Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion

Nucleic Acids Research

Volumn 39, Issue 16, 2011, Pages 7336-7347

  Wang, Harris H ^a,b   Xu, George ^a,b,c   Vonner, Ashley J ^b   Church, George ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' FLUOROURIDINE; 2,6 DIAMINOPURINE; 5 METHYLDEOXYCYTIDINE; ADENOSINE; CYTIDINE; DEOXYGUANOSINE DERIVATIVE; FLUOROURIDINE; GUANOSINE; ISODEOXYGUANOSINE; NUCLEASE; OLIGONUCLEOTIDE; PROTEIN MUTS; THYMIDINE; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE TARGETING; GENETIC ENGINEERING; GENOMICS; HIGH THROUGHPUT SEQUENCING; MISMATCH REPAIR; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; TERMINAL SEQUENCE;

ALLELES; DNA MISMATCH REPAIR; ESCHERICHIA COLI PROTEINS; GENETIC ENGINEERING; MUTS DNA MISMATCH-BINDING PROTEIN; OLIGONUCLEOTIDES;

ESCHERICHIA COLI;

EID: 79957439984     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr183     Document Type: Article

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