Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

American Journal of Respiratory Cell and Molecular Biology

Volumn 39, Issue 6, 2008, Pages 739-746

  Chun, Geun Lee ^a   Hartl, Dominik ^a   Matsuura, Hiroshi ^a   Dunlop, Felicity M ^b   Scotney, Pierre D ^b   Fabri, Louis J ^b   Nash, Andrew D ^b   Chen, Ning Yuan ^a   Tang, Chu Yan ^a   Chen, Qingsheng ^a   Homer, Robert J ^a   Baca, Manuel ^b   Elias, Jack A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CSL LIMITED   (Australia)

Author keywords

Airway inflammation; IL 11; IL 13; Mucus; Mutein

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 11; INTERLEUKIN 11 RECEPTOR ALPHA; INTERLEUKIN 13; MUTEIN; OVALBUMIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

AEROSOL; AIRWAY MUCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; INTERVENTION STUDY; LUNG; LUNG LAVAGE; MOUSE; MUCUS; MUCUS SECRETION; MUTANT; MUTATION; NONHUMAN; PNEUMONIA; REGULATORY MECHANISM; SENSITIZATION; TRANSGENIC MOUSE; WILD TYPE;

ALLERGENS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; GENE EXPRESSION REGULATION; IMMUNIZATION; INFLAMMATION; INTERLEUKIN-11; INTERLEUKIN-13; MICE; MICE, INBRED C57BL; MUCIN 5AC; MUCUS; OVALBUMIN; PHENOTYPE; RECEPTORS, INTERLEUKIN-11; SIGNAL TRANSDUCTION; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; MUS; MUS MUSCULUS;

EID: 57349151546     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0053OC     Document Type: Article

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