메뉴 건너뛰기




Volumn 48, Issue 1, 1999, Pages 158-169

Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 0032939904     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.1.158     Document Type: Article
Times cited : (91)

References (62)
  • 1
    • 0026021161 scopus 로고
    • Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194, 1991
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 2
    • 0022250141 scopus 로고
    • Cellular mechanisms in selected states of insulin resistance: Human obesity, glucocorticoid excess, and chronic renal failure
    • Amatruda JM, Livingston JN, Lockwood DH. Cellular mechanisms in selected states of insulin resistance: human obesity, glucocorticoid excess, and chronic renal failure. Diabetes Metab Rev 1:293-317, 1985
    • (1985) Diabetes Metab Rev , vol.1 , pp. 293-317
    • Amatruda, J.M.1    Livingston, J.N.2    Lockwood, D.H.3
  • 3
    • 0019473012 scopus 로고
    • Effects of prednisolone and dexamethasone in vivo and in vitro: Studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes
    • De Pirro R, Green A, Kao MY, Olefsky JM: Effects of prednisolone and dexamethasone in vivo and in vitro: studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes. Diabetologia 21:149-153, 1981
    • (1981) Diabetologia , vol.21 , pp. 149-153
    • De Pirro, R.1    Green, A.2    Kao, M.Y.3    Olefsky, J.M.4
  • 4
    • 0016708685 scopus 로고
    • Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes
    • Olefsky JM: Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest 56:1499-1508, 1975
    • (1975) J Clin Invest , vol.56 , pp. 1499-1508
    • Olefsky, J.M.1
  • 5
    • 0020050650 scopus 로고
    • Glucocorticoid-induced insulin resistance: The importance of postbinding events in the regulation of insulin binding, action, and degradation in freshly isolated and primary cultures of rat hepatocytes
    • Caro JF, Amatruda JM: Glucocorticoid-induced insulin resistance: the importance of postbinding events in the regulation of insulin binding, action, and degradation in freshly isolated and primary cultures of rat hepatocytes. J Clin Invest 69:866-875, 1982
    • (1982) J Clin Invest , vol.69 , pp. 866-875
    • Caro, J.F.1    Amatruda, J.M.2
  • 6
    • 0021879053 scopus 로고
    • Glucose tolerance and physical activity in a health survey of middle-aged subjects
    • Cederholm J, Wibell L: Glucose tolerance and physical activity in a health survey of middle-aged subjects. Acta Med Scand 217:373-378, 1985
    • (1985) Acta Med Scand , vol.217 , pp. 373-378
    • Cederholm, J.1    Wibell, L.2
  • 7
    • 0023026240 scopus 로고
    • Lower prevalence of diabetes in female former college athletes compared with nonathletes
    • Frisch RE, Wyshak G, Albright TE, Albright NL, Schiff I: Lower prevalence of diabetes in female former college athletes compared with nonathletes. Diabetes 35:1101-1105, 1986
    • (1986) Diabetes , vol.35 , pp. 1101-1105
    • Frisch, R.E.1    Wyshak, G.2    Albright, T.E.3    Albright, N.L.4    Schiff, I.5
  • 9
    • 0020033858 scopus 로고
    • Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet
    • Grundleger ML, Thenen SW: Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet. Diabetes 31:232-237, 1982
    • (1982) Diabetes , vol.31 , pp. 232-237
    • Grundleger, M.L.1    Thenen, S.W.2
  • 10
    • 0018097666 scopus 로고
    • In-vitro and in-vivo responsiveness of muscle and adipose tissue to insulin in rats rendered obese by a high-fat diet
    • Susini C, Lavau M: In-vitro and in-vivo responsiveness of muscle and adipose tissue to insulin in rats rendered obese by a high-fat diet Diabetes 27:114-120, 1978
    • (1978) Diabetes , vol.27 , pp. 114-120
    • Susini, C.1    Lavau, M.2
  • 11
    • 0022977709 scopus 로고
    • Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats
    • Storlien LH, James DE, Burleigh KM, Chisholm DJ, Kraegen EW: Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. Am J Physiol 251:E576-E583, 1986
    • (1986) Am J Physiol , vol.251
    • Storlien, L.H.1    James, D.E.2    Burleigh, K.M.3    Chisholm, D.J.4    Kraegen, E.W.5
  • 13
    • 0025054595 scopus 로고
    • A prospective population-based study of alcohol use and non-insulin-dependent diabetes mellitus
    • Holbrook TL, Barrett-Connor E, Wingard DL: A prospective population-based study of alcohol use and non-insulin-dependent diabetes mellitus. Am J Epidemiol 132:902-909, 1990
    • (1990) Am J Epidemiol , vol.132 , pp. 902-909
    • Holbrook, T.L.1    Barrett-Connor, E.2    Wingard, D.L.3
  • 14
    • 0024370286 scopus 로고
    • Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats
    • Thorburn AW, Storlien LH, Jenkins AB, Khouri S, Kraegen EW: Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am J Clin Nutr 49:1155-1163, 1989
    • (1989) Am J Clin Nutr , vol.49 , pp. 1155-1163
    • Thorburn, A.W.1    Storlien, L.H.2    Jenkins, A.B.3    Khouri, S.4    Kraegen, E.W.5
  • 15
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 s6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR: Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 17
    • 0028124189 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes: Studies with a selective inhibitor wortmannin
    • Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M: Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes: studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573, 1994
    • (1994) J Biol Chem , vol.269 , pp. 3568-3573
    • Okada, T.1    Kawano, Y.2    Sakakibara, T.3    Hazeki, O.4    Ui, M.5
  • 18
  • 19
    • 0029160069 scopus 로고
    • Protein kinase b (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602, 1995
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 21
    • 0028797745 scopus 로고
    • Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: Evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase
    • Shepherd PR, Nave BT, Siddle K: Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase. Biochem J 305:25-28, 1995
    • (1995) Biochem J , vol.305 , pp. 25-28
    • Shepherd, P.R.1    Nave, B.T.2    Siddle, K.3
  • 22
    • 0028982829 scopus 로고
    • Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression
    • Sutherland C, O'Brien RM, Granner DK: Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression. J Biol Chem 270:15501-15506, 1995
    • (1995) J Biol Chem , vol.270 , pp. 15501-15506
    • Sutherland, C.1    O'Brien, R.M.2    Granner, D.K.3
  • 23
    • 0030050975 scopus 로고    scopus 로고
    • Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway
    • Gabbay RA, Sutherland C, Gnudi L, Kahn BB, O'Brien RM, Granner DK, Flier JS: Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway. J Biol Chem 271:1890-1897, 1996
    • (1996) J Biol Chem , vol.271 , pp. 1890-1897
    • Gabbay, R.A.1    Sutherland, C.2    Gnudi, L.3    Kahn, B.B.4    O'Brien, R.M.5    Granner, D.K.6    Flier, J.S.7
  • 24
    • 0027484001 scopus 로고
    • Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus
    • Folli F, Saad MJ, Backer JM, Kahn CR: Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J Clin Invest 92:1787-1794, 1993
    • (1993) J Clin Invest , vol.92 , pp. 1787-1794
    • Folli, F.1    Saad, M.J.2    Backer, J.M.3    Kahn, C.R.4
  • 25
    • 0028964599 scopus 로고
    • Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells
    • Saad MJ, Folli F, Kahn CR: Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells. Endocrinology 136:1579-1588, 1995
    • (1995) Endocrinology , vol.136 , pp. 1579-1588
    • Saad, M.J.1    Folli, F.2    Kahn, C.R.3
  • 26
    • 0027489828 scopus 로고
    • Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
    • Saad MJ, Folli F, Kahn JA, Kahn CR: Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92:2065-2072, 1993
    • (1993) J Clin Invest , vol.92 , pp. 2065-2072
    • Saad, M.J.1    Folli, F.2    Kahn, J.A.3    Kahn, C.R.4
  • 27
    • 0030066985 scopus 로고    scopus 로고
    • Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats
    • Carvalho CR, Brenelli SL, Silva AC, Nunes AL, Velloso LA, Saad MJ: Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats. Endocrinology 137:151-159, 1996
    • (1996) Endocrinology , vol.137 , pp. 151-159
    • Carvalho, C.R.1    Brenelli, S.L.2    Silva, A.C.3    Nunes, A.L.4    Velloso, L.A.5    Saad, M.J.6
  • 29
    • 0028903232 scopus 로고
    • Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
    • Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL: Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest 95:2195-2204, 1995
    • (1995) J Clin Invest , vol.95 , pp. 2195-2204
    • Goodyear, L.J.1    Giorgino, F.2    Sherman, L.A.3    Carey, J.4    Smith, R.J.5    Dohm, G.L.6
  • 30
    • 0022973181 scopus 로고
    • In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin
    • James DE, Burleigh KM, Kraegen EW: In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin. J Biol Chem 261:6366-6374, 1986
    • (1986) J Biol Chem , vol.261 , pp. 6366-6374
    • James, D.E.1    Burleigh, K.M.2    Kraegen, E.W.3
  • 34
    • 0024936235 scopus 로고
    • Cellular alterations in liver, skeletal muscle, and adipose tissue responsible for insulin resistance in obesity and type II diabetes
    • Caro JF, Dohm LG, Portes WJ, Sinha MK: Cellular alterations in liver, skeletal muscle, and adipose tissue responsible for insulin resistance in obesity and type II diabetes. Diabetes Metab Rev 5:665-689, 1989
    • (1989) Diabetes Metab Rev , vol.5 , pp. 665-689
    • Caro, J.F.1    Dohm, L.G.2    Portes, W.J.3    Sinha, M.K.4
  • 35
    • 0028085078 scopus 로고
    • The insulin signaling system
    • White MF, Kahn CR: The insulin signaling system. J Biol Chem 269:1-4, 1994
    • (1994) J Biol Chem , vol.269 , pp. 1-4
    • White, M.F.1    Kahn, C.R.2
  • 36
    • 0027424828 scopus 로고
    • Molecular determinants of insulin action
    • Kahn CR, Folli F: Molecular determinants of insulin action. Horm Res 39 (Suppl. 3):93-101, 1993
    • (1993) Horm Res , vol.39 , Issue.3 SUPPL. , pp. 93-101
    • Kahn, C.R.1    Folli, F.2
  • 37
    • 0028260280 scopus 로고
    • Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
    • Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD: Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J 300:631-635, 1994
    • (1994) Biochem J , vol.300 , pp. 631-635
    • Clarke, J.F.1    Young, P.W.2    Yonezawa, K.3    Kasuga, M.4    Holman, G.D.5
  • 40
    • 0022628695 scopus 로고
    • In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: Assessment by euglycaemic clamp plus deoxyglucose administration
    • Kraegen EW, James DE, Storlien LH, Burleigh KM, Chisholm DJ: In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration. Diabetologia 29:192-198, 1986
    • (1986) Diabetologia , vol.29 , pp. 192-198
    • Kraegen, E.W.1    James, D.E.2    Storlien, L.H.3    Burleigh, K.M.4    Chisholm, D.J.5
  • 41
    • 0022996786 scopus 로고
    • Effect of diet change on insulin action: Difference between muscles and adipocytes
    • Maegawa H, Kobayashi M, Ishibashi O, Takata Y, Shigeta Y: Effect of diet change on insulin action: difference between muscles and adipocytes. Am J Physiol 251:E616-E623, 1986
    • (1986) Am J Physiol , vol.251
    • Maegawa, H.1    Kobayashi, M.2    Ishibashi, O.3    Takata, Y.4    Shigeta, Y.5
  • 42
    • 0026666965 scopus 로고
    • A high-fat diet worsens metabolic control in streptozotocin-treated rats by increasing hepatic glucose production
    • Traianedes K, Proietto J, O'Dea K: A high-fat diet worsens metabolic control in streptozotocin-treated rats by increasing hepatic glucose production. Metabolism 41:846-850, 1992
    • (1992) Metabolism , vol.41 , pp. 846-850
    • Traianedes, K.1    Proietto, J.2    O'Dea, K.3
  • 44
    • 0030987889 scopus 로고    scopus 로고
    • High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect
    • Zierath JR, Houseknecht KL, Gnudi L, Kahn BB: High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes 46:215-223, 1997
    • (1997) Diabetes , vol.46 , pp. 215-223
    • Zierath, J.R.1    Houseknecht, K.L.2    Gnudi, L.3    Kahn, B.B.4
  • 45
    • 0030798932 scopus 로고    scopus 로고
    • Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes
    • Ozanne SE, Nave BT, Wang CL, Shepherd FR, Prins J, Smith GD: Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes. Am J Physiol 273:E46-E51, 1997
    • (1997) Am J Physiol , vol.273
    • Ozanne, S.E.1    Nave, B.T.2    Wang, C.L.3    Shepherd, F.R.4    Prins, J.5    Smith, G.D.6
  • 49
    • 0027212268 scopus 로고
    • The new elements of insulin signaling: Insulin receptor substrate-1 and proteins with SH2 domains
    • Myers MG Jr, White MF: The new elements of insulin signaling: insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650, 1993
    • (1993) Diabetes , vol.42 , pp. 643-650
    • Myers M.G., Jr.1    White, M.F.2
  • 52
    • 0031015407 scopus 로고
    • Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone
    • Antonucci T, Whitcomb R, McLain R, Lockwood D: Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone. Diabetes Care 20:188-193, 1907
    • (1907) Diabetes Care , vol.20 , pp. 188-193
    • Antonucci, T.1    Whitcomb, R.2    McLain, R.3    Lockwood, D.4
  • 54
    • 0029782274 scopus 로고    scopus 로고
    • Erratum published
    • Kumar S, Boulton AJ, Beck-Nielsen H, Berthezene F, Muggeo M, Persson B, Spinas GA, Donoghue S, Lettis S, Stewart-Long P: Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients: Troglitazone Study Group. Diabetologia 39:701-709, 1996 (Erratum published in Diabetologia 39:1245, 1996)
    • (1996) Diabetologia , vol.39 , pp. 1245
  • 57
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-artivated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-artivated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 58
    • 0028032417 scopus 로고
    • Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and l6 myotubes
    • Zhang B, Szalkowski D, Diaz E, Hayes N, Smith R, Berger J: Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes. J Biol Chem 269:25735-25741, 1994
    • (1994) J Biol Chem , vol.269 , pp. 25735-25741
    • Zhang, B.1    Szalkowski, D.2    Diaz, E.3    Hayes, N.4    Smith, R.5    Berger, J.6
  • 59
    • 0026766036 scopus 로고
    • Pioglitazone increases insulin sensitivity by activating insulin receptor kinase
    • Kobayashi M, Iwanishi M, Egawa K, Shigeta Y: Pioglitazone increases insulin sensitivity by activating insulin receptor kinase. Diabetes 41:476-483, 1992
    • (1992) Diabetes , vol.41 , pp. 476-483
    • Kobayashi, M.1    Iwanishi, M.2    Egawa, K.3    Shigeta, Y.4
  • 60
    • 0028884048 scopus 로고
    • Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes: Association with increased insulin binding and cell-surface glut4 as measured by photoaffinity labeling
    • Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, Kirkham DM, Lister CA, Smith SA: Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes: association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling. Diabetes 44:1087-1092, 1995
    • (1995) Diabetes , vol.44 , pp. 1087-1092
    • Young, P.W.1    Cawthorne, Ma.2    Coyle, P.J.3    Holder, J.C.4    Holman, G.D.5    Kozka, I.J.6    Kirkham, D.M.7    Lister, C.A.8    Smith, S.A.9
  • 62
    • 0028305633 scopus 로고
    • Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism
    • Sizer KM, Smith CL, Jacob CS, Swanson ML, Bleasdale JE: Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism. Mol Cell Endocrinol 103:1-12, 1994
    • (1994) Mol Cell Endocrinol , vol.103 , pp. 1-12
    • Sizer, K.M.1    Smith, C.L.2    Jacob, C.S.3    Swanson, M.L.4    Bleasdale, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.