-
1
-
-
0029902597
-
Antivascular approaches to solid tumour therapy: Evaluation of tubulin binding agents
-
Chaplin DJ, Pettit GR, Parkins CS and Hill SA: Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents. Br J Cancer 74 (Suppl. XXVII): S86-88, 1996.
-
(1996)
Br J Cancer
, vol.74
, Issue.SUPPL. XXVII
-
-
Chaplin, D.J.1
Pettit, G.R.2
Parkins, C.S.3
Hill, S.A.4
-
3
-
-
0001360783
-
Effect of colchicines on human carcinoma
-
Seed L, Slaughter D and Limarzi LR: Effect of colchicines on human carcinoma. Surgery 7: 696-709, 1940.
-
(1940)
Surgery
, vol.7
, pp. 696-709
-
-
Seed, L.1
Slaughter, D.2
Limarzi, L.R.3
-
4
-
-
0023801309
-
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: A structure -activity study
-
Lin CM, Singh SB, Chu PS, Dempcy RO, Schmidt JM, Pettit GR et al: Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure -activity study. Mol Pharmacol 34: 200-208, 1988.
-
(1988)
Mol Pharmacol
, vol.34
, pp. 200-208
-
-
Lin, C.M.1
Singh, S.B.2
Chu, P.S.3
Dempcy, R.O.4
Schmidt, J.M.5
Pettit, G.R.6
-
5
-
-
0024513175
-
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
-
Pettit GR, Singh SB, Hamel E, Lin CM, Alberts DS and Garcia-Kendall D: Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4. Experientia 45: 209211, 1989.
-
(1989)
Experientia
, vol.45
, pp. 209211
-
-
Pettit, G.R.1
Singh, S.B.2
Hamel, E.3
Lin, C.M.4
Alberts, D.S.5
Garcia-Kendall, D.6
-
6
-
-
0028930050
-
The interaction with tubulin of a series of stilbenes based on combretastatin A-4
-
Woods JA, Hadfield JA, Pettit GR, Fox BW and McGown AT: The interaction with tubulin of a series of stilbenes based on combretastatin A-4. Br J Cancer 71: 705-711, 1995.
-
(1995)
Br J Cancer
, vol.71
, pp. 705-711
-
-
Woods, J.A.1
Hadfield, J.A.2
Pettit, G.R.3
Fox, B.W.4
McGown, A.T.5
-
7
-
-
0030951899
-
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
-
Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR and Chaplin DJ: Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 57: 1829-1834,1997.
-
(1997)
Cancer Res
, vol.57
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
Prise, V.E.3
Tozer, G.M.4
Pettit, G.R.5
Chaplin, D.J.6
-
8
-
-
0032950870
-
Anti-vascular approaches to solid tumor therapy: Evaluation of combretastatin A4 phosphate
-
Chaplin DJ, Pettit GR and Hill SA: Anti-vascular approaches to solid tumor therapy: evaluation of combretastatin A4 phosphate. Anticancer Res 19: 189-195, 1999.
-
(1999)
Anticancer Res
, vol.19
, pp. 189-195
-
-
Chaplin, D.J.1
Pettit, G.R.2
Hill, S.A.3
-
9
-
-
0032758736
-
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
-
Grosios K, Holwell SE, McGown AT, Pettit GR and Bibby MC: In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug. Br J Cancer 81: 1318-1327, 1999.
-
(1999)
Br J Cancer
, vol.81
, pp. 1318-1327
-
-
Grosios, K.1
Holwell, S.E.2
McGown, A.T.3
Pettit, G.R.4
Bibby, M.C.5
-
10
-
-
0031748452
-
Magnetic resonance imaging and spectroscopy of combretastatin A4 prodrug-induced disruption of tumor perfusion and energetic status
-
Beauregard DA, Thelwall PE, Chaplin DJ, Hill SA, Adams GE and Brindle KM: Magnetic resonance imaging and spectroscopy of combretastatin A4 prodrug-induced disruption of tumor perfusion and energetic status. Br J Cancer 77: 1761-1767, 1998.
-
(1998)
Br J Cancer
, vol.77
, pp. 1761-1767
-
-
Beauregard, D.A.1
Thelwall, P.E.2
Chaplin, D.J.3
Hill, S.A.4
Adams, G.E.5
Brindle, K.M.6
-
11
-
-
0035884395
-
The susceptibility of tumors to the antivascular drug combretastatin A4 phosphate correlates with vascular permeability
-
Beauregard DA, Hill SA, Chaplin DJ and Brindle KM: The susceptibility of tumors to the antivascular drug combretastatin A4 phosphate correlates with vascular permeability. Cancer Res 61: 6811-6815, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6811-6815
-
-
Beauregard, D.A.1
Hill, S.A.2
Chaplin, D.J.3
Brindle, K.M.4
-
12
-
-
0035019116
-
Combretastatin A-4 prodrug inhibits growth of human non-small cell lung cancer in a murine xenotransplant model
-
Böhle AS, Sipos B, Kliche U and Dohrmann P: Combretastatin A-4 prodrug inhibits growth of human non-small cell lung cancer in a murine xenotransplant model. Ann Thorac Surg 71: 1657-1665, 2001.
-
(2001)
Ann Thorac Surg
, vol.71
, pp. 1657-1665
-
-
Böhle, A.S.1
Sipos, B.2
Kliche, U.3
Dohrmann, P.4
-
13
-
-
0035233996
-
Combretastatin A-4 and doxorubicin combination treatment is effective in a preclinical model of human medullary thyroid carcinoma
-
Nelkin BD and Ball DW: Combretastatin A-4 and doxorubicin combination treatment is effective in a preclinical model of human medullary thyroid carcinoma. Oncol Rep 8: 157-160, 2001.
-
(2001)
Oncol Rep
, vol.8
, pp. 157-160
-
-
Nelkin, B.D.1
Ball, D.W.2
-
14
-
-
0035129337
-
Evaluation of combretastatin A-4 prodrug in a non-Hodgkin's lymphoma xenograft model: Preclinical efficacy
-
Nabha SM, Mohammad RM, Wall NR, Dutcher JA., Salkini BM, Pettit GR et al: Evaluation of combretastatin A-4 prodrug in a non-Hodgkin's lymphoma xenograft model: preclinical efficacy. Anticancer Drugs 12: 57-63, 2001.
-
(2001)
Anticancer Drugs
, vol.12
, pp. 57-63
-
-
Nabha, S.M.1
Mohammad, R.M.2
Wall, N.R.3
Dutcher, J.A.4
Salkini, B.M.5
Pettit, G.R.6
-
15
-
-
0033119771
-
Combretastatin A-4 phosphate as a tumor vascular-targeting agent: Early effects in tumors and normal tissues
-
Tozer GM, Prise VE, Wilson J, Locke RJ, Vojnovic B, Stratford MR et al: Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues. Cancer Res 59: 1626-1634, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 1626-1634
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Locke, R.J.4
Vojnovic, B.5
Stratford, M.R.6
-
16
-
-
0035064594
-
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumor vascular targeting activity in vivo
-
Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, Vojnovic B et al: Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumor vascular targeting activity in vivo. Anticancer Res 21(1A): 93-102, 2001.
-
(2001)
Anticancer Res
, vol.21
, Issue.1 A
, pp. 93-102
-
-
Galbraith, S.M.1
Chaplin, D.J.2
Lee, F.3
Stratford, M.R.4
Locke, R.J.5
Vojnovic, B.6
-
17
-
-
0031770618
-
The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
-
Horsman MR, Ehrnrooth E, Ladekarl M and Overgaard J: The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys 42: 895-898, 1998.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 895-898
-
-
Horsman, M.R.1
Ehrnrooth, E.2
Ladekarl, M.3
Overgaard, J.4
-
18
-
-
0035417875
-
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: Intravital microscopy and measurement of vascular permeability
-
Tozer GM, Prise VE, Wilson J, Cemazar M, Shan S, Dewhirst MW et al: Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res 61: 6413-6422, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6413-6422
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Cemazar, M.4
Shan, S.5
Dewhirst, M.W.6
-
19
-
-
17544397865
-
Vascular targeting of solid tumors: A major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyosarcomas
-
Landuyt W, Verdoes O, Darius DO, Drijkoningen M, Nuyts S, Theys J et al: Vascular targeting of solid tumors: a major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyosarcomas. Eur J Cancer 36: 1833-1843, 2000.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1833-1843
-
-
Landuyt, W.1
Verdoes, O.2
Darius, D.O.3
Drijkoningen, M.4
Nuyts, S.5
Theys, J.6
-
20
-
-
0035491773
-
Potent antimetastatic activity of combretastatin-A4
-
Griggs J, Brindle KM, Metcalfe JC, Hill SA, Smith GA, Beauregard DA et al: Potent antimetastatic activity of combretastatin-A4. Int J Oncol 19: 821-825, 2001.
-
(2001)
Int J Oncol
, vol.19
, pp. 821-825
-
-
Griggs, J.1
Brindle, K.M.2
Metcalfe, J.C.3
Hill, S.A.4
Smith, G.A.5
Beauregard, D.A.6
-
21
-
-
0034906627
-
Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model
-
Malcontenti-Wilson C, Muralldharan V, Skinner S, Christophi C, Sherris D and O'Brien PE: Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model. Clin Cancer Res 7: 1052-1060, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1052-1060
-
-
Malcontenti-Wilson, C.1
Muralldharan, V.2
Skinner, S.3
Christophi, C.4
Sherris, D.5
O'Brien, P.E.6
-
22
-
-
0035254653
-
In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment
-
Landuyt W, Ahmed B, Nuyts S, Theys J, Op de Beeck M, Rijnders A et al: In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment. Int J Radiat Oncol Biol Phys 49: 443-450, 2001.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 443-450
-
-
Landuyt, W.1
Ahmed, B.2
Nuyts, S.3
Theys, J.4
Op De Beeck, M.5
Rijnders, A.6
-
23
-
-
0031742231
-
Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy
-
Li L, Rojiani A and Siemann DW: Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy. Int J Radiat Oncol Biol Phys 42: 899-903, 1998.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 899-903
-
-
Li, L.1
Rojiani, A.2
Siemann, D.W.3
-
24
-
-
0034472914
-
Combretastatins novel vascular targeting drugs for improving anti-cancer therapy: Combretastatins and conventional therapy
-
Horsman MR, Murata R, Breidahl T, Nielsen FU, Maxwell RJ, Stodkiled-Jorgensen H et al: Combretastatins novel vascular targeting drugs for improving anti-cancer therapy: Combretastatins and conventional therapy. Adv Exp Med Biol 476: 311-323, 2000.
-
(2000)
Adv Exp Med Biol
, vol.476
, pp. 311-323
-
-
Horsman, M.R.1
Murata, R.2
Breidahl, T.3
Nielsen, F.U.4
Maxwell, R.J.5
Stodkiled-Jorgensen, H.6
-
25
-
-
0034962379
-
Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumors
-
Murata R, Siemann DW, Overgaard J and Horsman, MR: Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumors. Radiother Oncol 60: 155-161, 2001.
-
(2001)
Radiother Oncol
, vol.60
, pp. 155-161
-
-
Murata, R.1
Siemann, D.W.2
Overgaard, J.3
Horsman, M.R.4
-
26
-
-
0035889331
-
Combretastatin A-4 disodium phosphate: A vascular targeting agent that improves the anti-tumor effects of hyperthermia, radiation, and mild thermoradiotherapy
-
Murata R, Overgaard J and Horsman MR: Combretastatin A-4 disodium phosphate: a vascular targeting agent that improves the anti-tumor effects of hyperthermia, radiation, and mild thermoradiotherapy. Int J Radiat Oncol Biol 51: 1018-1024, 2001.
-
(2001)
Int J Radiat Oncol Biol
, vol.51
, pp. 1018-1024
-
-
Murata, R.1
Overgaard, J.2
Horsman, M.R.3
-
27
-
-
0034109559
-
Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma
-
Grosios K, Loadman PM, Swaine DJ, Pettit GR and Bibby MC: Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma. Anticancer Res 20: 229-233, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 229-233
-
-
Grosios, K.1
Loadman, P.M.2
Swaine, D.J.3
Pettit, G.R.4
Bibby, M.C.5
-
28
-
-
0033955698
-
The new tubulin-inhibitor combretastatin A-4 enhances thermal damage in the BT4An rat glioma
-
Eikesdal HP, Schein BC, Mella O and Dahl O: The new tubulin-inhibitor combretastatin A-4 enhances thermal damage in the BT4An rat glioma. Int J Radiat Oncol Biol Phys 46: 645-652, 2000.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.46
, pp. 645-652
-
-
Eikesdal, H.P.1
Schein, B.C.2
Mella, O.3
Dahl, O.4
-
29
-
-
0034958723
-
Cornbretastatin A-4 and hyperthermia: A potent combination for the treatment of solid tumors
-
Eikesdal HP, Bjerkvig R, Mella O and Dahl O: Cornbretastatin A-4 and hyperthermia: a potent combination for the treatment of solid tumors. Radiother Oncol 60: 147-154, 2001.
-
(2001)
Radiother Oncol
, vol.60
, pp. 147-154
-
-
Eikesdal, H.P.1
Bjerkvig, R.2
Mella, O.3
Dahl, O.4
-
30
-
-
0035874889
-
Eradication of colorectal xenografts by combined radioimmunotherapy and combretastatin A-4 3-O-phosphate
-
Pedley RB, Hill SA, Boxer GM, Flynn AA, Boden R, Watson R et al: Eradication of colorectal xenografts by combined radioimmunotherapy and combretastatin A-4 3-O-phosphate. Cancer Res 61: 4716-4722, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 4716-4722
-
-
Pedley, R.B.1
Hill, S.A.2
Boxer, G.M.3
Flynn, A.A.4
Boden, R.5
Watson, R.6
-
31
-
-
0033814533
-
Antineoplastic agents 429 Syntheses of the combretastatin A-1 and combretastatin B-1 prodrugs
-
Pettit GR, Lippert JW 3rd: Antineoplastic agents 429 Syntheses of the combretastatin A-1 and combretastatin B-1 prodrugs. Anticancer Drug Des 15: 203-216, 2000.
-
(2000)
Anticancer Drug Des
, vol.15
, pp. 203-216
-
-
Pettit, G.R.1
Lippert J.W. III2
-
32
-
-
0036253091
-
Combretastatin A-1 phosphate a novel tubulin-binding agent with in vivo antivascular effects in experimental turnouts
-
Holwell SE, Cooper PA, Grosios K, Lippert JW 3rd, Pettit GR, Shnyder SD and Bibby MC: Combretastatin A-1 phosphate a novel tubulin-binding agent with in vivo antivascular effects in experimental turnouts. Anticancer Res 22(2A): 707-711, 2002.
-
(2002)
Anticancer Res
, vol.22
, Issue.2 A
, pp. 707-711
-
-
Holwell, S.E.1
Cooper, P.A.2
Grosios, K.3
Lippert J.W. III4
Pettit, G.R.5
Shnyder, S.D.6
Bibby, M.C.7
-
33
-
-
0036324914
-
Preclinical evaluation of the antitumour activity of the novel vascular targeting agent Oxi4503
-
Hill SA, Toze GM, Pettit GR and Chaplin DJ: Preclinical evaluation of the antitumour activity of the novel vascular targeting agent Oxi4503. Anticancer Res 22(3): 1453-1458, 2002.
-
(2002)
Anticancer Res
, vol.22
, Issue.3
, pp. 1453-1458
-
-
Hill, S.A.1
Toze, G.M.2
Pettit, G.R.3
Chaplin, D.J.4
-
34
-
-
0035131992
-
Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumor and normal tissues
-
Murata R, Overgaard J and Horsman MR: Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumor and normal tissues. Int J Radiat Biol 77: 195-204, 2001.
-
(2001)
Int J Radiat Biol
, vol.77
, pp. 195-204
-
-
Murata, R.1
Overgaard, J.2
Horsman, M.R.3
-
35
-
-
0025334830
-
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy
-
Boucher Y, Baxter LT and Jain RK: Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res 50: 4478-4484, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 4478-4484
-
-
Boucher, Y.1
Baxter, L.T.2
Jain, R.K.3
-
36
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P and Jain RK: Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
37
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumor growth
-
Harris AL: Hypoxia - a key regulatory factor in tumor growth. Nature Review (Cancer) 2: 38-47, 2002.
-
(2002)
Nature Review (Cancer)
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
38
-
-
0036488496
-
Specialization of tumor vasculature
-
Ruoslahti E: Specialization of tumor vasculature. Nature Review (Cancer) 2: 83-90, 2002.
-
(2002)
Nature Review (Cancer)
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
|