • Identification of androgen, estrogen and progesterone receptor mRNAs in the eye
    • DOI 10.1034/j.1600-0420.2000.078002146.x
    • L.A. Wickham, J. Gao, I. Toda, E.M. Rocha, M. Ono, and D.A. Sullivan Identification of androgen, estrogen and progesterone receptor mRNAs in the eye Acta Ophthalmol Scand 78 2000 146 153 (Pubitemid 30201420)
    • (2000) Acta Ophthalmologica Scandinavica , vol.78 , Issue.2 , pp. 146-153
    • Wickham, L.A.1    Gao, J.2    Toda, I.3    Rocha, E.M.4    Ono, M.5    Sullivan, D.A.6
  • 90
    • 33744927407 scopus 로고    scopus 로고
    • Androgen regulation of lipogenic pathways in the mouse meibomian gland
    • DOI 10.1016/j.exer.2005.11.026, PII S0014483506001308
    • F. Schirra, S.M. Richards, M. Liu, T. Suzuki, H. Yamagami, and D.A. Sullivan Androgen regulation of lipogenic pathways in the mouse Meibomian gland Exp Eye Res 83 2006 291 296 (Pubitemid 43850944)
    • (2006) Experimental Eye Research , vol.83 , Issue.2 , pp. 291-296
    • Schirra, F.1    Richards, S.M.2    Liu, M.3    Suzuki, T.4    Yamagami, H.5    Sullivan, D.A.6
  • 91
    • 34249016656 scopus 로고    scopus 로고
    • Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland
    • DOI 10.1080/02713680701316674, PII 778880730
    • F. Schirra, S.M. Richards, and D.A. Sullivan Androgen influence on cholesterogenic enzyme mRNA levels in the mouse Meibomian gland Curr Eye Res 32 2007 393 398 (Pubitemid 46789432)
    • (2007) Current Eye Research , vol.32 , Issue.5 , pp. 393-398
    • Schirra, F.1    Richards, S.M.2    Sullivan, D.A.3
  • 93
    • 0028365348 scopus 로고
    • High-performance liquid chromatographic analysis of phospholipids from different sources with combined fluorescence and ultraviolet detection
    • DOI 10.1006/abio.1994.1315
    • W. Bernhard, M. Linck, H. Creutzburg, A.D. Postle, A. Arning, and I. Martin-Carrera High-performance liquid chromatographic analysis of phospholipids from different sources with combined fluorescence and ultraviolet detection Anal Biochem 220 1994 172 180 (Pubitemid 24227235)
    • (1994) Analytical Biochemistry , vol.220 , Issue.1 , pp. 172-180
    • Bernhard, W.1    Linck, M.2    Creutzburg, H.3    Postle, A.D.4    Arning, A.5    Martin-Carrera, I.6    Sewing, K.-F.7
  • 97
    • 53149111576 scopus 로고    scopus 로고
    • On the lipid composition of human meibum and tears: Comparative analysis of nonpolar lipids
    • I.A. Butovich On the lipid composition of human meibum and tears: comparative analysis of nonpolar lipids Invest Ophthalmol Vis Sci 49 2008 3779 3789
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3779-3789
    • Butovich, I.A.1
  • 98
    • 38349137382 scopus 로고    scopus 로고
    • Differences in Meibomian fatty acid composition in patients with Meibomian gland dysfunction and aqueous-deficient dry eye
    • C. Joffre, M. Souchier, S. Gregoire, S. Viau, L. Bretillon, and N. Acar Differences in Meibomian fatty acid composition in patients with Meibomian gland dysfunction and aqueous-deficient dry eye Br J Ophthalmol 92 2008 116 119
    • (2008) Br J Ophthalmol , vol.92 , pp. 116-119
    • Joffre, C.1    Souchier, M.2    Gregoire, S.3    Viau, S.4    Bretillon, L.5    Acar, N.6
  • 100
    • 34948842499 scopus 로고    scopus 로고
    • Temperature-induced conformational changes in human tear lipids hydrocarbon chains
    • DOI 10.1002/bip.20798
    • D. Borchman, G.N. Foulks, M.C. Yappert, and D.V. Ho Temperature-induced conformational changes in human tearlipids hydrocarbon chains Biopolymers 87 2007 124 133 (Pubitemid 47518363)
    • (2007) Biopolymers , vol.87 , Issue.2-3 , pp. 124-133
    • Borchman, D.1    Foulks, G.N.2    Yappert, M.C.3    Ho, D.V.4
  • 102
    • 0019569437 scopus 로고
    • Separation of wax esters from steryl esters by chromatography on magnesium hydroxide
    • M.E. Stewart, and D.T. Downing Separation of wax esters from steryl esters by chromatography on magnesium hydroxide Lipids 16 1981 355 359
    • (1981) Lipids , vol.16 , pp. 355-359
    • Stewart, M.E.1    Downing, D.T.2
  • 103
    • 42949084908 scopus 로고    scopus 로고
    • Quantitative evaluation of sebum lipid components with nuclear magnetic resonance
    • L.C. Robosky, K. Wade, D. Woolson, J.D. Baker, M.L. Manning, and D.A. Gage Quantitative evaluation of sebum lipid components with nuclear magnetic resonance J Lipid Res 49 2008 686 692
    • (2008) J Lipid Res , vol.49 , pp. 686-692
    • Robosky, L.C.1    Wade, K.2    Woolson, D.3    Baker, J.D.4    Manning, M.L.5    Gage, D.A.6
  • 104
    • 12944265405 scopus 로고    scopus 로고
    • 1H NMR: Development and potential of a method for natural products analysis
    • DOI 10.1021/np0497301
    • 1H NMR: development and potential of a method for natural products analysis J Nat Prod 68 2005 133 149 (Pubitemid 40175949)
    • (2005) Journal of Natural Products , vol.68 , Issue.1 , pp. 133-149
    • Pauli, G.F.1    Jaki, B.U.2    Lankin, D.C.3
  • 105
    • 0033832634 scopus 로고    scopus 로고
    • Applications of hyphenated LC-MS techniques in pharmaceutical analysis
    • J. Ermer, and M. Vogel Applications of hyphenated LC-MS techniques in pharmaceutical analysis Biomed Chromatogr 14 2000 373 383
    • (2000) Biomed Chromatogr , vol.14 , pp. 373-383
    • Ermer, J.1    Vogel, M.2
  • 109
    • 47949123685 scopus 로고    scopus 로고
    • Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma
    • P.M. Lam, T.H. Marczylo, M. El-Talatini, M. Finney, V. Nallendran, and A.H. Taylor Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma Anal Biochem 380 2008 195 201
    • (2008) Anal Biochem , vol.380 , pp. 195-201
    • Lam, P.M.1    Marczylo, T.H.2    El-Talatini, M.3    Finney, M.4    Nallendran, V.5    Taylor, A.H.6
  • 111
    • 66849122694 scopus 로고    scopus 로고
    • Shotgun lipidomics of neutral lipids as an enabling technology for elucidation of lipid-related diseases
    • R.W. Gross, and X. Han Shotgun lipidomics of neutral lipids as an enabling technology for elucidation of lipid-related diseases Am J Physiol Endocrinol Metab 297 2009 E297 E303
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Gross, R.W.1    Han, X.2
  • 112
    • 17244377704 scopus 로고    scopus 로고
    • Shotgun lipidomics: Multidimensional MS analysis of cellular lipidomes
    • DOI 10.1586/14789450.2.2.253
    • X. Han, and R.W. Gross Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes Expert Rev Proteomics 2 2005 253 264 (Pubitemid 40529863)
    • (2005) Expert Review of Proteomics , vol.2 , Issue.2 , pp. 253-264
    • Han, X.1    Gross, R.W.2
  • 113
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
    • DOI 10.1002/mas.20023
    • X. Han, and R.W. Gross Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples Mass Spectrom Rev 24 2005 367 412 (Pubitemid 40665798)
    • (2005) Mass Spectrometry Reviews , vol.24 , Issue.3 , pp. 367-412
    • Han, X.1    Gross, R.W.2
  • 114
    • 33847206460 scopus 로고    scopus 로고
    • Distinguishing between cis/trans isomers of monounsaturated fatty acids by FAB MS
    • H. Ji, V.G. Voinov, M.L. Deinzer, and D.F. Barofsky Distinguishing between cis/trans isomers of monounsaturated fatty acids by FAB MS Anal Chem 79 2007 1519 1522
    • (2007) Anal Chem , vol.79 , pp. 1519-1522
    • Ji, H.1    Voinov, V.G.2    Deinzer, M.L.3    Barofsky, D.F.4
  • 115
    • 0032536124 scopus 로고    scopus 로고
    • Silver ion high-performance liquid chromatography of isomeric cis- and trans-octadecenoic acids. Effect of the ester moiety and mobile phase composition
    • DOI 10.1016/S0021-9673(97)00907-2, PII S0021967397009072
    • S. Momchilova, B. Nikolova-Damyanova, and W.W. Christie Silver ion high-performance liquid chromatography of isomeric cis- and trans-octadecenoic acids: effect of the ester moiety and mobile phase composition J Chromatogr A 793 1998 275 282 (Pubitemid 28044253)
    • (1998) Journal of Chromatography A , vol.793 , Issue.2 , pp. 275-282
    • Momchilova, Sv.1    Nikolova-Damyanova, B.2    Christie, W.W.3
  • 116
    • 0035820322 scopus 로고    scopus 로고
    • Enzyme-catalyzed and enzyme-triggered pathways in dioxygenation of 1-monolinoleoyl-rac-glycerol by potato tuber lipoxygenase
    • DOI 10.1016/S0167-4838(01)00162-5, PII S0167483801001625
    • I.A. Butovich, and C.C. Reddy Enzyme-catalyzed and enzyme-triggered pathways in dioxygenation of 1-monolinoleoyl-rac-glycerol by potato tuber lipoxygenase Biochim Biophys Acta 1546 2001 379 398 (Pubitemid 32280833)
    • (2001) Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology , vol.1546 , Issue.2 , pp. 379-398
    • Butovich, I.A.1    Reddy C.Channa2
  • 117
    • 0019330094 scopus 로고
    • Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase
    • M. Hamberg, and B. Samuelsson Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase Biochim Biophys Acta 617 1980 545 547
    • (1980) Biochim Biophys Acta , vol.617 , pp. 545-547
    • Hamberg, M.1    Samuelsson, B.2
  • 118
    • 0015135670 scopus 로고
    • Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid
    • M. Hamberg Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid Anal Biochem 43 1971 515 526
    • (1971) Anal Biochem , vol.43 , pp. 515-526
    • Hamberg, M.1
  • 119
    • 79952467442 scopus 로고    scopus 로고
    • On the presence of (o-acyl)-omega-hydroxy fatty acids and of their esters in human meibomian gland secretions
    • I.A. Butovich On the presence of (o-acyl)-omega-hydroxy fatty acids and of their esters in human meibomian gland secretions Invest Ophthalmol Vis Sci 52 2011 639 641
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 639-641
    • Butovich, I.A.1
  • 120
    • 0014439936 scopus 로고
    • Melting points of synthetic wax esters
    • B.T. Iyengar, and H. Schlenk Melting points of synthetic wax esters Lipids 4 1969 28 30
    • (1969) Lipids , vol.4 , pp. 28-30
    • Iyengar, B.T.1    Schlenk, H.2
  • 121
    • 0009370455 scopus 로고    scopus 로고
    • Chemical and physical analyses of wax ester properties
    • S. Patel, D.R. Nelson, and A.G. Gibbs Chemical and physical analyses of wax ester properties J Insect Sci 1 2001 4
    • (2001) J Insect Sci , vol.1 , pp. 4
    • Patel, S.1    Nelson, D.R.2    Gibbs, A.G.3
  • 123
    • 79951771809 scopus 로고    scopus 로고
    • Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye
    • J.C. Wojtowicz, I. Butovich, E. Uchiyama, J. Aronowicz, S. Agee, and J.P. McCulley Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye Cornea 30 2011 308 314
    • (2011) Cornea , vol.30 , pp. 308-314
    • Wojtowicz, J.C.1    Butovich, I.2    Uchiyama, E.3    Aronowicz, J.4    Agee, S.5    McCulley, J.P.6
  • 124
    • 33847309844 scopus 로고    scopus 로고
    • Identification of very long chain unsaturated fatty acids from Ximenia oil by atmospheric pressure chemical ionization liquid chromatography-mass spectroscopy
    • DOI 10.1016/j.phytochem.2006.11.034, PII S0031942206007436
    • T. Rezanka, and K. Sigler Identification of very long chain unsaturated fatty acids from Ximenia oil by atmospheric pressure chemical ionization liquid chromatography-mass spectroscopy Phytochemistry 68 2007 925 934 (Pubitemid 46330440)
    • (2007) Phytochemistry , vol.68 , Issue.6 , pp. 925-934
    • Rezanka, T.1    Sigler, K.2
  • 125
    • 0037375069 scopus 로고    scopus 로고
    • Minocycline effect on meibomian gland lipids in meibomianitis patients
    • DOI 10.1016/S0014-4835(03)00005-8
    • W.E. Shine, J.P. McCulley, and A.G. Pandya Minocycline effect on Meibomian gland lipids in meibomianitis patients Exp Eye Res 76 2003 417 420 (Pubitemid 36299053)
    • (2003) Experimental Eye Research , vol.76 , Issue.4 , pp. 417-420
    • Shine, W.E.1    McCulley, J.P.2    Pandya, A.G.3
  • 126
    • 0025933484 scopus 로고
    • The role of tetracycline in chronic blepharitis. Inhibition of lipase production in staphylococci
    • J.M. Dougherty, J.P. McCulley, R.E. Silvany, and D.R. Meyer The role of tetracycline in chronic blepharitis. Inhibition of lipase production in staphylococci Invest Ophthalmol Vis Sci 32 1991 2970 2975
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 2970-2975
    • Dougherty, J.M.1    McCulley, J.P.2    Silvany, R.E.3    Meyer, D.R.4
  • 127
    • 0019922915 scopus 로고
    • Classification of chronic blepharitis
    • J.P. McCulley, J.M. Dougherty, and D.G. Deneau Classification of chronic blepharitis Ophthalmology 89 1982 1173 1180 (Pubitemid 12003236)
    • (1982) Ophthalmology , vol.89 , Issue.10 , pp. 1173-1180
    • McCulley, J.P.1    Dougherty, J.M.2    Deneau, D.G.3
  • 128
    • 0031706109 scopus 로고    scopus 로고
    • Identification and analysis of polymer additives using packed-column supercritical fluid chromatography with APCI mass spectrometric detection
    • DOI 10.1039/a803922d
    • M.J. Carrott, D.C. Jones, and G. Davidson Identification and analysis of polymer additives using packed-column supercritical fluid chromatography with APCI mass spectrometric detection Analyst 123 1998 1827 1833 (Pubitemid 28442366)
    • (1998) Analyst , vol.123 , Issue.9 , pp. 1827-1833
    • Carrott, M.J.1
  • 129
    • 79952101281 scopus 로고    scopus 로고
    • Identification of phospholipids in human meibum by nano-electrospray ionisation tandem mass spectrometry
    • J.T. Saville, Z. Zhao, M.D. Willcox, M.A. Ariyavidana, S.J. Blanksby, and T.W. Mitchell Identification of phospholipids in human meibum by nano-electrospray ionisation tandem mass spectrometry Exp Eye Res 92 2011 238 240
    • (2011) Exp Eye Res , vol.92 , pp. 238-240
    • Saville, J.T.1    Zhao, Z.2    Willcox, M.D.3    Ariyavidana, M.A.4    Blanksby, S.J.5    Mitchell, T.W.6
  • 130
    • 27544513987 scopus 로고    scopus 로고
    • MALDI-TOF MS of phosphorylated lipids in biological fluids using immobilized metal affinity chromatography and a solid ionic crystal matrix
    • DOI 10.1021/ac058000a
    • B.M. Ham, J.T. Jacob, and R.B. Cole MALDI-TOF MS of phosphorylated lipids in biological fluids using immobilized metal affinity chromatography and a solid ionic crystal matrix Anal Chem 77 2005 4439 4447 (Pubitemid 41542263)
    • (2005) Analytical Chemistry , vol.77 , Issue.14 , pp. 4439-4447
    • Ham, B.M.1    Jacob, J.T.2    Cole, R.B.3
  • 131
    • 0014076128 scopus 로고
    • Fractionation of hydrocarbons of human hair lipids by chromatographic and thermal diffusion methods
    • L.L. Gershbein, B.K. Krotoszynski, and E.J. Singh Fractionation of hydrocarbons of human hair lipids by chromatographic and thermal diffusion methods J Chromatogr 27 1967 431 449
    • (1967) J Chromatogr , vol.27 , pp. 431-449
    • Gershbein, L.L.1    Krotoszynski, B.K.2    Singh, E.J.3
  • 132
    • 0016886923 scopus 로고
    • Analysis of fatty acid and alcoholic components of sebaceous lipid types
    • H.J. O'Neill, and L.L. Gershbein Analysis of fatty acid and alcoholic components of sebaceous lipid types J Chromatogr Sci 14 1976 28 36
    • (1976) J Chromatogr Sci , vol.14 , pp. 28-36
    • O'Neill, H.J.1    Gershbein, L.L.2
  • 133
    • 77953490959 scopus 로고    scopus 로고
    • Retinal very long-chain PUFAs: New insights from studies on ELOVL4 protein
    • M.P. Agbaga, M.N. Mandal, and R.E. Anderson Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein J Lipid Res 51 2010 1624 1642
    • (2010) J Lipid Res , vol.51 , pp. 1624-1642
    • Agbaga, M.P.1    Mandal, M.N.2    Anderson, R.E.3
  • 134
    • 79955936484 scopus 로고    scopus 로고
    • Surfactant properties of human Meibomian lipids
    • P. Mudgil, and T.J. Millar Surfactant properties of human Meibomian lipids Invest Ophthalmol Vis Sci 52 2011 1661 1670
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 1661-1670
    • Mudgil, P.1    Millar, T.J.2
  • 137
    • 41049085138 scopus 로고    scopus 로고
    • Adsorption of apo- and holo-tear lipocalin to a bovine Meibomian lipid film
    • P. Mudgil, and T.J. Millar Adsorption of apo- and holo-tear lipocalin to a bovine Meibomian lipid film Exp Eye Res 86 2008 622 628
    • (2008) Exp Eye Res , vol.86 , pp. 622-628
    • Mudgil, P.1    Millar, T.J.2
  • 138
    • 29744459137 scopus 로고    scopus 로고
    • The surface activity of purified ocular mucin at the air-liquid interface and interactions with meibomian lipids
    • DOI 10.1097/01.ico.0000164779.87795.3c
    • T.J. Millar, S.T. Tragoulias, P.J. Anderton, M.S. Ball, F. Miano, and G.R. Dennis The surface activity of purified ocular mucin at the air-liquid interface and interactions with Meibomian lipids Cornea 25 2006 91 100 (Pubitemid 43031156)
    • (2006) Cornea , vol.25 , Issue.1 , pp. 91-100
    • Millar, T.J.1    Tragoulias, S.T.2    Anderton, P.J.3    Ball, M.S.4    Miano, F.5    Dennis, G.R.6    Mudgil, P.7
  • 139
    • 14144256753 scopus 로고    scopus 로고
    • Surface pressure measurements of human tears and individual tear film components indicate that proteins are major contributors to the surface pressure
    • DOI 10.1097/01.ico.0000138837.52694.37
    • S.T. Tragoulias, P.J. Anderton, G.R. Dennis, F. Miano, and T.J. Millar Surface pressure measurements of human tears and individual tear film components indicate that proteins are major contributors to the surface pressure Cornea 24 2005 189 200 (Pubitemid 40283831)
    • (2005) Cornea , vol.24 , Issue.2 , pp. 189-200
    • Tragoulias, S.T.1    Anderton, P.J.2    Dennis, G.R.3    Miano, F.4    Millar, T.J.5
  • 140
    • 0028943948 scopus 로고
    • Morphology of the Meibomian lipid film. Results of Brewster angle microscopy
    • T. Kaercher, D. Honig, D. Mobius, and R. Welt Morphology of the Meibomian lipid film. Results of Brewster angle microscopy Ophthalmologe 92 1995 12 16
    • (1995) Ophthalmologe , vol.92 , pp. 12-16
    • Kaercher, T.1    Honig, D.2    Mobius, D.3    Welt, R.4
  • 141
    • 0027848910 scopus 로고
    • Brewster angle microscopy. A new method of visualizing the spreading of Meibomian lipids
    • T. Kaercher, D. Honig, and D. Mobius Brewster angle microscopy. A new method of visualizing the spreading of Meibomian lipids Int Ophthalmol 17 1993 341 348 (Pubitemid 24134941)
    • (1993) International Ophthalmology , vol.17 , Issue.6 , pp. 341-348
    • Kaercher, T.1    Honig, D.2    Mobius, D.3
  • 142
    • 77951248666 scopus 로고    scopus 로고
    • The interfacial viscoelastic properties and structures of human and animal Meibomian lipids
    • D.L. Leiske, S.R. Raju, H.A. Ketelson, T.J. Millar, and G.G. Fuller The interfacial viscoelastic properties and structures of human and animal Meibomian lipids Exp Eye Res 90 2010 598 604
    • (2010) Exp Eye Res , vol.90 , pp. 598-604
    • Leiske, D.L.1    Raju, S.R.2    Ketelson, H.A.3    Millar, T.J.4    Fuller, G.G.5
  • 143
    • 77249142101 scopus 로고    scopus 로고
    • Tear lipids interfacial rheology: Effect of lysozyme and lens care solutions
    • T.F. Svitova, and M.C. Lin Tear lipids interfacial rheology: effect of lysozyme and lens care solutions Optom Vis Sci 87 2010 10 20
    • (2010) Optom Vis Sci , vol.87 , pp. 10-20
    • Svitova, T.F.1    Lin, M.C.2
  • 145
    • 22044439576 scopus 로고    scopus 로고
    • Insertion of tear proteins into a meibomian lipids film
    • DOI 10.1016/j.colsurfb.2005.05.011, PII S0927776505001657
    • F. Miano, M. Calcara, T.J. Millar, and V. Enea Insertion of tear proteins into a Meibomian lipids film Colloids Surf B Biointerfaces 44 2005 49 55 (Pubitemid 40968099)
    • (2005) Colloids and Surfaces B: Biointerfaces , vol.44 , Issue.1 , pp. 49-55
    • Miano, F.1    Calcara, M.2    Millar, T.J.3    Enea, V.4
  • 148
    • 0028275573 scopus 로고
    • Biophysical behaviour of the infant Meibomian lipid layer
    • DOI 10.1007/BF00919408
    • T. Kaercher, D. Mobius, and R. Welt Biophysical behaviour of the infant Meibomian lipid layer Int Ophthalmol 18 1994 15 19 (Pubitemid 24223217)
    • (1994) International Ophthalmology , vol.18 , Issue.1 , pp. 15-19
    • Kaercher, T.1    Mobius, D.2    Welt, R.3
  • 149
    • 0026733140 scopus 로고
    • Biophysical characteristics of the Meibomian lipid layer under in vitro conditions
    • T. Kaercher, D. Mobius, and R. Welt Biophysical characteristics of the Meibomian lipid layer under in vitro conditions Int Ophthalmol 16 1992 167 176
    • (1992) Int Ophthalmol , vol.16 , pp. 167-176
    • Kaercher, T.1    Mobius, D.2    Welt, R.3
  • 150
    • 77951298890 scopus 로고    scopus 로고
    • Langmuir films from human placental membranes: Preparation, rheology, transfer to alkylated glasses, and sigmoidal kinetics of alkaline phosphatase in the resultant Langmuir-Blodgett film
    • E.M. Clop, and M.A. Perillo Langmuir films from human placental membranes: preparation, rheology, transfer to alkylated glasses, and sigmoidal kinetics of alkaline phosphatase in the resultant Langmuir-Blodgett film Cell Biochem Biophys 56 2010 91 107
    • (2010) Cell Biochem Biophys , vol.56 , pp. 91-107
    • Clop, E.M.1    Perillo, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.