-
1
-
-
0026021161
-
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194, 1991
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
2
-
-
0022250141
-
Cellular mechanisms in selected states of insulin resistance: Human obesity, glucocorticoid excess, and chronic renal failure
-
Amatruda JM, Livingston JN, Lockwood DH. Cellular mechanisms in selected states of insulin resistance: human obesity, glucocorticoid excess, and chronic renal failure. Diabetes Metab Rev 1:293-317, 1985
-
(1985)
Diabetes Metab Rev
, vol.1
, pp. 293-317
-
-
Amatruda, J.M.1
Livingston, J.N.2
Lockwood, D.H.3
-
3
-
-
0019473012
-
Effects of prednisolone and dexamethasone in vivo and in vitro: Studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes
-
De Pirro R, Green A, Kao MY, Olefsky JM: Effects of prednisolone and dexamethasone in vivo and in vitro: studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes. Diabetologia 21:149-153, 1981
-
(1981)
Diabetologia
, vol.21
, pp. 149-153
-
-
De Pirro, R.1
Green, A.2
Kao, M.Y.3
Olefsky, J.M.4
-
4
-
-
0016708685
-
Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes
-
Olefsky JM: Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest 56:1499-1508, 1975
-
(1975)
J Clin Invest
, vol.56
, pp. 1499-1508
-
-
Olefsky, J.M.1
-
5
-
-
0020050650
-
Glucocorticoid-induced insulin resistance: The importance of postbinding events in the regulation of insulin binding, action, and degradation in freshly isolated and primary cultures of rat hepatocytes
-
Caro JF, Amatruda JM: Glucocorticoid-induced insulin resistance: the importance of postbinding events in the regulation of insulin binding, action, and degradation in freshly isolated and primary cultures of rat hepatocytes. J Clin Invest 69:866-875, 1982
-
(1982)
J Clin Invest
, vol.69
, pp. 866-875
-
-
Caro, J.F.1
Amatruda, J.M.2
-
6
-
-
0021879053
-
Glucose tolerance and physical activity in a health survey of middle-aged subjects
-
Cederholm J, Wibell L: Glucose tolerance and physical activity in a health survey of middle-aged subjects. Acta Med Scand 217:373-378, 1985
-
(1985)
Acta Med Scand
, vol.217
, pp. 373-378
-
-
Cederholm, J.1
Wibell, L.2
-
7
-
-
0023026240
-
Lower prevalence of diabetes in female former college athletes compared with nonathletes
-
Frisch RE, Wyshak G, Albright TE, Albright NL, Schiff I: Lower prevalence of diabetes in female former college athletes compared with nonathletes. Diabetes 35:1101-1105, 1986
-
(1986)
Diabetes
, vol.35
, pp. 1101-1105
-
-
Frisch, R.E.1
Wyshak, G.2
Albright, T.E.3
Albright, N.L.4
Schiff, I.5
-
8
-
-
0021256269
-
Glucose tolerance in young and older athletes and sedentary men
-
Seals DR, Hagberg JM, Allen WK, Hurley BF, Dalsky GP, Ehsani AA, Holloszy JO: Glucose tolerance in young and older athletes and sedentary men. J Appl Physiol 56:1521-1525, 1984
-
(1984)
J Appl Physiol
, vol.56
, pp. 1521-1525
-
-
Seals, D.R.1
Hagberg, J.M.2
Allen, W.K.3
Hurley, B.F.4
Dalsky, G.P.5
Ehsani, A.A.6
Holloszy, J.O.7
-
9
-
-
0020033858
-
Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet
-
Grundleger ML, Thenen SW: Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet. Diabetes 31:232-237, 1982
-
(1982)
Diabetes
, vol.31
, pp. 232-237
-
-
Grundleger, M.L.1
Thenen, S.W.2
-
10
-
-
0018097666
-
In-vitro and in-vivo responsiveness of muscle and adipose tissue to insulin in rats rendered obese by a high-fat diet
-
Susini C, Lavau M: In-vitro and in-vivo responsiveness of muscle and adipose tissue to insulin in rats rendered obese by a high-fat diet Diabetes 27:114-120, 1978
-
(1978)
Diabetes
, vol.27
, pp. 114-120
-
-
Susini, C.1
Lavau, M.2
-
11
-
-
0022977709
-
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats
-
Storlien LH, James DE, Burleigh KM, Chisholm DJ, Kraegen EW: Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. Am J Physiol 251:E576-E583, 1986
-
(1986)
Am J Physiol
, vol.251
-
-
Storlien, L.H.1
James, D.E.2
Burleigh, K.M.3
Chisholm, D.J.4
Kraegen, E.W.5
-
12
-
-
0028089960
-
Diabetes and diabetes risk factors in second- and third-generation Japanese Americans in Seattle, Washington
-
Fujimoto WY, Bergstrom RW, Boyko EJ, Kinyoun JL, Leonetti DL, Newell-Morris LL, Robinson LR, Shuman WP, Stolov WC, Tsunehara CH, Wahl PW: Diabetes and diabetes risk factors in second- and third-generation Japanese Americans in Seattle, Washington. Diabetes Res Clin Pract 24 (Suppl.):S43-S52, 1994
-
(1994)
Diabetes Res Clin Pract
, vol.24
, Issue.SUPPL.
-
-
Fujimoto, W.Y.1
Bergstrom, R.W.2
Boyko, E.J.3
Kinyoun, J.L.4
Leonetti, D.L.5
Newell-Morris, L.L.6
Robinson, L.R.7
Shuman, W.P.8
Stolov, W.C.9
Tsunehara, C.H.10
Wahl, P.W.11
-
13
-
-
0025054595
-
A prospective population-based study of alcohol use and non-insulin-dependent diabetes mellitus
-
Holbrook TL, Barrett-Connor E, Wingard DL: A prospective population-based study of alcohol use and non-insulin-dependent diabetes mellitus. Am J Epidemiol 132:902-909, 1990
-
(1990)
Am J Epidemiol
, vol.132
, pp. 902-909
-
-
Holbrook, T.L.1
Barrett-Connor, E.2
Wingard, D.L.3
-
14
-
-
0024370286
-
Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats
-
Thorburn AW, Storlien LH, Jenkins AB, Khouri S, Kraegen EW: Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am J Clin Nutr 49:1155-1163, 1989
-
(1989)
Am J Clin Nutr
, vol.49
, pp. 1155-1163
-
-
Thorburn, A.W.1
Storlien, L.H.2
Jenkins, A.B.3
Khouri, S.4
Kraegen, E.W.5
-
15
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 s6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR: Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911, 1994
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
16
-
-
0027249346
-
Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of Pi3-kinase
-
Kanai F, Ito K, Todaka M, Hayashi H, Kamohara S, Ishii K, Okada T, Hazeki O, Ui M, Ebina Y: Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase. Biochem Biophys Res Commun 195:762-768, 1993
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 762-768
-
-
Kanai, F.1
Ito, K.2
Todaka, M.3
Hayashi, H.4
Kamohara, S.5
Ishii, K.6
Okada, T.7
Hazeki, O.8
Ui, M.9
Ebina, Y.10
-
17
-
-
0028124189
-
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes: Studies with a selective inhibitor wortmannin
-
Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M: Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes: studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 3568-3573
-
-
Okada, T.1
Kawano, Y.2
Sakakibara, T.3
Hazeki, O.4
Ui, M.5
-
18
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang SI, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN: The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736, 1995
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
19
-
-
0029160069
-
Protein kinase b (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602, 1995
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
20
-
-
0029009331
-
Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells
-
Sakaue H, Hara K, Noguchi T, Matozaki T, Kotani K, Ogawa W, Yonezawa K, Waterfield MD, Kasuga M: Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells. J Biol Chem 270:11304-11309, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 11304-11309
-
-
Sakaue, H.1
Hara, K.2
Noguchi, T.3
Matozaki, T.4
Kotani, K.5
Ogawa, W.6
Yonezawa, K.7
Waterfield, M.D.8
Kasuga, M.9
-
21
-
-
0028797745
-
Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: Evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase
-
Shepherd PR, Nave BT, Siddle K: Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase. Biochem J 305:25-28, 1995
-
(1995)
Biochem J
, vol.305
, pp. 25-28
-
-
Shepherd, P.R.1
Nave, B.T.2
Siddle, K.3
-
22
-
-
0028982829
-
Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression
-
Sutherland C, O'Brien RM, Granner DK: Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression. J Biol Chem 270:15501-15506, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 15501-15506
-
-
Sutherland, C.1
O'Brien, R.M.2
Granner, D.K.3
-
23
-
-
0030050975
-
Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway
-
Gabbay RA, Sutherland C, Gnudi L, Kahn BB, O'Brien RM, Granner DK, Flier JS: Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway. J Biol Chem 271:1890-1897, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 1890-1897
-
-
Gabbay, R.A.1
Sutherland, C.2
Gnudi, L.3
Kahn, B.B.4
O'Brien, R.M.5
Granner, D.K.6
Flier, J.S.7
-
24
-
-
0027484001
-
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus
-
Folli F, Saad MJ, Backer JM, Kahn CR: Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J Clin Invest 92:1787-1794, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 1787-1794
-
-
Folli, F.1
Saad, M.J.2
Backer, J.M.3
Kahn, C.R.4
-
25
-
-
0028964599
-
Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells
-
Saad MJ, Folli F, Kahn CR: Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells. Endocrinology 136:1579-1588, 1995
-
(1995)
Endocrinology
, vol.136
, pp. 1579-1588
-
-
Saad, M.J.1
Folli, F.2
Kahn, C.R.3
-
26
-
-
0027489828
-
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
-
Saad MJ, Folli F, Kahn JA, Kahn CR: Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92:2065-2072, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 2065-2072
-
-
Saad, M.J.1
Folli, F.2
Kahn, J.A.3
Kahn, C.R.4
-
27
-
-
0030066985
-
Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats
-
Carvalho CR, Brenelli SL, Silva AC, Nunes AL, Velloso LA, Saad MJ: Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats. Endocrinology 137:151-159, 1996
-
(1996)
Endocrinology
, vol.137
, pp. 151-159
-
-
Carvalho, C.R.1
Brenelli, S.L.2
Silva, A.C.3
Nunes, A.L.4
Velloso, L.A.5
Saad, M.J.6
-
28
-
-
0031019658
-
Defects in insulin signal transduction in liver and muscle of pregnant rats
-
Saad MJ, Maeda L, Brenelli SL, Carvalho CR, Paiva RS, Velloso LA: Defects in insulin signal transduction in liver and muscle of pregnant rats. Diabetologia 40:179-186, 1997
-
(1997)
Diabetologia
, vol.40
, pp. 179-186
-
-
Saad, M.J.1
Maeda, L.2
Brenelli, S.L.3
Carvalho, C.R.4
Paiva, R.S.5
Velloso, L.A.6
-
29
-
-
0028903232
-
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
-
Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL: Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest 95:2195-2204, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2195-2204
-
-
Goodyear, L.J.1
Giorgino, F.2
Sherman, L.A.3
Carey, J.4
Smith, R.J.5
Dohm, G.L.6
-
30
-
-
0022973181
-
In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin
-
James DE, Burleigh KM, Kraegen EW: In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin. J Biol Chem 261:6366-6374, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 6366-6374
-
-
James, D.E.1
Burleigh, K.M.2
Kraegen, E.W.3
-
31
-
-
0030911521
-
Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells
-
Ogihara T, Shin BC, Anai M, Katagiri H, Inukai K, Funaki M, Fukushima Y, Ishihara H, Takata K, Kikuchi M, Yazaki Y, Oka Y, Asano T: Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells. J Biol Chem 272:12868-12873, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 12868-12873
-
-
Ogihara, T.1
Shin, B.C.2
Anai, M.3
Katagiri, H.4
Inukai, K.5
Funaki, M.6
Fukushima, Y.7
Ishihara, H.8
Takata, K.9
Kikuchi, M.10
Yazaki, Y.11
Oka, Y.12
Asano, T.13
-
32
-
-
0030615068
-
P85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase), p50α, p55α and p85α, with different PI3-kinase activity elevating responses to insulin
-
Inukai K, Funaki M, Ogihara T, Katagiri H, Kanda A, Anai M, Fukushima Y, Hosaka T, Suzuki M, Shin BC, Takata K, Yazaki Y, Kikuchi M, Oka Y, Asano T: p85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase), p50α, p55α and p85α, with different PI3-kinase activity elevating responses to insulin. J Biol Chem 272:7873-7882, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 7873-7882
-
-
Inukai, K.1
Funaki, M.2
Ogihara, T.3
Katagiri, H.4
Kanda, A.5
Anai, M.6
Fukushima, Y.7
Hosaka, T.8
Suzuki, M.9
Shin, B.C.10
Takata, K.11
Yazaki, Y.12
Kikuchi, M.13
Oka, Y.14
Asano, T.15
-
33
-
-
0031984952
-
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via IRS-1 and IRS-2 in Zucker fatty rats
-
Anai M, Funaki M, Ogihara T, Terasaki J, Inukai K, Katagiri H, Fukushima Y, Yazaki Y, Kikuchi M, Oka Y, Asano T: Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via IRS-1 and IRS-2 in Zucker fatty rats. Diabetes 47:13-23, 1998
-
(1998)
Diabetes
, vol.47
, pp. 13-23
-
-
Anai, M.1
Funaki, M.2
Ogihara, T.3
Terasaki, J.4
Inukai, K.5
Katagiri, H.6
Fukushima, Y.7
Yazaki, Y.8
Kikuchi, M.9
Oka, Y.10
Asano, T.11
-
34
-
-
0024936235
-
Cellular alterations in liver, skeletal muscle, and adipose tissue responsible for insulin resistance in obesity and type II diabetes
-
Caro JF, Dohm LG, Portes WJ, Sinha MK: Cellular alterations in liver, skeletal muscle, and adipose tissue responsible for insulin resistance in obesity and type II diabetes. Diabetes Metab Rev 5:665-689, 1989
-
(1989)
Diabetes Metab Rev
, vol.5
, pp. 665-689
-
-
Caro, J.F.1
Dohm, L.G.2
Portes, W.J.3
Sinha, M.K.4
-
35
-
-
0028085078
-
The insulin signaling system
-
White MF, Kahn CR: The insulin signaling system. J Biol Chem 269:1-4, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 1-4
-
-
White, M.F.1
Kahn, C.R.2
-
36
-
-
0027424828
-
Molecular determinants of insulin action
-
Kahn CR, Folli F: Molecular determinants of insulin action. Horm Res 39 (Suppl. 3):93-101, 1993
-
(1993)
Horm Res
, vol.39
, Issue.3 SUPPL.
, pp. 93-101
-
-
Kahn, C.R.1
Folli, F.2
-
37
-
-
0028260280
-
Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
-
Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD: Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J 300:631-635, 1994
-
(1994)
Biochem J
, vol.300
, pp. 631-635
-
-
Clarke, J.F.1
Young, P.W.2
Yonezawa, K.3
Kasuga, M.4
Holman, G.D.5
-
38
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats
-
Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ, Storlien LH: Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 40:1397-1403, 1991
-
(1991)
Diabetes
, vol.40
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
Daley, E.A.4
Chisholm, D.J.5
Storlien, L.H.6
-
39
-
-
0029551666
-
Metabolic effects of troglitazone on fat-induced insulin resistance in the rat
-
Khoursheed M, Miles PD, Gao KM, Lee MK, Moossa AR, Olefeky JM: Metabolic effects of troglitazone on fat-induced insulin resistance in the rat. Metab Clin Exper 44:1489-1494, 1995
-
(1995)
Metab Clin Exper
, vol.44
, pp. 1489-1494
-
-
Khoursheed, M.1
Miles, P.D.2
Gao, K.M.3
Lee, M.K.4
Moossa, A.R.5
Olefeky, J.M.6
-
40
-
-
0022628695
-
In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: Assessment by euglycaemic clamp plus deoxyglucose administration
-
Kraegen EW, James DE, Storlien LH, Burleigh KM, Chisholm DJ: In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration. Diabetologia 29:192-198, 1986
-
(1986)
Diabetologia
, vol.29
, pp. 192-198
-
-
Kraegen, E.W.1
James, D.E.2
Storlien, L.H.3
Burleigh, K.M.4
Chisholm, D.J.5
-
41
-
-
0022996786
-
Effect of diet change on insulin action: Difference between muscles and adipocytes
-
Maegawa H, Kobayashi M, Ishibashi O, Takata Y, Shigeta Y: Effect of diet change on insulin action: difference between muscles and adipocytes. Am J Physiol 251:E616-E623, 1986
-
(1986)
Am J Physiol
, vol.251
-
-
Maegawa, H.1
Kobayashi, M.2
Ishibashi, O.3
Takata, Y.4
Shigeta, Y.5
-
42
-
-
0026666965
-
A high-fat diet worsens metabolic control in streptozotocin-treated rats by increasing hepatic glucose production
-
Traianedes K, Proietto J, O'Dea K: A high-fat diet worsens metabolic control in streptozotocin-treated rats by increasing hepatic glucose production. Metabolism 41:846-850, 1992
-
(1992)
Metabolism
, vol.41
, pp. 846-850
-
-
Traianedes, K.1
Proietto, J.2
O'Dea, K.3
-
44
-
-
0030987889
-
High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect
-
Zierath JR, Houseknecht KL, Gnudi L, Kahn BB: High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes 46:215-223, 1997
-
(1997)
Diabetes
, vol.46
, pp. 215-223
-
-
Zierath, J.R.1
Houseknecht, K.L.2
Gnudi, L.3
Kahn, B.B.4
-
45
-
-
0030798932
-
Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes
-
Ozanne SE, Nave BT, Wang CL, Shepherd FR, Prins J, Smith GD: Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes. Am J Physiol 273:E46-E51, 1997
-
(1997)
Am J Physiol
, vol.273
-
-
Ozanne, S.E.1
Nave, B.T.2
Wang, C.L.3
Shepherd, F.R.4
Prins, J.5
Smith, G.D.6
-
46
-
-
0030854777
-
Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle
-
Shepherd PR, Nave BT, Rincon J, Nolte LA, Bevan AP, Siddle K, Zierath JR, Wallberg-Henriksson H: Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle. J. Biol Chem 272:19000-19007, 1997
-
(1997)
J. Biol Chem
, vol.272
, pp. 19000-19007
-
-
Shepherd, P.R.1
Nave, B.T.2
Rincon, J.3
Nolte, L.A.4
Bevan, A.P.5
Siddle, K.6
Zierath, J.R.7
Wallberg-Henriksson, H.8
-
47
-
-
0027437376
-
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
-
Sun XJ, Crimmins DL, Myers MG Jr, Miralpeix M, White MF: Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol Cell Biol 13:7418-7428, 1993
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7418-7428
-
-
Sun, X.J.1
Crimmins, D.L.2
Myers M.G., Jr.3
Miralpeix, M.4
White, M.F.5
-
48
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
Sun XJ, Wang LM, Zhang Y, Yenush L, Myers MG Jr, Glasheen E, Lane WS, Pierce JH, White MF: Role of IRS-2 in insulin and cytokine signalling. Nature 377:173-177, 1995
-
(1995)
Nature
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.3
Yenush, L.4
Myers M.G., Jr.5
Glasheen, E.6
Lane, W.S.7
Pierce, J.H.8
White, M.F.9
-
49
-
-
0027212268
-
The new elements of insulin signaling: Insulin receptor substrate-1 and proteins with SH2 domains
-
Myers MG Jr, White MF: The new elements of insulin signaling: insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650, 1993
-
(1993)
Diabetes
, vol.42
, pp. 643-650
-
-
Myers M.G., Jr.1
White, M.F.2
-
50
-
-
0027450410
-
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity
-
Carpenter CL, Auger KR, Duckworth BC, Hou WM, Schaffhausen B, Cantley LC: A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol Cell Biol 13:1657-1665, 1993
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1657-1665
-
-
Carpenter, C.L.1
Auger, K.R.2
Duckworth, B.C.3
Hou, W.M.4
Schaffhausen, B.5
Cantley, L.C.6
-
51
-
-
0027953284
-
PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
-
Dhand R, Hiles I, Panayotou G, Roche S, Fry MJ, Gout I, Totty NF, Truong O, Vicendo P, Yonezawa K, Kasuga M, Courtneidge SA, Waterfield MD: PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J 13:522-533, 1994
-
(1994)
EMBO J
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
Kasuga, M.11
Courtneidge, S.A.12
Waterfield, M.D.13
-
52
-
-
0031015407
-
Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone
-
Antonucci T, Whitcomb R, McLain R, Lockwood D: Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone. Diabetes Care 20:188-193, 1907
-
(1907)
Diabetes Care
, vol.20
, pp. 188-193
-
-
Antonucci, T.1
Whitcomb, R.2
McLain, R.3
Lockwood, D.4
-
53
-
-
0029999139
-
Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients: Troglitazone study group
-
Kumar S, Boulton AJ, Beck-Nielsen H, Berthezene F, Muggeo M, Persson B, Spinas GA, Donoghue S, Lettis S, Stewart-Long P: Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients: Troglitazone Study Group. Diabetologia 39:701-709, 1996 (Erratum published in Diabetologia 39:1245, 1996)
-
(1996)
Diabetologia
, vol.39
, pp. 701-709
-
-
Kumar, S.1
Boulton, A.J.2
Beck-Nielsen, H.3
Berthezene, F.4
Muggeo, M.5
Persson, B.6
Spinas, G.A.7
Donoghue, S.8
Lettis, S.9
Stewart-Long, P.10
-
54
-
-
0029782274
-
-
Erratum published
-
Kumar S, Boulton AJ, Beck-Nielsen H, Berthezene F, Muggeo M, Persson B, Spinas GA, Donoghue S, Lettis S, Stewart-Long P: Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients: Troglitazone Study Group. Diabetologia 39:701-709, 1996 (Erratum published in Diabetologia 39:1245, 1996)
-
(1996)
Diabetologia
, vol.39
, pp. 1245
-
-
-
55
-
-
0028860995
-
Metabolic effects of darglitazone, an insulin sensitizer, in NIDDM subjects
-
Chaiken RL, Eckert-Norton M, Pasmantier R, Boden G, Ryan I, Gelfand RA, Lebovitz HE: Metabolic effects of darglitazone, an insulin sensitizer, in NIDDM subjects. Diabetologia 38:1307-1312, 1995
-
(1995)
Diabetologia
, vol.38
, pp. 1307-1312
-
-
Chaiken, R.L.1
Eckert-Norton, M.2
Pasmantier, R.3
Boden, G.4
Ryan, I.5
Gelfand, R.A.6
Lebovitz, H.E.7
-
56
-
-
6844222829
-
Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet
-
Terasaki J, Anai M, Funaki M, Shibata T, Inukai K, Ogihara T, Ishihara H, Katagiri H, Onishi Y, Sakoda H, Fukushima Y, Yazaki Y, Kikuchi M, Oka Y, Asano T: Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet. Diabetologia 41:400-409, 1998
-
(1998)
Diabetologia
, vol.41
, pp. 400-409
-
-
Terasaki, J.1
Anai, M.2
Funaki, M.3
Shibata, T.4
Inukai, K.5
Ogihara, T.6
Ishihara, H.7
Katagiri, H.8
Onishi, Y.9
Sakoda, H.10
Fukushima, Y.11
Yazaki, Y.12
Kikuchi, M.13
Oka, Y.14
Asano, T.15
-
57
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-artivated receptor gamma (PPAR gamma)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-artivated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
58
-
-
0028032417
-
Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and l6 myotubes
-
Zhang B, Szalkowski D, Diaz E, Hayes N, Smith R, Berger J: Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes. J Biol Chem 269:25735-25741, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 25735-25741
-
-
Zhang, B.1
Szalkowski, D.2
Diaz, E.3
Hayes, N.4
Smith, R.5
Berger, J.6
-
59
-
-
0026766036
-
Pioglitazone increases insulin sensitivity by activating insulin receptor kinase
-
Kobayashi M, Iwanishi M, Egawa K, Shigeta Y: Pioglitazone increases insulin sensitivity by activating insulin receptor kinase. Diabetes 41:476-483, 1992
-
(1992)
Diabetes
, vol.41
, pp. 476-483
-
-
Kobayashi, M.1
Iwanishi, M.2
Egawa, K.3
Shigeta, Y.4
-
60
-
-
0028884048
-
Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes: Association with increased insulin binding and cell-surface glut4 as measured by photoaffinity labeling
-
Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, Kirkham DM, Lister CA, Smith SA: Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes: association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling. Diabetes 44:1087-1092, 1995
-
(1995)
Diabetes
, vol.44
, pp. 1087-1092
-
-
Young, P.W.1
Cawthorne, Ma.2
Coyle, P.J.3
Holder, J.C.4
Holman, G.D.5
Kozka, I.J.6
Kirkham, D.M.7
Lister, C.A.8
Smith, S.A.9
-
61
-
-
15844415080
-
Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice
-
Zhang B, Graziano MP, Doebber TW, Leibowitz MD, White-Carrington S, Szalkowski DM, Hey PJ, Wu M, Cullinan CA, Bailey P, Lollmann B, Frederich R, Flier JS, Strader CD, Smith RG: Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice. J Biol Chem 271:9455-9459, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 9455-9459
-
-
Zhang, B.1
Graziano, M.P.2
Doebber, T.W.3
Leibowitz, M.D.4
White-Carrington, S.5
Szalkowski, D.M.6
Hey, P.J.7
Wu, M.8
Cullinan, C.A.9
Bailey, P.10
Lollmann, B.11
Frederich, R.12
Flier, J.S.13
Strader, C.D.14
Smith, R.G.15
-
62
-
-
0028305633
-
Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism
-
Sizer KM, Smith CL, Jacob CS, Swanson ML, Bleasdale JE: Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism. Mol Cell Endocrinol 103:1-12, 1994
-
(1994)
Mol Cell Endocrinol
, vol.103
, pp. 1-12
-
-
Sizer, K.M.1
Smith, C.L.2
Jacob, C.S.3
Swanson, M.L.4
Bleasdale, J.E.5
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