-
1
-
-
79956202862
-
-
Alzheimers Disease Education and Referral (ADEAR) Center. A Service of the National Institute on Aging. Alzheimers Disease Fact Sheet MD, USA
-
Alzheimers Disease Education and Referral (ADEAR) Center. A Service of the National Institute on Aging. Alzheimers Disease Fact Sheet. NIH Publication No.: 08-6423, MD, USA (2010).
-
(2010)
NIH Publication 08-6423
-
-
-
2
-
-
75449102536
-
Mechanisms of disease Alzheimers disease
-
Querfurth HW, La Ferla FM. Mechanisms of disease Alzheimers disease. N. Engl. J. Med. 362(4), 329-344 (2010).
-
(2010)
N. Engl. J. Med.
, vol.36
, Issue.4
, pp. 329-344
-
-
Querfurth, H.W.1
La Ferla, F.M.2
-
3
-
-
65249184946
-
Current concepts in Alzheimers disease: A multidisciplinary review
-
Minati L, Edginton T, Bruzzone MG, Giaccone G. Current concepts in Alzheimers disease: a multidisciplinary review. Am. J. Alzheimers Dis. 24(2), 95-121 (2009).
-
(2009)
Am. J. Alzheimers Dis.
, vol.24
, Issue.2
, pp. 95-121
-
-
Minati, L.1
Edginton, T.2
Bruzzone, M.G.3
Giaccone, G.4
-
4
-
-
29144508843
-
Global prevalence of dementia: A Delphi consensus study
-
DOI 10.1016/S0140-6736(05)67889-0, PII S0140673605678890
-
Ferri CP, Prince M, Brayne C, et al. Global prevalence of dementia: a Delphi consensus study. Lancet 366(9503), 2112-2117 (2005). (Pubitemid 41797645)
-
(2005)
Lancet
, vol.366
, Issue.9503
, pp. 2112-2117
-
-
Ferri, C.P.1
Prince, M.2
Brayne, C.3
Brodaty, H.4
Fratiglioni, L.5
Ganguli, M.6
Hall, K.7
Hasegawa, K.8
Hendrie, H.9
Huang, Y.10
Jorm, A.11
Mathers, C.12
Menezes, P.R.13
Rimmer, E.14
Scazufca, M.15
-
5
-
-
0016823810
-
Mini-mental state - Practical method for grading cognitive state of patients for clinician
-
Folstein MF, Folstein SE, Mchugh PR. Mini-mental state - practical method for grading cognitive state of patients for clinician. J. Psychiatr. Res. 12(3), 189-198 (1975).
-
(1975)
J. Psychiatr. Res.
, vol.12
, Issue.3
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
6
-
-
0037344642
-
Long-term cognitive and functional decline in late onset Alzheimer's disease: Therapeutic implications
-
DOI 10.1093/ageing/32.2.200
-
Holmes C, Lovestone S. Long-term cognitive and functional decline in late onset Alzheimers disease: therapeutic implications. Age Ageing 32(2), 200-204 (2003). (Pubitemid 36372428)
-
(2003)
Age and Ageing
, vol.32
, Issue.2
, pp. 200-204
-
-
Holmes, C.1
Lovestone, S.2
-
7
-
-
1942470073
-
Metabolomics by numbers: Acquiring and understanding global metabolite data
-
DOI 10.1016/j.tibtech.2004.03.007, PII S0167779904000812
-
Goodacre R, Vaidyanathan S, Dunn WB, Harrigan GG, Kell DB. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends Biotechnol. 22(5), 245-252 (2004). (Pubitemid 38515742)
-
(2004)
Trends in Biotechnology
, vol.22
, Issue.5
, pp. 245-252
-
-
Goodacre, R.1
Vaidyanathan, S.2
Dunn, W.B.3
Harrigan, G.G.4
Kell, D.B.5
-
8
-
-
0242607632
-
Parallel analysis of transcript and metabolic profiles: A new approch in systems biology
-
DOI 10.1038/sj.embor.embor944
-
Urbanczyk-Wochniak E, Luedemann A, Kopka J, et al. Parallel analysis of transcript and metabolic profiles: a new approach in systems biology. EMBO Rep. 4(10), 989-993 (2003). (Pubitemid 37407468)
-
(2003)
EMBO Reports
, vol.4
, Issue.10
, pp. 989-993
-
-
Urbanczyk-Wochniak, E.1
Leudemann, A.2
Kopka, J.3
Selbig, J.4
Roessner-Tunali, U.5
Willmitzer, L.6
Fernie, A.R.7
-
9
-
-
33749245441
-
Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: A nonrandomised controlled trial with magnetic resonance spectroscopy
-
DOI 10.2165/00023210-200620100-00006
-
Modrego PJ, Pina MA, Fayed N, Diaz M. Changes in metabolite ratios after treatment with rivastigmine in Alzheimers disease - a nonrandomised controlled trial with magnetic resonance spectroscopy. CNS Drugs 20(10), 867-877 (2006). (Pubitemid 44484248)
-
(2006)
CNS Drugs
, vol.20
, Issue.10
, pp. 867-877
-
-
Modrego, P.J.1
Pina, M.A.2
Fayed, N.3
Diaz, M.4
-
10
-
-
73649110564
-
Increased glutamate in the hippocampus after galantamine treatment for Alzheimers disease
-
Penner J, Rupsingh R, Smith M, Wells JL, Borrie MJ, Bartha R. Increased glutamate in the hippocampus after galantamine treatment for Alzheimers disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(1), 104-110 (2010).
-
(2010)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.34
, Issue.1
, pp. 104-110
-
-
Penner, J.1
Rupsingh, R.2
Smith, M.3
Wells, J.L.4
Borrie, M.J.5
Bartha, R.6
-
11
-
-
0032514128
-
Levels of tau phosphorylation at different sites in Alzheimer disease brain
-
Ikura Y, Kudo T, Tanaka T, et al. Levels of tau phosphorylation at different sites in Alzheimer disease brain. Neuroreport 9(10), 2375-2379 (1998). (Pubitemid 28338237)
-
(1998)
NeuroReport
, vol.9
, Issue.10
, pp. 2375-2379
-
-
Ikura, Y.1
Kudo, T.2
Tanaka, T.3
Tanii, H.4
Grundke-Iqbal, I.5
Iqbal, K.6
Takeda, M.7
-
12
-
-
0032586942
-
4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease
-
DOI 10.1046/j.1471-4159.1999.0720734.x
-
Nourooz-Zadeh J, Liu EHC, Yhlen B, Anggard EE, Halliwell B. F-4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimers disease. J. Neurochem. 72(2), 734-740 (1999). (Pubitemid 29055237)
-
(1999)
Journal of Neurochemistry
, vol.72
, Issue.2
, pp. 734-740
-
-
Nourooz-Zadeh, J.1
Liu, E.H.C.2
Yhlen, B.3
Anggard, E.E.4
Halliwell, B.5
-
13
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
DOI 10.1016/S0197-4580(00)00235-9, PII S0197458000002359
-
Lovell MA, Xie CS, Markesbery WR. Acrolein is increased in Alzheimers disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging 22(2), 187-194 (2001). (Pubitemid 32162967)
-
(2001)
Neurobiology of Aging
, vol.22
, Issue.2
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
14
-
-
0030926085
-
Proton magnetic resonance spectroscopy can differentiate Alzheimer's disease from normal aging
-
DOI 10.1016/S0047-6374(97)01877-0, PII S0047637497018770
-
Parnetti L, Tarducci R, Presciutti O, et al. Proton magnetic resonance spectroscopy can differentiate Alzheimers disease from normal aging. Mech. Ageing Dev. 97(1), 9-14 (1997). (Pubitemid 27279860)
-
(1997)
Mechanisms of Ageing and Development
, vol.97
, Issue.1
, pp. 9-14
-
-
Parnetti, L.1
Tarducci, R.2
Presciutti, O.3
Lowenthal, D.T.4
Pippi, M.5
Palumbo, B.6
Gobbi, G.7
Pelliccioli, G.P.8
Senin, U.9
-
15
-
-
0034484915
-
Magnetic resonance spectroscopy in Alzheimer's disease: Focus on N-acetylaspartate
-
Chen JG, Charles HC, Barboriak DP, Doraiswamy PM. Magnetic resonance spectroscopy in Alzheimers disease: focus on N-acetylaspartate. Acta Neurologica Scandinavica 102, 20-26 (2000). (Pubitemid 32156166)
-
(2000)
Acta Neurologica Scandinavica, Supplement
, vol.102
, Issue.176
, pp. 20-26
-
-
Chen, J.G.1
Charles, H.C.2
Barboriak, D.3
Doraiswamy, P.M.4
-
16
-
-
47949105879
-
Magnetic resonance spectroscopy performance for detection of dementia, Alzheimers disease and mild cognitive impairment in a community-based survey
-
Santos JMG, Gavrila D, Antunez C, et al. Magnetic resonance spectroscopy performance for detection of dementia, Alzheimers disease and mild cognitive impairment in a community-based survey. Dement. Geriatr. Cogn. 26(1), 15-25 (2008).
-
(2008)
Dement. Geriatr. Cogn.
, vol.26
, Issue.1
, pp. 15-25
-
-
Jmg, S.1
Gavrila, D.2
Antunez, C.3
-
17
-
-
33750455449
-
CSF diagnosis of Alzheimer's disease and dementia with Lewy bodies
-
DOI 10.1007/s00702-006-0537-z, 100 Years of Alzheimer's Disease
-
Bibl M, Mollenhauer B, Esselmann H, et al. CSF diagnosis of Alzheimers disease and dementia with Lewy bodies. J. Neural Transm. 113(11), 1771-1778 (2006). (Pubitemid 44657673)
-
(2006)
Journal of Neural Transmission
, vol.113
, Issue.11
, pp. 1771-1778
-
-
Bibl, M.1
Mollenhauer, B.2
Esselmann, H.3
Lewczuk, P.4
Trenkwalder, C.5
Brechlin, P.6
Ruther, E.7
Kornhuber, J.8
Otto, M.9
Wiltfang, J.10
-
18
-
-
0041358773
-
A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease
-
DOI 10.1002/pmic.200300470
-
Carrette O, Demalte I, Scherl A, et al. A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimers disease. Proteomics 3(8), 1486-1494 (2003). (Pubitemid 37048074)
-
(2003)
Proteomics
, vol.3
, Issue.8
, pp. 1486-1494
-
-
Carrette, O.1
Demalte, I.2
Scherl, A.3
Yalkinoglu, O.4
Corthals, G.5
Burkhard, P.6
Hochstrasser, D.F.7
Sanchez, J.-C.8
-
19
-
-
44949219321
-
Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia
-
DOI 10.1016/j.neurobiolaging.2007.02.016, PII S0197458007000553
-
Engelborghs S, De Vreese K, Van de Casteele T, et al. Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia. Neurobiol. Aging 29(8), 1143-1159 (2008). (Pubitemid 351822410)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.8
, pp. 1143-1159
-
-
Engelborghs, S.1
De Vreese, K.2
Van De Casteele, T.3
Vanderstichele, H.4
Van Everbroeck, B.5
Cras, P.6
Martin, J.-J.7
Vanmechelen, E.8
De Deyn, P.P.9
-
20
-
-
29244490349
-
Identification of disease markers in human cerebrospinal fluid using lipidomic and proteomic methods
-
Fonteh AN, Harrington RJ, Huhmer AF, Biringer RG, Riggins JN, Harrington MG. Identification of disease markers in human cerebrospinal fluid using lipidomic and proteomic methods. Dis. Markers 22(1-2), 39-64 (2006). (Pubitemid 41831604)
-
(2006)
Disease Markers
, vol.22
, Issue.1-2
, pp. 39-64
-
-
Fonteh, A.N.1
Harrington, R.J.2
Huhmer, A.F.3
Biringer, R.G.4
Riggins, J.N.5
Harrington, M.G.6
-
21
-
-
0034899223
-
Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease
-
DOI 10.1002/ana.1054
-
Itoh N, Arai H, Urakami K, et al. Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimers disease. Ann. Neurol. 50(2), 150-156 (2001). (Pubitemid 32738138)
-
(2001)
Annals of Neurology
, vol.50
, Issue.2
, pp. 150-156
-
-
Itoh, N.1
Arai, H.2
Urakami, K.3
Ishiguro, K.4
Ohno, H.5
Hampel, H.6
Buerger, K.7
Wiltfang, J.8
Otto, M.9
Kretzschmar, H.10
Moeller, H.-J.11
Imagawa, M.12
Kohno, H.13
Nakashima, K.14
Kuzuhara, S.15
Sasaki, H.16
Imahori, K.17
-
22
-
-
77951156488
-
Cerebrospinal fluid steroidomics: Are bioactive bile acids present in brain?
-
Ogundare M, Theofilopoulos S, Lockhart A, et al. Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J. Biol. Chem. 285(7), 4666-4679 (2009).
-
(2009)
J. Biol. Chem.
, vol.285
, Issue.7
, pp. 4666-4679
-
-
Ogundare, M.1
Theofilopoulos, S.2
Lockhart, A.3
-
23
-
-
21844437399
-
Study of plasma antioxidant status in Alzheimer's disease
-
DOI 10.1111/j.1468-1331.2005.01000.x
-
Pulido R, Jimenez-Escrig A, Orensanz L, Saura-Calixto F. Study of plasma antioxidant status in Alzheimers disease. Eur. J. Neurol. 12(7), 531-535 (2005). (Pubitemid 40956810)
-
(2005)
European Journal of Neurology
, vol.12
, Issue.7
, pp. 531-535
-
-
Pulido, R.1
Jimenez-Escrig, A.2
Orensanz, L.3
Saura-Calixto, F.4
Jimenez-Escrig, A.5
-
24
-
-
41749092079
-
Plasma biomarkers of Alzheimers disease
-
Kawarabayashi T, Shoji M. Plasma biomarkers of Alzheimers disease. Curr. Opin. Psychiatry 21(3), 260-267 (2008).
-
(2008)
Curr. Opin. Psychiatry
, vol.21
, Issue.3
, pp. 260-267
-
-
Kawarabayashi, T.1
Shoji, M.2
-
25
-
-
33750596715
-
Proteome-based plasma biomarkers for Alzheimer's disease
-
DOI 10.1093/brain/awl279
-
Hye A, Lynham S, Thambisetty M, et al. Proteome-based plasma biomarkers for Alzheimers disease. Brain 129(Pt 11), 3042-3050 (2006). (Pubitemid 44684524)
-
(2006)
Brain
, vol.129
, Issue.11
, pp. 3042-3050
-
-
Hye, A.1
Lynham, S.2
Thambisetty, M.3
Causevic, M.4
Campbell, J.5
Byers, H.L.6
Hooper, C.7
Rijsdijk, F.8
Tabrizi, S.J.9
Banner, S.10
Shaw, C.E.11
Foy, C.12
Poppe, M.13
Archer, N.14
Hamilton, G.15
Powell, J.16
Brown, R.G.17
Sham, P.18
Ward, M.19
Lovestone, S.20
more..
-
26
-
-
3242690571
-
2-isoprostanes levels in the patients with Alzheimer's disease
-
DOI 10.1016/j.brainresbull.2004.04.016, PII S0361923004001236
-
Kim KM, Jung BH, Paeng KJ, Kim I, Chung BC. Increased urinary F-2- isoprostanes levels in the patients with Alzheimers disease. Brain Res. Bull. 64(1), 47-51 (2004). (Pubitemid 38953468)
-
(2004)
Brain Research Bulletin
, vol.64
, Issue.1
, pp. 47-51
-
-
Kim, K.M.1
Jung, B.H.2
Paeng, K.-J.3
Kim, I.4
Chung, B.C.5
-
27
-
-
0027493214
-
Increased levels of truncated nerve growth factor receptor in urine of mildly demented patients with Alzheimer's disease
-
Lindner MD, Gordon DD, Miller JM, et al. Increased levels of truncated nerve growth-factor receptor in urine of mildly demented patients with Alzheimers-disease. Arch. Neurol. 50(10), 1054-1058 (1993). (Pubitemid 23301250)
-
(1993)
Archives of Neurology
, vol.50
, Issue.10
, pp. 1054-1058
-
-
Lindner, M.D.1
Gordon, D.D.2
Miller, J.M.3
Tariot, P.N.4
McDaniel, K.D.5
Hamill, R.W.6
DiStefano, P.S.7
Loy, R.8
-
28
-
-
0031711064
-
Biochemical assay for AD7C-NTP in urine as an Alzheimer's disease marker
-
DOI 10.10 02/(SI CI)1098-282 5(1998)12:5<28 5::AID-JCL A6>3.0.CO;2-5
-
Ghanbari H, Ghanbari K, Beheshti I, Munzar M, Vasauskas A, Averback P. Biochemical assay for AD7C-NTP in urine as an Alzheimers disease marker. J. Clin. Lab. Anal. 12(5), 285-288 (1998). (Pubitemid 28462315)
-
(1998)
Journal of Clinical Laboratory Analysis
, vol.12
, Issue.5
, pp. 285-288
-
-
Ghanbari, H.1
Ghanbari, K.2
Beheshti, I.3
Munzar, M.4
Vasauskas, A.5
Averback, P.6
-
29
-
-
34247343262
-
Microvascular injury and blood-brain barrier leakage in Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2006.05.016, PII S0197458006001758
-
Zipser BD, Johanson CE, Gonzalez L, et al. Microvascular injury and blood-brain barrier leakage in Alzheimers disease. Neurobiol. Aging 28(7), 977-986 (2007). (Pubitemid 46635913)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.7
, pp. 977-986
-
-
Zipser, B.D.1
Johanson, C.E.2
Gonzalez, L.3
Berzin, T.M.4
Tavares, R.5
Hulette, C.M.6
Vitek, M.P.7
Hovanesian, V.8
Stopa, E.G.9
-
30
-
-
0033391684
-
The blood-brain barrier and cerebrovascular pathology in Alzheimer's disease
-
Kalaria RN. The blood-brain barrier and cerebrovascular pathology in Alzheimers disease. Ann. NY Acad. Sci. 893, 113-125 (1999). (Pubitemid 30038071)
-
(1999)
Annals of the New York Academy of Sciences
, vol.893
, pp. 113-125
-
-
Kalaria, R.N.1
-
31
-
-
0030662598
-
Vascular basement membrane pathology and Alzheimer's disease
-
DOI 10.1111/j.1749-6632.1997.tb48467.x
-
Zarow C, Barron E, Chui HC, Perlmutter LS. Vascular basement membrane pathology and Alzheimers disease. Ann. NY Acad. Sci. 826, 147-160 (1997). (Pubitemid 27478037)
-
(1997)
Annals of the New York Academy of Sciences
, vol.826
, pp. 147-160
-
-
Zarow, C.1
Barron, E.2
Chui, H.C.3
Perlmutter, L.S.4
-
32
-
-
43349093602
-
Quantification of H-1 NMR spectra of human cerebrospinal fluid: A protocol based on constrained total-line-shape analysis
-
Jukarainen NM, Korhonen SP, Laakso MP, et al. Quantification of H-1 NMR spectra of human cerebrospinal fluid: a protocol based on constrained total-line-shape analysis. Metabolomics 4(2), 150-160 (2008).
-
(2008)
Metabolomics
, vol.4
, Issue.2
, pp. 150-160
-
-
Jukarainen, N.M.1
Korhonen, S.P.2
Laakso, M.P.3
-
33
-
-
24944562078
-
Magnetic resonance spectroscopy
-
DOI 10.1097/01.wno.0000177307.21081.81
-
Gujar SK, Maheshwari S, Bjorkman- Burtscher I, Sundgren PC. Magnetic resonance spectroscopy. J. Neuroophthalmol. 25(3), 217-226 (2005). (Pubitemid 41306683)
-
(2005)
Journal of Neuro-Ophthalmology
, vol.25
, Issue.3
, pp. 217-226
-
-
Gujar, S.K.1
Maheshwari, S.2
Bjorkman-Burtscher, I.3
Sundgren, P.C.4
-
34
-
-
0034849057
-
Brain membrane phospholipid alterations in Alzheimer's disease
-
DOI 10.1023/A:1011603916962
-
Pettegrew JW, Panchalingam K, Hamilton RL, McClure RJ. Brain membrane phospholipid alterations in Alzheimers disease. Neurochem. Res. 26(7), 771-782 (2001). (Pubitemid 32845968)
-
(2001)
Neurochemical Research
, vol.26
, Issue.7
, pp. 771-782
-
-
Pettegrew, J.W.1
Panchalingam, K.2
Hamilton, R.L.3
Mcclure, R.J.4
-
35
-
-
0028978925
-
N-acetylaspartate in neuropsychiatric disorders
-
Tsai G, Coyle JT. N-acetylaspartate in neuropsychiatric disorders. Prog. Neurobiol. 46(5), 531-540 (1995).
-
(1995)
Prog. Neurobiol.
, vol.46
, Issue.5
, pp. 531-540
-
-
Tsai, G.1
Coyle, J.T.2
-
36
-
-
0030974007
-
1H NMR study of the hippocampus and cerebellum
-
Mohanakrishnan P, Fowler AH, Vonsattel JP, et al. Regional metabolic alterations in Alzheimers disease: an in vitro H-1 NMR study of the hippocampus and cerebellum. J. Gerontol. A Biol. Sci. Med. Sci. 52(2), B111-B117 (1997). (Pubitemid 27123961)
-
(1997)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.52
, Issue.2
-
-
Mohanakrishnan, P.1
Fowler, A.H.2
Vonsattel, J.P.3
Jolles, P.R.4
Husain, M.M.5
Liem, P.6
Myers, L.7
Komoroski, R.A.8
-
37
-
-
0028932753
-
Probable Alzheimer-disease - Diagnosis with proton Mr Spectroscopy
-
Shonk TK, Moats RA, Gifford P, et al. Probable Alzheimer-disease - diagnosis with proton Mr Spectroscopy. Radiology 195(1), 65-72 (1995).
-
(1995)
Radiology
, vol.195
, Issue.1
, pp. 65-72
-
-
Shonk, T.K.1
Moats, R.A.2
Gifford, P.3
-
38
-
-
0035964302
-
1H MRS study
-
Huang W, Alexander GE, Chang L, et al. Brain metabolite concentration and dementia severity in Alzheimers disease - a H-1 MRS study. Neurology 57(4), 626-632 (2001). (Pubitemid 32782989)
-
(2001)
Neurology
, vol.57
, Issue.4
, pp. 626-632
-
-
Huang, W.1
Alexander, G.E.2
Chang, L.3
Shetty, H.U.4
Krasuski, J.S.5
Rapoport, S.I.6
Schapiro, M.B.7
-
39
-
-
16444378671
-
1H MR spectroscopy using TE averaged PRESS: A more sensitive technique to detect neurodegeneration associated with Alzheimer's disease
-
DOI 10.1002/mrm.20419
-
Hancu I, Zimmerman EA, Sailasuta N, Hurd RE. H-1 MR spectroscopy using TE averaged PRESS: a more sensitive technique to detect neuro degeneration associated with Alzheimers disease. Magn. Reson. Med. 53(4), 777-782 (2005). (Pubitemid 40478424)
-
(2005)
Magnetic Resonance in Medicine
, vol.53
, Issue.4
, pp. 777-782
-
-
Hancu, I.1
Zimmerman, E.A.2
Sailasuta, N.3
Kurd, R.E.4
-
40
-
-
0033852551
-
1H MRS study
-
Kantarci K, Jack CR, Xu YC, et al. Regional metabolic patterns in mild cognitive impairment and Alzheimers disease - a H-1 MRS study. Neurology 55(2), 210-217 (2000). (Pubitemid 30604620)
-
(2000)
Neurology
, vol.55
, Issue.2
, pp. 210-217
-
-
Kantarci, K.1
Jack Jr., C.R.2
Xu, Y.C.3
Campeau, N.G.4
O'Brien, P.C.5
Smith, G.E.6
Ivnik, R.J.7
Boeve, B.F.8
Kokmen, E.9
Tangalos, E.G.10
Petersen, R.C.11
-
41
-
-
0036091568
-
Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer disease
-
Block W, Jessen F, Traber F, et al. Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer disease. Arch. Neurol. 59(5), 828-834 (2002). (Pubitemid 34517767)
-
(2002)
Archives of Neurology
, vol.59
, Issue.5
, pp. 828-834
-
-
Block, W.1
Jessen, F.2
Traber, F.3
Flacke, S.4
Manka, C.5
Lamerichs, R.6
Keller, E.7
Heun, R.8
Schild, H.9
-
42
-
-
9944222544
-
In vivo proton magnetic resonance spectroscopy of the temporal lobe in Alzheimer's disease
-
DOI 10.1016/j.pnpbp.2004.08.013, PII S0278584604001800
-
Frederick BD, Lyoo IK, Satlin A, et al. In vivo proton magnetic resonance spectroscopy of the temporal lobe in Alzheimers disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 28(8), 1313-1322 (2004). (Pubitemid 39592929)
-
(2004)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.28
, Issue.8
, pp. 1313-1322
-
-
Frederick, B.D.1
Lyoo, I.K.2
Satlin, A.3
Ahn, K.H.4
Kim, M.J.5
Yurgelun-Todd, D.A.6
Cohen, B.M.7
Renshaw, P.F.8
-
43
-
-
47249144768
-
Alzheimer disease: Postmortem neuropathologic correlates of antemortem H-1 MR spectroscopy metabolite measurements
-
Kantarci K, Knopman DS, Dickson DW, et al. Alzheimer disease: postmortem neuropathologic correlates of antemortem H-1 MR spectroscopy metabolite measurements. Radiology 248(1), 210-220 (2008).
-
(2008)
Radiology
, vol.248
, Issue.1
, pp. 210-220
-
-
Kantarci, K.1
Knopman, D.S.2
Dickson, D.W.3
-
44
-
-
0027322890
-
Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy
-
Miller BL, Moats RA, Shonk T, Ernst T, Woolley S, Ross BD. Alzheimer-disease - depiction of increased cerebral myoinositol with proton MR spectroscopy. Radiology 187(2), 433-437 (1993). (Pubitemid 23127850)
-
(1993)
Radiology
, vol.187
, Issue.2
, pp. 433-437
-
-
Miller, B.L.1
Moats, R.A.2
Shonk, T.3
Ernst, T.4
Woolley, S.5
Ross, B.D.6
-
45
-
-
1642336453
-
1H magnetic resonance spectroscopy
-
DOI 10.1046/j.1468-1331.2003.00746.x
-
Martinez-Bisbal MC, Arana E, Marti- Bonmati L, Molla E, Celda B. Cognitive impairment: classification by 1H magnetic resonance spectroscopy. Eur. J. Neurol. 11(3), 187-193 (2004). (Pubitemid 38373034)
-
(2004)
European Journal of Neurology
, vol.11
, Issue.3
, pp. 187-193
-
-
Martinez-Bisbal, M.C.1
Arana, E.2
Marti-Bonmati, L.3
Molla, E.4
Celda, B.5
-
46
-
-
0141653274
-
Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: A bridge to lipidomics
-
DOI 10.1194/jlr.R300004-JLR200
-
Han XL, Gross RW. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics. J. Lipid Res. 44(6), 1071-1079 (2003). (Pubitemid 37279625)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.6
, pp. 1071-1079
-
-
Han, X.1
Gross, R.W.2
-
47
-
-
0033762711
-
Increased 8,12-iso-iPF(2 a)-VI in Alzheimers disease: Correlation of a noninvasive index of lipid peroxidation with disease severity
-
Pratico D, Clark CM, Lee VMY, Trojanowski JQ, Rokach J, FitzGerald GA. Increased 8,12-iso-iPF(2 a)-VI in Alzheimers disease: correlation of a noninvasive index of lipid peroxidation with disease severity. Ann. Neurol. 48(5), 809-812 (2000).
-
(2000)
Ann. Neurol.
, vol.48
, Issue.5
, pp. 809-812
-
-
Pratico, D.1
Clark, C.M.2
Vmy, L.3
Trojanowski, J.Q.4
Rokach, J.5
Fitzgerald, G.A.6
-
48
-
-
0032238783
-
2-isoprostanes in Alzheimer's disease: Evidence for enhanced lipid peroxidation in vivo
-
Pratico D, Lee VMY, Trojanowski JQ, Rokach J, Fitzgerald GA. Increased F-2-isoprostanes in Alzheimers disease: evidence for enhanced lipid peroxidation in vivo. FASEB J. 12(15), 1777-1783 (1998). (Pubitemid 28553673)
-
(1998)
FASEB Journal
, vol.12
, Issue.15
, pp. 1777-1783
-
-
Pratico, D.1
Lee, V.M.-Y.2
Trojanowski, J.Q.3
Rokach, J.4
Fitzgerald, G.A.5
-
49
-
-
0345305672
-
Neurosteroids: Cerebrospinal fluid levels for Alzheimer's disease and vascular dementia diagnostics
-
DOI 10.1210/jc.2003-030646
-
Kim SB, Hill M, Kwak YT, Hampl R, Jo DH, Morfin R. Neurosteroids: cerebrospinal fluid levels for Alzheimers disease and vascular dementia diagnostics. J. Clin. Endocr. Metab. 88(11), 5199-5206 (2003). (Pubitemid 37452716)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.11
, pp. 5199-5206
-
-
Kim, S.-B.1
Hill, M.2
Kwak, Y.-T.3
Hampl, R.4
Jo, D.-H.5
Morfin, R.6
-
50
-
-
33646103133
-
Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimers disease
-
Volkel W, Sicilia T, Pahler A, et al. Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimers disease. Neurochem. Int. 48(8), 679-686 (2006).
-
(2006)
Neurochem. Int.
, vol.48
, Issue.8
, pp. 679-686
-
-
Volkel, W.1
Sicilia, T.2
Pahler, A.3
-
51
-
-
1542713679
-
Determination of isoprostanes in urine samples from Alzheimer patients using porous graphitic carbon liquid chromatography-tandem mass spectrometry
-
DOI 10.1016/S1570-0232(03)00600-7, PII S1570023203006007
-
Bohnstedt KC, Karlberg B, Wahlund LO, Jonhagen ME, Basun H, Schmidt S. Determination of isoprostanes in urine samples from Alzheimer patients using porous graphitic carbon liquid chromatography- tandem mass spectrometry. J. Chromatogr. B 796(1), 11-19 (2003). (Pubitemid 38352705)
-
(2003)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.796
, Issue.1
, pp. 11-19
-
-
Bohnstedt, K.C.1
Karlberg, B.2
Wahlund, L.-O.3
Jonhagen, M.E.4
Basun, H.5
Schmidt, S.6
-
52
-
-
0035023152
-
Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: Molecular characterization using electrospray ionization mass spectrometry
-
DOI 10.1046/j.1471-4159.2001.00332.x
-
Han XL, Holtzman DM, McKeel DW. Plasmalogen deficiency in early Alzheimers disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry. J. Neurochem. 77(4), 1168-1180 (2001). (Pubitemid 32467071)
-
(2001)
Journal of Neurochemistry
, vol.77
, Issue.4
, pp. 1168-1180
-
-
Han, X.1
Holtzman, D.M.2
McKeel Jr., D.W.3
-
53
-
-
0015810617
-
Phospholipids and Acyl groups in subcellular-fractions from human cerebral-cortex
-
Sun GY. Phospholipids and Acyl groups in subcellular-fractions from human cerebral-cortex. J. Lipid Res. 14(6), 656-663 (1973).
-
(1973)
J. Lipid Res.
, vol.14
, Issue.6
, pp. 656-663
-
-
Sun, G.Y.1
-
55
-
-
0036677303
-
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimers disease: Potential role in disease pathogenesis
-
Han XL, Holtzman DM, McKeel DW, Kelley J, Morris JC. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimers disease: potential role in disease pathogenesis. J. Neurochem. 82(4), 809-818 (2002).
-
(2002)
J. Neurochem.
, vol.82
, Issue.4
, pp. 809-818
-
-
Han, X.L.1
Holtzman, D.M.2
McKeel, D.W.3
Kelley, J.4
Morris, J.C.5
-
56
-
-
26444507780
-
Improving LC-MS sensitivity through increases in chromatographic performance: Comparisons of UPLC-ES/MS/MS to HPLC-ES/MS/MS
-
DOI 10.1016/j.jchromb.2005.05.037, PII S1570023205004095, Improving Sensitivity in Liquid Chromatography-Mass Spectrometry
-
Churchwell MI, Twaddle NC, Meeker LR, Doerge DR. Improving LC-MS sensitivity through increases in chromatographic performance: comparisons of UPLC-ES- MS/MS to HPLC-ES-MS/MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 825(2), 134-143 (2005). (Pubitemid 41423596)
-
(2005)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.825
, Issue.2
, pp. 134-143
-
-
Churchwell, M.I.1
Twaddle, N.C.2
Meeker, L.R.3
Doerge, D.R.4
-
57
-
-
1842785179
-
Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
-
DOI 10.1016/j.ejphar.2004.02.049, PII S0014299904002067
-
Hoyer S. Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur. J. Pharmacol. 490(1-3), 115-125 (2004). (Pubitemid 38482165)
-
(2004)
European Journal of Pharmacology
, vol.490
, Issue.1-3
, pp. 115-125
-
-
Hoyer, S.1
-
58
-
-
0033653771
-
Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: An update
-
Hoyer S. Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update. Exp. Gerontol. 35(9-10), 1363-1372 (2000).
-
(2000)
Exp. Gerontol.
, vol.35
, Issue.9-10
, pp. 1363-1372
-
-
Hoyer, S.1
-
59
-
-
0028148336
-
Energy, oxidative damage, and Alzheimers-disease - Clues to the underlying puzzle
-
Beal MF. Energy, oxidative damage, and Alzheimers-disease - clues to the underlying puzzle. Neurobiol. Aging 15, S171-S174 (1994).
-
(1994)
Neurobiol. Aging
, vol.15
-
-
Beal, M.F.1
-
60
-
-
0031664279
-
Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients
-
Redjems-Bennani N, Jeandel C, Lefebvre E, Blain H, Vidailhet M, Gueant JL. Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients. Gerontology 44(5), 300-304 (1998). (Pubitemid 28403393)
-
(1998)
Gerontology
, vol.44
, Issue.5
, pp. 300-304
-
-
Redjems-Bennani, N.1
Jeandel, C.2
Lefebvre, E.3
Blain, H.4
Vidailhet, M.5
Gueant, J.-L.6
-
61
-
-
24644511602
-
Oxidative imbalance in Alzheimers disease
-
Zhu X, Lee HG, Casadesus G, et al. Oxidative imbalance in Alzheimers disease. Mol. Neurobiol. 31(1-3), 205-217 (2005).
-
(2005)
Mol. Neurobiol.
, vol.31
, Issue.1-3
, pp. 205-217
-
-
Zhu, X.1
Lee, H.G.2
Casadesus, G.3
-
63
-
-
0031594916
-
2-isoprostane levels are increased in Alzheimer's disease
-
DOI 10.1002/ana.410440322
-
Montine TJ, Markesbery WR, Morrow JD, Roberts LJ. Cerebrospinal fluid F-2- isoprostane levels are increased in Alzheimers disease. Ann. Neurol. 44(3), 410-413 (1998). (Pubitemid 28421451)
-
(1998)
Annals of Neurology
, vol.44
, Issue.3
, pp. 410-413
-
-
Montine, T.J.1
Markesbery, W.R.2
Morrow, J.D.3
Roberts II, L.J.4
-
64
-
-
0032588611
-
2-isoprostane concentration in probable AD
-
Montine TJ, Beal MF, Cudkowicz ME, et al. Increased CSF F-2-isoprostane concentration in probable AD. Neurology 52(3), 562-565 (1999). (Pubitemid 29075604)
-
(1999)
Neurology
, vol.52
, Issue.3
, pp. 562-565
-
-
Montine, T.J.1
Beal, M.F.2
Cudkowicz, M.E.3
O'Donnell, H.4
Margolin, R.A.5
McFarland, L.6
Bachrach, A.F.7
Zackert, W.E.8
Roberts, L.J.9
Morrow, J.D.10
-
65
-
-
0032740467
-
2 levels in patients with probable AD
-
Montine TJ, Sidell KR, Crews BC, et al. Elevated CSF prostaglandin E-2 levels in patients with probable AD. Neurology 53(7), 1495-1498 (1999). (Pubitemid 29491943)
-
(1999)
Neurology
, vol.53
, Issue.7
, pp. 1495-1498
-
-
Montine, T.J.1
Sidell, K.R.2
Crews, B.C.3
Markesbery, W.R.4
Marnett, L.J.5
Roberts II, L.J.6
Morrow, J.D.7
-
66
-
-
0034745018
-
2- isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls
-
Montine TJ, Kaye JA, Montine KS, McFarland L, Morrow JD, Quinn JF. Cerebrospinal fluid Ab(42), tau, and F-2-isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls. Arch. Pathol. Lab. Med. 125(4), 510-512 (2001). (Pubitemid 32291556)
-
(2001)
Archives of Pathology and Laboratory Medicine
, vol.125
, Issue.4
, pp. 510-512
-
-
Montine, T.J.1
Kaye, J.A.2
Montine, K.S.3
McFarland, L.4
Morrow, J.D.5
Quinn, J.F.6
-
67
-
-
1842584884
-
2-isoprostanes in Alzkeimer's disease
-
Quinn JF, Montine KS, Moore M, Morrow JD, Kaye JA, Montine TJ. Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimers disease. J. Alzheimers Dis. 6(1), 93-97 (2004). (Pubitemid 38418561)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.1
, pp. 93-97
-
-
Quinn, J.F.1
Montine, K.S.2
Moore, M.3
Morrow, J.D.4
Kaye, J.A.5
Montine, T.J.6
-
68
-
-
57749084707
-
Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimers disease patients and their potential as biomarkers
-
Yoshida Y, Yoshikawa A, Kinumi T, et al. Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimers disease patients and their potential as biomarkers. Neurobiol. Aging 30(2), 174-185 (2009).
-
(2009)
Neurobiol. Aging
, vol.30
, Issue.2
, pp. 174-185
-
-
Yoshida, Y.1
Yoshikawa, A.2
Kinumi, T.3
-
69
-
-
18844462415
-
Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease
-
DOI 10.1111/j.1471-4159.2005.03053.x
-
Wang J, Xiong S, Xie C, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimers disease. J. Neurochem. 93(4), 953-962 (2005). (Pubitemid 40695754)
-
(2005)
Journal of Neurochemistry
, vol.93
, Issue.4
, pp. 953-962
-
-
Wang, J.1
Xiong, S.2
Xie, C.3
Markesbery, W.R.4
Lovell, M.A.5
-
70
-
-
0037213976
-
Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology
-
DOI 10.1016/S0197-4580(02)00048-9, PII S0197458002000489
-
Brown RC, Han ZQ, Cascio C, Papadopoulos V. Oxidative stress-mediated DHEA formation in Alzheimers disease pathology. Neurobiol. Aging 24(1), 57-65 (2003). (Pubitemid 36001985)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.1
, pp. 57-65
-
-
Brown, R.C.1
Han, Z.2
Cascio, C.3
Papadopoulos, V.4
-
71
-
-
0031943120
-
Increased total 7α-hydroxy-dehydroepiandrosterone in serum of patients with Alzheimer's disease
-
Attal-Khemis S, Dalmeyda V, Michot JL, Roudier M, Morfin R. Increased total 7 a-hydroxy-dehydroepiandrosterone in serum of patients with Alzheimers disease. J. Gerontol. A Biol. Sci. Med. Sci. 53(2), B125-B132 (1998). (Pubitemid 28136140)
-
(1998)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.53
, Issue.2
-
-
Attal-Khemis, S.1
Dalmeyda, V.2
Michot, J.-L.3
Roudier, M.4
Morfin, R.5
-
72
-
-
69149109381
-
Greasing the wheels of Ab clearance in Alzheimers disease: The role of lipids and apolipoprotein e
-
Fan J, Donkin J, Wellington C. Greasing the wheels of Ab clearance in Alzheimers disease: the role of lipids and apolipoprotein E. BioFactors 35(3), 239-248 (2009).
-
(2009)
BioFactors
, vol.35
, Issue.3
, pp. 239-248
-
-
Fan, J.1
Donkin, J.2
Wellington, C.3
-
73
-
-
13244270042
-
Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment
-
DOI 10.1111/j.1471-4159.2004.02864.x
-
Ahmed N, Ahmed U, Thornalley PJ, Hager K, Fleischer G, Munch G. Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimers disease and link to cognitive impairment. J. Neurochem. 92(2), 255-263 (2005). (Pubitemid 40194017)
-
(2005)
Journal of Neurochemistry
, vol.92
, Issue.2
, pp. 255-263
-
-
Ahmed, N.1
Ahmed, U.2
Thornalley, P.J.3
Hager, K.4
Fleischer, G.5
Munch, G.6
-
74
-
-
38749084157
-
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
-
DOI 10.1016/j.jns.2007.08.041, PII S0022510X07006193
-
Gackowski D, Rozalski R, Siomek A, et al. Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/ vascular dementia. J. Neurol. Sci. 266(1-2), 57-62 (2008). (Pubitemid 351186523)
-
(2008)
Journal of the Neurological Sciences
, vol.266
, Issue.1-2
, pp. 57-62
-
-
Gackowski, D.1
Rozalski, R.2
Siomek, A.3
Dziaman, T.4
Nicpon, K.5
Klimarczyk, M.6
Araszkiewicz, A.7
Olinski, R.8
-
75
-
-
0042591280
-
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
-
DOI 10.1016/S0197-4580(03)00031-9
-
Rinaldi P, Polidori MC, Metastasio A, et al. Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimers disease. Neurobiol. Aging 24(7), 915-919 (2003). (Pubitemid 36962976)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.7
, pp. 915-919
-
-
Rinaldi, P.1
Polidori, M.C.2
Metastasio, A.3
Mariani, E.4
Mattioli, P.5
Cherubini, A.6
Catani, M.7
Cecchetti, R.8
Senin, U.9
Mecocci, P.10
-
76
-
-
40549113353
-
Nutritional biomarkers in Alzheimer's disease: The association between carotenoids, n-3 fatty acids, and dementia severity
-
Wang W, Shinto L, Connor WE, Quinn JF. Nutritional biomarkers in Alzheimers disease: the association between carotenoids, n-3 fatty acids, and dementia severity. J. Alzheimers Dis. 13(1), 31-38 (2008). (Pubitemid 351365625)
-
(2008)
Journal of Alzheimer's Disease
, vol.13
, Issue.1
, pp. 31-38
-
-
Wang, W.1
Shinto, L.2
Connor, W.E.3
Quinn, J.F.4
-
77
-
-
18544412891
-
Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease
-
DOI 10.1016/S0197-4580(98)00086-4, PII S0197458098000864
-
Sjögren M, Minthon L, Passant U, Blennow K, Wallin A. Decreased monoamine metabolites in frontotemporal dementia and Alzheimers disease. Neurobiol. Aging 19(5), 379-384 (1998). (Pubitemid 29065486)
-
(1998)
Neurobiology of Aging
, vol.19
, Issue.5
, pp. 379-384
-
-
Sjogren, M.1
Minthon, L.2
Passant, U.3
Blennow, K.4
Wallin, A.5
-
78
-
-
33747400567
-
Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia
-
DOI 10.1016/j.schres.2006.05.001, PII S0920996406002258
-
Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J. Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. Schizophr. Res. 86(1-3), 45-53 (2006). (Pubitemid 44251276)
-
(2006)
Schizophrenia Research
, vol.86
, Issue.1-3
, pp. 45-53
-
-
Marcelis, M.1
Suckling, J.2
Hofman, P.3
Woodruff, P.4
Bullmore, E.5
Van Os, J.6
-
79
-
-
4644304936
-
Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients
-
DOI 10.1016/j.neurobiolaging.2004.02.016, PII S0197458004001186
-
Walter A, Korth U, Hilgert M, et al. Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients. Neurobiol. Aging 25(10), 1299-1303 (2004). (Pubitemid 39299166)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.10
, pp. 1299-1303
-
-
Walter, A.1
Korth, U.2
Hilgert, M.3
Hartmann, J.4
Weichel, O.5
Hilgert, M.6
Fassbender, K.7
Schmitt, A.8
Klein, J.9
-
80
-
-
18444387712
-
Discovery of biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis coupled to mass spectrometry: Towards new diagnostic and therapeutic approaches
-
DOI 10.1002/elps.200410140
-
Wittke S, Mischak H, Walden M, Kolch W, Radler T, Wiedemann K. Discovery of biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis coupled to mass spectrometry: towards new diagnostic and therapeutic approaches. Electrophoresis 26(7-8), 1476-1487 (2005). (Pubitemid 40645466)
-
(2005)
Electrophoresis
, vol.26
, Issue.7-8
, pp. 1476-1487
-
-
Wittke, S.1
Mischak, H.2
Walden, M.3
Kolch, W.4
Radler, T.5
Wiedemann, K.6
-
81
-
-
56749185549
-
Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimers disease
-
Verpillot R, Otto M, Klafki H, Taverna M. Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimers disease. J. Chromatogr. A 1214(1-2), 157-164 (2008).
-
(2008)
J. Chromatogr. A
, vol.1214
, Issue.1-2
, pp. 157-164
-
-
Verpillot, R.1
Otto, M.2
Klafki, H.3
Taverna, M.4
-
82
-
-
65949093940
-
CE can identify small molecules that selectively target soluble oligomers of amyloid b protein and display antifibrillogenic activity
-
Colombo R, Carotti A, Catto M, et al. CE can identify small molecules that selectively target soluble oligomers of amyloid b protein and display antifibrillogenic activity. Electrophoresis 30(8), 1418-1429 (2009).
-
(2009)
Electrophoresis
, vol.30
, Issue.8
, pp. 1418-1429
-
-
Colombo, R.1
Carotti, A.2
Catto, M.3
-
83
-
-
0034683070
-
Chiral separation of amino acids in biological fluids by micellar electrokinetic chromatography with laser-induced fluorescence detection
-
DOI 10.1016/S0378-4347(00)00310-8, PII S0378434700003108
-
Thorsen G, Bergquist J. Chiral separation of amino acids in biological fluids by micellar electrokinetic chromatography with laser-induced fluorescence detection. J. Chromatogr. B 745(2), 389-397 (2000). (Pubitemid 30665563)
-
(2000)
Journal of Chromatography B: Biomedical Sciences and Applications
, vol.745
, Issue.2
, pp. 389-397
-
-
Thorsen, G.1
Bergquist, J.2
-
84
-
-
0025784371
-
Free d-aspartate and d-alanine in normal and Alzheimer brain
-
Fisher GH, Daniello A, Vetere A, Padula L, Cusano GP, Man EH. Free d-aspartate and d-alanine in normal and Alzheimer brain. Brain Res. Bull. 26(6), 983-985 (1991).
-
(1991)
Brain Res. Bull.
, vol.26
, Issue.6
, pp. 983-985
-
-
Fisher, G.H.1
Daniello, A.2
Vetere, A.3
Padula, L.4
Cusano, G.P.5
Man, E.H.6
-
85
-
-
33847524027
-
Capillary zone electrophoretic determination of 5-hydroxy-indoleacetic acid and homovanillic acid in cerebrospinal fluid from patients with neuropsychiatric disorders
-
Hiraoka A, Arato T, Tominaga I. Capillary zone electrophoretic determination of 5-hydroxy-indoleacetic acid and homovanillic acid in cerebrospinal fluid from patients with neuropsychiatric disorders. Jpn. J. Electrophor. 40(4), 193-197 (1996).
-
(1996)
Jpn. J. Electrophor.
, vol.40
, Issue.4
, pp. 193-197
-
-
Hiraoka, A.1
Arato, T.2
Tominaga, I.3
-
86
-
-
34250014357
-
CZE determination of quinolinic acid in rat brain tissue and plasma
-
DOI 10.1365/s10337-007-0241-7
-
Tenorio-Lopez FA, del Valle-Mondragon L, Martinez-Lazcano JC, et al. CZE determination of quinolinic acid in rat brain tissue and plasma. Chromatographia 65(11-12), 725-731 (2007). (Pubitemid 46883634)
-
(2007)
Chromatographia
, vol.65
, Issue.11-12
, pp. 725-731
-
-
Tenorio-Lopez, F.A.1
Del Valle-Mondragon, L.2
Martinez-Lazcano, J.C.3
Sanchez-Mendoza, A.4
Rios, C.5
Pastelin-Hernandez, G.6
Perez-Severiano, F.7
-
87
-
-
0027180115
-
MK-801, an N-methyl-D-aspartate receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum
-
Santamaria A, Rios C. Mk-801, an N-methyl-d-aspartate receptor antagonist, blocks quinolinic acid-induced lipid-peroxidation in rat corpus striatum. Neurosci. Lett. 159(1-2), 51-54 (1993). (Pubitemid 23283236)
-
(1993)
Neuroscience Letters
, vol.159
, Issue.1-2
, pp. 51-54
-
-
Santamaria, A.1
Rios, C.2
-
88
-
-
27944460979
-
Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats
-
DOI 10.1016/j.ijdevneu.2005.08.004, PII S0736574805001115
-
Leipnitz G, Schumacher C, Scussiato K, et al. Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats. Int. J. Dev. Neurosci. 23(8), 695-701 (2005). (Pubitemid 41674508)
-
(2005)
International Journal of Developmental Neuroscience
, vol.23
, Issue.8
, pp. 695-701
-
-
Leipnitz, G.1
Schumacher, C.2
Scussiato, K.3
Dalcin, K.B.4
Wannmacher, C.M.D.5
Wyse, A.T.D.6
Dutra-Filho, C.S.7
Wajner, M.8
Latini, A.9
-
89
-
-
67650178847
-
The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection
-
Vamos E, Pardutz A, Klivenyi P, Toldi J, Vecsei L. The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection. J. Neurol. Sci. 283(1-2), 21-27 (2009).
-
(2009)
J. Neurol. Sci.
, vol.283
, Issue.1-2
, pp. 21-27
-
-
Vamos, E.1
Pardutz, A.2
Klivenyi, P.3
Toldi, J.4
Vecsei, L.5
-
90
-
-
0036378826
-
Implications of the kynurenine pathway and quinolinic acid in Alzheimers disease
-
Guillemin GJ, Brew BJ. Implications of the kynurenine pathway and quinolinic acid in Alzheimers disease. Redox Rep. 7(4), 199-206 (2002).
-
(2002)
Redox Rep.
, vol.7
, Issue.4
, pp. 199-206
-
-
Guillemin, G.J.1
Brew, B.J.2
-
91
-
-
0032866415
-
Plasma levels of 8-epiPGF2α, an in vivo marker of oxidative stress, are not affected by aging or Alzheimer's disease
-
DOI 10.1016/S0891-5849(99)00096-9, PII S0891584999000969
-
Feillet-Coudray C, Tourtauchaux R, Niculescu M, et al. Plasma levels of 8-epiPGF2 [a], an in vivo marker of oxidative stress, are not affected by aging or Alzheimers disease. Free Radical Bio. Med. 27(3-4), 463-469 (1999). (Pubitemid 29395442)
-
(1999)
Free Radical Biology and Medicine
, vol.27
, Issue.3-4
, pp. 463-469
-
-
Feillet-Coudray, C.1
Tourtauchaux, R.2
Niculescu, M.3
Rock, E.4
Tauveron, I.5
Alexandre-Gouabau, M.-C.6
Rayssiguier, Y.7
Jalenques, I.8
Mazur, A.9
-
92
-
-
0347995011
-
Alzheimers disease
-
Armanini D, Vecchio F, Basso A, et al. Alzheimers disease. Endocrine 22(2), 113-118 (2003).
-
(2003)
Endocrine
, vol.22
, Issue.2
, pp. 113-118
-
-
Armanini, D.1
Vecchio, F.2
Basso, A.3
-
93
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimers disease. J. Neurosci. 17(8), 2653-2657 (1997). (Pubitemid 27154998)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.8
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
94
-
-
54549091125
-
Systems biology - Metabonomics
-
Nicholson JK, Lindon JC. Systems biology - metabonomics. Nature 455(7216), 1054-1056 (2008).
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1054-1056
-
-
Nicholson, J.K.1
Lindon, J.C.2
-
95
-
-
65949120933
-
A proposed metabolic strategy for monitoring disease progression in Alzheimers disease
-
Greenberg N, Grassano A, Thambisetty M, Lovestone S, Legido-Quigley C. A proposed metabolic strategy for monitoring disease progression in Alzheimers disease. Electrophoresis 30(7), 1235-1239 (2009).
-
(2009)
Electrophoresis
, vol.30
, Issue.7
, pp. 1235-1239
-
-
Greenberg, N.1
Grassano, A.2
Thambisetty, M.3
Lovestone, S.4
Legido-Quigley, C.5
-
96
-
-
72549095180
-
Chemometrics in metabolomics - A review in human disease diagnosis
-
Madsen R, Lundstedt T, Trygg J. Chemometrics in metabolomics - a review in human disease diagnosis. Anal. Chim. Acta 659(1-2), 23-33 (2010).
-
(2010)
Anal. Chim. Acta 659
, vol.1
, Issue.2
, pp. 23-33
-
-
Madsen, R.1
Lundstedt, T.2
Trygg, J.3
-
97
-
-
0036913503
-
1H-NMR-based metabonomics
-
DOI 10.1038/nm802
-
Brindle JT, Antti H, Holmes E, et al. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nat. Med. 8(12), 1439-1444 (2002). (Pubitemid 36019430)
-
(2002)
Nature Medicine
, vol.8
, Issue.12
, pp. 1439-1444
-
-
Brindle, J.T.1
Antti, H.2
Holmes, E.3
Tranter, G.4
Nicholson, J.K.5
Bethell, H.W.L.6
Clarke, S.7
Schofield, P.M.8
McKilligin, E.9
Mosedale, D.E.10
Grainger, D.J.11
-
98
-
-
33846977711
-
Metabonomics in pharmaceutical R&D
-
Lindon JC, Holmes E, Nicholson JK. Metabonomics in pharmaceutical R&D. FEBS J. 274(5), 1140-1151 (2007).
-
(2007)
FEBS J.
, vol.274
, Issue.5
, pp. 1140-1151
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
99
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
DOI 10.1038/nature06882, PII NATURE06882
-
Holmes E, Loo RL, Stamler J, et al. Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 453(7193), 396-400 (2008). (Pubitemid 351693125)
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
Bictash, M.4
Yap, I.K.S.5
Chan, Q.6
Ebbels, T.7
De Iorio, M.8
Brown, I.J.9
Veselkov, K.A.10
Daviglus, M.L.11
Kesteloot, H.12
Ueshima, H.13
Zhao, L.14
Nicholson, J.K.15
Elliott, P.16
-
100
-
-
33645781275
-
Metabolic profiling of plasma from discordant schizophrenia twins: Correlation between lipid signals and global functioning in female schizophrenia patients
-
Tsang TM, Huang JTJ, Holmes E, Bahn S. Metabolic profiling of plasma from discordant schizophrenia twins: correlation between lipid signals and global functioning in female schizophrenia patients. J. Proteome Res. 5(4), 756-760 (2006).
-
(2006)
J. Proteome Res.
, vol.5
, Issue.4
, pp. 756-760
-
-
Tsang, T.M.1
Jtj, H.2
Holmes, E.3
Bahn, S.4
-
101
-
-
33748354488
-
Metabolic profiling of CSF: Evidence that early intervention may impact on disease progression and outcome in schizophrenia
-
Holmes E, Tsang TM, Huang JTJ, et al. Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. PLoS Med. 3(8), e327 (2006).
-
(2006)
PLoS Med.
, vol.3
, Issue.8
-
-
Holmes, E.1
Tsang, T.M.2
Jtj, H.3
-
102
-
-
60549109881
-
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder
-
Lan MJ, McLoughlin GA, Griffin JL, et al. Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder. Mol. Psychiatry 14, 269-279 (2008).
-
(2008)
Mol. Psychiatry
, vol.14
, pp. 269-279
-
-
Lan, M.J.1
McLoughlin, G.A.2
Griffin, J.L.3
-
103
-
-
0027564324
-
NMR-spectroscopy of human postmortem cerebrospinal-fluid - Distinction of Alzheimers-disease from control using pattern-recognition and statistics
-
Ghauri FYK, Nicholson JK, Sweatman BC, et al. NMR-spectroscopy of human postmortem cerebrospinal-fluid - distinction of Alzheimers-disease from control using pattern-recognition and statistics. NMR Biomed. 6(2), 163-167 (1993).
-
(1993)
NMR Biomed.
, vol.6
, Issue.2
, pp. 163-167
-
-
Fyk, G.1
Nicholson, J.K.2
Sweatman, B.C.3
-
104
-
-
50849141305
-
A multimetabolite analysis of serum by H-1 NMR spectroscopy: Early systemic signs of Alzheimers disease
-
Tukiainen T, Tynkkynen T, Makinen VP, et al. A multimetabolite analysis of serum by H-1 NMR spectroscopy: early systemic signs of Alzheimers disease. Biochem. Bioph. Res. Co. 375(3), 356-361 (2008).
-
(2008)
Biochem. Bioph. Res. Co.
, vol.375
, Issue.3
, pp. 356-361
-
-
Tukiainen, T.1
Tynkkynen, T.2
Makinen, V.P.3
-
105
-
-
16844365618
-
Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy
-
DOI 10.1176/appi.ajp.162.4.667
-
Modrego PJ, Fayed N, Pina MA. Conversion from mild cognitive impairment to probable Alzheimers disease predicted by brain magnetic resonance spectroscopy. Am. J. Psychiatry, 162(4), 667-675 (2005). (Pubitemid 40489127)
-
(2005)
American Journal of Psychiatry
, vol.162
, Issue.4
, pp. 667-675
-
-
Modrego, P.J.1
Fayed, N.2
Pina, M.A.3
-
106
-
-
77953124257
-
A metabolomic study of the CRND8 transgenic mouse model of Alzheimers disease
-
Salek RM, Xia J, Innes A, et al. A metabolomic study of the CRND8 transgenic mouse model of Alzheimers disease. Neurochem. Int. 56(8), 937-947 (2010).
-
(2010)
Neurochem. Int.
, vol.56
, Issue.8
, pp. 937-947
-
-
Salek, R.M.1
Xia, J.2
Innes, A.3
-
107
-
-
84859498953
-
Serum fatty acid profiles using GC-MS and multivariate statistical analysis: Potential biomarkers of Alzheimers disease
-
DOI: 10.1016/j.neurobiolaging.2010. 09.013 Epub ahead of print
-
Wang D-C, Sun C-H, Liu L-Y, et al. Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimers disease. Neurobiol. Aging DOI: 10.1016/j.neurobiolaging.2010. 09.013 (2010) (Epub ahead of print).
-
(2010)
Neurobiol. Aging
-
-
Wang, D.-C.1
Sun, C.-H.2
Liu, L.-Y.3
-
108
-
-
77954510398
-
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease
-
Thambisetty M, Simmons A, Velayudhan L, et al. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch. Gen. Psychiatry 67(7), 739-748 (2010).
-
(2010)
Arch. Gen. Psychiatry
, vol.67
, Issue.7
, pp. 739-748
-
-
Thambisetty, M.1
Simmons, A.2
Velayudhan, L.3
-
109
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimers disease
-
Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimers disease. Nat. Genet. 41(10), 1088-1093 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.10
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
-
110
-
-
71549148689
-
The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF)
-
Rosenling T, Slim CL, Christin C, et al. The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF). J. Proteome Res. 8(12), 5511-5522 (2009).
-
(2009)
J. Proteome Res.
, vol.8
, Issue.12
, pp. 5511-5522
-
-
Rosenling, T.1
Slim, C.L.2
Christin, C.3
-
111
-
-
79956197867
-
-
What is Alzheimers Disease? Alzheimers Society
-
What is Alzheimers Disease? Alzheimers Society (2008). http://alzheimers.org.uk/site/scripts/ documents-info.php?documentID=100
-
(2008)
-
-
|