Impact of androgen deficiency on the lipid profiles in human meibomian gland secretions

Advances in Experimental Medicine and Biology

Volumn 506 A, Issue , 2002, Pages 449-458

  Sullivan, B D ^a   Evans, J E ^d   Dana, M R ^a,b,c   Sullivan, D A ^a,b  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICALUTAMIDE; FLUTAMIDE; LEUPRORELIN;

ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ASSOCIATION; DRY EYE; EVAPORATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE DEFICIENCY; HUMAN; LIPID COMPOSITION; MALE; MASS SPECTROMETRY; MEIBOMIAN GLAND; PRIORITY JOURNAL; SJOEGREN SYNDROME; TEAR FILM;

MEIBOMIA;

EID: 0345700810     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0717-8_63     Document Type: Conference Paper

References (15)

1. Sullivan DA, Wickham LA, Rocha EM, Krenzer KL, Sullivan BD, Steagall R, Cermak JM, Dana MR, Ullman MD, Sato EH, Gao J, Rocha FJ, Ono M, Silveira LA, Lambert RW, Kelleher RS, Tolls BD, Toda I. Androgens and dry eye in Sjögren's syndrome. Ann NY Acad Sci. 1999;876:312-324.
2. Krenzer KL, Dana MR, Ullman MD, Cermak JM, Tolls BD, Evans JE, Sullivan DA. Effect of androgen deficiency on the human meibomian gland and ocular surface. J Clin Endocr Metab. 2000;85:4874-4882.
3. Sullivan BD, Evans JE, Krenzer KL, Dana MR, Sullivan DA. Impact of anti-androgen treatment on the fatty acid profile of neutral lipids in human meibomian gland secretions. J Clin Endocr Metab. 2000;85:4866-4873.
4. Labrie F, Belanger A, Cusan L, Gomez JL, Candas B. Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocr Metab. 1997;82:2396-2402.
5. Zhu YS, Cai LQ, Cordero JJ, Canovatchel WJ, Katz MD, Imperato-McGinley J. A novel mutation in the CAG triplet region of exon 1 of androgen receptor gene causes complete androgen insensitivity syndrome in a large kindred. J Clin Endocrinol Metab. 1999;84:1590-1594.
6. Sullivan DA. Sex hormones and Sjögren's syndrome. J Rheumatol. 1997;24 (Suppl 50):17-32.
7. Sullivan DA, Bélanger A, Cermak JM, Papas AS, Sullivan RM, Yamagami H, Dana MR, Labrie F. Are women with Sjögren's syndrome androgen deficient? Invest Ophthalmol Vis Sci. 2000;Suppl. 41:S276. 1999 Physicians' Desk Reference. 53rd ed. Montvale, NJ: Medical Economics Co.
8. Sullivan DA, Bélanger A, Cermak JM, Papas AS, Sullivan RM, Yamagami H, Dana MR, Labrie F. Are women with Sjögren's syndrome androgen deficient? Invest Ophthalmol Vis Sci. 2000;Suppl. 41:S276. 1999 Physicians' Desk Reference. 53rd ed. Montvale, NJ: Medical Economics Co.
9. Sullivan BD, Evans JE, Krenzer KL, Dana MR, Sullivan DA. Complete androgen insensitivity syndrome: influence on the polar and neutral lipid profiles of human meibomian gland secretions. Manuscript submitted, 2001.
10. Sullivan BD, Evans JE, Krenzer KL, Dana MR, Sullivan DA. Effect of aging on lipid patterns in human meibomian gland secretions. Manuscript submitted. 2001.
11. Sullivan BD, Evans JE, Sullivan RM, Schaumberg DA, Dana MR, Sullivan DA. Impact of hormone replacement therapy on the lipid profile of meibomian gland secretions in postmenopausa women. Manuscript submitted, 2001.
12. Labrie F, Bélanger A, Simard J, Luu-The V, Labrie C. DHEA and peripheral androgen and estrogen formation: intracrinology. Ann NY Acad Sci. 1995;774:16-28.
13. Yamagami H, Richards SM, Sullivan BD, Liu M, Steagall RJ, Sullivan DA. Gender-associated differences in gene expression of the meibomian gland. Adv Exp Med Biol. 2001; in press.
14. Chew CKS, Hykin PG, Janswijer C, Dikstein S, Tiffany JM, Bron AJ. The casual level of meibomian lipids in humans. Curr Eye Res. 1993;12:255-259.
15. Shine WE, McCulley JP. The role of cholesterol in chronic blepharitis. Invest Ophthalmol Vis Sci. 1991;32:2272-2280.