RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 10, 2011, Pages 1322-1335

  Ma, Bing ^a   Dela Cruz, Charles S ^a   Hartl, Dominik ^a,b   Kang, Min Jong ^a   Takyar, Shervin ^a   Homer, Robert J ^a   Lee, Chun Geun ^a   Elias, Jack A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Chronic obstructive pulmonary disease; Influenza virus; Mitochondrial antiviral signaling molecule; RIG like helicase

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOCAL ADHESION KINASE; HELICASE; INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE 3; MUCIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE B; RETINOIC ACID INDUCIBLE GENE LIKE HELICASE; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; HELPER CELL; INFLUENZA VIRUS; INNATE IMMUNITY; LUNG BLOOD VESSEL; LUNG EDEMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFLAMMATION; TRANSGENE; VIRUS IMMUNITY;

ANIMALS; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; EDEMA; FOCAL ADHESION PROTEIN-TYROSINE KINASES; IMMUNITY, INNATE; INFLAMMATION; INTERFERON TYPE I; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHATIDYLINOSITOL 3-KINASE; POLY I-C; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TOLL-LIKE RECEPTOR 3; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79956196180     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201008-1276OC     Document Type: Article

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