Nitric Oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous Carcinoma Xenografts

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Cardnell, Robert J G ^a   Mikkelsen, Ross B ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; ARGINASE 2; CISPLATIN; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CONTROL; CANCER INHIBITION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CELL KILLING; CLONOGENIC ASSAY; CONTROLLED STUDY; DRUG RESPONSE; DRUG TARGETING; ENZYME INHIBITION; EX VIVO STUDY; FLUORESCENCE MICROSCOPY; FROZEN SECTION; HEAD AND NECK CARCINOMA; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIATION RESPONSE; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SQUAMOUS CELL CARCINOMA; TUMOR BLOOD FLOW; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; BLOOD VOLUME; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION DOSE; SURVIVAL; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOOD VOLUME; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; NITRIC OXIDE SYNTHASE; NITROARGININE; RADIATION DOSAGE; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79957532392     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020147     Document Type: Article

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