Sequencing and comparative genome analysis of two pathogenic streptococcus gallolyticus subspecies: Genome plasticity, adaptation and virulence

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Lin, I Hsuan ^a,b   Liu, Tze Tze ^a   Teng, Yu Ting ^a   Wu, Hui Lun ^a   Liu, Yen Ming ^a   Wu, Keh Ming ^a   Chang, Chuan Hsiung ^a   Hsu, Ming Ta ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b ACADEMIA SINICA   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; LIPOPROTEIN; BACTERIAL DNA; BACTERIAL PROTEIN; CIRCULAR DNA;

ACUTE DISEASE; ADAPTATION; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BIOTYPE; CHRONIC DISEASE; CONTROLLED STUDY; GENE SEQUENCE; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOME ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PERSISTENT INFECTION; PHENOTYPIC PLASTICITY; RUMINANT STOMACH; STREPTOCOCCUS; STREPTOCOCCUS GALLOLYTICUS; STREPTOCOCCUS PASTEURIANUS; SUBSPECIES; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; DNA SEQUENCE; GENETICS; GENOMICS; HUMAN; METHODOLOGY; MICROBIOLOGY; MOLECULAR GENETICS; OPEN READING FRAME; PATHOGENICITY; PHYLOGENY; SPECIES DIFFERENCE; STREPTOCOCCUS INFECTION; VIRULENCE;

STREPTOCOCCUS; STREPTOCOCCUS GALLOLYTICUS; STREPTOCOCCUS PASTEURIANUS;

ADAPTATION, PHYSIOLOGICAL; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOMES, BACTERIAL; DNA, BACTERIAL; DNA, CIRCULAR; GENETIC VARIATION; GENOME, BACTERIAL; GENOMICS; HUMANS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHYLOGENY; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS; VIRULENCE;

EID: 79957514960     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020519     Document Type: Article

References (154)

1. Genta PR, Carneiro L, Genta EN, (1998) Streptococcus bovis bacteremia: unusual complications. South Med J 91: 1167-1168.
2. Jean SS, Teng LJ, Hsueh PR, Ho SW, Luh KT, (2004) Bacteremic Streptococcus bovis infections at a university hospital, 1992-2001. J Formos Med Assoc 103: 118-123.
3. Tripodi MF, Fortunato R, Utili R, Triassi M, Zarrilli R, (2005) Molecular epidemiology of Streptococcus bovis causing endocarditis and bacteraemia in Italian patients. Clin Microbiol Infect 11: 814-819.
4. Gavin PJ, Thomson RB Jr, Horng SJ, Yogev R, (2003) Neonatal sepsis caused by Streptococcus bovis variant (biotype II/2): report of a case and review. J Clin Microbiol 41: 3433-3435.
5. Onoyama S, Ogata R, Wada A, Saito M, Okada K, et al. (2009) Neonatal bacterial meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. J Med Microbiol 58: 1252-1254.
6. Sturt AS, Yang L, Sandhu K, Pei Z, Cassai N, et al. (2010) Streptococcus gallolyticus subspecies pasteurianus (biotype II/2), a newly reported cause of adult meningitis. J Clin Microbiol 48: 2247-2249.
7. Duval X, Papastamopoulos V, Longuet P, Benoit C, Perronne C, et al. (2001) Definite streptococcus bovis endocarditis: characteristics in 20 patients. Clin Microbiol Infect 7: 3-10.
8. Herrero IA, Rouse MS, Piper KE, Alyaseen SA, Steckelberg JM, et al. (2002) Reevaluation of Streptococcus bovis endocarditis cases from 1975 to 1985 by 16S ribosomal DNA sequence analysis. J Clin Microbiol 40: 3848-3850.
9. Kupferwasser I, Darius H, Muller AM, Mohr-Kahaly S, Westermeier T, et al. (1998) Clinical and morphological characteristics in Streptococcus bovis endocarditis: a comparison with other causative microorganisms in 177 cases. Heart 80: 276-280.
10. Klein RS, Recco RA, Catalano MT, Edberg SC, Casey JI, et al. (1977) Association of Streptococcus bovis with carcinoma of the colon. N Engl J Med 297: 800-802.
11. Klein RS, Catalano MT, Edberg SC, Casey JI, Steigbigel NH, (1979) Streptococcus bovis septicemia and carcinoma of the colon. Ann Intern Med 91: 560-562.
12. Darjee R, Gibb AP, (1993) Serological investigation into the association between Streptococcus bovis and colonic cancer. J Clin Pathol 46: 1116-1119.
13. Gupta A, Madani R, Mukhtar H, (2010) Streptococcus bovis endocarditis, a silent sign for colonic tumour. Colorectal Dis 12: 164-171.
14. Waisberg J, Matheus Cde O, Pimenta J, (2002) Infectious endocarditis from Streptococcus bovis associated with colonic carcinoma: case report and literature review. Arq Gastroenterol 39: 177-180.
15. Gonzlez-Quintela A, Martinez-Rey C, Castroagudin JF, Rajo-Iglesias MC, Dominguez-Santalla MJ, (2001) Prevalence of liver disease in patients with Streptococcus bovis bacteraemia. J Infect 42: 116-119.
16. Zarkin BA, Lillemoe KD, Cameron JL, Effron PN, Magnuson TH, et al. (1990) The triad of Streptococcus bovis bacteremia, colonic pathology, and liver disease. Ann Surg 211: 786-791; discussion 791-782.
17. Tripodi MF, Adinolfi LE, Ragone E, Durante Mangoni E, Fortunato R, et al. (2004) Streptococcus bovis endocarditis and its association with chronic liver disease: an underestimated risk factor. Clin Infect Dis 38: 1394-1400.
18. Facklam RR, (1972) Recognition of group D streptococcal species of human origin by biochemical and physiological tests. Appl Microbiol 23: 1131-1139.
19. Farrow JAE, Kruse J, Phillips BA, Bramley AJ, Collins MD, (1984) Taxonomic studies on Streptococcus bovis and Streptococcus equinus: Description of Streptococcus alactolyticus sp. nov. and Streptococcus saccharolyticus sp. nov. Syst Appl Microbiol 5: 467-482.
20. Parker MT, Ball LC, (1976) Streptococci and aerococci associated with systemic infection in man. J Med Microbiol 9: 275-302.
21. Beck M, Frodl R, Funke G, (2008) Comprehensive study of strains previously designated Streptococcus bovis consecutively isolated from human blood cultures and emended description of Streptococcus gallolyticus and Streptococcus infantarius subsp. coli. J Clin Microbiol 46: 2966-2972.
22. Facklam R, (2002) What happened to the streptococci: overview of taxonomic and nomenclature changes. Clin Microbiol Rev 15: 613-630.
23. Schlegel L, Grimont F, Ageron E, Grimont PA, Bouvet A, (2003) Reappraisal of the taxonomy of the Streptococcus bovis/Streptococcus equinus complex and related species: description of Streptococcus gallolyticus subsp. gallolyticus subsp. nov., S. gallolyticus subsp. macedonicus subsp. nov. and S. gallolyticus subsp. pasteurianus subsp. nov. Int J Syst Evol Microbiol 53: 631-645.
24. Poyart C, Quesne G, Trieu-Cuot P, (2002) Taxonomic dissection of the Streptococcus bovis group by analysis of manganese-dependent superoxide dismutase gene (sodA) sequences: reclassification of 'Streptococcus infantarius subsp. coli' as Streptococcus lutetiensis sp. nov. and of Streptococcus bovis biotype 11.2 as Streptococcus pasteurianus sp. nov. Int J Syst Evol Microbiol 52: 1247-1255.
25. Wirawan RE, Klesse NA, Jack RW, Tagg JR, (2006) Molecular and genetic characterization of a novel nisin variant produced by Streptococcus uberis. Appl Environ Microbiol 72: 1148-1156.
26. Knight RG, Shlaes DM, (1985) Physiological Characteristics and Deoxyribonucleic Acid Relatedness of Human Isolates of Streptococcus bovis and Streptococcus bovis (var.). Int J Syst Bacteriol 35: 357-361.
27. Delcher AL, Harmon D, Kasif S, White O, Salzberg SL, (1999) Improved microbial gene identification with GLIMMER. Nucleic Acids Res 27: 4636-4641.
28. Delcher AL, Bratke KA, Powers EC, Salzberg SL, (2007) Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics 23: 673-679.
29. Lukashin AV, Borodovsky M, (1998) GeneMark.hmm: new solutions for gene finding. Nucleic Acids Res 26: 1107-1115.
30. Tech M, Pfeifer N, Morgenstern B, Meinicke P, (2005) TICO: a tool for improving predictions of prokaryotic translation initiation sites. Bioinformatics 21: 3568-3569.
31. Aoki-Kinoshita KF, Kanehisa M, (2007) Gene annotation and pathway mapping in KEGG. Methods Mol Biol 396: 71-91.
32. Jensen LJ, Kuhn M, Stark M, Chaffron S, Creevey C, et al. (2009) STRING 8-a global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res 37: D412-416.
33. Eddy SR, (2008) A probabilistic model of local sequence alignment that simplifies statistical significance estimation. PLoS Comput Biol 4: e1000069.
34. Marchler-Bauer A, Anderson JB, Chitsaz F, Derbyshire MK, DeWeese-Scott C, et al. (2009) CDD: specific functional annotation with the Conserved Domain Database. Nucleic Acids Res 37: D205-210.
35. Finn RD, Mistry J, Tate J, Coggill P, Heger A, et al. (2010) The Pfam protein families database. Nucleic Acids Res 38: D211-222.
36. Gardy JL, Laird MR, Chen F, Rey S, Walsh CJ, et al. (2005) PSORTb v.2.0: expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis. Bioinformatics 21: 617-623.
37. Bendtsen JD, Nielsen H, von Heijne G, Brunak S, (2004) Improved prediction of signal peptides: SignalP 3.0. J Mol Biol 340: 783-795.
38. Juncker AS, Willenbrock H, Von Heijne G, Brunak S, Nielsen H, et al. (2003) Prediction of lipoprotein signal peptides in Gram-negative bacteria. Protein Sci 12: 1652-1662.
39. Krogh A, Larsson B, von Heijne G, Sonnhammer EL, (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 305: 567-580.
40. Rice P, Longden I, Bleasby A, (2000) EMBOSS: the European Molecular Biology Open Software Suite. Trends Genet 16: 276-277.
41. Puigbo P, Bravo IG, Garcia-Vallve S, (2008) E-CAI: a novel server to estimate an expected value of Codon Adaptation Index (eCAI). BMC Bioinformatics 9: 65.
42. Grissa I, Vergnaud G, Pourcel C, (2007) CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats. Nucleic Acids Res 35: W52-57.
43. Laslett D, Canback B, (2004) ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences. Nucleic Acids Res 32: 11-16.
44. Lowe TM, Eddy SR, (1997) tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res 25: 955-964.
45. Lagesen K, Hallin P, Rodland EA, Staerfeldt HH, Rognes T, et al. (2007) RNAmmer: consistent and rapid annotation of ribosomal RNA genes. Nucleic Acids Res 35: 3100-3108.
46. Rutherford K, Parkhill J, Crook J, Horsnell T, Rice P, et al. (2000) Artemis: sequence visualization and annotation. Bioinformatics 16: 944-945.
47. Carver T, Thomson N, Bleasby A, Berriman M, Parkhill J, (2009) DNAPlotter: circular and linear interactive genome visualization. Bioinformatics 25: 119-120.
48. Darling AC, Mau B, Blattner FR, Perna NT, (2004) Mauve: multiple alignment of conserved genomic sequence with rearrangements. Genome Res 14: 1394-1403.
49. Tamura K, Dudley J, Nei M, Kumar S, (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24: 1596-1599.
50. Katoh K, Kuma K, Toh H, Miyata T, (2005) MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res 33: 511-518.
51. Zmasek CM, Eddy SR, (2001) ATV: display and manipulation of annotated phylogenetic trees. Bioinformatics 17: 383-384.
52. Unite de Biologie des Bacteries Intracellulaires IP, France (2010) Streptococcus gallolyticus subsp. gallolyticus UCN34 Genome Project.
53. Rusniok C, Couve E, Da Cunha V, El Gana R, Zidane N, et al. (2010) Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis. J Bacteriol 192: 2266-2276.
54. Sharp PM, Li WH, (1987) The codon Adaptation Index-a measure of directional synonymous codon usage bias, and its potential applications. Nucleic Acids Res 15: 1281-1295.
55. Bizzini A, Zhao C, Budin-Verneuil A, Sauvageot N, Giard JC, et al. (2010) Glycerol is metabolized in a complex and strain-dependent manner in Enterococcus faecalis. J Bacteriol 192: 779-785.
56. Ferguson GP, Totemeyer S, MacLean MJ, Booth IR, (1998) Methylglyoxal production in bacteria: suicide or survival? Arch Microbiol 170: 209-218.
57. Henstra SA, Tolner B, ten Hoeve Duurkens RH, Konings WN, Robillard GT, (1996) Cloning, expression, and isolation of the mannitol transport protein from the thermophilic bacterium Bacillus stearothermophilus. J Bacteriol 178: 5586-5591.
58. Behrens S, Mitchell W, Bahl H, (2001) Molecular analysis of the mannitol operon of Clostridium acetobutylicum encoding a phosphotransferase system and a putative PTS-modulated regulator. Microbiology 147: 75-86.
59. Dalrymple BP, Swadling Y, Cybinski DH, Xue GP, (1996) Cloning of a gene encoding cinnamoyl ester hydrolase from the ruminal bacterium Butyrivibrio fibrisolvens E14 by a novel method. FEMS Microbiol Lett 143: 115-120.
60. Bhat TK, Singh B, Sharma OP, (1998) Microbial degradation of tannins-a current perspective. Biodegradation 9: 343-357.
61. Noguchi N, Ohashi T, Shiratori T, Narui K, Hagiwara T, et al. (2007) Association of tannase-producing Staphylococcus lugdunensis with colon cancer and characterization of a novel tannase gene. J Gastroenterol 42: 346-351.
62. Ellmerich S, Scholler M, Duranton B, Gosse F, Galluser M, et al. (2000) Promotion of intestinal carcinogenesis by Streptococcus bovis. Carcinogenesis 21: 753-756.
63. Avila M, Jaquet M, Moine D, Requena T, Pelaez C, et al. (2009) Physiological and biochemical characterization of the two alpha-L-rhamnosidases of Lactobacillus plantarum NCC245. Microbiology 155: 2739-2749.
64. Abdel-Mawgoud AM, Lepine F, Deziel E, (2010) Rhamnolipids: diversity of structures, microbial origins and roles. Appl Microbiol Biotechnol 86: 1323-1336.
65. Cui Z, Maruyama Y, Mikami B, Hashimoto W, Murata K, (2006) Crystallization and preliminary crystallographic analysis of the family GH78 alpha-L-rhamnosidase RhaB from Bacillus sp. GL1. Acta Crystallogr Sect F Struct Biol Cryst Commun 62: 646-648.
66. Rivolta C, Soldo B, Lazarevic V, Joris B, Mauel C, et al. (1998) A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element. Microbiology 144 (Pt 4): 877-884.
67. Sambandamurthy VK, Wang X, Chen B, Russell RG, Derrick S, et al. (2002) A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nat Med 8: 1171-1174.
68. Tanaka T, Tateno Y, Gojobori T, (2005) Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol 22: 243-250.
69. Strohmeier M, Raschle T, Mazurkiewicz J, Rippe K, Sinning I, et al. (2006) Structure of a bacterial pyridoxal 5′-phosphate synthase complex. Proc Natl Acad Sci U S A 103: 19284-19289.
70. Gutierrez-Preciado A, Yanofsky C, Merino E, (2007) Comparison of tryptophan biosynthetic operon regulation in different Gram-positive bacterial species. Trends Genet 23: 422-426.
71. Novak R, Charpentier E, Braun JS, Tuomanen E, (2000) Signal transduction by a death signal peptide: uncovering the mechanism of bacterial killing by penicillin. Mol Cell 5: 49-57.
72. Novak R, Henriques B, Charpentier E, Normark S, Tuomanen E, (1999) Emergence of vancomycin tolerance in Streptococcus pneumoniae. Nature 399: 590-593.
73. Mitchell LS, Tuomanen EI, (2002) Molecular analysis of antibiotic tolerance in pneumococci. Int J Med Microbiol 292: 75-79.
74. Haas W, Sublett J, Kaushal D, Tuomanen EI, (2004) Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance. J Bacteriol 186: 8463-8471.
75. Kjos M, Snipen L, Salehian Z, Nes IF, Diep DB, (2010) The abi proteins and their involvement in bacteriocin self-immunity. J Bacteriol 192: 2068-2076.
76. D'Souza C, Nakano MM, Zuber P, (1994) Identification of comS, a gene of the srfA operon that regulates the establishment of genetic competence in Bacillus subtilis. Proc Natl Acad Sci U S A 91: 9397-9401.
77. Hamoen LW, Eshuis H, Jongbloed J, Venema G, van Sinderen D, (1995) A small gene, designated comS, located within the coding region of the fourth amino acid-activation domain of srfA, is required for competence development in Bacillus subtilis. Mol Microbiol 15: 55-63.
78. Moscoso M, Claverys JP, (2004) Release of DNA into the medium by competent Streptococcus pneumoniae: kinetics, mechanism and stability of the liberated DNA. Mol Microbiol 54: 783-794.
79. Kreth J, Merritt J, Shi W, Qi F, (2005) Co-ordinated bacteriocin production and competence development: a possible mechanism for taking up DNA from neighbouring species. Mol Microbiol 57: 392-404.
80. van der Ploeg JR, (2005) Regulation of bacteriocin production in Streptococcus mutans by the quorum-sensing system required for development of genetic competence. J Bacteriol 187: 3980-3989.
81. Perry JA, Jones MB, Peterson SN, Cvitkovitch DG, Levesque CM, (2009) Peptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence. Mol Microbiol 72: 905-917.
82. Fisher JF, Meroueh SO, Mobashery S, (2005) Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity. Chem Rev 105: 395-424.
83. Massova I, Mobashery S, (1998) Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases. Antimicrob Agents Chemother 42: 1-17.
84. Ghuysen JM, (1994) Molecular structures of penicillin-binding proteins and beta-lactamases. Trends Microbiol 2: 372-380.
85. Haft DH, Selengut J, Mongodin EF, Nelson KE, (2005) A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. PLoS Comput Biol 1: e60.
86. Lillestol RK, Redder P, Garrett RA, Brugger K, (2006) A putative viral defence mechanism in archaeal cells. Archaea 2: 59-72.
87. Lillestol RK, Shah SA, Brugger K, Redder P, Phan H, et al. (2009) CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties. Mol Microbiol 72: 259-272.
88. Hale C, Kleppe K, Terns RM, Terns MP, (2008) Prokaryotic silencing (psi)RNAs in Pyrococcus furiosus. RNA 14: 2572-2579.
89. Llull D, Lopez R, Garcia E, (2001) Genetic bases and medical relevance of capsular polysaccharide biosynthesis in pathogenic streptococci. Curr Mol Med 1: 475-491.
90. Lowe BA, Miller JD, Neely MN, (2007) Analysis of the polysaccharide capsule of the systemic pathogen Streptococcus iniae and its implications in virulence. Infect Immun 75: 1255-1264.
91. Aanensen DM, Mavroidi A, Bentley SD, Reeves PR, Spratt BG, (2007) Predicted functions and linkage specificities of the products of the Streptococcus pneumoniae capsular biosynthetic loci. J Bacteriol 189: 7856-7876.
92. Bentley SD, Aanensen DM, Mavroidi A, Saunders D, Rabbinowitsch E, et al. (2006) Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet 2: e31.
93. Mavroidi A, Aanensen DM, Godoy D, Skovsted IC, Kaltoft MS, et al. (2007) Genetic relatedness of the Streptococcus pneumoniae capsular biosynthetic loci. J Bacteriol 189: 7841-7855.
94. Varvio SL, Auranen K, Arjas E, Makela PH, (2009) Evolution of the capsular regulatory genes in Streptococcus pneumoniae. J Infect Dis 200: 1144-1151.
95. Navarre WW, Schneewind O, (1999) Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol Mol Biol Rev 63: 174-229.
96. Mazmanian SK, Ton-That H, Schneewind O, (2001) Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus. Mol Microbiol 40: 1049-1057.
97. Ton-That H, Marraffini LA, Schneewind O, (2004) Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochim Biophys Acta 1694: 269-278.
98. Sutcliffe IC, Russell RR, (1995) Lipoproteins of gram-positive bacteria. J Bacteriol 177: 1123-1128.
99. Sun X, Ge R, Chiu JF, Sun H, He QY, (2008) Lipoprotein MtsA of MtsABC in Streptococcus pyogenes primarily binds ferrous ion with bicarbonate as a synergistic anion. FEBS Lett 582: 1351-1354.
100. Bray BA, Sutcliffe IC, Harrington DJ, (2009) Expression of the MtsA lipoprotein of Streptococcus agalactiae A909 is regulated by manganese and iron. Antonie Van Leeuwenhoek 95: 101-109.
101. Burnette-Curley D, Wells V, Viscount H, Munro CL, Fenno JC, et al. (1995) FimA, a major virulence factor associated with Streptococcus parasanguis endocarditis. Infect Immun 63: 4669-4674.
102. Viscount HB, Munro CL, Burnette-Curley D, Peterson DL, Macrina FL, (1997) Immunization with FimA protects against Streptococcus parasanguis endocarditis in rats. Infect Immun 65: 994-1002.
103. Vollmer T, Hinse D, Kleesiek K, Dreier J, (2010) Interactions between endocarditis-derived Streptococcus gallolyticus subsp. gallolyticus isolates and human endothelial cells. BMC Microbiol 10: 78.
104. Ganeshkumar N, Hannam PM, Kolenbrander PE, McBride BC, (1991) Nucleotide sequence of a gene coding for a saliva-binding protein (SsaB) from Streptococcus sanguis 12 and possible role of the protein in coaggregation with actinomyces. Infect Immun 59: 1093-1099.
105. Das S, Kanamoto T, Ge X, Xu P, Unoki T, et al. (2009) Contribution of lipoproteins and lipoprotein processing to endocarditis virulence in Streptococcus sanguinis. J Bacteriol 191: 4166-4179.
106. Kolenbrander PE, Andersen RN, Ganeshkumar N, (1994) Nucleotide sequence of the Streptococcus gordonii PK488 coaggregation adhesin gene, scaA, and ATP-binding cassette. Infect Immun 62: 4469-4480.
107. Berry AM, Paton JC, (1996) Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae. Infect Immun 64: 5255-5262.
108. Rajam G, Anderton JM, Carlone GM, Sampson JS, Ades EW, (2008) Pneumococcal surface adhesin A (PsaA): a review. Crit Rev Microbiol 34: 131-142.
109. Kitten T, Munro CL, Michalek SM, Macrina FL, (2000) Genetic characterization of a Streptococcus mutans LraI family operon and role in virulence. Infect Immun 68: 4441-4451.
110. Paik S, Brown A, Munro CL, Cornelissen CN, Kitten T, (2003) The sloABCR operon of Streptococcus mutans encodes an Mn and Fe transport system required for endocarditis virulence and its Mn-dependent repressor. J Bacteriol 185: 5967-5975.
111. Lowe AM, Lambert PA, Smith AW, (1995) Cloning of an Enterococcus faecalis endocarditis antigen: homology with adhesins from some oral streptococci. Infect Immun 63: 703-706.
112. Singh KV, Coque TM, Weinstock GM, Murray BE, (1998) In vivo testing of an Enterococcus faecalis efaA mutant and use of efaA homologs for species identification. FEMS Immunol Med Microbiol 21: 323-331.
113. Semedo T, Santos MA, Lopes MF, Figueiredo Marques JJ, Barreto Crespo MT, et al. (2003) Virulence factors in food, clinical and reference Enterococci: A common trait in the genus? Syst Appl Microbiol 26: 13-22.
114. Maisey HC, Hensler M, Nizet V, Doran KS, (2007) Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. J Bacteriol 189: 1464-1467.
115. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, et al. (2008) A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J 22: 1715-1724.
116. Konto-Ghiorghi Y, Mairey E, Mallet A, Dumenil G, Caliot E, et al. (2009) Dual role for pilus in adherence to epithelial cells and biofilm formation in Streptococcus agalactiae. PLoS Pathog 5: e1000422.
117. Shibata Y, Kawada M, Nakano Y, Toyoshima K, Yamashita Y, (2005) Identification and characterization of an autolysin-encoding gene of Streptococcus mutans. Infect Immun 73: 3512-3520.
118. Ahn SJ, Burne RA, (2006) The atlA operon of Streptococcus mutans: role in autolysin maturation and cell surface biogenesis. J Bacteriol 188: 6877-6888.
119. Jung CJ, Zheng QH, Shieh YH, Lin CS, Chia JS, (2009) Streptococcus mutans autolysin AtlA is a fibronectin-binding protein and contributes to bacterial survival in the bloodstream and virulence for infective endocarditis. Mol Microbiol 74: 888-902.
120. Kuramitsu HK, (1993) Virulence factors of mutans streptococci: role of molecular genetics. Crit Rev Oral Biol Med 4: 159-176.
121. Yamashita Y, Bowen WH, Burne RA, Kuramitsu HK, (1993) Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect Immun 61: 3811-3817.
122. Shun CT, Lu SY, Yeh CY, Chiang CP, Chia JS, et al. (2005) Glucosyltransferases of viridans streptococci are modulins of interleukin-6 induction in infective endocarditis. Infect Immun 73: 3261-3270.
123. Munro CL, Macrina FL, (1993) Sucrose-derived exopolysaccharides of Streptococcus mutans V403 contribute to infectivity in endocarditis. Mol Microbiol 8: 133-142.
124. Nomura R, Nakano K, Nemoto H, Fujita K, Inagaki S, et al. (2006) Isolation and characterization of Streptococcus mutans in heart valve and dental plaque specimens from a patient with infective endocarditis. J Med Microbiol 55: 1135-1140.
125. Nemoto H, Nakano K, Nomura R, Ooshima T, (2008) Molecular characterization of Streptococcus mutans strains isolated from the heart valve of an infective endocarditis patient. J Med Microbiol 57: 891-895.
126. Havarstein LS, Hakenbeck R, Gaustad P, (1997) Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges. J Bacteriol 179: 6589-6594.
127. Kleerebezem M, Quadri LE, Kuipers OP, de Vos WM, (1997) Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol Microbiol 24: 895-904.
128. Chen I, Provvedi R, Dubnau D, (2006) A macromolecular complex formed by a pilin-like protein in competent Bacillus subtilis. J Biol Chem 281: 21720-21727.
129. Lory S, (1998) Secretion of proteins and assembly of bacterial surface organelles: shared pathways of extracellular protein targeting. Curr Opin Microbiol 1: 27-35.
130. Collyn F, Lety MA, Nair S, Escuyer V, Ben Younes A, et al. (2002) Yersinia pseudotuberculosis harbors a type IV pilus gene cluster that contributes to pathogenicity. Infect Immun 70: 6196-6205.
131. Kulkarni R, Dhakal BK, Slechta ES, Kurtz Z, Mulvey MA, et al. (2009) Roles of putative type II secretion and type IV pilus systems in the virulence of uropathogenic Escherichia coli. PLoS One 4: e4752.
132. Whitchurch CB, Tolker-Nielsen T, Ragas PC, Mattick JS, (2002) Extracellular DNA required for bacterial biofilm formation. Science 295: 1487.
133. Hall-Stoodley L, Stoodley P, (2009) Evolving concepts in biofilm infections. Cell Microbiol 11: 1034-1043.
134. Moscoso M, Garcia E, Lopez R, (2009) Pneumococcal biofilms. Int Microbiol 12: 77-85.
135. Costerton JW, Stewart PS, Greenberg EP, (1999) Bacterial biofilms: a common cause of persistent infections. Science 284: 1318-1322.
136. Bogaert D, De Groot R, Hermans PW, (2004) Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis 4: 144-154.
137. Mah TF, O'Toole GA, (2001) Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 9: 34-39.
138. Nomura R, Nakano K, Ooshima T, (2004) Contribution of glucan-binding protein C of Streptococcus mutans to bacteremia occurrence. Arch Oral Biol 49: 783-788.
139. Cho KH, Caparon MG, (2005) Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes. Mol Microbiol 57: 1545-1556.
140. Idone V, Brendtro S, Gillespie R, Kocaj S, Peterson E, et al. (2003) Effect of an orphan response regulator on Streptococcus mutans sucrose-dependent adherence and cariogenesis. Infect Immun 71: 4351-4360.
141. Senadheera MD, Guggenheim B, Spatafora GA, Huang YC, Choi J, et al. (2005) A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development. J Bacteriol 187: 4064-4076.
142. Kohanski MA, Dwyer DJ, Collins JJ, (2010) How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol 8: 423-435.
143. Lewis K, (2000) Programmed death in bacteria. Microbiol Mol Biol Rev 64: 503-514.
144. Bayles KW, (2007) The biological role of death and lysis in biofilm development. Nat Rev Microbiol 5: 721-726.
145. Majcherczyk PA, Langen H, Heumann D, Fountoulakis M, Glauser MP, et al. (1999) Digestion of Streptococcus pneumoniae cell walls with its major peptidoglycan hydrolase releases branched stem peptides carrying proinflammatory activity. J Biol Chem 274: 12537-12543.
146. Ginsburg I, (2002) The role of bacteriolysis in the pathophysiology of inflammation, infection and post-infectious sequelae. APMIS 110: 753-770.
147. Ahn SJ, Rice KC, Oleas J, Bayles KW, Burne RA, (2010) The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals. Microbiology 156: 3136-3147.
148. Simeone R, Bottai D, Brosch R, (2009) ESX/type VII secretion systems and their role in host-pathogen interaction. Curr Opin Microbiol 12: 4-10.
149. Abdallah AM, Gey van Pittius NC, Champion PA, Cox J, Luirink J, et al. (2007) Type VII secretion-mycobacteria show the way. Nat Rev Microbiol 5: 883-891.
150. Bitter W, Houben EN, Bottai D, Brodin P, Brown EJ, et al. (2009) Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog 5: e1000507.
151. Pallen MJ, (2002) The ESAT-6/WXG100 superfamily - and a new Gram-positive secretion system? Trends Microbiol 10: 209-212.
152. Shukla A, Pallen M, Anthony M, White SA, (2010) The homodimeric GBS1074 from Streptococcus agalactiae. Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 1421-1425.
153. Baylor College of Medicine HGSC, USA (2010) Streptococcus gallolyticus subsp. gallolyticus TX20005 Genome Project.
154. Sillanpaa J, Nallapareddy SR, Qin X, Singh KV, Muzny DM, et al. (2009) A collagen-binding adhesin, Acb, and ten other putative MSCRAMM and pilus family proteins of Streptococcus gallolyticus subsp. gallolyticus (Streptococcus bovis Group, biotype I). J Bacteriol 191: 6643-6653.