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Volumn 6, Issue 10, 2007, Pages 3976-3984

The disruption of hepatic cytochrome P450 reductase alters mouse lipid metabolism

Author keywords

Knock out; Lipidomics; Microarray; Oxidoreductase; Promoter analysis; Systems biology

Indexed keywords

CARBOXYLIC ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL ESTER; CYTOCHROME P450 REDUCTASE; MONOUNSATURATED FATTY ACID; OXIDOREDUCTASE; PHOSPHATIDYLCHOLINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL;

EID: 35649019357     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr0700448     Document Type: Article
Times cited : (22)

References (33)
  • 1
    • 0038507099 scopus 로고    scopus 로고
    • Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: Impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase
    • Gu, J.; Weng, Y.; Zhang, Q. Y.; Cui, H.; Behr, M.; Wu, L.; Yang, W.; Zhang, L.; Ding, X. Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase. J. Biol. Chem. 2003, 278 (28), 25895-25901.
    • (2003) J. Biol. Chem , vol.278 , Issue.28 , pp. 25895-25901
    • Gu, J.1    Weng, Y.2    Zhang, Q.Y.3    Cui, H.4    Behr, M.5    Wu, L.6    Yang, W.7    Zhang, L.8    Ding, X.9
  • 2
    • 0037790603 scopus 로고    scopus 로고
    • Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase
    • Henderson, C. J.; Otto, D. M.; Carrie, D.; Magnuson, M. A.; McLaren, A. W.; Rosewell, I.; Wolf, C. R. Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase. J. Biol. Chem. 2003, 278 (15), 13480-13486.
    • (2003) J. Biol. Chem , vol.278 , Issue.15 , pp. 13480-13486
    • Henderson, C.J.1    Otto, D.M.2    Carrie, D.3    Magnuson, M.A.4    McLaren, A.W.5    Rosewell, I.6    Wolf, C.R.7
  • 3
    • 24744466284 scopus 로고    scopus 로고
    • Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype
    • Weng, Y.; DiRusso, C. C.; Reilly, A. A.; Black, P. N.; Ding, X. Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype. J. Biol. Chem. 2005, 280 (36), 31686-31698.
    • (2005) J. Biol. Chem , vol.280 , Issue.36 , pp. 31686-31698
    • Weng, Y.1    DiRusso, C.C.2    Reilly, A.A.3    Black, P.N.4    Ding, X.5
  • 4
    • 0000778664 scopus 로고    scopus 로고
    • Regulation of bile acid synthesis
    • Chiang, J. Y. Regulation of bile acid synthesis. Front. Biosci. 1998, 3, d176-d193.
    • (1998) Front. Biosci , vol.3
    • Chiang, J.Y.1
  • 5
    • 0036009146 scopus 로고    scopus 로고
    • Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP
    • Davis, R. A.; Miyake, J. H.; Hui, T. Y.; Spann, N. J. Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP. J. Lipid Res. 2002, 43 (4), 533-543.
    • (2002) J. Lipid Res , vol.43 , Issue.4 , pp. 533-543
    • Davis, R.A.1    Miyake, J.H.2    Hui, T.Y.3    Spann, N.J.4
  • 6
    • 21744456583 scopus 로고    scopus 로고
    • Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice
    • Wang, X. J.; Chamberlain, M.; Vassieva, O.; Henderson, C. J.; Wolf, C. R. Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice. Biochem. J. 2005, 388 (Pt. 3), 857-867.
    • (2005) Biochem. J , vol.388 , Issue.PART. 3 , pp. 857-867
    • Wang, X.J.1    Chamberlain, M.2    Vassieva, O.3    Henderson, C.J.4    Wolf, C.R.5
  • 10
    • 19344372271 scopus 로고    scopus 로고
    • Systems biology: Its practice and challenges
    • Aderem, A. Systems biology: its practice and challenges. Cell 2005, 121 (4), 511-513.
    • (2005) Cell , vol.121 , Issue.4 , pp. 511-513
    • Aderem, A.1
  • 12
    • 0036846241 scopus 로고    scopus 로고
    • Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone
    • Watkins, S. M.; Reifsnyder, P. R.; Pan, H. J.; German, J. B.; Leiter, E. H. Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J. Lipid Res. 2002, 43 (11), 1809-1817.
    • (2002) J. Lipid Res , vol.43 , Issue.11 , pp. 1809-1817
    • Watkins, S.M.1    Reifsnyder, P.R.2    Pan, H.J.3    German, J.B.4    Leiter, E.H.5
  • 13
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch, J.; Lees, M.; Sloane Stanley, G. H. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 1957, 226 (1), 497-509.
    • (1957) J. Biol. Chem , vol.226 , Issue.1 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 14
    • 0035074235 scopus 로고    scopus 로고
    • Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or alpha-linolenic acids
    • Watkins, S. M.; Lin, T. Y.; Davis, R. M.; Ching, J. R.; DePeters, E. J.; Halpern, G. M.; Walzern, R. L.; German, J. B. Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or alpha-linolenic acids. Lipids 2001, 36 (3), 247-254.
    • (2001) Lipids , vol.36 , Issue.3 , pp. 247-254
    • Watkins, S.M.1    Lin, T.Y.2    Davis, R.M.3    Ching, J.R.4    DePeters, E.J.5    Halpern, G.M.6    Walzern, R.L.7    German, J.B.8
  • 16
    • 27744523967 scopus 로고    scopus 로고
    • The next generation of literature analysis: Integration of genomic analysis into text mining
    • Scherf, M.; Epple, A.; Werner, T. The next generation of literature analysis: integration of genomic analysis into text mining. Brief. Bioinform. 2005, 6 (3), 287-297.
    • (2005) Brief. Bioinform , vol.6 , Issue.3 , pp. 287-297
    • Scherf, M.1    Epple, A.2    Werner, T.3
  • 18
    • 0036295401 scopus 로고    scopus 로고
    • LXR alpha is the dominant regulator of CYP7A1 transcription
    • Gupta, S.; Pandak, W. M.; Hylemon, P. B. LXR alpha is the dominant regulator of CYP7A1 transcription. Biochem. Biophys. Res. Commun. 2002, 293 (1), 338-343.
    • (2002) Biochem. Biophys. Res. Commun , vol.293 , Issue.1 , pp. 338-343
    • Gupta, S.1    Pandak, W.M.2    Hylemon, P.B.3
  • 19
    • 33751162645 scopus 로고    scopus 로고
    • Transcriptional activation of CYP2C9, CYP1A1 and CYP1A2 by HNF4{alpha} requires coactivators PGC1{alpha} and SRC1
    • Martinez-Jimenez, C. P.; Castell, J. V.; Gomez-Lechon, M. J.; Jover, R. Transcriptional activation of CYP2C9, CYP1A1 and CYP1A2 by HNF4{alpha} requires coactivators PGC1{alpha} and SRC1. Mol. Pharmacol. 2006, 70 (5), 1681-1692.
    • (2006) Mol. Pharmacol , vol.70 , Issue.5 , pp. 1681-1692
    • Martinez-Jimenez, C.P.1    Castell, J.V.2    Gomez-Lechon, M.J.3    Jover, R.4
  • 20
    • 0033548431 scopus 로고    scopus 로고
    • Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption
    • Park, S. H.; Liu, X.; Hennighausen, L.; Davey, H. W.; Waxman, D. J. Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption. J. Biol. Chem. 1999, 274 (11), 7421-7430.
    • (1999) J. Biol. Chem , vol.274 , Issue.11 , pp. 7421-7430
    • Park, S.H.1    Liu, X.2    Hennighausen, L.3    Davey, H.W.4    Waxman, D.J.5
  • 21
    • 32644443742 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression
    • Patsouris, D.; Reddy, J. K.; Muller, M.; Kersten, S. Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. Endocrinology 2006, 147 (3), 1508-1516.
    • (2006) Endocrinology , vol.147 , Issue.3 , pp. 1508-1516
    • Patsouris, D.1    Reddy, J.K.2    Muller, M.3    Kersten, S.4
  • 22
    • 21344439074 scopus 로고    scopus 로고
    • Nuclear receptors and drug disposition gene regulation
    • Tirona, R. G.; Kim, R. B. Nuclear receptors and drug disposition gene regulation. J. Pharm. Sci. 2005, 94 (6), 1169-1186.
    • (2005) J. Pharm. Sci , vol.94 , Issue.6 , pp. 1169-1186
    • Tirona, R.G.1    Kim, R.B.2
  • 25
    • 0036283121 scopus 로고    scopus 로고
    • PPAEs: Transcriptional effectors of fatty acids and their derivatives
    • Hihi, A. K.; Michalik, L.; Wahli, W. PPAEs: transcriptional effectors of fatty acids and their derivatives. Cell. Mol. Life Sci. 2002, 59 (5), 790-798.
    • (2002) Cell. Mol. Life Sci , vol.59 , Issue.5 , pp. 790-798
    • Hihi, A.K.1    Michalik, L.2    Wahli, W.3
  • 26
    • 33645983221 scopus 로고    scopus 로고
    • LXRS and FXR: The yin and yang of cholesterol and fat metabolism
    • Kalaany, N. Y.; Mangelsdorf, D. J. LXRS and FXR: the yin and yang of cholesterol and fat metabolism. Annu. Rev. Physiol. 2006, 68, 159-191.
    • (2006) Annu. Rev. Physiol , vol.68 , pp. 159-191
    • Kalaany, N.Y.1    Mangelsdorf, D.J.2
  • 27
    • 0019481094 scopus 로고
    • Rates of sterol synthesis and uptake in the major organs of the rat in vivo
    • Turley, S. D.; Andersen, J. M.; Dietschy, J. M. Rates of sterol synthesis and uptake in the major organs of the rat in vivo. J. Lipid Res. 1981, 22 (4), 551-569.
    • (1981) J. Lipid Res , vol.22 , Issue.4 , pp. 551-569
    • Turley, S.D.1    Andersen, J.M.2    Dietschy, J.M.3
  • 28
    • 20544469710 scopus 로고    scopus 로고
    • Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis
    • Van Eck, M.; Pennings, M.; Hoekstra, M.; Out, R.; Van Berkel, T. J. Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis. Curr. Opin. Lipidol. 2005, 16 (3), 307-315.
    • (2005) Curr. Opin. Lipidol , vol.16 , Issue.3 , pp. 307-315
    • Van Eck, M.1    Pennings, M.2    Hoekstra, M.3    Out, R.4    Van Berkel, T.J.5
  • 30
    • 0034939632 scopus 로고    scopus 로고
    • Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: An adaptive metabolic system
    • Reddy, J. K.; Hashimoto, T. Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system. Annu. Rev. Nutr. 2001, 21, 193-230.
    • (2001) Annu. Rev. Nutr , vol.21 , pp. 193-230
    • Reddy, J.K.1    Hashimoto, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.