-
1
-
-
2442521050
-
Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds
-
Yun TK, Lee YS, Lee YH, Kim SI, Yun HY (2001) Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds. J Korean Med Sci 16:6-18
-
(2001)
J Korean Med Sci
, vol.16
, pp. 6-18
-
-
Yun, T.K.1
Lee, Y.S.2
Lee, Y.H.3
Kim, S.I.4
Yun, H.Y.5
-
2
-
-
37549015237
-
2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia
-
DOI 10.1016/j.jep.2007.10.026, PII S0378874107005454
-
Zhang G, Liu A, Zhou Y, San X, Jin T, Jin Y (2008) Panax ginseng ginsenoside-Rg2 protects memory impairment via antiapoptosis in a rat model with vascular dementia. J Ethnopharmacol 115:441-448 (Pubitemid 50017508)
-
(2007)
Journal of Ethnopharmacology
, vol.115
, Issue.3
, pp. 441-448
-
-
Zhang, G.1
Liu, A.2
Zhou, Y.3
San, X.4
Jin, T.5
Jin, Y.6
-
3
-
-
59449090299
-
Antiobesity effects of wild ginseng (Panax ginseng C.A. Meyer) mediated by PPAR-γ, GLUT4 and LPL in ob/ob mice
-
Mollah ML, Kim GS, Moon HK, Chung SK, Cheon YP, Kim JK, Kim KS (2009) Antiobesity effects of wild ginseng (Panax ginseng C.A. Meyer) mediated by PPAR-γ, GLUT4 and LPL in ob/ob mice. Phytother Res 23:220-225
-
(2009)
Phytother Res
, vol.23
, pp. 220-225
-
-
Mollah, M.L.1
Kim, G.S.2
Moon, H.K.3
Chung, S.K.4
Cheon, Y.P.5
Kim, J.K.6
Kim, K.S.7
-
4
-
-
70349571741
-
Anti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage
-
Park BJ, Lim YS, Lee HJ, Eum WS, Park J, Han KH, Choi SY, Lee KS (2009) Anti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage. BMB Rep 42:500-505
-
(2009)
BMB Rep
, vol.42
, pp. 500-505
-
-
Park, B.J.1
Lim, Y.S.2
Lee, H.J.3
Eum, W.S.4
Park, J.5
Han, K.H.6
Choi, S.Y.7
Lee, K.S.8
-
5
-
-
33746080868
-
Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice
-
DOI 10.1038/sj.bjp.0706794, PII 0706794
-
Kimura Y, Sumiyoshi M, Kawahira K, Sakanaka M (2006) Effect of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice. Br J Pharmacol 148:860-870 (Pubitemid 44079416)
-
(2006)
British Journal of Pharmacology
, vol.148
, Issue.6
, pp. 860-870
-
-
Kimura, Y.1
Sumiyoshi, M.2
Kawahira, K.3
Sakanaka, M.4
-
6
-
-
0034075605
-
The cancer-preventive potential of Panax ginseng
-
Shin HR, Kim JY, Yun TK, Morgan G, Vainio H (2000) The cancer-preventive potential of Panax ginseng. Cancer Cause Control 11:565-576
-
(2000)
Cancer Cause Control
, vol.11
, pp. 565-576
-
-
Shin, H.R.1
Kim, J.Y.2
Yun, T.K.3
Morgan, G.4
Vainio, H.5
-
7
-
-
0035653529
-
Chemistry and cancer preventing activities of Ginseng saponins and some related triterpenoid compounds
-
Shibata S (2001) Chemistry and cancer preventing activities of Ginseng saponins and some related triterpenoid compounds. J Korean Med Sci 16:28-37
-
(2001)
J Korean Med Sci
, vol.16
, pp. 28-37
-
-
Shibata, S.1
-
8
-
-
0029034101
-
Preventive effect of ginseng intake against various human cancers: A case-control study on 1987 pairs
-
Yun TK, Choi SY (1995) Preventive effect of ginseng intake against various human cancers: a case-control study on 1987 pairs. Cancer Epidemiol Biomarkers Prev 4:401-408
-
(1995)
Cancer Epidemiol Biomarkers Prev
, vol.4
, pp. 401-408
-
-
Yun, T.K.1
Choi, S.Y.2
-
9
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL (2002) Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2:38-47 (Pubitemid 37328806)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
11
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270:1230-1237
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
13
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1α
-
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L (1998) Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha. EMBO J 17:6573-6586 (Pubitemid 28521792)
-
(1998)
EMBO Journal
, vol.17
, Issue.22
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'Brien, S.3
Carrero, P.4
Makino, Y.5
Tanaka, H.6
Poellinger, L.7
-
14
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
-
Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL (2000) The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 157:411-421 (Pubitemid 30626905)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
15
-
-
0033870727
-
Hypoxia-inducible factor-1α is a positive factor in solid tumor growth
-
Ryan HE, Poloni M, McNulty W, Elson D, Gassmann M, Arbeit JM, Johnson RS (2000) Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. Cancer Res 60:4010-4015 (Pubitemid 30636574)
-
(2000)
Cancer Research
, vol.60
, Issue.15
, pp. 4010-4015
-
-
Ryan, H.E.1
Poloni, M.2
McNulty, W.3
Elson, D.4
Gassmann, M.5
Arbeit, J.M.6
Johnson, R.S.7
-
16
-
-
0035205085
-
A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses
-
Chun YS, Choi E, Yeo YJ, Lee JH, Kim MS, Park JW (2001) A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1- mediated hypoxic response. J Cell Sci 114:4051-4061 (Pubitemid 33115026)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.22
, pp. 4051-4061
-
-
Chun, Y.-S.1
Choi, E.2
Yeo, E.-J.3
Lee, J.H.4
Kim, M.-S.5
Park, J.-W.6
-
17
-
-
0033928280
-
Erythroid progenitors differentiate and mature in response to endogenous erythropoietin
-
Sato T, Maekawa T, Watanabe S, Tsuji K, Nakahata T (2000) Erythroid progenitors differentiate and mature in response to endogenous erythropoietin. J Clin Invest 106:263-270 (Pubitemid 30483130)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.2
, pp. 263-270
-
-
Sato, T.1
Maekawa, T.2
Watanabe, S.3
Tsuji, K.4
Nakahata, T.5
-
18
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ (2006) Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440:1222-1226
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
Chi, J.T.7
Jeffrey, S.S.8
Giaccia, A.J.9
-
19
-
-
33644614520
-
HIF-1- mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV (2006) HIF-1- mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3:177-185
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
20
-
-
58149102376
-
Current insights on the biology and clinical aspects of VEGF regulation
-
Birk DM, Barbato J, Mureebe L, Chaer RA (2008) Current insights on the biology and clinical aspects of VEGF regulation. Vasc Endovasc Surg 42:517-530
-
(2008)
Vasc Endovasc Surg
, vol.42
, pp. 517-530
-
-
Birk, D.M.1
Barbato, J.2
Mureebe, L.3
Chaer, R.A.4
-
21
-
-
33846013596
-
Ginsenoside-Rg1 induces vascular endothelial growth factor expression through the glucocorticoid receptor-related phosphatidylinositol 3-kinase/Akt and β-catenin/T-cell factor-dependent pathway in human endothelial cells
-
DOI 10.1074/jbc.M606698200
-
Leung KW, Pon YL, Wong RN, Wong AS (2006) Ginsenoside- Rg1 induces vascular endothelial growth factor expression through the glucocorticoid receptor-related phosphatidylinositol 3-kinase/Akt and β-catenin/T-cell factor-dependent pathway in human endothelial cells. J Biol Chem 47:36280-36288 (Pubitemid 46041363)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.47
, pp. 36280-36288
-
-
Kar, W.L.1
Yuen, L.P.2
Wong, R.N.S.3
Wong, A.S.T.4
-
22
-
-
34347339390
-
L
-
DOI 10.1089/neu.2006.0182
-
Sakanaka M, Zhu P, Zhang B, Wen TC, Cao F, Ma YJ, Samukawa K, Mitsuda N, Tanaka J, Kuramoto M, Uno H, Hata R (2007) Intravenous infusion of dihydroginsenoside Rb1 prevents compressive spinal cord injury and ischemic brain damage through upregulation of VEGF and Bcl-xL. J Neurotrauma 24:1037-1054 (Pubitemid 47015437)
-
(2007)
Journal of Neurotrauma
, vol.24
, Issue.6
, pp. 1037-1054
-
-
Sakanaka, M.1
Zhu, P.2
Zhang, B.3
Wen, T.-C.4
Cao, F.5
Ma, Y.-J.6
Samukawa, K.7
Mitsuda, N.8
Tanaka, J.9
Kuramoto, M.10
Uno, H.11
Hata, R.12
-
23
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
DOI 10.1016/S0092-8674(01)00507-4
-
Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ (2001) C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107:43-54 (Pubitemid 32972036)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.-M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
24
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 292:468-472 (Pubitemid 32335942)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
25
-
-
58149374576
-
Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth
-
ZhangH,QianDZ, TanYS, LeeK,Gao P, RenYR, Rey S,Hammers H, Chang D, Pili R, Dang CV, Liu JO Semenza GL (2008) Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci USA 105:19579-19586
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19579-19586
-
-
Zhang, H.1
Qian, D.Z.2
Tan, Y.S.3
Lee, K.4
Gao, P.5
Ren, Y.R.6
Rey, S.7
Hammers, H.8
Chang, D.9
Pili, R.10
Dang, C.V.11
Liu, J.O.12
Semenza, G.L.13
-
26
-
-
20144387547
-
Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1α
-
DOI 10.1158/0008-5472.CAN-03-2735
-
Bae MK, Jeong JW, Kim SH, Kim SY, Kang HJ, Kim DM, Bae SK, Yun I, Trentin GA, Rozakis-Adcock M, Kim KW (2005) Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1alpha. Cancer Res 65:2520-2525 (Pubitemid 40490044)
-
(2005)
Cancer Research
, vol.65
, Issue.7
, pp. 2520-2525
-
-
Bae, M.-K.1
Jeong, J.-W.2
Kim, S.-H.3
Kim, S.-Y.4
Hye, J.K.5
Kim, D.-M.6
Bae, S.-K.7
Yun, I.8
Trentin, G.A.9
Rozakis-Adcock, M.10
Kim, K.-W.11
-
27
-
-
38349019701
-
Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells
-
Staab A, Loeffler J, Said HM, Diehlmann D, Katzer A, Beyer M, Fleischer M, Schwab F, Baier K, Einsele H, Flentje M, Vordermark D (2007) Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells. BMC Cancer 7:213
-
(2007)
BMC Cancer
, vol.7
, pp. 213
-
-
Staab, A.1
Loeffler, J.2
Said, H.M.3
Diehlmann, D.4
Katzer, A.5
Beyer, M.6
Fleischer, M.7
Schwab, F.8
Baier, K.9
Einsele, H.10
Flentje, M.11
Vordermark, D.12
-
28
-
-
25444523184
-
Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity
-
DOI 10.1158/0008-5472.CAN-05-1235
-
Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH, Melillo G (2005) Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNAbinding activity. Cancer Res 65:9047-9055 (Pubitemid 41377397)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 9047-9055
-
-
Kong, D.1
Park, E.J.2
Stephen, A.G.3
Calvani, M.4
Cardellina, J.H.5
Monks, A.6
Fisher, R.J.7
Shoemaker, R.H.8
Melillo, G.9
-
29
-
-
70449580319
-
Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
-
Lee K, Zhang H, Qian DZ, Rey S, Liu JO, Semenza GL (2009) Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization. Proc Natl Acad Sci USA 106:17910-17915
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17910-17915
-
-
Lee, K.1
Zhang, H.2
Qian, D.Z.3
Rey, S.4
Liu, J.O.5
Semenza, G.L.6
-
30
-
-
69849086292
-
Effect of gensenoside Rg3 on apoptosis of Hep-2 and expression of HIF-1alpha in human laryngeal cancer cell line under anoxic conditions
-
Wang BS, Zhang LS, Song DM, Zhang JH, Liu YM (2009) Effect of gensenoside Rg3 on apoptosis of Hep-2 and expression of HIF-1alpha in human laryngeal cancer cell line under anoxic conditions. Zhong Yao Cai 32:102-106
-
(2009)
Zhong Yao Cai
, vol.32
, pp. 102-106
-
-
Wang, B.S.1
Zhang, L.S.2
Song, D.M.3
Zhang, J.H.4
Liu, Y.M.5
|