MutS interaction with mismatch and alkylated base containing DNA molecules detected by optical biosensor

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 372, Issue 1, 1996, Pages 87-96

  Babic, Ivan ^a   Andrew, Susan E ^a   Jirik, Frank R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alkylated base; DNA mismatch; MutS; Optical biosensor

Indexed keywords

OLIGONUCLEOTIDE;

ARTICLE; BASE MISPAIRING; BIOSENSOR; DISSOCIATION; DNA BINDING; DNA FOOTPRINTING; DNA REPAIR; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ALKYLATION; BACTERIAL PROTEINS; BASE COMPOSITION; BIOSENSING TECHNIQUES; DEOXYADENINE NUCLEOTIDES; DEOXYGUANINE NUCLEOTIDES; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; ESCHERICHIA COLI PROTEINS; MUTS DNA MISMATCH-BINDING PROTEIN; NUCLEIC ACID HETERODUPLEXES; OLIGONUCLEOTIDES; RECOMBINANT PROTEINS;

EID: 0030580211     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(96)00170-4     Document Type: Article

References (17)

1. Au, K.G., M. Cabrera, J.H, Miller and P. Modrich (1988) Escherichia coli mutY gene product is required for specific A · G-C · G mismatch correction. Proc. Natl. Acad. Sci. USA, 85, 9163-9166.
2. Au, K.G., K. Welsh and P. Modrich (1992) Initiation of methyl-directed mismatch repair. J. Biol. Chem., 267, 12142-12148.
3. Dohet, C., R. Wagner and M. Radman (1985) Repair of defined single base-pair mismatches in Escherichia coli. Proc. Natl. Acad. Sci. USA, 82, 503-505.
4. Ellis, L.A., G.R. Taylor, R. Banks and S. Baumberg (1994) MutS binding protects heteroduplex DNA from exonuclease digestion in vitro: a simple method for detecting mutations. Nucleic Acids Res., 22, 2710-2711.
5. Fersht, A.R. and J.W. Knill-Jones (1981) DNA polymerase accuracy and spontaneous mutation rates: Frequencies of purine · purine, purine · pyrimidine, and pyrimidine · pyrimidine mismatches during DNA replication. Proc. Natl. Acad. Sci. USA, 78, 4251-4255.
6. Jiricny, J., S.-S. Su, S.G. Wood and P. Modrich (1988) Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. Nucleic Acids Res., 16, 7843-7853.
7. Jones, M., R. Wagner and M. Radman (1987) Repair of a mismatch is influenced by the base composition of the surrounding nucleotide sequence. Genetics, 115, 605-610.
8. Kramer, B., W. Kramer and H.-J. Fritz (1984) Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coli. Cell, 38, 879-887.
9. Lahue, R.S., K.G. Au and P. Modrich (1989) DNA mismatch correction in a defined system. Science, 245, 160-164.
10. Learn, B.A. and R.H. Grafstrom (1989) Methyl-directed repair of frameshift heteroduplexes in cell extracts from Escherichia coll. J. Bacteriol., 171, 6473-6481.
11. Lishanski, A., E.A. Ostrander and J Rine (1994) Mutation detection by mismatch binding protein, MutS, in amplified DNA: application to the cystic fibrosis gene. Proc. Natl. Acad. Sci. USA, 91, 2674-2678.
12. Parker, B.O. and M.G. Marinus (1992) Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli. Proc. Natl. Acad. Sci. USA, 89, 1730-1734.
13. 6-ethenoadenine when present in DNA. Nucleic Acids Res., 23, 3750-3755.
14. Su, S.-S. and P. Modrich (1986) Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proc. Natl. Acad. Sci. USA, 83, 5057-5061.
15. Su, S.-S., R.S. Lahue, K.G. Au and P. Modrich (1988) Mispair specificity of methyl-directed DNA mismatch correction in vitro. J. Biol. Chem., 263, 6829-6835.
16. 4-alkylthymidine and the mutagenic properties of these bases. Mutation Res., 233, 81-94.
17. Wagner, R., P. Debbie and M. Radman (1995) Mutation detection using immobilized mismatch binding protein (MutS). Nucleic Acids Res., 23, 3944-3948.