Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice

Drug Metabolism and Disposition

Volumn 39, Issue 6, 2011, Pages 966-973

  Porter, Todd D ^a,b   Banerjee, Subhashis ^b   Stolarczyk, Elzbieta I ^a   Zou, Ling ^a  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 REDUCTASE; FARNESOID X RECEPTOR; LIVER X RECEPTOR;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; CATABOLISM; CELL DIVISION; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ENZYME REPRESSION; FATTY ACID SYNTHESIS; GENETIC TRANSFECTION; HEPATOMA CELL; LIPIDOSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CELL LINE, TUMOR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMMUNOBLOTTING; LIPID METABOLISM; LIPIDOSES; LIVER; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; NADPH-FERRIHEMOPROTEIN REDUCTASE; PLASMIDS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; STEROL 14-DEMETHYLASE; TRANSFECTION; TRIGLYCERIDES;

MUS; RATTUS;

EID: 79956149056     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.038562     Document Type: Article

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