메뉴 건너뛰기




Volumn 134, Issue 5, 2011, Pages 1277-1292

Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy

Author keywords

cervical spondylotic myelopathy; Fas mediated apoptosis; inflammation

Indexed keywords

FAS ANTIBODY;

EID: 79957474401     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr054     Document Type: Article
Times cited : (119)

References (55)
  • 1
    • 33646575557 scopus 로고    scopus 로고
    • Inhibition of Fas-mediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury
    • Ackery A, Robins S, Fehlings MG. Inhibition of Fas-mediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury. J Neurotrauma 2006; 23: 604-16. (Pubitemid 43728050)
    • (2006) Journal of Neurotrauma , vol.23 , Issue.5 , pp. 604-616
    • Ackery, A.1    Robins, S.2    Fehlings, M.G.3
  • 2
    • 49749108561 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist attenuates the severity of spinal cord ischemic injury in rabbits
    • Akuzawa S, Kazui T, Shi E, Yamashita K, Bashar AH, Terada H. Interleukin-1 receptor antagonist attenuates the severity of spinal cord ischemic injury in rabbits. J Vasc Surg 2008; 48: 694-700.
    • (2008) J Vasc Surg , vol.48 , pp. 694-700
    • Akuzawa, S.1    Kazui, T.2    Shi, E.3    Yamashita, K.4    Bashar, A.H.5    Terada, H.6
  • 3
    • 0034048666 scopus 로고    scopus 로고
    • Interferon-γ induces apoptosis and augments the expression of Fas and Fas ligand by microglia in vitro
    • DOI 10.1006/exnr.1999.7345
    • Badie B, Schartner J, Vorpahl J, Preston K. Interferon-gamma induces apoptosis and augments the expression of Fas and Fas ligand by microglia in vitro. Exp Neurol 2000; 162: 290-6. (Pubitemid 30217724)
    • (2000) Experimental Neurology , vol.162 , Issue.2 , pp. 290-296
    • Badie, B.1    Schartner, J.2    Vorpahl, J.3    Preston, K.4
  • 4
    • 0032030751 scopus 로고    scopus 로고
    • CD95-CD95L: Can the brain learn from the immune system?
    • DOI 10.1016/S0166-2236(97)01180-6
    • Becher B, Barker PA, Owens T, Antel JP. CD95-CD95L: Can the brain learn from the immune system? Trends Neurosci 1998; 21: 114-7. (Pubitemid 28080673)
    • (1998) Trends in Neurosciences , vol.21 , Issue.3 , pp. 114-117
    • Becher, B.1    Owens, T.2    Antel, J.P.3    Barker, P.A.4
  • 5
    • 0023765010 scopus 로고
    • The pathophysiology of cervical spondylosis and myelopathy
    • Bohlman HH, Emery SE. The pathophysiology of cervical spondylosis and myelopathy. Spine 1988; 13: 843-6.
    • (1988) Spine , vol.13 , pp. 843-846
    • Bohlman, H.H.1    Emery, S.E.2
  • 6
    • 34447634505 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury
    • Buss A, Pech K, Kakulas BA, Martin D, Schoenen J, Noth J, et al. Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury. BMC Neurol 2007; 7: 17.
    • (2007) BMC Neurol , vol.7 , pp. 17
    • Buss, A.1    Pech, K.2    Kakulas, B.A.3    Martin, D.4    Schoenen, J.5    Noth, J.6
  • 8
    • 0035961212 scopus 로고    scopus 로고
    • Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat
    • DOI 10.1016/S0306-4522(00)00538-8, PII S0306452200005388
    • Casha S, Yu WR, Fehlings MG. Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat. Neuroscience 2001; 103: 203-18. (Pubitemid 32304360)
    • (2001) Neuroscience , vol.103 , Issue.1 , pp. 203-218
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 9
    • 27744542561 scopus 로고    scopus 로고
    • FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury
    • DOI 10.1016/j.expneurol.2005.08.020, PII S0014488605003134
    • Casha S, Yu WR, Fehlings MG. FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury. Exp Neurol 2005; 196: 390-400. (Pubitemid 41607828)
    • (2005) Experimental Neurology , vol.196 , Issue.2 , pp. 390-400
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 10
    • 0242459197 scopus 로고    scopus 로고
    • Induction of intercellular adhesion molecule-1 by Fas ligation: Proinflammatory roles of Fas in human astroglioma cells
    • DOI 10.1016/j.neulet.2003.08.019
    • Choi K, Benveniste EN, Choi C. Induction of intercellular adhesion molecule-1 by Fas ligation: Proinflammatory roles of Fas in human astroglioma cells. Neurosci Lett 2003; 352: 21-4. (Pubitemid 37412316)
    • (2003) Neuroscience Letters , vol.352 , Issue.1 , pp. 21-24
    • Choi, K.1    Benveniste, E.N.2    Choi, C.3
  • 12
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • DOI 10.1038/nm0197-73
    • Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997; 3: 73-6. (Pubitemid 27019144)
    • (1997) Nature Medicine , vol.3 , Issue.1 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3    Masters, J.N.4    Beattie, M.S.5
  • 13
    • 0019938340 scopus 로고
    • An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks
    • DOI 10.1016/0014-4886(82)90234-5
    • de Medinaceli L, Freed WJ, Wyatt RJ. An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks. Exp Neurol 1982; 77: 634-43. (Pubitemid 12011176)
    • (1982) Experimental Neurology , vol.77 , Issue.3 , pp. 634-643
    • De Medinaceli, L.1    Freed, W.J.2    Wyatt, R.J.3
  • 17
    • 0032535533 scopus 로고    scopus 로고
    • A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury
    • DOI 10.1097/00007632-199812150-00012
    • Fehlings MG, Skaf G. A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury. Spine 1998; 23: 2730-7. (Pubitemid 29013985)
    • (1998) Spine , vol.23 , Issue.24 , pp. 2730-2737
    • Fehlings, M.G.1    Skaf, G.2
  • 18
    • 0033968517 scopus 로고    scopus 로고
    • Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain
    • Felderhoff-Mueser U, Taylor DL, Greenwood K, Kozma M, Stibenz D, Joashi UC, et al. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain. Brain Pathol 2000; 10: 17-29. (Pubitemid 30056390)
    • (2000) Brain Pathology , vol.10 , Issue.1 , pp. 17-29
    • Felderhoff-Mueser, U.1    Taylor, D.L.2    Greenwood, K.3    Kozma, M.4    Stibenz, D.5    Joashi, U.C.6    Edwards, A.D.7    Mehmet, H.8
  • 20
    • 0027343152 scopus 로고
    • Microglial secretion products and their impact on the nervous system
    • Giulian D, Corpuz M. Microglial secretion products and their impact on the nervous system. Adv Neurol 1993; 59: 315-20.
    • (1993) Adv Neurol , vol.59 , pp. 315-320
    • Giulian, D.1    Corpuz, M.2
  • 21
    • 0141497935 scopus 로고    scopus 로고
    • Differential temporal expression of matrix metalloproteinases after spinal cord injury: Relationship to revascularization and wound healing
    • Goussev S, Hsu JY, Lin Y, Tjoa T, Maida N, Werb Z, et al. Differential temporal expression of matrix metalloproteinases after spinal cord injury: Relationship to revascularization and wound healing. J Neurosurg 2003; 99: 188-97.
    • (2003) J Neurosurg , vol.99 , pp. 188-197
    • Goussev, S.1    Hsu, J.Y.2    Lin, Y.3    Tjoa, T.4    Maida, N.5    Werb, Z.6
  • 22
    • 0029983883 scopus 로고    scopus 로고
    • Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats
    • Hamada Y, Ikata T, Katoh S, Nakauchi K, Niwa M, Kawai Y, et al. Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats. J Neurochem 1996; 66: 1525-31. (Pubitemid 26090555)
    • (1996) Journal of Neurochemistry , vol.66 , Issue.4 , pp. 1525-1531
    • Hamada, Y.1    Ikata, T.2    Katoh, S.3    Nakauchi, K.4    Niwa, M.5    Kawai, Y.6    Fukuzawa, K.7
  • 23
    • 0038340422 scopus 로고    scopus 로고
    • Post-traumatic inflammation following spinal cord injury
    • DOI 10.1038/sj.sc.3101483
    • Hausmann ON. Post-traumatic inflammation following spinal cord injury. Spinal Cord 2003; 41: 369-78. (Pubitemid 36819586)
    • (2003) Spinal Cord , vol.41 , Issue.7 , pp. 369-378
    • Hausmann, O.N.1
  • 24
    • 0034663946 scopus 로고    scopus 로고
    • Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1β is required for the production of ciliary neurotrophic factor
    • Herx LM, Rivest S, Yong VW. Central nervous system-initiated inflammation and neurotrophism in trauma: IL-1 beta is required for the production of ciliary neurotrophic factor. J Immunol 2000; 165: 2232-9. (Pubitemid 30643173)
    • (2000) Journal of Immunology , vol.165 , Issue.4 , pp. 2232-2239
    • Herx, L.M.1    Rivest, S.2    Yong, V.W.3
  • 25
    • 22244481544 scopus 로고    scopus 로고
    • Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury
    • DOI 10.1523/JNEUROSCI.0305-05.2005
    • Jones TB, Hart RP, Popovich PG. Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury. J Neurosci 2005; 25: 6576-83. (Pubitemid 40995289)
    • (2005) Journal of Neuroscience , vol.25 , Issue.28 , pp. 6576-6583
    • Jones, T.B.1    Hart, R.P.2    Popovich, P.G.3
  • 28
    • 76949101422 scopus 로고    scopus 로고
    • CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site
    • Letellier E, Kumar S, Sancho-Martinez I, Krauth S, Funke-Kaiser A, Laudenklos S, et al. CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site. Immunity 2010; 32: 240-52.
    • (2010) Immunity , Issue.32 , pp. 240-252
    • Letellier, E.1    Kumar, S.2    Sancho-Martinez, I.3    Krauth, S.4    Funke-Kaiser, A.5    Laudenklos, S.6
  • 30
    • 0032828302 scopus 로고    scopus 로고
    • Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord
    • DOI 10.1007/s004010051112
    • Li GL, Farooque M, Holtz A, Olsson Y. Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord. Acta Neuropathol 1999; 98: 473-80. (Pubitemid 29476166)
    • (1999) Acta Neuropathologica , vol.98 , Issue.5 , pp. 473-480
    • Li, G.L.1    Farooque, M.2    Holtz, A.3    Olsson, Y.4
  • 31
    • 0031783704 scopus 로고    scopus 로고
    • Apoptosis as a mechanism of neuronal cell death following acute experimental spinal cord injury
    • Lou J, Lenke LG, Ludwig FJ, O'Brian MF. Apoptosis as a mechanism of neuronal cell death following acute experimental spinal cord injury. Spinal Cord 1998; 36: 683-90. (Pubitemid 28479074)
    • (1998) Spinal Cord , vol.36 , Issue.10 , pp. 683-690
    • Lou, J.1    Lenke, L.G.2    Ludwig, F.J.3    O'Brien, M.F.4
  • 32
    • 0033756931 scopus 로고    scopus 로고
    • Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: A potential new anti-inflammatory treatment
    • Mabon PJ, Weaver LC, Dekaban GA. Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: A potential new anti-inflammatory treatment. Exp Neurol 2000; 166: 52-64.
    • (2000) Exp Neurol , vol.166 , pp. 52-64
    • Mabon, P.J.1    Weaver, L.C.2    Dekaban, G.A.3
  • 35
  • 37
    • 0033712614 scopus 로고    scopus 로고
    • Production of neurotrophins by activated T cells: Implications for neuroprotective autoimmunity
    • Moalem G, Gdalyahu A, Shani Y, Otten U, Lazarovici P, Cohen IR, et al. Production of neurotrophins by activated T cells: Implications for neuroprotective autoimmunity. J Autoimmun 2000; 15: 331-45.
    • (2000) J Autoimmun , vol.15 , pp. 331-345
    • Moalem, G.1    Gdalyahu, A.2    Shani, Y.3    Otten, U.4    Lazarovici, P.5    Cohen, I.R.6
  • 39
    • 0035102552 scopus 로고    scopus 로고
    • Immune privilege or inflammation? Insights into the Fas ligand enigma
    • DOI 10.1038/85395
    • O'Connell J, Houston A, Bennett MW, O'Sullivan GC, Shanahan F. Immune privilege or inflammation? Insights into the Fas ligand enigma. Nat Med 2001; 7: 271-4. (Pubitemid 32224332)
    • (2001) Nature Medicine , vol.7 , Issue.3 , pp. 271-274
    • O'connell, J.1    Houston, A.2    Bennett, M.W.3    O'sullivan, G.C.4    Shanahan, F.5
  • 40
    • 0029842168 scopus 로고    scopus 로고
    • Symptoms and pathological anatomy of the degenerative cervical spine
    • Ohwada T, Ohkouchi T, Yamamoto T, Ono K. [Symptoms and pathological anatomy of the degenerative cervical spine]. Orthopade 1996; 25: 496-504.
    • (1996) Orthopade , vol.25 , pp. 496-504
    • Ohwada, T.1    Ohkouchi, T.2    Yamamoto, T.3    Ono, K.4
  • 42
    • 58949105069 scopus 로고    scopus 로고
    • The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington's disease are task- and protocol-dependent: Influence of non-motor factors on locomotor function
    • Pallier PN, Drew CJ, Morton AJ. The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington's disease are task- and protocol-dependent: Influence of non-motor factors on locomotor function. Brain Res Bull 2009; 78: 347-55.
    • (2009) Brain Res Bull , vol.78 , pp. 347-355
    • Pallier, P.N.1    Drew, C.J.2    Morton, A.J.3
  • 43
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • DOI 10.1006/exnr.1999.7118
    • Popovich PG, Guan Z, Wei P, Huitinga I, van Rooijen N, Stokes BT. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 1999; 158: 351-65. (Pubitemid 29382826)
    • (1999) Experimental Neurology , vol.158 , Issue.2 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van Rooijen, N.5    Stokes, B.T.6
  • 44
    • 0031013236 scopus 로고    scopus 로고
    • Cellular inflammatory response after spinal cord injury in Sprague-Dawley and lewis rats
    • DOI 10.10 02/(SIC I)1096-9861(19 970120)377:3<4 43::AID-CN E10>3.0.CO;2-S
    • Popovich PG, Wei P, Stokes BT. Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 1997; 377: 443-64. (Pubitemid 27016650)
    • (1997) Journal of Comparative Neurology , vol.377 , Issue.3 , pp. 443-464
    • Popovich, P.G.1    Wei, P.2    Stokes, B.T.3
  • 46
    • 40949140945 scopus 로고    scopus 로고
    • Model of acute injury to study neuroprotection
    • Schwartz M, Kipnis J. Model of acute injury to study neuroprotection. Methods Mol Biol 2007; 399: 41-53.
    • (2007) Methods Mol Biol , vol.399 , pp. 41-53
    • Schwartz, M.1    Kipnis, J.2
  • 47
    • 0031738941 scopus 로고    scopus 로고
    • TNF-α and IFN-γ render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL
    • Spanaus KS, Schlapbach R, Fontana A. TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. Eur J Immunol 1998; 28: 4398-408. (Pubitemid 28558671)
    • (1998) European Journal of Immunology , vol.28 , Issue.12 , pp. 4398-4408
    • Spanaus, K.S.1    Schlapbach, R.2    Fontana, A.3
  • 48
    • 0032790541 scopus 로고    scopus 로고
    • Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
    • DOI 10.1038/11387
    • Springer JE, Azbill RD, Knapp PE. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 1999; 5: 943-6. (Pubitemid 29372423)
    • (1999) Nature Medicine , vol.5 , Issue.8 , pp. 943-946
    • Springer, J.E.1    Azbill, R.D.2    Knapp, P.E.3
  • 49
    • 0028525641 scopus 로고
    • Cervical spondylotic myelopathy: A cause of gait disturbance and falls in the elderly
    • 229
    • Swagerty DL Jr. Cervical spondylotic myelopathy: A cause of gait disturbance and falls in the elderly. Kans Med 1994; 95: 226-7, 229.
    • (1994) Kans Med , vol.95 , pp. 226-227
    • Swagerty Jr., D.L.1
  • 50
    • 0031761570 scopus 로고    scopus 로고
    • Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twyl: Morphological changes in anterior horn cells and immunoreactivity to neurotropic factors
    • DOI 10.1007/s004150050287
    • Uchida K, Baba H, Maezawa Y, Furukawa S, Furusawa N, Imura S. Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twy): Morphological changes in anterior horn cells and immunoreactivity to neurotropic factors. J Neurol 1998; 245: 781-93. (Pubitemid 28505273)
    • (1998) Journal of Neurology , vol.245 , Issue.12 , pp. 781-793
    • Uchida, K.1    Baba, H.2    Maezawa, Y.3    Furukawa, S.4    Furusawa, N.5    Imura, S.6
  • 51
    • 0036119784 scopus 로고    scopus 로고
    • Mechanism of destructive pathologic changes in the spinal cord under chronic mechanical compression
    • DOI 10.1097/00007632-200201010-00008
    • Yamaura I, Yone K, Nakahara S, Nagamine T, Baba H, Uchida K, et al. Mechanism of destructive pathologic changes in the spinal cord under chronic mechanical compression. Spine 2002; 27: 21-6. (Pubitemid 34219521)
    • (2002) Spine , vol.27 , Issue.1 , pp. 21-26
    • Yamaura, I.1    Yone, K.2    Nakahara, S.3    Nagamine, T.4    Baba, H.5    Uchida, K.6    Komiya, S.7
  • 53
    • 58249118699 scopus 로고    scopus 로고
    • Molecular mechanisms of spinal cord dysfunction and cell death in the spinal hyperostotic mouse: Implications for the pathophysiology of human cervical spondylotic myelopathy
    • Yu WR, Baptiste DC, Liu T, Odrobina E, Stanisz GJ, Fehlings MG. Molecular mechanisms of spinal cord dysfunction and cell death in the spinal hyperostotic mouse: Implications for the pathophysiology of human cervical spondylotic myelopathy. Neurobiol Dis 2009a; 33: 149-63.
    • (2009) Neurobiol Dis , vol.33 , pp. 149-163
    • Yu, W.R.1    Baptiste, D.C.2    Liu, T.3    Odrobina, E.4    Stanisz, G.J.5    Fehlings, M.G.6
  • 54
    • 58149119499 scopus 로고    scopus 로고
    • Involvement of mitochondrial signaling pathways in the mechanism of Fas-mediated apoptosis after spinal cord injury
    • Yu WR, Liu T, Fehlings TK, Fehlings MG. Involvement of mitochondrial signaling pathways in the mechanism of Fas-mediated apoptosis after spinal cord injury. Eur J Neurosci 2009b; 29: 114-31.
    • (2009) Eur J Neurosci , vol.29 , pp. 114-131
    • Yu, W.R.1    Liu, T.2    Fehlings, T.K.3    Fehlings, M.G.4
  • 55
    • 0034859712 scopus 로고    scopus 로고
    • Presence and significance of CD-95 (Fas/APO1) expression after spinal cord injury
    • Zurita M, Vaquero J, Zurita I. Presence and significance of CD-95 (Fas/APO1) expression after spinal cord injury. J Neurosurg 2001; 94: 257-64. (Pubitemid 32786053)
    • (2001) Journal of Neurosurgery , vol.94 , Issue.2 SUPPL. , pp. 257-264
    • Zurita, M.1    Vaquero, J.2    Zurita, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.